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TEVEASTAGKEPVEGGNAGMGAQYLEVRGLTVDFDGFKAVSDVDLTLFQGDLRFLIGPNGAGKTTVIDAI TGLVPATGSVNKSGVELLGKKVHQIARRGVGRTFQTASVFEQLTVLQNLDIAAGAGRSVWTLLRRRNGVL PAIEQALHTIGLTHLADKPAGVLAHGQKQWLEIGMLLVQNADVLLLDEPVAGMSAEEREETGNLLRRIGA ERTVVVVEHDMDFMRAFATSVTVLARGQVIAEGSVTEVQANPKVQEVYLGTAAAGADGIELVEENS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2593 | - | - | 100% (277) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2844 | - | 3e-35 | 37.05% (251) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2845 | - | 3e-23 | 30.71% (241) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 7e-22 | 31.00% (229) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3801 | - | 1e-146 | 95.31% (277) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 7e-22 | 31.00% (229) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 1e-19 | 27.68% (224) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2623c | - | 7e-36 | 36.03% (272) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3715 | cysA1 | 8e-22 | 30.28% (251) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-21 | 31.33% (233) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_2979 | - | 1e-133 | 90.37% (270) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_4087 | - | 1e-125 | 89.53% (258) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 7e-22 | 30.28% (251) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 --------------------------------MT--------YAIVVADA
Rv2397c|M.tuberculosis_H37Rv --------------------------------MT--------YAIVVADA
MAV_1785|M.avium_104 --------------------------------MTDAGTDRGDIAITVRDA
MMAR_3715|M.marinum_M --------------------------MKKETSLTGPG--TGGHAIVVRDA
MUL_3658|M.ulcerans_Agy99 --------------------------------MTGPG--TGGHAIVVRDA
MLBr_01089|M.leprae_Br4923 -----------------------------------------MAEIVLEHV
Mvan_2593|M.vanbaalenii_PYR-1 -------------------MTEVEASTAGKEPVEGGNAGMGAQYLEVRGL
Mflv_3801|M.gilvum_PYR-GCK -------------------MSDVQASIAAKEPAEGGNAGMGAQYLEVRGL
MSMEG_2979|M.smegmatis_MC2_155 --------------------MTDTETTAEKEPVAGGNAGMGAEYLEVRGL
TH_4087|M.thermoresistible__bu ------------------------MTTAAREPVAGGNAGMRAEYLEVRGL
MAB_2623c|M.abscessus_ATCC_199 MTKHRDSSLDDEQDSVEMLQAEIEEGSDEGESGVPVDPGEAEVLLEVKDL
: :
Mb2419c|M.bovis_AF2122/97 TKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTG
Rv2397c|M.tuberculosis_H37Rv TKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTG
MAV_1785|M.avium_104 YKRYG-DFVALDHVDFVVPTGSLTALLGPSGSGKSTLLRTIAGLDQPDTG
MMAR_3715|M.marinum_M FKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSG
MUL_3658|M.ulcerans_Agy99 FKQYG-DFVALDHVDFVVPAGSLTALLGPSGSGKSTLLRTIAGLDQPDSG
MLBr_01089|M.leprae_Br4923 NKNYPNGATAVHDLSITVADGEFLILIGPSGCGKTTTLNMIAGLEDISSG
Mvan_2593|M.vanbaalenii_PYR-1 TVDFD-GFKAVSDVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVP-ATG
Mflv_3801|M.gilvum_PYR-GCK TVDFD-GFKAVSDVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVS-ASG
MSMEG_2979|M.smegmatis_MC2_155 TVDFD-GFKAVNGVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVP-ATG
TH_4087|M.thermoresistible__bu TVDFD-GFKAVSGVDLTLFQGDLRFLIGPNGAGKTTVIDAITGLVP-ATG
MAB_2623c|M.abscessus_ATCC_199 TLKFG-GLQALDGVSFDIRRGEILGLVGPNGAGKTTCFNAITGVYKPTSG
: . *: :.: : *.: *:**.*.**:* : *:*: :*
Mb2419c|M.bovis_AF2122/97 TITINGRDVT---RVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK-
Rv2397c|M.tuberculosis_H37Rv TITINGRDVT---RVPPQRRGIGFVFQHYAAFKHLTVRDNVAFGLKIRK-
MAV_1785|M.avium_104 TVTIYGRDVT---RVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKVRK-
MMAR_3715|M.marinum_M NITINGRDVT---RVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRK-
MUL_3658|M.ulcerans_Agy99 NITINGRDVT---RVPPQRRGIGFVFQHYAAFKHLTVRDNVAYGLKIRK-
MLBr_01089|M.leprae_Br4923 ELRIDGDRVN---EKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLMLAK-
Mvan_2593|M.vanbaalenii_PYR-1 SVNKSGVELLGKKVHQIARRGVGRTFQTASVFEQLTVLQNLDIAAGAGRS
Mflv_3801|M.gilvum_PYR-GCK SVNKSGVELLGKKVNQIARLGVGRTFQTASVFEQLTVLQNLDIAAGAGRS
MSMEG_2979|M.smegmatis_MC2_155 SVNKSGAELLGKKVHQIARLGVGRTFQTASVFEQLTVLQNLDIAAGAGRS
TH_4087|M.thermoresistible__bu SVNKSGVELLGKKVHQIARLGVGRTFQTASVFETLTVLQNLDIAAGAGRS
MAB_2623c|M.abscessus_ATCC_199 SIVFNGKPLRRLRRHQITRRGIARTFQNIRLFGEMTALENVAVGTDARHK
: * : .:. .** : :*. :*: :
Mb2419c|M.bovis_AF2122/97 --------------RPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQ
Rv2397c|M.tuberculosis_H37Rv --------------RPKAEIKAKVDNLLQVVGLSGFQSRYPNQLSGGQRQ
MAV_1785|M.avium_104 --------------RPKAEIKAKVDNLLEVVGLSGFQGRYPNQLSGGQRQ
MMAR_3715|M.marinum_M --------------RPKAEIRDKVDNLLEVVGLSGFHGRYPNQLSGGQRQ
MUL_3658|M.ulcerans_Agy99 --------------RPKAEIRDKVDNLLEVVGLSGFHGRYPDQLSGGQRQ
MLBr_01089|M.leprae_Br4923 --------------VKKAEIAQKVSETAQILDLTDLLDRKPSQLSGGQRQ
Mvan_2593|M.vanbaalenii_PYR-1 VWTL---------LRRRNGVLPAIEQALHTIGLTHLADKPAGVLAHGQKQ
Mflv_3801|M.gilvum_PYR-GCK VWTL---------LRRRNGVLPAIEQALHTTGLTHLADKPAGVLAHGQKQ
MSMEG_2979|M.smegmatis_MC2_155 PWSL---------LRRRRGVLPSIEEALETTGLADLADKPAGVLAHGQKQ
TH_4087|M.thermoresistible__bu WRTL---------LRRRGAVLPQITETLQTIGLADLADEPAGTLAHGQKQ
MAB_2623c|M.abscessus_ATCC_199 TSVLGALLRTPRHRREEHYAVDVGMGLLDFVGIADDADVKAKNLPYGSQR
. . .:: . . *. *.::
Mb2419c|M.bovis_AF2122/97 RMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLV
Rv2397c|M.tuberculosis_H37Rv RMALARALAVDPEVLLLDEPFGALDAKVREELRAWLRRLHDEVHVTTVLV
MAV_1785|M.avium_104 RMALARALAVDPQVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLV
MMAR_3715|M.marinum_M RMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLV
MUL_3658|M.ulcerans_Agy99 RMALARALAVDPEVLLLDEPFGALDAKVREDLRAWLRRLHDEVHVTTVLV
MLBr_01089|M.leprae_Br4923 RVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGEIARLQRRLGATTVYV
Mvan_2593|M.vanbaalenii_PYR-1 WLEIGMLLVQNADVLLLDEPVAGMSAEEREETGNLLRRIGAE--RTVVVV
Mflv_3801|M.gilvum_PYR-GCK WLEIGMLLVQNADVLLLDEPVAGMSAEEREETGNLLRRIGAE--RTVVVV
MSMEG_2979|M.smegmatis_MC2_155 WLEIGMLLVQNADVLLLDEPVAGMSHEEREETGNLLRRIGGA--RTVVVV
TH_4087|M.thermoresistible__bu WLEIGMLLVQNADVLLLDEPVAGMSHEEREQTGNLLRRIGGE--RTVVVV
MAB_2623c|M.abscessus_ATCC_199 RLEIARALATEPKLLCLDEPAAGFTPSEKDSLIELIQRIRDYG-YTVLLI
: :. :. ... : :*** . : . : : *: *.: :
Mb2419c|M.bovis_AF2122/97 THDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG-----
Rv2397c|M.tuberculosis_H37Rv THDQAEALDVADRIAVLHKGRIEQVGSPTDVYDAPANAFVMSFLG-----
MAV_1785|M.avium_104 THDQAEALDVADRIAVLNQGRIEQIGSPTEVYDAPTNAFVMSFLG-----
MMAR_3715|M.marinum_M THDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPANAFVMSFLG-----
MUL_3658|M.ulcerans_Agy99 THDQAEALDVADRIAVLNSGRIEQVGSPTEVYDAPTNAFVMSFLG-----
MLBr_01089|M.leprae_Br4923 THDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERPVNLFVAGFIGSPVMN
Mvan_2593|M.vanbaalenii_PYR-1 EHDMDFMRAFATSVTVLARGQVIAEGSVTEVQANPK--VQEVYLG-----
Mflv_3801|M.gilvum_PYR-GCK EHDMDFMRAFATSVTVLARGQVIAEGSVAEVQANPR--VQEVYLG-----
MSMEG_2979|M.smegmatis_MC2_155 EHDMDFMRAFATSVTVLARGQVIAEGTVAEVQANPK--VQEVYLG-----
TH_4087|M.thermoresistible__bu EHDMDFMRAFATSVTVLARGQVIAEGTVEEVQANPK--VQEVYLG-----
MAB_2623c|M.abscessus_ATCC_199 EHDMKLVMGVTDRIVVLEFGRKIADGLPAEVRNDPA--VIEAYLG-----
** . :.*: * * :: * . ::*
Mb2419c|M.bovis_AF2122/97 ----------------------AVSTLNGSLVRPHDIRVGRTPNMAVAAA
Rv2397c|M.tuberculosis_H37Rv ----------------------AVSTLNGSLVRPHDIRVGRTPNMAVAAA
MAV_1785|M.avium_104 ----------------------AVSTLNGTLVRPHDIRVGRTPEMAVAAE
MMAR_3715|M.marinum_M ----------------------AVSALNGALVRPHDIRVGRTPEMAVAAA
MUL_3658|M.ulcerans_Agy99 ----------------------AVSALNGALVRPHDIRVGRTPEMAVAAA
MLBr_01089|M.leprae_Br4923 FFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPDRVIVGVRPEHLTDAK
Mvan_2593|M.vanbaalenii_PYR-1 -----------------------------------TAAAGADGIELVEEN
Mflv_3801|M.gilvum_PYR-GCK -----------------------------------TAAAGADGIELVEEN
MSMEG_2979|M.smegmatis_MC2_155 -----------------------------------TAAAGAEGIA-----
TH_4087|M.thermoresistible__bu -----------------------------------TAAELPEEAH-----
MAB_2623c|M.abscessus_ATCC_199 -----------------------------------VADEDFHGPGWLDSA
Mb2419c|M.bovis_AF2122/97 DGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAE
Rv2397c|M.tuberculosis_H37Rv DGTAGSTG---VLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAE
MAV_1785|M.avium_104 DGTAESTG---VARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGDAE
MMAR_3715|M.marinum_M DGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAE
MUL_3658|M.ulcerans_Agy99 DGTGESTG---VTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAE
MLBr_01089|M.leprae_Br4923 LIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTGCD-VYSAQLDELASE
Mvan_2593|M.vanbaalenii_PYR-1 S-------------------------------------------------
Mflv_3801|M.gilvum_PYR-GCK S-------------------------------------------------
MSMEG_2979|M.smegmatis_MC2_155 --------------------------------------------------
TH_4087|M.thermoresistible__bu --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 PPDSESER------------------------------------------
Mb2419c|M.bovis_AF2122/97 ALALREGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST-------
Rv2397c|M.tuberculosis_H37Rv ALALREGDTVYVRATRVPPIAGG---VSGVDDAGVERVKVTST-------
MAV_1785|M.avium_104 ALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA-------
MMAR_3715|M.marinum_M ALALQEGDTVYVRATRVPPIAGA---APAVPDDGAGSTPSAAQIGVGGQ-
MUL_3658|M.ulcerans_Agy99 ALALQEGDTVYVRATRVPPIAGA---APAVPDDGAGSTPRAAQIGVGGQ-
MLBr_01089|M.leprae_Br4923 LEVRENQFVARVSAESKMAIGESIELAFGTAKIAVFDADSGVNLTVSAPT
Mvan_2593|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3801|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2979|M.smegmatis_MC2_155 --------------------------------------------------
TH_4087|M.thermoresistible__bu --------------------------------------------------
MAB_2623c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2419c|M.bovis_AF2122/97 --
Rv2397c|M.tuberculosis_H37Rv --
MAV_1785|M.avium_104 --
MMAR_3715|M.marinum_M --
MUL_3658|M.ulcerans_Agy99 --
MLBr_01089|M.leprae_Br4923 DA
Mvan_2593|M.vanbaalenii_PYR-1 --
Mflv_3801|M.gilvum_PYR-GCK --
MSMEG_2979|M.smegmatis_MC2_155 --
TH_4087|M.thermoresistible__bu --
MAB_2623c|M.abscessus_ATCC_199 --