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MSSPESKTDNETGDSQPGTSALEAVDLVKSYPGSDANAVDGLNLVIPRGVVYCLLGRNGAGKTTTIRMAT TLLTPTSGQLEVLGVPVDNTTQLRPLIGVALQEVALDLWMSPVEQIRMSLAMAGWPKSDRKRREGELVEQ FGLGKYLNRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIRLLRSEGRTVVLTT HDMDEAVSLADEVGIIKDGVLVAAGSTQEFTRSHGFAVDISAPQEITDDAVRQLAGAGYPMQRKGSSAVT GSLDSASASEIGSLATVLDRLGLAGANIEIRSTSLRDAFLEATQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0171 | - | - | 100% (324) | ATP-binding protein ABC transporter |
| M. marinum M | MMAR_3263 | - | 6e-43 | 36.04% (308) | ATP-binding protein ABC transporter |
| M. marinum M | MMAR_1771 | drrA | 4e-34 | 32.32% (297) | daunorubicin-DIM-transport ATP-binding protein ABC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2961 | drrA | 7e-37 | 32.23% (301) | daunorubicin-DIM-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_1936 | - | 2e-42 | 36.66% (311) | daunorubicin resistance ABC transporter ATPase subunit |
| M. tuberculosis H37Rv | Rv2936 | drrA | 5e-36 | 31.89% (301) | daunorubicin-DIM-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_02352 | - | 1e-35 | 32.12% (302) | putative antibiotic resistance efflux protein |
| M. abscessus ATCC 19977 | MAB_1689 | - | 1e-136 | 79.61% (304) | daunorubicin resistance ABC transporter ATP-binding subunit |
| M. avium 104 | MAV_3250 | - | 9e-44 | 36.04% (308) | daunorubicin resistance ATP-binding protein DrrA |
| M. smegmatis MC2 155 | MSMEG_6766 | - | 7e-36 | 40.44% (225) | ABC transporter, ATP-binding protein, NodI family protein |
| M. thermoresistible (build 8) | TH_2788 | - | 2e-28 | 33.45% (287) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_4925 | - | 1e-180 | 99.69% (324) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_4796 | - | 7e-44 | 37.54% (309) | daunorubicin resistance ABC transporter ATPase subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2961|M.bovis_AF2122/97 ---------------MRNDDMAVVVNGVRKTYGK-GKIVALDDVSFKVRR
Rv2936|M.tuberculosis_H37Rv ---------------MRNDDMAVVVNGVRKTYGK-GKIVALDDVSFKVRR
MLBr_02352|M.leprae_Br4923 ---------------MRNNDKAVMVRGVRKTYGK-GKIIALDDVSFDVDR
MAV_3250|M.avium_104 ---------------MSAP--AIEVEGLTKKFG--GSTLALAGVDFSVPA
Mflv_1936|M.gilvum_PYR-GCK ----------------MPFPPAIEALDLVKRFG---DQTAVAGVSFVVPP
Mvan_4796|M.vanbaalenii_PYR-1 MADKSVGPMSVCAYTVDAMESAIEAIDLVKRFGDTLDNPAVDGVSFAVPP
MSMEG_6766|M.smegmatis_MC2_155 ------------------MSAAVEVRGLSKSYGR---RPAVRDLDLDVGY
TH_2788|M.thermoresistible__bu -----------------MMAAMIELTALTKVFGR---TRAVDDLTCTVEP
MMAR_0171|M.marinum_M -MSSPESKTDNETGDSQPGTSALEAVDLVKSYPG-SDANAVDGLNLVIPR
MUL_4925|M.ulcerans_Agy99 -MSSPESKTDNETGDSQPGTSALEAVDLVKSYPG-SDANAVDGLNLVIPR
MAB_1689|M.abscessus_ATCC_1997 -----------MTTDTQ--IPALRAAELVKAYPG-SDARAVDGLDLTIPQ
: : * : *: .: :
Mb2961|M.bovis_AF2122/97 GEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAIIAGYDVVSEPAGVRRSI
Rv2936|M.tuberculosis_H37Rv GEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAIIAGYDVVSEPAGVRRSI
MLBr_02352|M.leprae_Br4923 GEVIGLLGPNGAGKTTMVDILSTLTRPDRGLATVAGYDVVSEPAGVRRSI
MAV_3250|M.avium_104 GTVCGLLGHNGAGKTTTINILSTLIRPTSGRARVAGYDVVRQPAEVRASI
Mflv_1936|M.gilvum_PYR-GCK GTVLGLLGPNGAGKTTTVRMMTTLTEPTSGTARVAGFDVRTHPDEVRRHM
Mvan_4796|M.vanbaalenii_PYR-1 GTVLGLLGPNGAGKTTTVRMMTTLTEPTSGTARVAGYDVRAQPDDVRRHM
MSMEG_6766|M.smegmatis_MC2_155 GEIFAILGPNGAGKTTTVEILEGNRRRDSGEVLVLGEDPGRAGRQWRARI
TH_2788|M.thermoresistible__bu GVVTGFLGPNGAGKTTTMRLILGLDRPTSGTATIDGRRYRDLRDPLR-TV
MMAR_0171|M.marinum_M GVVYCLLGRNGAGKTTTIRMATTLLTPTSGQLEVLGVPVDN-TTQLRPLI
MUL_4925|M.ulcerans_Agy99 GVVYCLLGRNGAGKTTTIRMATTLLTPTSGQLEVLGVPVDN-TTQLRPLI
MAB_1689|M.abscessus_ATCC_1997 GIVYCLLGRNGAGKTTTIRMATTLLAPTRGELEVLGVPVDN-TKELRPLI
* : :** ******* : : * : * * :
Mb2961|M.bovis_AF2122/97 MVTGQQVAVDDALSGEQNLVLFGRLWGLSKSAARKRAAELLEQFSLVHAG
Rv2936|M.tuberculosis_H37Rv MVTGQQVAVDDALSGEQNLVLFGRLWGLSKSAARKRAAELLEQFSLVHAG
MLBr_02352|M.leprae_Br4923 MVTGQQVAVDDQLSGEQNLILFGRLYGLSKSVARVRTQELLEQFDLLHAG
MAV_3250|M.avium_104 GMAGQFTGMDPMLTGRENLVLFGRLRGLNRRRAKARADELLEQFNLVDAA
Mflv_1936|M.gilvum_PYR-GCK GLTGQVATVDELLTGRENIRMIGGLYGIRRRDLKNLGDQLLHQFSLTDAA
Mvan_4796|M.vanbaalenii_PYR-1 GLTGQVATVDELLTGRENIRMIGGLYGIRRKDLDRLGDQLLHQFSLTDAA
MSMEG_6766|M.smegmatis_MC2_155 GIVLQEVSDAGMLTVGETVQMFSACYGTAR-----APADVLELVGLRHAS
TH_2788|M.thermoresistible__bu GALLDARAVHPARSARNHLRWLAAANRIPQR----RVDEVLELVGLTAVA
MMAR_0171|M.marinum_M GVALQEVALDLWMSPVEQIRMSLAMAGWPKSDRKRREGELVEQFGLGKYL
MUL_4925|M.ulcerans_Agy99 GVALQEVALDLWMSPVEQIRMSLAMAGWPKSDRKRREGELVEQFGLGKYL
MAB_1689|M.abscessus_ATCC_1997 GVALQEVALDLWMSPVEQIRMSLAIAGWPKARRKAREDELVEQFGLSTYV
: : : : : :::. ..*
Mb2961|M.bovis_AF2122/97 KRRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVA
Rv2936|M.tuberculosis_H37Rv KRRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVA
MLBr_02352|M.leprae_Br4923 KRRVGTYSGGMRRRIDIACGLVVQPQVAFLDEPTTGLDPRSRQAIWDLVA
MAV_3250|M.avium_104 DRRLSTYSGGMYRRVDLASALVVPPKVLFLDEPTTGLDPRSRRDVWALVS
Mflv_1936|M.gilvum_PYR-GCK DRPVRSYSGGMRRRLDLAVSLLASPPVLFLDEPTTGLDPRSRSELWDVLR
Mvan_4796|M.vanbaalenii_PYR-1 DRVVRSYSGGMRRRLDLAVSLLASPPVLFLDEPTTGLDPRSRSELWDVLR
MSMEG_6766|M.smegmatis_MC2_155 RSRVRTLSGGQRRRLDVALGIIGGPELVFLDEPTTGFDPEARQQFWELIR
TH_2788|M.thermoresistible__bu ARPAGTLSLGMSQRLGIAGALLGDPPVLLFDEPVNGLDPEGIRWVRTLMR
MMAR_0171|M.marinum_M NRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIR
MUL_4925|M.ulcerans_Agy99 NRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIR
MAB_1689|M.abscessus_ATCC_1997 NRKVGALSGGMRRRVDVALAVAHNPQMLFLDEPSSGLDIEGKQEVWNAIR
: * * :*:.:* .: * : ::*** .*:* .. . :
Mb2961|M.bovis_AF2122/97 SFKKLGIATLLTTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDT
Rv2936|M.tuberculosis_H37Rv SFKKLGIATLLTTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDT
MLBr_02352|M.leprae_Br4923 SFKQIGIATLLTTQYLEEADELSDRIILIDHGTVIAEGTASELKHRVGET
MAV_3250|M.avium_104 SLRVQGISVLLTTQYLEEADVLSDSIVVIDHGRVIASGTSEELKRAVGTS
Mflv_1936|M.gilvum_PYR-GCK GLVAQGTTLLLTTQYLEEADQLADNIVVIDRGRIIAEGSPLHLKQQAGRA
Mvan_4796|M.vanbaalenii_PYR-1 GLVAQGTTLLLTTQYLEEADQLADNIVVIDRGHIIAEGSPLELKQQAGRA
MSMEG_6766|M.smegmatis_MC2_155 LLAADGTTIVLTTHYLEEAAALADRVAVIADGNVVAVDSPTRLTRHV-DT
TH_2788|M.thermoresistible__bu TMAAEGRTVLVSSHLLAEMANTADRLLVIGRGRLIASTSVAEFVGSTAAE
MMAR_0171|M.marinum_M LLRSEGRTVVLTTHDMDEAVSLADEVGIIKDGVLVAAGSTQEFTRSHGFA
MUL_4925|M.ulcerans_Agy99 LLRSEGRTVVLTTHDMDEAVLLADEVGIIKDGVLVAAGSTQEFTRSHGFA
MAB_1689|M.abscessus_ATCC_1997 LLRSEGRTVVLTTHDMDEAVSLADEVGIVKSGRLVASGSTQEFTRSHGYA
: * : ::::: : * :* : :: * ::* : .:
Mb2961|M.bovis_AF2122/97 FCEIVPRDLKDLDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLV
Rv2936|M.tuberculosis_H37Rv FCEIVPRDLKDLDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLV
MLBr_02352|M.leprae_Br4923 FCEIVPRDLKDLGTVVAALGSLLPERSRAMLTPTSDRITMPAPDGTQTLI
MAV_3250|M.avium_104 YCQVTPANPAELPQVAAALTGLEG----IEIDSDTGSVSVFAPDGVATLV
Mflv_1936|M.gilvum_PYR-GCK SLVVTVADAADLESARGLLARTGAE---VYVDAGARRLTATA-DGLDDMV
Mvan_4796|M.vanbaalenii_PYR-1 SLVVTVGDAADLEGARTLLGQTGAE---VFVDAGARRLTASA-DGLDDMI
MSMEG_6766|M.smegmatis_MC2_155 AATVRWMEGGHVHEERTEFP-----------------------------T
TH_2788|M.thermoresistible__bu RVRVRSPEMDTLRGLLADAGVEVR------LEPDGAALTVRG----AAPE
MMAR_0171|M.marinum_M VDISAPQEITDDAVRQLAGAGYPMQ-----RKGSSAVTGSLDSASASEIG
MUL_4925|M.ulcerans_Agy99 VDISAPQEITDDAVRQLAGAGYPMQ-----RKGSSAVTGSLDSASASEIG
MAB_1689|M.abscessus_ATCC_1997 VEVSADSVIPEEAAGRLAEAGYALR-----RTDSGTLSGTLDSASAADLG
Mb2961|M.bovis_AF2122/97 EAARRIDEARIELADIALRRPSLDDVFLAMTTDPTESLTHLVSGSAR
Rv2936|M.tuberculosis_H37Rv EAARRIDEARIELADIALRRPSLDHVFLAMTTDPTESLTHLVSGSAR
MLBr_02352|M.leprae_Br4923 EAARRIDEVSVELADIALRRPSLDDVFLSMTTDPSESLSHLAAGAMR
MAV_3250|M.avium_104 EVFRRVDALGLELADISLRKPSLDEAFLHLTERT-------VARS--
Mflv_1936|M.gilvum_PYR-GCK KVAGWLRDSGITVDDIGLSRPSLDDVFLMLTGHRTDDTEEVGA----
Mvan_4796|M.vanbaalenii_PYR-1 RVAEWLRDSGIAVDDIGLSRPSLDDVFLTLTGHRTEDSEEIGA----
MSMEG_6766|M.smegmatis_MC2_155 ELIRQRSRVGAELAQLTVTRPSLEDAYLHLIGRT-------------
TH_2788|M.thermoresistible__bu VVGELAARNGITLHELSVQRASLEDAYLELTDAAVEYRAVPR-----
MMAR_0171|M.marinum_M SLATVLDRLGLAGANIEIRSTSLRDAFLEATQ---------------
MUL_4925|M.ulcerans_Agy99 SLATVLDRLGLAGANIEIRSTSLRDAFLEATQ---------------
MAB_1689|M.abscessus_ATCC_1997 ALSAELDRVGLGAASIEVRSTSLRDAFLEVTQ---------------
.: : .** ..:*