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TAVAAPLTTPRGPAAPAPELVDVIAGHRGRRSIWGRIPRPVRRMAGPVAILAVWTIGSTSGLLNTDLFPP PSDVAVTAWHLLTNGGLALHVGTSATRVLIGTALGITVGVVLAVLAGLTRTGEDLLDWSMQILKAVPNFA LTPLLIIWMGIGEGPKIVLITMGVAIAVYINTYSGIRGVDQQLVEMAQTLEARRGTLITQVILPGAMPNF LVGLRLGLSSAWLSLIFAEMINTTEGIGFLMSRAQTNLQFDVSLLVIVIYAVLGLASYALVRLLERLLLS WRNGFAGFEATA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3159 | - | - | 100% (293) | binding-protein-dependent transport systems inner membrane component |
| M. gilvum PYR-GCK | Mflv_0724 | - | 4e-29 | 30.34% (267) | binding-protein-dependent transport systems inner membrane |
| M. gilvum PYR-GCK | Mflv_3108 | - | 3e-09 | 25.64% (195) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 1e-10 | 24.61% (191) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. tuberculosis H37Rv | Rv3756c | proZ | 1e-10 | 24.61% (191) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2216 | - | 2e-53 | 41.91% (241) | sulfonate ABC transporter, permease protein SsuC |
| M. marinum M | MMAR_5299 | proZ | 2e-11 | 27.37% (179) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. avium 104 | MAV_2433 | - | 2e-52 | 40.64% (251) | putative aliphatic sulfonates transport permease protein SsuC |
| M. smegmatis MC2 155 | MSMEG_5530 | - | 1e-128 | 81.72% (279) | putative aliphatic sulfonates transport permease protein SsuC |
| M. thermoresistible (build 8) | TH_4654 | - | 2e-58 | 42.66% (286) | PUTATIVE putative binding-protein-dependent transport systems |
| M. ulcerans Agy99 | MUL_4374 | proZ | 4e-10 | 24.00% (200) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. vanbaalenii PYR-1 | Mvan_3413 | - | 1e-53 | 41.22% (279) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3159|M.gilvum_PYR-GCK --MTAVAAPLTTPRGPAAPAPELVDVIAGHRGRR--SIWGRIPRPVRRMA
MSMEG_5530|M.smegmatis_MC2_155 --MGRGQVMTATAVAPEAAGPDLVDITAIHIRRK--SLWALIPRPLRRLM
MAV_2433|M.avium_104 ---------MSIATALDAAPKRLGGAASGAPGG----LWARRKWEVVRLV
Mvan_3413|M.vanbaalenii_PYR-1 ---------MTRPADPTAP---LAQANSGRVG-----RRADRRWALIRLA
MAB_2216|M.abscessus_ATCC_1997 ---------MTTRNTLVAAAATDSDAPESGPSRR--EWVLERRWEIVRFL
TH_4654|M.thermoresistible__bu VTSLQTARPAPRLRSPAQRRADVTDAQLLHRGEHRTRLGPGRAVPAALAV
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5299|M.marinum_M --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3159|M.gilvum_PYR-GCK GPVAILAVWTIGSTSGLLNTDLFPPPSDVAVTAWHLLTNGGLALHVGTSA
MSMEG_5530|M.smegmatis_MC2_155 GPALILLAWTVGSGTGLLNTDLFPPPTDVAATAWRLFDNGQLATHIGASA
MAV_2433|M.avium_104 SPLALLALWQLGSAIGVIAQDVLPAPSLILQAGVELTRNGQLADALHIST
Mvan_3413|M.vanbaalenii_PYR-1 SPFILLAVWQLGSAVGLIPQDVLPAPSLIAEAGIELIGNGQLVDALTVSG
MAB_2216|M.abscessus_ATCC_1997 SPLAVLLIWQAGSAWGLIDPDILPAPSTIARAGFELIANGQLAEALRVSG
TH_4654|M.thermoresistible__bu GPLLLVALWLITSQLGILDPRTLPHPFDIARTAAELWSDGRLPANVAASL
Mb3782c|M.bovis_AF2122/97 -------------------MNFLQQALSYLLTASNWTGPVGLAVRTCEHL
Rv3756c|M.tuberculosis_H37Rv -------------------MNFLQQALSYLLTASNWTGPVGLAVRTCEHL
MMAR_5299|M.marinum_M -------------------MNFLQQALSYLSTAANWTGSAGLAHRTAEHL
MUL_4374|M.ulcerans_Agy99 -------------------MNFLQQALSYLSTAANWTGSAGLAHRTAEHL
: . :. . *
Mflv_3159|M.gilvum_PYR-GCK TRVLIGTALGITVGVVLAVLAGLTRTGEDLLDWSMQILKAVPNFALTPLL
MSMEG_5530|M.smegmatis_MC2_155 VRVLVGTVLGILIGVVLAVLAGLTRTGEDLLDWTMQILKAVPNFALTPLL
MAV_2433|M.avium_104 VRVIEGLALGGVIGIVAGAAVGLSRWVEATVDPPLQMIRALPHLGLIPLF
Mvan_3413|M.vanbaalenii_PYR-1 LRVVEGLILGGVIGIALGTAVGLSKWFEATVDPPMQMVRALPHLGLIPLF
MAB_2216|M.abscessus_ATCC_1997 VRAAEGLLLGGVIGVVLGAAVGLSRLADAVVDPTMQMIRALPHLGLIPLF
TH_4654|M.thermoresistible__bu KLSLISLAIGVAAGLALALLAGLSRIGEALVDGPIQIKRAVPTLAIIPLA
Mb3782c|M.bovis_AF2122/97 EYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRALPTLGVLLLG
Rv3756c|M.tuberculosis_H37Rv EYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRALPTLGVLLLG
MMAR_5299|M.marinum_M EYTALAVTASALVAIPIGLIIGHTGRGQLLVVSAVNGLRALPTLGVLLLG
MUL_4374|M.ulcerans_Agy99 EYTALAATASALVAIPIGLIIGHTGRGQLLVVSAVNGLRALPTLGVLLLG
. . .: . * : : .:: :*:* :.: *
Mflv_3159|M.gilvum_PYR-GCK IIWMGIGEGPKIVLITMGVAIAVYINTYSGIRGVDQQLVEMAQTLEARRG
MSMEG_5530|M.smegmatis_MC2_155 IIWMGIGEGPKIVLITTGVAIAIYINTYSGIRGVDRQLVEMAQTLEAPRR
MAV_2433|M.avium_104 ILWFGIGELPKVLLVALGVVFPLYLNTFSAIRQVDPKMLETAQVLGFSFF
Mvan_3413|M.vanbaalenii_PYR-1 IIWFGIGELPKVLLVALGVSFPLYLNTFSAIRQVDPKLFETAQVLGFSFW
MAB_2216|M.abscessus_ATCC_1997 IVWFGIGELPKVLMVALGAAFPLYLNTTSAIRQVDPKLFETAQVLGFSFW
TH_4654|M.thermoresistible__bu IIWFGIGDTMKIVIIATSVLIPVYINTTAQLKGVDLRHVELAQTVGLSRV
Mb3782c|M.bovis_AF2122/97 VLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTES
Rv3756c|M.tuberculosis_H37Rv VLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTES
MMAR_5299|M.marinum_M VLLFGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEA
MUL_4374|M.ulcerans_Agy99 VLLFGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEA
:: :*:* :: : .: .* : : ** .: *:.:
Mflv_3159|M.gilvum_PYR-GCK TLITQVILPGAMPNFLVGLRLGLSSAWLSLIFAEMINTTEGIGFLMSRAQ
MSMEG_5530|M.smegmatis_MC2_155 TLITQVILPGAMPNFLVGLRLGLSSAWLSLIFAEMINTTEGIGFLMSRAQ
MAV_2433|M.avium_104 QRFRRILVPGTAPQVLVGLRQSLAIAWLTLIVAEQINADKGIGFLINNAR
Mvan_3413|M.vanbaalenii_PYR-1 QRFRSIIVPSAAPQVLVGLRQSLAIAWLTLIVAEQINADKGIGFLIMNAR
MAB_2216|M.abscessus_ATCC_1997 QRLRVIVIPGATPQVLVGLRQSLALSWLTLIVAEQINADAGVGFLINNAR
TH_4654|M.thermoresistible__bu QFIRKVALPGALPGFFTGLRLAVTISWTALVVVEQVNATSGVGFLMTQAR
Mb3782c|M.bovis_AF2122/97 QVLLRVEVPNALPLMLGGLRS-ATLQVVATATVAAYASLGGLGGYLIDGI
Rv3756c|M.tuberculosis_H37Rv QVLLRVEVPNALPLMLGGLRS-ATLQVVATATVAAYASLGGLGGYLIDGI
MMAR_5299|M.marinum_M QVVLRVEMPNALPLILGGLRS-ATLQVVATATVAAYASLGGLGRYLIDGI
MUL_4374|M.ulcerans_Agy99 QVVLRVEMPNALPLILGGLRS-ATLQVVATVTVAAYASLGGLGRYLIDGI
. : :*.: * .: *** : : . : *:* : .
Mflv_3159|M.gilvum_PYR-GCK TNLQFDVSLLVIVIYAVLGLASYALVRLLERLLLSWRNGFAGFEATA---
MSMEG_5530|M.smegmatis_MC2_155 TNLQFDVSLLVIVIYAIAGLLSYSLVRLLERLLLSWRNGFDGVS------
MAV_2433|M.avium_104 DFLRIDIIIFGLTIYALLGIITDAVVRLIERRAVRYRH------------
Mvan_3413|M.vanbaalenii_PYR-1 DFLRIDIIIFGLIVYALLGIGTDAVVRALERRALRYRS------------
MAB_2216|M.abscessus_ATCC_1997 DFLRIDVIIFGLVVYALLGIVTDAIVRVLERRALRYRS------------
TH_4654|M.thermoresistible__bu LYGQLEVVVVGLVVYAVFGLAGDHLVRTIERRALSWRRALGG--------
Mb3782c|M.bovis_AF2122/97 KERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL-------
Rv3756c|M.tuberculosis_H37Rv KERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL-------
MMAR_5299|M.marinum_M KERQFHIALVGALMVAALALSLDGLLALAGWASVPGTGRLSRFWHQSDDR
MUL_4374|M.ulcerans_Agy99 KERQSHIALVGALMVAALALSLDGLLALAGWASVPGTGRVSRFWHQPDDR
: .: :. : * .: :: :
Mflv_3159|M.gilvum_PYR-GCK ------------------
MSMEG_5530|M.smegmatis_MC2_155 ------------------
MAV_2433|M.avium_104 ------------------
Mvan_3413|M.vanbaalenii_PYR-1 ------------------
MAB_2216|M.abscessus_ATCC_1997 ------------------
TH_4654|M.thermoresistible__bu ------------------
Mb3782c|M.bovis_AF2122/97 --AAVVDKPAAGGGHALR
Rv3756c|M.tuberculosis_H37Rv --AAVVDKPAAGGGHALR
MMAR_5299|M.marinum_M IDVAVSPNSAAVGSHVLR
MUL_4374|M.ulcerans_Agy99 IDVAVSANSAAVGSHVLR