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TGRKHLHLNLNLLATGRHDHSWRSQPDVIGPTDTAHFREVARIAERGLFDSLFLADSLALDGEAYRRPWR ACDPIVLFSALSQVTEHIGFIATVNALFAEPFTIARQIATLDHISGGRAGWNIVTSLNPAARANFSKAAA IDPEDRYRKAEEAVRVVRSLWDSFEPDAVRADQRSGTYLDADKVHAIDHTGDFFSVAGPGVVPQTPQGRP VIVQAGDSERLREMAGRWADAIFTVQRDIGSGRKFAQDAKHRARQHGRSPDELTILPGLFVVVGSTEAEA LARKAEIDAFVDVEAERDQLAERIGADPRLLVLDKPVPTAILDAPTDSPSVSPAFAKALVTQSQTEGLTV RDLLTRNPGGHRYVVGSPESVADDLELWFREGAADGFNLNIDRLPDGLAAFVDHVVPVLQERGLFRREYS TTTLRGHLSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2842 | ssuD | - | 100% (431) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_4590 | ssuD | e-106 | 45.65% (425) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_1162 | - | 2e-99 | 44.96% (427) | nitrilotriacetate monooxygenase component A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 5e-07 | 27.59% (232) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0250 | - | 7e-54 | 31.57% (453) | hypothetical protein Mflv_0250 |
| M. tuberculosis H37Rv | Rv0953c | - | 5e-07 | 27.59% (232) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4125 | - | 9e-77 | 42.00% (431) | putative nitrilotriacetate monooxygenase |
| M. marinum M | MMAR_0703 | - | 3e-76 | 39.00% (441) | FMNH2-utilizing oxygenase |
| M. avium 104 | MAV_3425 | - | 6e-83 | 41.59% (428) | nitrilotriacetate monooxygenase component A |
| M. thermoresistible (build 8) | TH_4079 | - | 1e-103 | 49.13% (401) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 3e-07 | 23.91% (230) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 4e-66 | 36.30% (438) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2842|M.smegmatis_MC2_155 -MTGR-KHLHLNLNLLATGRHDHSWR-SQPDVIG---PTDTAHFREVARI
MAV_3425|M.avium_104 -MSRRERGLTLNVNVLNLGIHTASWRRSAEPPTA---FTDPGYYVRMARI
TH_4079|M.thermoresistible__bu ---------LPETRLSG--------------------ITDIDHYLELARI
Mvan_6020|M.vanbaalenii_PYR-1 -------MMHLITWLMGNSYHAAGWRHQLAWERT---AMRLDVLIEIAKI
MAB_4125|M.abscessus_ATCC_1997 --MSSRNGRQLHLLAFGNVRAGGAWRLPGVRNGP---ANQLNTLVATAKA
MMAR_0703|M.marinum_M ------MIRKPVHLAAHFPGVNNTTVWADPGAGS---QIEFESFVHLART
Mflv_0250|M.gilvum_PYR-GCK MTDSAKRKAHLLGFVQHGVMNHASTMWAHPRDKVGYHWSRPEYWRDLGRT
Mb0978c|M.bovis_AF2122/97 ------MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPEHTHIPVKRQ
Rv0953c|M.tuberculosis_H37Rv ------MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPEHTHIPVKRQ
MUL_4507|M.ulcerans_Agy99 ------MALLFHWFLPTYGDSRGLVAGGHGLPMSGNRPATLRYLNQIAAA
MSMEG_2842|M.smegmatis_MC2_155 AERGLFDSLFLADSLALDGEAYRRPWRA---------CDPIVLFSALSQV
MAV_3425|M.avium_104 AERGTLDALFLADGPAVRDHPALRPSQA---------LEPSVILAAVAAE
TH_4079|M.thermoresistible__bu AERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTLVTALSTA
Mvan_6020|M.vanbaalenii_PYR-1 AEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTLMAAISQH
MAB_4125|M.abscessus_ATCC_1997 AEAAKFDAVFFADGLNFGPKATWAHKSTED-------FEPLTATSYLAAV
MMAR_0703|M.marinum_M AERGLFDFFFLAEGLRLREHRGRIHDLDVVGR-----PDTFTLLAALAGV
Mflv_0250|M.gilvum_PYR-GCK MERGLFDAMFIADELAPYTTYKGSSDPVVKFAGQCPVHEPASVVPIVGAF
Mb0978c|M.bovis_AF2122/97 AAHPTTGDASLPDDRYMRT------------------LDPWVSLGAASAV
Rv0953c|M.tuberculosis_H37Rv AAHPTTGDASLPDDRYMRT------------------LDPWVSLGAASAV
MUL_4507|M.ulcerans_Agy99 AESNGFEAVLTPAGLWCED--------------------AWLTTAMLVGT
. .
MSMEG_2842|M.smegmatis_MC2_155 TEHIGFIATVNA-LFAEPFTIARQIATLDHISGGRAGWNIVTSLNPAARA
MAV_3425|M.avium_104 TEHLGLIGTFSS-TFNDPVELAHRLLSLDQLSGGRLAWNIVTTYSEAAGG
TH_4079|M.thermoresistible__bu TTHIGLVATAST-TYTEPYGLARRFATLDHVSRGRAGWNIVTTANAAAAA
Mvan_6020|M.vanbaalenii_PYR-1 TKHIGLVGTAST-TYESPWVVARRFASLDHLSNGRASWNVVTGSNPGDSE
MAB_4125|M.abscessus_ATCC_1997 TERLGLVVTGSS-TFQPPYHLARQLLSLDHLSSGRAGWNLVTSFAQAAAA
MMAR_0703|M.marinum_M TDRIGLTGTINT-TFNEPFEVARQFATLDHLSEGRAGWNIVTSSDAFTGA
Mflv_0250|M.gilvum_PYR-GCK TKHLGIGITLST-SFVPPYMMARQLSTLDHLTGGRVGWNIVTSYSKSEFQ
Mb0978c|M.bovis_AF2122/97 TSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELV
Rv0953c|M.tuberculosis_H37Rv TSRIRLATAVALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELV
MUL_4507|M.ulcerans_Agy99 TKTLKFLVALRP-GLVSPTLAAQMATTFQQQSGGRLLVNVVTGGEAHEQR
* : : : * *: :::: : ** .:
MSMEG_2842|M.smegmatis_MC2_155 NFSKAAAIDPEDRYRKAEEAVRVVRSLWDSFEPDAVRADQRSGTYLDADK
MAV_3425|M.avium_104 NFGLADLPDRSTRYRRAAEFVDVALALWR-----------------DAAT
TH_4079|M.thermoresistible__bu NFGRPAHPDPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAPRFVDPDK
Mvan_6020|M.vanbaalenii_PYR-1 NFGLAHHPDRDSRYARAEEFVSACKALWNSWDEDAFVERKDTGQYLNARK
MAB_4125|M.abscessus_ATCC_1997 NFGERGFLPHDERYRLAEETLQVVKSLWHSLEPDTVIEDRAAGIYSDINK
MMAR_0703|M.marinum_M NFRRGGYLDHADRYQRAEEFLTVARKFWDSWAPGAVLADIENGDYVDPER
Mflv_0250|M.gilvum_PYR-GCK AMGKENLTPRDKRYEVVEEYMQLLYQLWDSWDDDAIVYDRDNGVFADPAK
Mb0978c|M.bovis_AF2122/97 DHG----VPPGRRRTMLREYLEAMRALWT---------------------
Rv0953c|M.tuberculosis_H37Rv DHG----VPPGRRRTMLREYLEAMRALWT---------------------
MUL_4507|M.ulcerans_Agy99 AYG--DFLDKQQRYRRTGEFLHVVRQLWAS--------------------
* * : :*
MSMEG_2842|M.smegmatis_MC2_155 VHAIDHTGDFFSVAGPGVVPQTPQ-GRPVIVQAGDSERLREMAGRWADAI
MAV_3425|M.avium_104 GGGVDHRGEFFAVTGSLPQGPSPQ-GHPLLVQAGGSPQGRELAGRVADAV
TH_4079|M.thermoresistible__bu IHAIDHRGEHFSVAGPLEVPRSPQ-GHPVLFQAGSSEPGKQLAAKYAEAI
Mvan_6020|M.vanbaalenii_PYR-1 VRVPDYKGRHLSVKGPLNVSRSPQ-GRPVLFHAGQSEGGRRLAARHADCI
MAB_4125|M.abscessus_ATCC_1997 IHVANHDGEFHKVKGPLGVTPSRQ-GHPVIFQAGSSTTGRAFAARHAEVV
MMAR_0703|M.marinum_M IRSVEHSGPQFEVRGFATLPAGPQ-GHPVLLQAGDSEQGRAFGARHADAM
Mflv_0250|M.gilvum_PYR-GCK VREVNFQGEFFQSRGRHFVAPSPQ-KRPVLWQAGSSAQGREFASRHAESV
Mb0978c|M.bovis_AF2122/97 QEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWIARSADGW
Rv0953c|M.tuberculosis_H37Rv QEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKWIARSADGW
MUL_4507|M.ulcerans_Agy99 GQPVTFEGEHIHVHQAQLGRLPDP--PPPVFFGGSSESAGAVAARYADTY
. * * : .. : .: *:
MSMEG_2842|M.smegmatis_MC2_155 FTVQRDIGSGRKFAQDAKHRARQHGRSPDELTILPGLFVVVGSTEAEALA
MAV_3425|M.avium_104 FSAELDLDAAIEHYRYVKDAAVAHGRGRDAVRILPGLITTIGSSRAEAQR
TH_4079|M.thermoresistible__bu FTAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGGTEEEARR
Mvan_6020|M.vanbaalenii_PYR-1 FEAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGRTESEAVE
MAB_4125|M.abscessus_ATCC_1997 FTGQTDVERAKNFYRQLHQEARAAGRTFAPL-VTPSLGVVVGSTEAEALA
MMAR_0703|M.marinum_M FTLHSSLRDGQRYYADVKGRARSYGRDPDQLKVFPAATFVIGDTPDQAGE
Mflv_0250|M.gilvum_PYR-GCK FGIFPTPKSMRAYATDIRTRASDAGRDPESVKLIYGLQTIIDRDKGRAND
Mb0978c|M.bovis_AF2122/97 ITTPRDVDID------------------EPVKLLQDIWAAAGRDG-----
Rv0953c|M.tuberculosis_H37Rv ITTPRDVDID------------------EPVKLLQDIWAAAGRDG-----
MUL_4507|M.ulcerans_Agy99 LTWGEPLSAVGKKIDWIRGLAADHGR---ALSYGLRIHVITRDTAEEAWR
: :
MSMEG_2842|M.smegmatis_MC2_155 RKAEI-DAFVDVEAERDQLAERIGADPRLLVLDKPVPTAILDAPTDSP--
MAV_3425|M.avium_104 RYEEQ-NALLPAGHDVERLSQTLGADLSGLPLDEPIPARLLGSVPDPSK-
TH_4079|M.thermoresistible__bu IQRRL-EDLTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSDDPPAIHM--
Mvan_6020|M.vanbaalenii_PYR-1 LYSEL-NSLISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS--APVVGG--
MAB_4125|M.abscessus_ATCC_1997 AESTI-YEHFIPEYQAGWLL-EVDVNVVGADLDGPVPASAFPDSTETH--
MMAR_0703|M.marinum_M KARQISYQQVSGATAIAMLEQVWGRDLSDYDPDGPLPDIDPIADAAISQG
Mflv_0250|M.gilvum_PYR-GCK RYAEF-VENVQIESALGILSGHTGFDFSTLGLDDNVVDADVQGIRGLFD-
Mb0978c|M.bovis_AF2122/97 ------------------LPQIVALDVKP---------------------
Rv0953c|M.tuberculosis_H37Rv ------------------LPQIVALDVKP---------------------
MUL_4507|M.ulcerans_Agy99 VADRLLAGIDPADIERMQANLARSESEGQRRMAELHG-------------
MSMEG_2842|M.smegmatis_MC2_155 ----SVSPAFAKALVTQSQTEGLTVRDLLT-RNPG-GHRYVVGSPESVAD
MAV_3425|M.avium_104 ---FVGSLGFRESVVRLVVSGGLTLRQTLR-AFSGSGHRVIVGSPVDVAD
TH_4079|M.thermoresistible__bu -------QSRYALVRRLVSTENLTVRELLLRLSGGRGHRVFAGTPEQVAD
Mvan_6020|M.vanbaalenii_PYR-1 -------NSIRGQLDAIAKAEQLTVRQMYERVVPTMGNTALIGTATQIAD
MAB_4125|M.abscessus_ATCC_1997 -------QTALAGYKHLATVGNPTVREFLYRTLNAFG-TRFVGSAEQVAD
MMAR_0703|M.marinum_M RVRHADPVAVARRYRERSQAENLSIRELVIAVTSR---QQFVGTPSHIAD
Mflv_0250|M.gilvum_PYR-GCK ------------AILEAKDGAPVTVREAAQIYGVSMGAPVAVGTPADVAD
Mb0978c|M.bovis_AF2122/97 -----------------------------------------------VPD
Rv0953c|M.tuberculosis_H37Rv -----------------------------------------------VPD
MUL_4507|M.ulcerans_Agy99 -----------GVLDQLEIAPNLWAGVGLVRGGAG---TALVGSHQEVAE
:.:
MSMEG_2842|M.smegmatis_MC2_155 DLELWFREGAADGFNLNIDRLPDGLAAFVDHVVPVLQERGLFRREYSTTT
MAV_3425|M.avium_104 TIEQWFGAGAADGFNLMPDVFPDGLEVFVDEVVPILRSRGLFRASYAEAT
TH_4079|M.thermoresistible__bu TIEEWFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRTEYTGTT
Mvan_6020|M.vanbaalenii_PYR-1 VMEEWYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRRHYTGST
MAB_4125|M.abscessus_ATCC_1997 QIELWFSEGAADGFILSTSGLPGQFELFTEHVVPILVRRGLFRAEYTGST
MMAR_0703|M.marinum_M EIDRYVQADACDGFILVPHLTPHGLDEFVDRVVPLLQERGAFRTAYTGQT
Mflv_0250|M.gilvum_PYR-GCK QMEQYLDEGDCNGFMMLATDTPGCFNDMTELLVPELQKRGRFRTRYPGTT
Mb0978c|M.bovis_AF2122/97 KLARWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV----------
Rv0953c|M.tuberculosis_H37Rv KLARWAELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV----------
MUL_4507|M.ulcerans_Agy99 RIIEYARLG-ISHFILSGYPHLEEAYWFGEGVLPILERKRLWHRPHGSSP
: : . . : : : . *
MSMEG_2842|M.smegmatis_MC2_155 LRGHLSS-----------------
MAV_3425|M.avium_104 LRERLTGD---------RHVVAA-
TH_4079|M.thermoresistible__bu LRDHLGLPRPRNRFTTGRPVAAAS
Mvan_6020|M.vanbaalenii_PYR-1 LRENLGLPPVDN-----SPFAT--
MAB_4125|M.abscessus_ATCC_1997 LREHLALPWPVP----ARPPALLA
MMAR_0703|M.marinum_M LRDHLGLAGLPS------------
Mflv_0250|M.gilvum_PYR-GCK LRESLREY----------------
Mb0978c|M.bovis_AF2122/97 ------------------------
Rv0953c|M.tuberculosis_H37Rv ------------------------
MUL_4507|M.ulcerans_Agy99 HSAALPVAHSSVN-----------