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AVTASAGARPTGAQASSAAPGSAPRRRTRALFGTHPLHRTASALWRPLALVVVLLAAWWAVTETELVAPY ILPSPADTWLAAHDNAAYLAHNTWVTTWETVIGFVIAAIVGELVAVVMIYSAGVEKTVYPLILFAQVVPK IAIAPLFIVWLGFGPSPKILVAVLMAFFPIVISGLAGLRSVDPEILELTSTMGASRFKTFLKIRFPASLP QLMSGLKVAATLAVTGAVVGEFVGANEGLGYVILQANGNVDTAMLFAALIIMSLLGIALFAVIEFAEKLL IPWHSSRRTVGSATSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2635 | - | - | 100% (297) | ABC transporter permease protein |
| M. smegmatis MC2 155 | MSMEG_0487 | - | 3e-29 | 26.39% (269) | ABC transporter permease |
| M. smegmatis MC2 155 | MSMEG_4588 | - | 1e-27 | 27.27% (242) | ABC nitrate/sulfonate/bicarbonate family protein transporter, |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3783c | proW | 7e-10 | 26.62% (154) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_3159 | - | 3e-27 | 25.67% (261) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3757c | proW | 7e-10 | 26.62% (154) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 4e-09 | 26.35% (167) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_2216 | - | 5e-28 | 28.00% (275) | sulfonate ABC transporter, permease protein SsuC |
| M. marinum M | MMAR_5299 | proZ | 2e-13 | 24.31% (218) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. avium 104 | MAV_2433 | - | 7e-30 | 29.32% (266) | putative aliphatic sulfonates transport permease protein SsuC |
| M. thermoresistible (build 8) | TH_4654 | - | 6e-25 | 29.50% (261) | PUTATIVE putative binding-protein-dependent transport systems |
| M. ulcerans Agy99 | MUL_4374 | proZ | 2e-13 | 21.92% (219) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_3142 | - | 2e-33 | 33.47% (239) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3159|M.gilvum_PYR-GCK MTAVAAPLTTP--RGPAAPAPELVDVIAGHRGR-RSIWG-RIPRPVRRMA
TH_4654|M.thermoresistible__bu VTSLQTARPAPRLRSPAQRRADVTDAQLLHRGEHRTRLGPGRAVPAALAV
MAB_2216|M.abscessus_ATCC_1997 MTTRNTLVAAAATDSDAP-----------ESGPSRREWVLERRWEIVRFL
MAV_2433|M.avium_104 MSIATALDAAPKRLGGAA-----------SGAPGG--LWARRKWEVVRLV
MMAR_5299|M.marinum_M --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
Mb3783c|M.bovis_AF2122/97 --------------------------------------------------
Rv3757c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2635|M.smegmatis_MC2_155 MAVTASAGARPTGAQASSAAPGSAPRRRTRALFGTHPLHRTASALWRPLA
Mvan_3142|M.vanbaalenii_PYR-1 -----------------------------------MTARRIVSLAGPPMA
MLBr_02093|M.leprae_Br4923 --------MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALV
Mflv_3159|M.gilvum_PYR-GCK GPVAILAVWTIGSTSGLLNTD--LFPPPSDVAVT-AWHLLTNGGLALHVG
TH_4654|M.thermoresistible__bu GPLLLVALWLITSQLGILDPR--TLPHPFDIART-AAELWSDGRLPANVA
MAB_2216|M.abscessus_ATCC_1997 SPLAVLLIWQAGSAWGLIDPD--ILPAPSTIARA-GFELIANGQLAEALR
MAV_2433|M.avium_104 SPLALLALWQLGSAIGVIAQD--VLPAPSLILQA-GVELTRNGQLADALH
MMAR_5299|M.marinum_M -------------------MN--FLQQALSYLST-AANWTGSAGLAHRTA
MUL_4374|M.ulcerans_Agy99 -------------------MN--FLQQALSYLST-AANWTGSAGLAHRTA
Mb3783c|M.bovis_AF2122/97 -------------------MH--YLMTHP------GAAWA-------LTV
Rv3757c|M.tuberculosis_H37Rv -------------------MH--YLMTHP------GAAWA-------LTV
MSMEG_2635|M.smegmatis_MC2_155 LVVVLLAAWWAVTETELVAPY--ILPSPADTWLA-AHDNAAY--LAHNTW
Mvan_3142|M.vanbaalenii_PYR-1 LLAVVIVAWYAVSYLVLDSSEKFLLPPPHDVVAQGLLDADTRDDITSALW
MLBr_02093|M.leprae_Br4923 PLVWLLSVVVARGFYAVTRFD--WWTHSLRGVMPEEFAGGVYHALYGSLV
Mflv_3159|M.gilvum_PYR-GCK TSATRVLIGTALGITVGVVLAVLAG--LTRTGEDLLDWSMQILKAVPNFA
TH_4654|M.thermoresistible__bu ASLKLSLISLAIGVAAGLALALLAG--LSRIGEALVDGPIQIKRAVPTLA
MAB_2216|M.abscessus_ATCC_1997 VSGVRAAEGLLLGGVIGVVLGAAVG--LSRLADAVVDPTMQMIRALPHLG
MAV_2433|M.avium_104 ISTVRVIEGLALGGVIGIVAGAAVG--LSRWVEATVDPPLQMIRALPHLG
MMAR_5299|M.marinum_M EHLEYTALAVTASALVAIPIGLIIG--HTGRGQLLVVSAVNGLRALPTLG
MUL_4374|M.ulcerans_Agy99 EHLEYTALAATASALVAIPIGLIIG--HTGRGQLLVVSAVNGLRALPTLG
Mb3783c|M.bovis_AF2122/97 VHLRLSLLPVLIGLMSAVPLGLLVQ--RAPLLRRLTTATASVIFTIPSLA
Rv3757c|M.tuberculosis_H37Rv VHLRLSLLPVLIGLMSAVPLGLLVQ--RAPLLRRLTTATASVIFTIPSLA
MSMEG_2635|M.smegmatis_MC2_155 VTTWETVIGFVIAAIVGELVAVVMI--YSAGVEKTVYPLILFAQVVPKIA
Mvan_3142|M.vanbaalenii_PYR-1 VSAKVAIIGLVAAIVIGGVLAVAMA--QAKWVERSLYPWVILLQTVPILA
MLBr_02093|M.leprae_Br4923 QAVVAAIMAVPLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALF
. . :. :
Mflv_3159|M.gilvum_PYR-GCK LTPLLIIWMG---IGEGPKIVLITMGVAIAVYINTYSGIRGVDQQLVEMA
TH_4654|M.thermoresistible__bu IIPLAIIWFG---IGDTMKIVIIATSVLIPVYINTTAQLKGVDLRHVELA
MAB_2216|M.abscessus_ATCC_1997 LIPLFIVWFG---IGELPKVLMVALGAAFPLYLNTTSAIRQVDPKLFETA
MAV_2433|M.avium_104 LIPLFILWFG---IGELPKVLLVALGVVFPLYLNTFSAIRQVDPKMLETA
MMAR_5299|M.marinum_M VLLLGVLLFG---LGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAA
MUL_4374|M.ulcerans_Agy99 VLLLGVLLFG---LGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAA
Mb3783c|M.bovis_AF2122/97 LFVVLPLIIGTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAA
Rv3757c|M.tuberculosis_H37Rv LFVVLPLIIGTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAA
MSMEG_2635|M.smegmatis_MC2_155 IAPLFIVWLG---FGPSPKILVAVLMAFFPIVISGLAGLRSVDPEILELT
Mvan_3142|M.vanbaalenii_PYR-1 IVPVIGFWFG---FELFARVLVVVIIALFPLIINPLQGLLGADRGLHDLF
MLBr_02093|M.leprae_Br4923 IFCLWIATLG-FQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREAC
: : :* : : : . :
Mflv_3159|M.gilvum_PYR-GCK QTLEARRGTLITQVILPGAMPNFLVGLRLGLSSAWLSLIFAEMINTTE--
TH_4654|M.thermoresistible__bu QTVGLSRVQFIRKVALPGALPGFFTGLRLAVTISWTALVVVEQVNATS--
MAB_2216|M.abscessus_ATCC_1997 QVLGFSFWQRLRVIVIPGATPQVLVGLRQSLALSWLTLIVAEQINADA--
MAV_2433|M.avium_104 QVLGFSFFQRFRRILVPGTAPQVLVGLRQSLAIAWLTLIVAEQINADK--
MMAR_5299|M.marinum_M RAMGMTEAQVVLRVEMPNALPLILGGLR-SATLQVVATATVAAYASLG--
MUL_4374|M.ulcerans_Agy99 RAMGMTEAQVVLRVEMPNALPLILGGLR-SATLQVVATVTVAAYASLG--
Mb3783c|M.bovis_AF2122/97 TAIGYSRIAQMLKVELPLSIPVLVAGLR-VVAVTNIAMVSVGSVIGIG--
Rv3757c|M.tuberculosis_H37Rv TAIGYSRIAQMLKVELPLSIPVLVAGLR-VVAVTNIAMVSVGSVIGIG--
MSMEG_2635|M.smegmatis_MC2_155 STMGASRFKTFLKIRFPASLPQLMSGLKVAATLAVTGAVVGEFVGANE--
Mvan_3142|M.vanbaalenii_PYR-1 TLTGARPLTRLLKLQIPSAMPDVFVGLQSAAGLAVVGATVGDYFFGRGQI
MLBr_02093|M.leprae_Br4923 YALGIPKWKTIVRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSR-
. : .* : * .. *:
Mflv_3159|M.gilvum_PYR-GCK GIGFLMSRAQTNLQFDVSLLVIVIYAVLGLASYALVRLLERLLLS-----
TH_4654|M.thermoresistible__bu GVGFLMTQARLYGQLEVVVVGLVVYAVFGLAGDHLVRTIERRALS-----
MAB_2216|M.abscessus_ATCC_1997 GVGFLINNARDFLRIDVIIFGLVVYALLGIVTDAIVRVLERRALR-----
MAV_2433|M.avium_104 GIGFLINNARDFLRIDIIIFGLTIYALLGIITDAVVRLIERRAVR-----
MMAR_5299|M.marinum_M GLGRYLIDGIKERQFHIALVGALMVAALALSLDGLLALAGWASVPGTGRL
MUL_4374|M.ulcerans_Agy99 GLGRYLIDGIKERQSHIALVGALMVAALALSLDGLLALAGWASVPGTGRV
Mb3783c|M.bovis_AF2122/97 GLGTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATP----W
Rv3757c|M.tuberculosis_H37Rv GLGTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATP----W
MSMEG_2635|M.smegmatis_MC2_155 GLGYVILQANGNVDTAMLFAALIIMSLLGIALFAVIEFAEKLLIP-----
Mvan_3142|M.vanbaalenii_PYR-1 GLGMLLARYSSRLQSAEMLATVLTACLLGVVAFWIFGALGRRIVG-----
MLBr_02093|M.leprae_Br4923 SINFDIFDGNMASLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLF
.:. : ..
Mflv_3159|M.gilvum_PYR-GCK ---WRNGFAGFEATA-------------
TH_4654|M.thermoresistible__bu ---WRRALGG------------------
MAB_2216|M.abscessus_ATCC_1997 ---YRS----------------------
MAV_2433|M.avium_104 ---YRH----------------------
MMAR_5299|M.marinum_M SRFWHQSDDRIDVAVSPNSAAVGSHVLR
MUL_4374|M.ulcerans_Agy99 SRFWHQPDDRIDVAVSANSAAVGSHVLR
Mb3783c|M.bovis_AF2122/97 ERAPRAARRRRQVAAPITGGAR------
Rv3757c|M.tuberculosis_H37Rv ERAPRAARRRRQVAAPITGGAR------
MSMEG_2635|M.smegmatis_MC2_155 ---WHSSRRTVGSATSA-----------
Mvan_3142|M.vanbaalenii_PYR-1 --RWSPAWGAR-----------------
MLBr_02093|M.leprae_Br4923 GAAFRFLATRRCSGCR------------