For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NFLQQALSYLSTAANWTGSAGLAHRTAEHLEYTALAVTASALVAIPIGLIIGHTGRGQLLVVSAVNGLRA LPTLGVLLLGVLLFGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMTEAQVVLRVEMPN ALPLILGGLRSATLQVVATATVAAYASLGGLGRYLIDGIKERQFHIALVGALMVAALALSLDGLLALAGW ASVPGTGRLSRFWHQSDDRIDVAVSPNSAAVGSHVLR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5299 | proZ | - | 100% (248) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProZ |
M. marinum M | MMAR_0033 | - | 5e-31 | 37.57% (189) | hypothetical protein MMAR_0033 |
M. marinum M | MMAR_0035 | - | 2e-17 | 30.93% (194) | ABC transporter permease |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3782c | proZ | 1e-107 | 80.65% (248) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
M. gilvum PYR-GCK | Mflv_1210 | - | 6e-94 | 72.18% (248) | binding-protein-dependent transport systems inner membrane |
M. tuberculosis H37Rv | Rv3756c | proZ | 1e-107 | 80.65% (248) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0264 | - | 4e-90 | 75.91% (220) | osmoprotectant ABC transporter ProZ |
M. avium 104 | MAV_0320 | - | 5e-99 | 78.79% (231) | ABC transporter, permease protein |
M. smegmatis MC2 155 | MSMEG_6331 | - | 2e-91 | 75.45% (220) | ABC transporter, permease protein ProZ |
M. thermoresistible (build 8) | TH_3904 | - | 5e-32 | 36.51% (189) | PUTATIVE conserved hypothetical membrane protein |
M. ulcerans Agy99 | MUL_4374 | proZ | 1e-131 | 97.58% (248) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
M. vanbaalenii PYR-1 | Mvan_5598 | - | 1e-89 | 74.32% (222) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_5299|M.marinum_M ------------------------------------------MNFLQQAL MUL_4374|M.ulcerans_Agy99 ------------------------------------------MNFLQQAL Mb3782c|M.bovis_AF2122/97 ------------------------------------------MNFLQQAL Rv3756c|M.tuberculosis_H37Rv ------------------------------------------MNFLQQAL MAV_0320|M.avium_104 ------------------------------------------MNFVQRAI Mflv_1210|M.gilvum_PYR-GCK ------------------------------------------MNFLQEAL Mvan_5598|M.vanbaalenii_PYR-1 ------------------------------------------MNFLQEAL MSMEG_6331|M.smegmatis_MC2_155 ------------------------------------------MNFLQQAL MAB_0264|M.abscessus_ATCC_1997 ------------------------------------------MNFLSNAL TH_3904|M.thermoresistible__bu VTATVDDTGDTGHTGCTGTAGDRASRSAARRWARRTVQPVLCLVAVGGAL : : *: MMAR_5299|M.marinum_M SYLSTAAN------WTGSAGLAHRTAEHLEYTALAVTASALVAIPIGLII MUL_4374|M.ulcerans_Agy99 SYLSTAAN------WTGSAGLAHRTAEHLEYTALAATASALVAIPIGLII Mb3782c|M.bovis_AF2122/97 SYLLTASN------WTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLI Rv3756c|M.tuberculosis_H37Rv SYLLTASN------WTGPVGLAVRTCEHLEYTAVAVAASALIAVPVGLLI MAV_0320|M.avium_104 AYLLSADN------WTGPVGLAARILEHLEYTGIAVGASALIAVPVGLLI Mflv_1210|M.gilvum_PYR-GCK SFIFTAAN------WAGPAGLTARILEHLQYTVIAVFFSALIAVPLGMLI Mvan_5598|M.vanbaalenii_PYR-1 SFIFTAAN------WGGPAGLSARILEHLQYTVIAVFFSAVIAVPLGMLI MSMEG_6331|M.smegmatis_MC2_155 AFIFTAEN------WAGPSGLGARIVEHLEYTAVAVFFSALIAVPLGMVI MAB_0264|M.abscessus_ATCC_1997 GYIFTASH------WAGSSGLGVRIGEHLEYTALAVLAAVVIAVPLGLFI TH_3904|M.thermoresistible__bu AYVHLADVSESEKRSLGVPHLLMLLRQHMEISLAATVLTCAIAIPLGVAL .:: * * * :*:: : *. : :*:*:*: : MMAR_5299|M.marinum_M G--HTGRGQLLVVSAVNGLRALPTLGVLLLGVLLFGLGLGPPIVALMLLG MUL_4374|M.ulcerans_Agy99 G--HTGRGQLLVVSAVNGLRALPTLGVLLLGVLLFGLGLGPPIVALMLLG Mb3782c|M.bovis_AF2122/97 G--HTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLGPPLVALMLLG Rv3756c|M.tuberculosis_H37Rv G--HTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLGPPLVALMLLG MAV_0320|M.avium_104 G--HTGRGTLLVVGAVNGLRALPTLGVLLFGTLLFGLGLGPSLVALMLLG Mflv_1210|M.gilvum_PYR-GCK G--HTGRGTFVVVTGVNALRALPTLGVLLLGVLLWGLGLIPPTVALMLLG Mvan_5598|M.vanbaalenii_PYR-1 G--HTGRGTFVVVTGVNALRALPTLGVLLLGVLLWGLGLIPPTVALMLLG MSMEG_6331|M.smegmatis_MC2_155 G--HTGRGTFLVVTGVNALRALPTLGVLLLGVLLWGLGLVPPTVALMLLG MAB_0264|M.abscessus_ATCC_1997 G--HTGRGIFLVVSAVNALRALPTLGMLLLGVLLWGLGLVPPTVALLLLG TH_3904|M.thermoresistible__bu TRGRFRRFATPIITVSGFGQAAPAIGLIALGAVLFGIGAVGAVAALTVYG : * :: . :* *::*:: :*.:*:*:* . .** : * MMAR_5299|M.marinum_M MPPLLAGTYAGIASVDPLVVDAARAMGMTEAQVVLRVEMPNALPLILGGL MUL_4374|M.ulcerans_Agy99 MPPLLAGTYAGIASVDPLVVDAARAMGMTEAQVVLRVEMPNALPLILGGL Mb3782c|M.bovis_AF2122/97 IPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNALPLMLGGL Rv3756c|M.tuberculosis_H37Rv IPSLLASTYAGIASVDPLVVDAARAMGMTESQVLLRVEVPNALPLMLGGL MAV_0320|M.avium_104 VPALLAGTYAGIANVEPTVVDAARAMGMTESQVLLRVEVPNALPLILGGL Mflv_1210|M.gilvum_PYR-GCK IPPLLAGTYSGIANVDRSVVDAARSMGMTESRILLRVETPNALPLILGGL Mvan_5598|M.vanbaalenii_PYR-1 IPPLLAGTYSGIANVDRDVVDAARAMGMTESRILLRVETPIAMPLILGGL MSMEG_6331|M.smegmatis_MC2_155 IPPLLAGTYAGVANVERTVVDAARSMGMTESRILLRVEVPNALPLILGGL MAB_0264|M.abscessus_ATCC_1997 VPPLLAGTYSGIANVDRTVVEAARAMGMTERQVLFGVEVPNALPLILSGL TH_3904|M.thermoresistible__bu ALPIIANTVTGLNGVDDRLIEAARGMGMPTSTTLLRVELPLALPVIIAGV .::*.* :*: .*: :::***.***. :: ** * *:*:::.*: MMAR_5299|M.marinum_M RSATLQVVATATVAAYASLGGLGRYLIDGIKERQFHIALVGALMVAALAL MUL_4374|M.ulcerans_Agy99 RSATLQVVATVTVAAYASLGGLGRYLIDGIKERQSHIALVGALMVAALAL Mb3782c|M.bovis_AF2122/97 RSATLQVVATATVAAYASLGGLGGYLIDGIKERRFHIALVGAMMVAALAL Rv3756c|M.tuberculosis_H37Rv RSATLQVVATATVAAYASLGGLGGYLIDGIKERRFHIALVGAMMVAALAL MAV_0320|M.avium_104 RSATLQVVATATVAAYASLGGLGRYLIDGIKEREFHLALVGALTVAALAL Mflv_1210|M.gilvum_PYR-GCK RTATLQIVATATVAAYASLGGLGRYLIDGIKVREFYLALVGALMVTALAL Mvan_5598|M.vanbaalenii_PYR-1 RTATLQIVATATVAAYASLGGLGRYLIDGIKVREFYLALVGALMVTALAL MSMEG_6331|M.smegmatis_MC2_155 RTSTLQIVATATVAAYASLGGLGRYLIDGIKIREFHIALVGAIMVTALAL MAB_0264|M.abscessus_ATCC_1997 RTATLQVVATATVAAYASLGGLGRYLIDGIKVRQFHLALVGAIMVTALAL TH_3904|M.thermoresistible__bu RTALVLIVGTAALASFTGAGGLGQLITTGIKLQQTVTLIVGAVLVAALAL *:: : :*.*.::*:::. **** : *** :. :***: *:**** MMAR_5299|M.marinum_M SLDGLLALAGWASVPGTGRLSRFWH------QSDDRIDVAVSPNSAAVGS MUL_4374|M.ulcerans_Agy99 SLDGLLALAGWASVPGTGRVSRFWH------QPDDRIDVAVSANSAAVGS Mb3782c|M.bovis_AF2122/97 TLDGLLALAGWVSVPGTGRMRKL---------------AAVVDKPAAGGG Rv3756c|M.tuberculosis_H37Rv TLDGLLALAGWVSVPGTGRMRKL---------------AAVVDKPAAGGG MAV_0320|M.avium_104 VLDGLLAVAVWASVPGTGRLRRT---------------YRPLPHRLAGTS Mflv_1210|M.gilvum_PYR-GCK ILDALLAFAVWASVPGTGRLSRRRA----MPQPFLDDEVALESGSPAVRS Mvan_5598|M.vanbaalenii_PYR-1 ILDAALAFAVWASVPGSGRLHRSGS----MPQPLLGDEVALESRSRAGRR MSMEG_6331|M.smegmatis_MC2_155 ILDAALAFAVWLSVPGAGRLRGRRSGRGQMPQPFLGDEVALESRTPNASA MAB_0264|M.abscessus_ATCC_1997 LLDAVLALAVWLSAPGTGRLRPVPD------LPDREGHAVYADSGVSAGA TH_3904|M.thermoresistible__bu FIDWLARMVEVVAAPKGL-------------------------------- :* .. :.* MMAR_5299|M.marinum_M HVLR-------------- MUL_4374|M.ulcerans_Agy99 HVLR-------------- Mb3782c|M.bovis_AF2122/97 HALR-------------- Rv3756c|M.tuberculosis_H37Rv HALR-------------- MAV_0320|M.avium_104 YGR--------------- Mflv_1210|M.gilvum_PYR-GCK PVTNGGSRRIR------- Mvan_5598|M.vanbaalenii_PYR-1 PDSEARHERGNPSPTVEA MSMEG_6331|M.smegmatis_MC2_155 RSSGVGYEGGAPSHTVEG MAB_0264|M.abscessus_ATCC_1997 MPRSPG------------ TH_3904|M.thermoresistible__bu ------------------