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TDTETTAEKEPVAGGNAGMGAEYLEVRGLTVDFDGFKAVNGVDLTLFQGDLRFLIGPNGAGKTTVIDAIT GLVPATGSVNKSGAELLGKKVHQIARLGVGRTFQTASVFEQLTVLQNLDIAAGAGRSPWSLLRRRRGVLP SIEEALETTGLADLADKPAGVLAHGQKQWLEIGMLLVQNADVLLLDEPVAGMSHEEREETGNLLRRIGGA RTVVVVEHDMDFMRAFATSVTVLARGQVIAEGTVAEVQANPKVQEVYLGTAAAGAEGIA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2979 | - | - | 100% (270) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3250 | - | 1e-36 | 35.74% (277) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6877 | - | 1e-31 | 36.21% (243) | branched-chain amino acid transport system ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 8e-20 | 28.82% (229) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3801 | - | 1e-131 | 88.89% (270) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 8e-20 | 28.82% (229) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_00590 | - | 5e-19 | 29.82% (228) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2623c | - | 8e-38 | 38.02% (263) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_0171 | - | 8e-21 | 28.85% (253) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_1785 | - | 1e-19 | 29.61% (233) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_4087 | - | 1e-129 | 91.86% (258) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_4925 | - | 1e-20 | 28.85% (253) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2593 | - | 1e-133 | 90.37% (270) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 --------------------------------MT--------YAIVVADA
Rv2397c|M.tuberculosis_H37Rv --------------------------------MT--------YAIVVADA
MAV_1785|M.avium_104 --------------------------------MTDAGTDRGDIAITVRDA
MSMEG_2979|M.smegmatis_MC2_155 --------------------MTDTETTAEKEPVAGGNAGMGAEYLEVRGL
TH_4087|M.thermoresistible__bu ------------------------MTTAAREPVAGGNAGMRAEYLEVRGL
Mflv_3801|M.gilvum_PYR-GCK -------------------MSDVQASIAAKEPAEGGNAGMGAQYLEVRGL
Mvan_2593|M.vanbaalenii_PYR-1 -------------------MTEVEASTAGKEPVEGGNAGMGAQYLEVRGL
MAB_2623c|M.abscessus_ATCC_199 MTKHRDSSLDDEQDSVEMLQAEIEEGSDEGESGVPVDPGEAEVLLEVKDL
MMAR_0171|M.marinum_M -----------------------MSSPESKTDNETGDSQPGTSALEAVDL
MUL_4925|M.ulcerans_Agy99 -----------------------MSSPESKTDNETGDSQPGTSALEAVDL
MLBr_00590|M.leprae_Br4923 ------------------------------MSSACTVPETPEVVIRLRGV
: .
Mb2419c|M.bovis_AF2122/97 TKRYGD--FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDT
Rv2397c|M.tuberculosis_H37Rv TKRYGD--FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDT
MAV_1785|M.avium_104 YKRYGD--FVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDT
MSMEG_2979|M.smegmatis_MC2_155 TVDFDG--FKAVNGVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVP-AT
TH_4087|M.thermoresistible__bu TVDFDG--FKAVSGVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVP-AT
Mflv_3801|M.gilvum_PYR-GCK TVDFDG--FKAVSDVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVS-AS
Mvan_2593|M.vanbaalenii_PYR-1 TVDFDG--FKAVSDVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVP-AT
MAB_2623c|M.abscessus_ATCC_199 TLKFGG--LQALDGVSFDIRRGEILGLVGPNGAGKTTCFNAITGVYKPTS
MMAR_0171|M.marinum_M VKSYPGSDANAVDGLNLVIPRGVVYCLLGRNGAGKTTTIRMATTLLTPTS
MUL_4925|M.ulcerans_Agy99 VKSYPGSDANAVDGLNLVIPRGVVYCLLGRNGAGKTTTIRMATTLLTPTS
MLBr_00590|M.leprae_Br4923 CKHYGS--ILAVSNLDLDIHSAEVLALLGPNGAGKTTTVEMCEGFVRPDA
: . *:. :.: : . : *:* .*:**:* . . :
Mb2419c|M.bovis_AF2122/97 GTITINGRDVTRVPP---QRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK
Rv2397c|M.tuberculosis_H37Rv GTITINGRDVTRVPP---QRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK
MAV_1785|M.avium_104 GTVTIYGRDVTRVPP---QRRGIGFVFQHYAAFKHLTVRDNVAYGLKVRK
MSMEG_2979|M.smegmatis_MC2_155 GSVNKSGAELLGKKVHQIARLGVGRTFQTASVFEQLTVLQNLDIAAGAGR
TH_4087|M.thermoresistible__bu GSVNKSGVELLGKKVHQIARLGVGRTFQTASVFETLTVLQNLDIAAGAGR
Mflv_3801|M.gilvum_PYR-GCK GSVNKSGVELLGKKVNQIARLGVGRTFQTASVFEQLTVLQNLDIAAGAGR
Mvan_2593|M.vanbaalenii_PYR-1 GSVNKSGVELLGKKVHQIARRGVGRTFQTASVFEQLTVLQNLDIAAGAGR
MAB_2623c|M.abscessus_ATCC_199 GSIVFNGKPLRRLRRHQITRRGIARTFQNIRLFGEMTALENVAVGTDARH
MMAR_0171|M.marinum_M GQLEVLGVPVDNTTQ---LRPLIGVALQEVALDLWMSPVEQIRMSLAMAG
MUL_4925|M.ulcerans_Agy99 GQLEVLGVPVDNTTQ---LRPLIGVALQEVALDLWMSPVEQIRMSLAMAG
MLBr_00590|M.leprae_Br4923 GTIEVLGLDPITDNAR--LRARIGVMLQGGGGYPAARAGEMLNLVASYAA
* : * * :. :* : :
Mb2419c|M.bovis_AF2122/97 ---------------RPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQR
Rv2397c|M.tuberculosis_H37Rv ---------------RPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQR
MAV_1785|M.avium_104 ---------------RPKAEIKAKVDNLLEVVGLSGFQGRYPNQLSGGQR
MSMEG_2979|M.smegmatis_MC2_155 SPWSL---------LRRRRGVLPSIEEALETTGLADLADKPAGVLAHGQK
TH_4087|M.thermoresistible__bu SWRTL---------LRRRGAVLPQITETLQTIGLADLADEPAGTLAHGQK
Mflv_3801|M.gilvum_PYR-GCK SVWTL---------LRRRNGVLPAIEQALHTTGLTHLADKPAGVLAHGQK
Mvan_2593|M.vanbaalenii_PYR-1 SVWTL---------LRRRNGVLPAIEQALHTIGLTHLADKPAGVLAHGQK
MAB_2623c|M.abscessus_ATCC_199 KTSVLGALLRTPRHRREEHYAVDVGMGLLDFVGIADDADVKAKNLPYGSQ
MMAR_0171|M.marinum_M ---------------WPKSDRKRREGELVEQFGLGKYLNRKVGALSGGMR
MUL_4925|M.ulcerans_Agy99 ---------------WPKSDRKRREGELVEQFGLGKYLNRKVGALSGGMR
MLBr_00590|M.leprae_Br4923 D--------------------PLDPEWLLETLGLTDVARTTYRRLSGGQQ
:. *: *. * :
Mb2419c|M.bovis_AF2122/97 QRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVL
Rv2397c|M.tuberculosis_H37Rv QRMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVL
MAV_1785|M.avium_104 QRMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVL
MSMEG_2979|M.smegmatis_MC2_155 QWLEIGMLLVQNADVLLLDEPVAGMSHEEREETGNLLRRIGGA--RTVVV
TH_4087|M.thermoresistible__bu QWLEIGMLLVQNADVLLLDEPVAGMSHEEREQTGNLLRRIGGE--RTVVV
Mflv_3801|M.gilvum_PYR-GCK QWLEIGMLLVQNADVLLLDEPVAGMSAEEREETGNLLRRIGAE--RTVVV
Mvan_2593|M.vanbaalenii_PYR-1 QWLEIGMLLVQNADVLLLDEPVAGMSAEEREETGNLLRRIGAE--RTVVV
MAB_2623c|M.abscessus_ATCC_199 RRLEIARALATEPKLLCLDEPAAGFTPSEKDSLIELIQRIRDYG-YTVLL
MMAR_0171|M.marinum_M RRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIRLLRSEG-RTVVL
MUL_4925|M.ulcerans_Agy99 RRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIRLLRSEG-RTVVL
MLBr_00590|M.leprae_Br4923 QRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDG-VTVVL
: : :. :. ..:: **** ..: : : : *.::
Mb2419c|M.bovis_AF2122/97 VTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVST
Rv2397c|M.tuberculosis_H37Rv VTHDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLGAVST
MAV_1785|M.avium_104 VTHDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFLGAVST
MSMEG_2979|M.smegmatis_MC2_155 VEHDMDFMRAFATSVTVLARGQVIAEGTVAEVQANPK--VQEVYLGTAAA
TH_4087|M.thermoresistible__bu VEHDMDFMRAFATSVTVLARGQVIAEGTVEEVQANPK--VQEVYLGTAAE
Mflv_3801|M.gilvum_PYR-GCK VEHDMDFMRAFATSVTVLARGQVIAEGSVAEVQANPR--VQEVYLGTAAA
Mvan_2593|M.vanbaalenii_PYR-1 VEHDMDFMRAFATSVTVLARGQVIAEGSVTEVQANPK--VQEVYLGTAAA
MAB_2623c|M.abscessus_ATCC_199 IEHDMKLVMGVTDRIVVLEFGRKIADGLPAEVRNDPA--VIEAYLGVADE
MMAR_0171|M.marinum_M TTHDMDEAVSLADEVGIIKDGVLVAAGSTQEFTRSHGFAVDISAPQEITD
MUL_4925|M.ulcerans_Agy99 TTHDMDEAVLLADEVGIIKDGVLVAAGSTQEFTRSHGFAVDISAPQEITD
MLBr_00590|M.leprae_Br4923 TTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSAPPRLD
*: .: : :: * * :.
Mb2419c|M.bovis_AF2122/97 LNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRV
Rv2397c|M.tuberculosis_H37Rv LNGSLVRPHDIRVGRTPNMAVAAADGTAGSTGVLRAVVDRVVVLGFEVRV
MAV_1785|M.avium_104 LNGTLVRPHDIRVGRTPEMAVAAEDGTAESTGVARAIVDRVVKLGFEVRV
MSMEG_2979|M.smegmatis_MC2_155 GAEGIA--------------------------------------------
TH_4087|M.thermoresistible__bu LPEEAH--------------------------------------------
Mflv_3801|M.gilvum_PYR-GCK GADGIELVEENS--------------------------------------
Mvan_2593|M.vanbaalenii_PYR-1 GADGIELVEENS--------------------------------------
MAB_2623c|M.abscessus_ATCC_199 DFHGPGWLDSAPPDSESER-------------------------------
MMAR_0171|M.marinum_M DAVRQLAGAGYPMQRKGSSAVTGSLDSASASEIGSLATVLDRLGLAGANI
MUL_4925|M.ulcerans_Agy99 DAVRQLAGAGYPMQRKGSSAVTGSLDSASASEIGSLATVLDRLGLAGANI
MLBr_00590|M.leprae_Br4923 LSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQINVLTTNM
Mb2419c|M.bovis_AF2122/97 ELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG---VSG
Rv2397c|M.tuberculosis_H37Rv ELTSAATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGG---VSG
MAV_1785|M.avium_104 ELTSAATGGPFTAQITRGDAEALALREGDTVYVRATRVPPITAGATTVPA
MSMEG_2979|M.smegmatis_MC2_155 --------------------------------------------------
TH_4087|M.thermoresistible__bu --------------------------------------------------
Mflv_3801|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2593|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0171|M.marinum_M EIRSTSLRDAFLEATQ----------------------------------
MUL_4925|M.ulcerans_Agy99 EIRSTSLRDAFLEATQ----------------------------------
MLBr_00590|M.leprae_Br4923 RVEQHSLEDVFLDLTGRKLR------------------------------
Mb2419c|M.bovis_AF2122/97 VDDAGVERVKVTST
Rv2397c|M.tuberculosis_H37Rv VDDAGVERVKVTST
MAV_1785|M.avium_104 VSRDGADEATLTSA
MSMEG_2979|M.smegmatis_MC2_155 --------------
TH_4087|M.thermoresistible__bu --------------
Mflv_3801|M.gilvum_PYR-GCK --------------
Mvan_2593|M.vanbaalenii_PYR-1 --------------
MAB_2623c|M.abscessus_ATCC_199 --------------
MMAR_0171|M.marinum_M --------------
MUL_4925|M.ulcerans_Agy99 --------------
MLBr_00590|M.leprae_Br4923 --------------