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TRSPAVFFVSSEFHFSDRFPQWKSTEAATPTNEKQRDKARFAAELDRIGFDAIFITDFLGLNRTLIRHSG PRSFEPVTLAGYLAAHTERIGLVITVSTQFSEPYTVARELASLDRLSDGRAGWNVVTSFNGETNYGYTQI PAPRERYRRAREFLDVTKALWTSWDADAIIADRDAEIYVDTDRVHDIGWSGEHFRVHQALDLPPSPQVFP LIAQAGASDDGIALAADTAEVVFVASPDIDAGKRYYRRLKAAVVAAGRHADDLKVLPGIRIYLGDTDEQA WAAYSAELTDLDLERAREAITYEIGGLDLSDLDLDDHIPLDRFPDRAELERTGRRVSRALIYREWVETGA YPRLRDFLVRYATSFGHFQIVGTAETAADIITQWIDEGAADGFTLLGGSSFARIAGDLIPLLRQRGVFRD DVAPARLRDRLGTRTPGLPENQRVVERIAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2843 | ssuD | - | 100% (451) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_1162 | - | 5e-70 | 38.55% (415) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_2842 | ssuD | 1e-56 | 33.41% (419) | nitrilotriacetate monooxygenase component A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 3e-06 | 33.33% (96) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0250 | - | 6e-43 | 30.50% (400) | hypothetical protein Mflv_0250 |
| M. tuberculosis H37Rv | Rv0953c | - | 3e-06 | 33.33% (96) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4125 | - | 2e-63 | 39.45% (398) | putative nitrilotriacetate monooxygenase |
| M. marinum M | MMAR_0703 | - | 2e-51 | 32.58% (445) | FMNH2-utilizing oxygenase |
| M. avium 104 | MAV_3809 | - | 2e-51 | 35.10% (416) | dibenzothiophene desulfurization enzyme A |
| M. thermoresistible (build 8) | TH_4079 | - | 2e-63 | 37.62% (404) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 7e-09 | 25.00% (216) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 4e-53 | 32.92% (401) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2843|M.smegmatis_MC2_155 -----MTRSPAVFFVSSEFHFSDRFPQWKSTEAATPTNEKQRDKARFAAE
MAB_4125|M.abscessus_ATCC_1997 -----MSSRNGRQLHLLAFGNVRAGGAWRLPGVRNGPANQLNTLVATAKA
TH_4079|M.thermoresistible__bu ------------LPETRLSG-----------------ITDIDHYLELARI
Mvan_6020|M.vanbaalenii_PYR-1 ----------MMHLITWLMGNSYHAAGWRHQLAWERTAMRLDVLIEIAKI
MMAR_0703|M.marinum_M ---------MIRKPVHLAAHFPGVNNTTVWADPGAGSQIEFESFVHLART
Mflv_0250|M.gilvum_PYR-GCK MTDSAKRKAHLLGFVQHGVMNHASTMWAHPRDKVGYHWSRPEYWRDLGRT
MAV_3809|M.avium_104 MAE--QRQLHLAGFFSAGNVTHAHGAWRHVGATNGFLTG--EFYKQIART
Mb0978c|M.bovis_AF2122/97 ----------------------------MHYGLVLFTSDRGITPAAAARL
Rv0953c|M.tuberculosis_H37Rv ----------------------------MHYGLVLFTSDRGITPAAAARL
MUL_4507|M.ulcerans_Agy99 ------MALLFHWFLPTYGDSRGLVAGGHGLPMSGNRPATLRYLNQIAAA
.
MSMEG_2843|M.smegmatis_MC2_155 LDRIGFDAIFITDFLGLN-RTLIRHSGPRS-----------FEPVTLAGY
MAB_4125|M.abscessus_ATCC_1997 AEAAKFDAVFFADGLNFGPKATWAHKSTED-----------FEPLTATSY
TH_4079|M.thermoresistible__bu AERGKLDAIFFADHPVLKGKTEFRPFDA-------------LDPVTLVTA
Mvan_6020|M.vanbaalenii_PYR-1 AEEAKLDALFVADGNGVRNMDKVGLFEANTPSAR----PTVYDPVTLMAA
MMAR_0703|M.marinum_M AERGLFDFFFLAEGLRLREHRGRIHDLDVVGR---------PDTFTLLAA
Mflv_0250|M.gilvum_PYR-GCK MERGLFDAMFIADELAPYTTYKGSSDPVVKFAGQC---PVH-EPASVVPI
MAV_3809|M.avium_104 LERGKFDLLFLPDGLAIEDSYGENLETGVGLGGQG---AVALEPTSVIAT
Mb0978c|M.bovis_AF2122/97 AESHGFRTFYVPEHTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGA
Rv0953c|M.tuberculosis_H37Rv AESHGFRTFYVPEHTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGA
MUL_4507|M.ulcerans_Agy99 AESNGFEAVLTPAGLWCEDAWLTT------------------------AM
: : . .
MSMEG_2843|M.smegmatis_MC2_155 LAAHTERIGLVITVST-QFSEPYTVARELASLDRLSDGRAGWNVVTSFN-
MAB_4125|M.abscessus_ATCC_1997 LAAVTERLGLVVTGSS-TFQPPYHLARQLLSLDHLSSGRAGWNLVTSFAQ
TH_4079|M.thermoresistible__bu LSTATTHIGLVATAST-TYTEPYGLARRFATLDHVSRGRAGWNIVTTANA
Mvan_6020|M.vanbaalenii_PYR-1 ISQHTKHIGLVGTAST-TYESPWVVARRFASLDHLSNGRASWNVVTGSNP
MMAR_0703|M.marinum_M LAGVTDRIGLTGTINT-TFNEPFEVARQFATLDHLSEGRAGWNIVTSSDA
Mflv_0250|M.gilvum_PYR-GCK VGAFTKHLGIGITLST-SFVPPYMMARQLSTLDHLTGGRVGWNIVTSYSK
MAV_3809|M.avium_104 MAAVTERLGLGATVST-TYYPPYHVARVFATLDNLSDGRISWNVVTSLND
Mb0978c|M.bovis_AF2122/97 ASAVTSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNT
Rv0953c|M.tuberculosis_H37Rv ASAVTSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNT
MUL_4507|M.ulcerans_Agy99 LVGTTKTLKFLVALRP-GLVSPTLAAQMATTFQQQSGGRLLVNVVTGGEA
* : : : * *: :::. : ** .:
MSMEG_2843|M.smegmatis_MC2_155 -GETNYGYTQIPAPRERYRRAREFLDVTKALWTSWDADAIIADRDAEIYV
MAB_4125|M.abscessus_ATCC_1997 AAAANFGERGFLPHDERYRLAEETLQVVKSLWHSLEPDTVIEDRAAGIYS
TH_4079|M.thermoresistible__bu AAAANFGRPAHPDPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAPRFV
Mvan_6020|M.vanbaalenii_PYR-1 GDSENFGLAHHPDRDSRYARAEEFVSACKALWNSWDEDAFVERKDTGQYL
MMAR_0703|M.marinum_M FTGANFRRGGYLDHADRYQRAEEFLTVARKFWDSWAPGAVLADIENGDYV
Mflv_0250|M.gilvum_PYR-GCK SEFQAMGKENLTPRDKRYEVVEEYMQLLYQLWDSWDDDAIVYDRDNGVFA
MAV_3809|M.avium_104 SEARNFGVDEHLEHDIRYDRADEFLEAVKKLWSSWSEDALLLDKIGGRFA
Mb0978c|M.bovis_AF2122/97 DELVDHG----VPPGRRRTMLREYLEAMRALWT-----------------
Rv0953c|M.tuberculosis_H37Rv DELVDHG----VPPGRRRTMLREYLEAMRALWT-----------------
MUL_4507|M.ulcerans_Agy99 HEQRAYG--DFLDKQQRYRRTGEFLHVVRQLWAS----------------
* * : :*
MSMEG_2843|M.smegmatis_MC2_155 DTDRVHDIGWSGEHFRVHQALDLPPSPQ-VFPLIAQAGASDDGIALAADT
MAB_4125|M.abscessus_ATCC_1997 DINKIHVANHDGEFHKVKGPLGVTPSRQ-GHPVIFQAGSSTTGRAFAARH
TH_4079|M.thermoresistible__bu DPDKIHAIDHRGEHFSVAGPLEVPRSPQ-GHPVLFQAGSSEPGKQLAAKY
Mvan_6020|M.vanbaalenii_PYR-1 NARKVRVPDYKGRHLSVKGPLNVSRSPQ-GRPVLFHAGQSEGGRRLAARH
MMAR_0703|M.marinum_M DPERIRSVEHSGPQFEVRGFATLPAGPQ-GHPVLLQAGDSEQGRAFGARH
Mflv_0250|M.gilvum_PYR-GCK DPAKVREVNFQGEFFQSRGRHFVAPSPQ-KRPVLWQAGSSAQGREFASRH
MAV_3809|M.avium_104 DPKKVQYVNHRGHWLSVRGPLQVPRSRQ-GEPVILQAGLSPRGRRFAGRW
Mb0978c|M.bovis_AF2122/97 ----QEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWIARS
Rv0953c|M.tuberculosis_H37Rv ----QEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWIARS
MUL_4507|M.ulcerans_Agy99 ----GQPVTFEGEHIHVHQAQLGRLPDP--PPPVFFGGSSESAGAVAARY
. * * : .. : .
MSMEG_2843|M.smegmatis_MC2_155 AEVVFVASPDIDAGKRYYRRLKAAVVAAGRHADDLKVLPGIRIYLGDTDE
MAB_4125|M.abscessus_ATCC_1997 AEVVFTGQTDVERAKNFYRQLHQEARAAGRTFAPL-VTPSLGVVVGSTEA
TH_4079|M.thermoresistible__bu AEAIFTAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGGTEE
Mvan_6020|M.vanbaalenii_PYR-1 ADCIFEAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGRTES
MMAR_0703|M.marinum_M ADAMFTLHSSLRDGQRYYADVKGRARSYGRDPDQLKVFPAATFVIGDTPD
Mflv_0250|M.gilvum_PYR-GCK AESVFGIFPTPKSMRAYATDIRTRASDAGRDPESVKLIYGLQTIIDRDKG
MAV_3809|M.avium_104 AEAVFSVSPNLDIMRAVYQDIKAHVAAAGRDPEQTKVFTAVMPVLGETEQ
Mb0978c|M.bovis_AF2122/97 ADGWITTPRDVDID------------------EPVKLLQDIWAAAGRD--
Rv0953c|M.tuberculosis_H37Rv ADGWITTPRDVDID------------------EPVKLLQDIWAAAGRD--
MUL_4507|M.ulcerans_Agy99 ADTYLTWGEPLSAVGKKIDWIRGLAADHGRALSYGLRIHVITRDTAEEAW
*: :
MSMEG_2843|M.smegmatis_MC2_155 QAWAAYSAELTDLDLERAREAITYEIGGLDLSDLDLDDHIPLDRFPDRAE
MAB_4125|M.abscessus_ATCC_1997 EALAAESTIYEHFIPEYQ-AGWLLEVD-VNVVGADLDGPVPASAFPDSTE
TH_4079|M.thermoresistible__bu EARRIQRRLEDLTVPDYGLEQLSRIVG-YRVGRDDLDRRLQFGSDDPPAI
Mvan_6020|M.vanbaalenii_PYR-1 EAVELYSELNSLISPDLGVDFLAKAVS-EDLTGYPVDGPMPDLS--APVV
MMAR_0703|M.marinum_M QAGEKARQISYQQVSGATAIAMLEQVWGRDLSDYDPDGPLPDIDPIADAA
Mflv_0250|M.gilvum_PYR-GCK RANDRYAEFVENVQIESALGILSGHTG-FDFSTLGLD----DNVVDADVQ
MAV_3809|M.avium_104 VARERLEYLNSLVHPEVGLSTLSSHSG-LDLSKYPLDTKFSDIVADLGDR
Mb0978c|M.bovis_AF2122/97 --------------------------------------------------
Rv0953c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4507|M.ulcerans_Agy99 RVADRLLAGIDPADIERMQANLARSESEGQRRMAELHGGVLDQLEIAPNL
MSMEG_2843|M.smegmatis_MC2_155 LERTGRRVSRALIYREWVETGAYPRLRDFLVRYATSFGHFQIVG-TAETA
MAB_4125|M.abscessus_ATCC_1997 THQT------ALAGYKHLATVGNPTVREFLYRTLNAFG-TRFVG-SAEQV
TH_4079|M.thermoresistible__bu HMQS------RYALVRRLVSTENLTVRELLLRLSGGRGHRVFAG-TPEQV
Mvan_6020|M.vanbaalenii_PYR-1 GGNS------IRGQLDAIAKAEQLTVRQMYERVVPTMGNTALIG-TATQI
MMAR_0703|M.marinum_M ISQGRVRHADPVAVARRYRERSQAENLSIRELVIAVTSRQQFVG-TPSHI
Mflv_0250|M.gilvum_PYR-GCK GIRG-----LFDAILEAKDG-APVTVREAAQIYGVSMG-APVAVGTPADV
MAV_3809|M.avium_104 HVPT-----MLQMFSAVAGGGADLTLAELGRRYGTNVGFVPQWAGTAEQI
Mb0978c|M.bovis_AF2122/97 -------------------------------------GLPQIVALDVKPV
Rv0953c|M.tuberculosis_H37Rv -------------------------------------GLPQIVALDVKPV
MUL_4507|M.ulcerans_Agy99 WAGVG---------------------------LVRGGAGTALVG-SHQEV
.
MSMEG_2843|M.smegmatis_MC2_155 ADIITQWIDEGAADGFTLLGG---SSFARIAGDLIPLLRQRGVFRDDVAP
MAB_4125|M.abscessus_ATCC_1997 ADQIELWFSEGAADGFILSTSGLPGQFELFTEHVVPILVRRGLFRAEYTG
TH_4079|M.thermoresistible__bu ADTIEEWFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRTEYTG
Mvan_6020|M.vanbaalenii_PYR-1 ADVMEEWYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRRHYTG
MMAR_0703|M.marinum_M ADEIDRYVQADACDGFILVPHLTPHGLDEFVDRVVPLLQERGAFRTAYTG
Mflv_0250|M.gilvum_PYR-GCK ADQMEQYLDEGDCNGFMMLATDTPGCFNDMTELLVPELQKRGRFRTRYPG
MAV_3809|M.avium_104 ADQLVSHFEAGAADGFIISAAYLPGIYEEFVDQVVPLLQQRGVFRTEYEG
Mb0978c|M.bovis_AF2122/97 PDKLARWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV--------
Rv0953c|M.tuberculosis_H37Rv PDKLARWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV--------
MUL_4507|M.ulcerans_Agy99 AERIIEYARLG-ISHFILSGYPHLEEAYWFGEGVLPILERKRLWHRPHGS
.: : . . : : . *
MSMEG_2843|M.smegmatis_MC2_155 ARLRDRLGTRTPGLPENQRVVERIAR
MAB_4125|M.abscessus_ATCC_1997 STLREHLALPWP-VP--ARPPALLA-
TH_4079|M.thermoresistible__bu TTLRDHLGLPRPRNRFTTGRPVAAAS
Mvan_6020|M.vanbaalenii_PYR-1 STLRENLGLPPVDN-----SPFAT--
MMAR_0703|M.marinum_M QTLRDHLGLAGLPS------------
Mflv_0250|M.gilvum_PYR-GCK TTLRESLREY----------------
MAV_3809|M.avium_104 ATLREHLGLARPEVGSI---------
Mb0978c|M.bovis_AF2122/97 --------------------------
Rv0953c|M.tuberculosis_H37Rv --------------------------
MUL_4507|M.ulcerans_Agy99 SPHSAALPVAHSSVN-----------