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RRTGDQLKADCRAAALAEVAVAGLAGLTVEGVARRASAAKTSVYRHWASVDDLLIDALAAACPREEVTVE GGHLRDDLLRSLHQLTGWLSGPAAPAVAAVLAERRRRPDLVDALYRDVFGTHGNRFTQTVIEHYAATGEI APRSVTPVVCDIGEALVIKHQIDTGELPDGSALEAIVDQAILPALGFPATSSGHA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3129 | - | - | 100% (196) | putative HTH-type transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 1e-13 | 31.72% (145) | putative TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5567 | - | 9e-11 | 27.81% (169) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 2e-19 | 31.32% (182) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3683 | - | 7e-14 | 27.87% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1167c | - | 2e-19 | 31.32% (182) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0300c | - | 4e-10 | 26.26% (179) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4284 | - | 1e-16 | 32.62% (187) | transcriptional regulatory protein |
| M. avium 104 | MAV_1309 | - | 1e-18 | 30.05% (183) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2910 | - | 2e-06 | 30.21% (96) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 1e-14 | 30.34% (178) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 2e-13 | 26.23% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1199c|M.bovis_AF2122/97 ----------------------------MTVSAPAKANPYR--RRGEVLE
Rv1167c|M.tuberculosis_H37Rv ----------------------------MTVSAPAKANPYR--RRGEVLE
MMAR_4284|M.marinum_M ----------------------------MAQLSEPMLTPYRSRRRGEVLE
MAV_1309|M.avium_104 MQRTLPAAVVRLLRREAADRNAHGYYQEMPQLTD--RTGSRSRRRGEVLE
Mflv_3683|M.gilvum_PYR-GCK ---------------------------------------MMTRRRGAELD
Mvan_2727|M.vanbaalenii_PYR-1 ----------------------------------------MGRRRGAELD
MSMEG_3129|M.smegmatis_MC2_155 -----------------------------------------MRRTGDQLK
MUL_1934|M.ulcerans_Agy99 -----------------------------MGAMTQTADRSAQVSPWSPRE
MAB_0300c|M.abscessus_ATCC_199 -----------------------------------MSTEKKPQIRGVNLE
TH_2910|M.thermoresistible__bu -----------------MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSR
Mb1199c|M.bovis_AF2122/97 RALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV
Rv1167c|M.tuberculosis_H37Rv RALYDATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAV
MMAR_4284|M.marinum_M RALYSATLAELIAVGYGRLTMEGIAARAQTGKAALYRRWASKHDLVQAAL
MAV_1309|M.avium_104 RALYEATLAELTEVGYGGLTMEGIAARAHTGKAALYRRWDTKCELVHAAL
Mflv_3683|M.gilvum_PYR-GCK AAIRSAVLDLLAGHGPEAVTMDAVAVAAGTSKPVLYRRWPDRRALLRDTL
Mvan_2727|M.vanbaalenii_PYR-1 AAIRAAVLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTL
MSMEG_3129|M.smegmatis_MC2_155 ADCRAAALAEVAVAGLAGLTVEGVARRASAAKTSVYRHWASVDDLLIDAL
MUL_1934|M.ulcerans_Agy99 AELLAVTLQLLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAF
MAB_0300c|M.abscessus_ATCC_199 RAVLAATLAQIEAVGIEQTRIAEIAARAGVHETSIYRRWKTLPRLLADAL
TH_2910|M.thermoresistible__bu ARLLDAATSLLTSGGVEAVTVDAVTRLSKVARTTLYRHFESTTHLLAEAF
.. : * : :: : . .. :**:: *: :.
Mb1199c|M.bovis_AF2122/97 QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP
Rv1167c|M.tuberculosis_H37Rv QYALPPVPEPRADRSARENLLAVFTANCEILAGKTALPSMEIVSQLLHEP
MMAR_4284|M.marinum_M QYAVPPPPEPRPGRSARENLLTVFTAHRDVLAGKTEFPGLVAIGQLIHEP
MAV_1309|M.avium_104 VFALPPVPELRSGRSARENLLAMFTAQRDLLAGKTAFPGIEVIQQLLHEP
Mflv_3683|M.gilvum_PYR-GCK MAVASTSFPRPDTGTFRGDLLAVLRAWAQLFTGDTGPLMRSVIVAVASDP
Mvan_2727|M.vanbaalenii_PYR-1 LGIATSAFPTVDTGGFRGDMLAVLRAWAALFTGDSAALMRSAIGAVTADP
MSMEG_3129|M.smegmatis_MC2_155 AAACPREEVTVEGGHLRDDLLRSLHQLTGWLSGPAAPAVAAVLAERRRRP
MUL_1934|M.ulcerans_Agy99 IEGVRQVAVAPNTGSLRDDLVKIGEGICG-QAHQQASTIRAVLVEVSRHP
MAB_0300c|M.abscessus_ATCC_199 IIHIDADIPIPDTGSLREDLMSLARGLAQFLETPHGDALMRGTVQVSDDP
TH_2910|M.thermoresistible__bu ERLLPQVTSPPATGDLRDQLIELVHRQAALIDEAPLHLTALAWLALGPDP
* ::: *
Mb1199c|M.bovis_AF2122/97 ELRAIFINSVWAPR-----LRIVESILQAGVRSGEIDPATLTPMTARIGP
Rv1167c|M.tuberculosis_H37Rv ELRAIFINSVWAPR-----LRIVESILQAGVRSGEIDPATLTPMTARIGP
MMAR_4284|M.marinum_M ELRAIFANSVVHPR-----LKIIDSVLRAAIREGDLDPDTVTPFTARIGP
MAV_1309|M.avium_104 EMRAIFADAVVRPR-----LKIVESILQSAVQDGDLDPKSITPLTARIGS
Mflv_3683|M.gilvum_PYR-GCK DLESTFRSDVLGMR-----KAEMTTLIGRAVERGEVRPDVPVELVRELGQ
Mvan_2727|M.vanbaalenii_PYR-1 ELAATFRTDVIGAR-----KQEMDAIITRGVQRGEVRADVPVDLVRELGQ
MSMEG_3129|M.smegmatis_MC2_155 DLVDALYRDVFGTHG----NRFTQTVIEHYAATGEIAPRSVTPVVCDIGE
MUL_1934|M.ulcerans_Agy99 ALSDALQRQFVDQR-----KALIQQVLQQAVDRGEITQAAITDELWDLLP
MAB_0300c|M.abscessus_ATCC_199 EVAEARR-EFWNRR-----LTAVEAIVQRALVRGEVRPGVDARTVVLTLG
TH_2910|M.thermoresistible__bu NSDARQPLAGLSARVIEQYRQPFDELLAGAAARDELDDFDTTLAIIQLLG
: :: .:: .
Mb1199c|M.bovis_AF2122/97 ALIHQHVLFTGSPPDREQLTRIIDAMILTTGERRES-----
Rv1167c|M.tuberculosis_H37Rv ALIHQHVLFTGSPPDREQLTRIIDAMILTTGERRES-----
MMAR_4284|M.marinum_M ALMNQHFILTGTPPNRRELALIVDTVIPPKRTSTCDNCDN-
MAV_1309|M.avium_104 ALINQHFLLNGSPPNRRELALIVDTVIPPRGSDRAAD----
Mflv_3683|M.gilvum_PYR-GCK SVLWHRLLITGDPITDELVTQLVDEVLIPVTRPYYDQ----
Mvan_2727|M.vanbaalenii_PYR-1 SVLWHRLLISGDPIDDEVVTRLVDEVLIPVTRPYYEV----
MSMEG_3129|M.smegmatis_MC2_155 ALVIKHQIDTGELPDGSALEAIVDQAILPALGFPATSSGHA
MUL_1934|M.ulcerans_Agy99 GYLIFRSIIPNRPPTPHTVQLLVDDFIMPGLTQATG-----
MAB_0300c|M.abscessus_ATCC_199 GYVHLWAAHLGQTADDLALDELVDLIIDGVSAGR-------
TH_2910|M.thermoresistible__bu PIVFAKLTGMKTLTPADRVRIVDDFLVAHRPPTPETA----
: : : * :