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VSSRNGRQLHLLAFGNVRAGGAWRLPGVRNGPANQLNTLVATAKAAEAAKFDAVFFADGLNFGPKATWAH KSTEDFEPLTATSYLAAVTERLGLVVTGSSTFQPPYHLARQLLSLDHLSSGRAGWNLVTSFAQAAAANFG ERGFLPHDERYRLAEETLQVVKSLWHSLEPDTVIEDRAAGIYSDINKIHVANHDGEFHKVKGPLGVTPSR QGHPVIFQAGSSTTGRAFAARHAEVVFTGQTDVERAKNFYRQLHQEARAAGRTFAPLVTPSLGVVVGSTE AEALAAESTIYEHFIPEYQAGWLLEVDVNVVGADLDGPVPASAFPDSTETHQTALAGYKHLATVGNPTVR EFLYRTLNAFGTRFVGSAEQVADQIELWFSEGAADGFILSTSGLPGQFELFTEHVVPILVRRGLFRAEYT GSTLREHLALPWPVPARPPALLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4125 | - | - | 100% (443) | putative nitrilotriacetate monooxygenase |
| M. abscessus ATCC 19977 | MAB_3401 | - | 1e-57 | 35.46% (423) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4232c | - | 5e-57 | 35.25% (451) | putative oxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 3e-07 | 23.40% (282) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0250 | - | 4e-51 | 33.25% (412) | hypothetical protein Mflv_0250 |
| M. tuberculosis H37Rv | Rv1855c | - | 3e-07 | 23.40% (282) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0703 | - | 1e-60 | 35.75% (442) | FMNH2-utilizing oxygenase |
| M. avium 104 | MAV_0340 | - | 8e-71 | 39.21% (454) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_4552 | ssuD | 1e-163 | 65.11% (427) | nitrilotriacetate monooxygenase component A |
| M. thermoresistible (build 8) | TH_4079 | - | 3e-80 | 41.99% (412) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 4e-09 | 24.28% (416) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 3e-68 | 36.55% (446) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1886c|M.bovis_AF2122/97 ------------MTIRLGLQIPNFSYGTGVEK-------LFPSVIAQARE
Rv1855c|M.tuberculosis_H37Rv ------------MTIRLGLQIPNFSYGTGVEK-------LFPSVIAQARE
MAB_4125|M.abscessus_ATCC_1997 ---MSSRNGRQLHLLAFGNVRAGGAWRLPGVR--NGPANQLNTLVATAKA
MSMEG_4552|M.smegmatis_MC2_155 ---MT----RELHLLAFGNTRSAGPWRHPAAD--NTPAGVRRRLIAYAQT
TH_4079|M.thermoresistible__bu ----------LPETRLSG-------------------ITDIDHYLELARI
Mvan_6020|M.vanbaalenii_PYR-1 --------MMHLITWLMGNSYHAAGWRHQLAW--ERTAMRLDVLIEIAKI
Mflv_0250|M.gilvum_PYR-GCK MTDSAKRKAHLLGFVQHGVMNHASTMWAHPRDKVGYHWSRPEYWRDLGRT
MAV_0340|M.avium_104 ---MRTDKMALVAFMQAGSTSVYAGSWRHPAN--EHRYLDAAYYAKIGRQ
MMAR_0703|M.marinum_M ---------MIRKPVHLAAHFPGVNNTTVWADPGAGSQIEFESFVHLART
MUL_4507|M.ulcerans_Agy99 ---MALLFHWFLPTYGDSRGLVAGGHGLPMSG---NRPATLRYLNQIAAA
. .
Mb1886c|M.bovis_AF2122/97 AEAAGYDSLFVMDHFYQLPMLGTPDQPM---------LEAYTALGALATA
Rv1855c|M.tuberculosis_H37Rv AEAAGYDSLFVMDHFYQLPMLGTPDQPM---------LEAYTALGALATA
MAB_4125|M.abscessus_ATCC_1997 AEAAKFDAVFFADGLNFGPKATWAHKSTED-------FEPLTATSYLAAV
MSMEG_4552|M.smegmatis_MC2_155 AEAGTFDALFFADGLNYGPPATWAYKITED-------FEPLTATAALSSV
TH_4079|M.thermoresistible__bu AERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTLVTALSTA
Mvan_6020|M.vanbaalenii_PYR-1 AEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTLMAAISQH
Mflv_0250|M.gilvum_PYR-GCK MERGLFDAMFIADELAPYTTYKGSSDPVVKFAGQCPVHEPASVVPIVGAF
MAV_0340|M.avium_104 LEEGCFDLMFFDDRLAMPGVYGGSVGEAVRYGARPVKLDLGVILGVLAQA
MMAR_0703|M.marinum_M AERGLFDFFFLAEGLRLREHRGRIHDLDVVG-----RPDTFTLLAALAGV
MUL_4507|M.ulcerans_Agy99 AESNGFEAVLTPAGLWCE--------------------DAWLTTAMLVGT
* : .: : :
Mb1886c|M.bovis_AF2122/97 TERLQLGALVTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHR
Rv1855c|M.tuberculosis_H37Rv TERLQLGALVTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHR
MAB_4125|M.abscessus_ATCC_1997 TERLGLVVTGS-STFQPPYHLARQLLSLDHLSSGRAGWNLVTSFAQAAAA
MSMEG_4552|M.smegmatis_MC2_155 TEHIGLVVTGS-ATLAHPYHLARQLLSLDHLSGGRAGWNLVTSFARAAAD
TH_4079|M.thermoresistible__bu TTHIGLVATAS-TTYTEPYGLARRFATLDHVSRGRAGWNIVTTANAAAAA
Mvan_6020|M.vanbaalenii_PYR-1 TKHIGLVGTAS-TTYESPWVVARRFASLDHLSNGRASWNVVTGSNPGDSE
Mflv_0250|M.gilvum_PYR-GCK TKHLGIGITLS-TSFVPPYMMARQLSTLDHLTGGRVGWNIVTSYSKSEFQ
MAV_0340|M.avium_104 TSRIGLGATYS-TTYYPPFHVARTFASLDHLSGGRAAWNVVTSVNDSEAQ
MMAR_0703|M.marinum_M TDRIGLTGTIN-TTFNEPFEVARQFATLDHLSEGRAGWNIVTSSDAFTGA
MUL_4507|M.ulcerans_Agy99 TKTLKFLVALR-PGLVSPTLAAQMATTFQQQSGGRLLVNVVTGGEAHEQR
* : : * *: ::: : ** .: :
Mb1886c|M.bovis_AF2122/97 QLG-FEFGTFSDRFNRLEEALQILEPMVKGERP-----------------
Rv1855c|M.tuberculosis_H37Rv QLG-FEFGTFSDRFNRLEEALQILEPMVKGERP-----------------
MAB_4125|M.abscessus_ATCC_1997 NFGERGFLPHDERYRLAEETLQVVKSLWHSLEPDTVIEDRAAGIYSDINK
MSMEG_4552|M.smegmatis_MC2_155 NFSARGVIDHDDRYAIAEEALEVVRKLWDEWGEDTIVEDRPAGIFNDVGR
TH_4079|M.thermoresistible__bu NFGRPAHPDPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAPRFVDPDK
Mvan_6020|M.vanbaalenii_PYR-1 NFGLAHHPDRDSRYARAEEFVSACKALWNSWDEDAFVERKDTGQYLNARK
Mflv_0250|M.gilvum_PYR-GCK AMGKENLTPRDKRYEVVEEYMQLLYQLWDSWDDDAIVYDRDNGVFADPAK
MAV_0340|M.avium_104 NFGVDAHLGHDERYDRADEFMDVVTGLWDTWEDDAVLHDRVSGRYADPAK
MMAR_0703|M.marinum_M NFRRGGYLDHADRYQRAEEFLTVARKFWDSWAPGAVLADIENGDYVDPER
MUL_4507|M.ulcerans_Agy99 AYG--DFLDKQQRYRRTGEFLHVVRQLWASGQP-----------------
*: * : :
Mb1886c|M.bovis_AF2122/97 ----TFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFADHLN
Rv1855c|M.tuberculosis_H37Rv ----TFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFADHLN
MAB_4125|M.abscessus_ATCC_1997 IHVANHDGEFHKVKGPLGVTPSRQGHPVIFQAGSSTTGRAFAARHAEVVF
MSMEG_4552|M.smegmatis_MC2_155 IRPANHHGRYFDVAGPIGAARSAQGQPVLFQAGSSETGRAFAARHAEVIF
TH_4079|M.thermoresistible__bu IHAIDHRGEHFSVAGPLEVPRSPQGHPVLFQAGSSEPGKQLAAKYAEAIF
Mvan_6020|M.vanbaalenii_PYR-1 VRVPDYKGRHLSVKGPLNVSRSPQGRPVLFHAGQSEGGRRLAARHADCIF
Mflv_0250|M.gilvum_PYR-GCK VREVNFQGEFFQSRGRHFVAPSPQKRPVLWQAGSSAQGREFASRHAESVF
MAV_0340|M.avium_104 VHELGHVGEFFSARGPLTVPRTPQGRPVIIQAGSSGRGREFASRWAELIF
MMAR_0703|M.marinum_M IRSVEHSGPQFEVRGFATLPAGPQGHPVLLQAGDSEQGRAFGARHADAMF
MUL_4507|M.ulcerans_Agy99 ---VTFEGEHIHVH-QAQLGRLPDPPPPVFFGGSSESAGAVAARYADTYL
. * : * : .* . ..:: *:
Mb1886c|M.bovis_AF2122/97 -IVAAVDELPRKMRALAARCDEAGRDRSTLQTSLLLTVMIDETLS-----
Rv1855c|M.tuberculosis_H37Rv -IVAAVDELPRKMRALAARCDEAGRDRSTLQTSLLLTVMIDETLS-----
MAB_4125|M.abscessus_ATCC_1997 TGQTDVERAKNFYRQLHQEARAAGRTFAPL-VTPSLGVVVGSTEAEALAA
MSMEG_4552|M.smegmatis_MC2_155 TSHGNRERAQTFYGQIHEQSRQFGRGAPPL-ITPSLRYIVGSTDEEARRA
TH_4079|M.thermoresistible__bu TAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGGTEEEARRI
Mvan_6020|M.vanbaalenii_PYR-1 EAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGRTESEAVEL
Mflv_0250|M.gilvum_PYR-GCK GIFPTPKSMRAYATDIRTRASDAGRDPESVKLIYGLQTIIDRDKGRANDR
MAV_0340|M.avium_104 TGDPGIDVARSHYADQKDRIADAGRDPAAVRICPMAYAVVGESEAHAKDR
MMAR_0703|M.marinum_M TLHSSLRDGQRYYADVKGRARSYGRDPDQLKVFPAATFVIGDTPDQAGEK
MUL_4507|M.ulcerans_Agy99 TWGEPLSAVGKKIDWIRGLAADHGR---ALSYGLRIHVITRDTAEEAWRV
* :
Mb1886c|M.bovis_AF2122/97 --------------------------------------------------
Rv1855c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4125|M.abscessus_ATCC_1997 EST-IYEHFIPEYQAGWLL-EVDVNVVGADLDGPVPASAFPDSTETHQTA
MSMEG_4552|M.smegmatis_MC2_155 ERE-EYEYFSPGYQAGWLL-EVDVDVTGADLDGPVPDSAFPEHTETHQTA
TH_4079|M.thermoresistible__bu QRR-LEDLTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSDDPPAIHMQSR
Mvan_6020|M.vanbaalenii_PYR-1 YSE-LNSLISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS--APVVGGNSI
Mflv_0250|M.gilvum_PYR-GCK YAEFVEN-VQIESALGILSGHTGFDFSTLGLDDNVVD----ADVQGIRGL
MAV_0340|M.avium_104 EAMLLNDLVHPMASLTLLSELMNYDFAQHDLDDPVTDDIL-ASVSGIRGL
MMAR_0703|M.marinum_M ARQISYQQVSGATAIAMLEQVWGRDLSDYDPDGPLPDIDPIADAAISQGR
MUL_4507|M.ulcerans_Agy99 ADR-------------LLAGIDPADIERMQANLARSESEGQRRMAELHGG
Mb1886c|M.bovis_AF2122/97 ------------------------PDAIPAEMSGRVVVGSPAQIADQIQA
Rv1855c|M.tuberculosis_H37Rv ------------------------PDAIPAEMSGRVVVGSPAQIADQIQA
MAB_4125|M.abscessus_ATCC_1997 LAGYKHLATVGNPTVR------EFLYRTLNAFG-TRFVGSAEQVADQIEL
MSMEG_4552|M.smegmatis_MC2_155 LAGYRHLASEGNPTVR------EFLYRTVNGWG-AAVVGTPERIADTIEE
TH_4079|M.thermoresistible__bu YALVRRLVSTENLTVR------ELLLRLSGGRGHRVFAGTPEQVADTIEE
Mvan_6020|M.vanbaalenii_PYR-1 RGQLDAIAKAEQLTVR------QMYERVVPTMGNTALIGTATQIADVMEE
Mflv_0250|M.gilvum_PYR-GCK FDAILEAKDGAPVTVR------EAAQIYGVSMGAPVAVGTPADVADQMEQ
MAV_0340|M.avium_104 VQNLRAHIGGDAVTVR------DLANHRATLLQGPRFVGTGPQVADQMAD
MMAR_0703|M.marinum_M VRHADPVAVARRYRERSQAENLSIRELVIAVTSRQQFVGTPSHIADEIDR
MUL_4507|M.ulcerans_Agy99 VLDQLEIAPNLWAGVG-----------LVRGGAGTALVGSHQEVAERIIE
*: :*: :
Mb1886c|M.bovis_AF2122/97 KVLDAGVDGLIIN--------------LAPHGYLPGVITT--AAEALRPL
Rv1855c|M.tuberculosis_H37Rv KVLDAGVDGLIIN--------------LAPHGYLPGVITT--AAEALRPL
MAB_4125|M.abscessus_ATCC_1997 WFSEGAADGFILSTSGLPGQFELFTEHVVPILVRRGLFRAEYTGSTLREH
MSMEG_4552|M.smegmatis_MC2_155 WFTTGAADGFVLRDSGLPGQHELFVEQVVPVLRKRGLFRHEYTGTTLRAH
TH_4079|M.thermoresistible__bu WFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRTEYTGTTLRDH
Mvan_6020|M.vanbaalenii_PYR-1 WYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRRHYTGSTLREN
Mflv_0250|M.gilvum_PYR-GCK YLDEGDCNGFMMLATDTPGCFNDMTELLVPELQKRGRFRTRYPGTTLRES
MAV_0340|M.avium_104 WFQTGACDGFVLAATHLPGAFEDVVRMVVPELQRRGLFRTEYRSATLRGH
MMAR_0703|M.marinum_M YVQADACDGFILVPHLTPHGLDEFVDRVVPLLQERGAFRTAYTGQTLRDH
MUL_4507|M.ulcerans_Agy99 YARLG-ISHFILSGYPHLEEAYWFGEGVLPILERKRLWHRPHGSSPHSAA
. : : : * . .
Mb1886c|M.bovis_AF2122/97 LGV------------------
Rv1855c|M.tuberculosis_H37Rv LGV------------------
MAB_4125|M.abscessus_ATCC_1997 LALPWPVPAR-----PPALLA
MSMEG_4552|M.smegmatis_MC2_155 LGL--DIPQR-----SVS---
TH_4079|M.thermoresistible__bu LGLP-RPRNRFTTGRPVAAAS
Mvan_6020|M.vanbaalenii_PYR-1 LGLP-PVDN-----SPFAT--
Mflv_0250|M.gilvum_PYR-GCK LREY-----------------
MAV_0340|M.avium_104 LGLPRPANAR------VAHA-
MMAR_0703|M.marinum_M LGLAGLPS-------------
MUL_4507|M.ulcerans_Agy99 LPVAHSSVN------------
*