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STDGSTTSNRRATDDIFTKVTPGRASEMILDQIRSLIRDGHLKPGDRLPSERELGDRFGVSRVTVREALR GLEANAMVTIKVGAHGGAFVTAPTSSRVSEGIVDLLSMSGLTDIEITEARQVFELGIIPLVCERATEADI EELLQICDRGDAAAGQGSSSMELSAQFHTRVAEASHNAALAMLAEAFYGPTLVSLRHVQEGHPEIGVRSS REHRQFVMAVKKGDVEKATAVMRTHLGRTARHVKG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2605 | - | - | 100% (246) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_4121 | - | 4e-27 | 32.44% (225) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5201 | - | 3e-24 | 31.98% (222) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0601 | - | 2e-11 | 27.78% (216) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2114 | - | 5e-23 | 32.31% (229) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0586 | - | 2e-11 | 27.78% (216) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 6e-13 | 26.58% (222) | GntR family transcriptional regulator |
| M. marinum M | MMAR_3975 | - | 5e-18 | 26.05% (238) | FadR family transcriptional regulator |
| M. avium 104 | MAV_2560 | - | 1e-22 | 28.33% (233) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_4408 | - | 4e-22 | 30.43% (230) | PUTATIVE regulatory protein GntR, HTH |
| M. ulcerans Agy99 | MUL_3832 | - | 3e-18 | 26.05% (238) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4590 | - | 3e-21 | 31.84% (223) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2114|M.gilvum_PYR-GCK MARSTPLAPMIGPDAVASRTAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
Mvan_4590|M.vanbaalenii_PYR-1 MTRNTPLAPMIGPDAVASRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MAV_2560|M.avium_104 ----------------MEVTSLREPKMADRVATVLRRMFIRGEITEGTML
TH_4408|M.thermoresistible__bu ------------VEDYMEVTNLREPKMADRVATVLRRMFIRGEIPEGTML
MMAR_3975|M.marinum_M -----MTALGIGPD---PRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99 -----MTALGIGPD---PRRRLSAPRIAEIVADELRRQIIDGELADGDLL
Mb0601|M.bovis_AF2122/97 ----------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEAL
Rv0586|M.tuberculosis_H37Rv ----------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEAL
MSMEG_2605|M.smegmatis_MC2_155 -MSTDGSTTSNRRATDDIFTKVTPGRASEMILDQIRSLIRDGHLKPGDRL
MAB_4644c|M.abscessus_ATCC_199 -----------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKL
: .: : : . *. * *
Mflv_2114|M.gilvum_PYR-GCK PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRV--PGPE
Mvan_4590|M.vanbaalenii_PYR-1 PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRV--PGPE
MAV_2560|M.avium_104 PPESELMERFGVSRPTLREAFRVLESESLIQVQRGVRGGARVTR--PRRE
TH_4408|M.thermoresistible__bu PPESELMERFGVSRPTLREAFRVLESESLIVIQRGVRGGARVTR--PRRE
MMAR_3975|M.marinum_M PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHA--PAKT
MUL_3832|M.ulcerans_Agy99 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHA--PAKA
Mb0601|M.bovis_AF2122/97 PSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLD
Rv0586|M.tuberculosis_H37Rv PSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLD
MSMEG_2605|M.smegmatis_MC2_155 PSERELGDRFGVSRVTVREALRGLEANAMVTIKVGAHGGAFVTA--PTSS
MAB_4644c|M.abscessus_ATCC_199 PGEVALCEEFGVSRATVREAIRDLKTKGLVSTRQG--AGVFVTS------
* : * :.** ::***.: *.: :: : * .
Mflv_2114|M.gilvum_PYR-GCK IVARPAGLLLELSGATIADLLTAKSAIEPMAARLLAE--SGSAAAFDELE
Mvan_4590|M.vanbaalenii_PYR-1 IVARPAGLLLELSGATIADLLTAKSGIEPMAARLLAE--SGSPEAFDELE
MAV_2560|M.avium_104 TLARYAGLILEYEGVTVKDVYDARVTLEVPMVEQLAK--DRNPKVIAELE
TH_4408|M.thermoresistible__bu TLARYAGLILEYEEVTLKDVYEARMTIEMPMVVELAK--KRDPAVIAELE
MMAR_3975|M.marinum_M SAAYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELK
MUL_3832|M.ulcerans_Agy99 SAAYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELK
Mb0601|M.bovis_AF2122/97 LLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAE---RNEPELAELL
Rv0586|M.tuberculosis_H37Rv LLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAE---RNEPELAELL
MSMEG_2605|M.smegmatis_MC2_155 RVSEGIVDLLSMSGLTDIEITEARQVFELGIIPLVCER--ATEADIEELL
MAB_4644c|M.abscessus_ATCC_199 -DRPLGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIRRA
: .: .
Mflv_2114|M.gilvum_PYR-GCK QLLEELVADSHQSPRLAEATGAFHLRVVQLSGNATLSIVAGMLHEITVRH
Mvan_4590|M.vanbaalenii_PYR-1 RMLEELAADSHKSSRLAEATGLFHLRVVQLSGNATLSIVAGMLHEITVRH
MAV_2560|M.avium_104 QIVERESQLNPGSEAVDQLT-DFHAAIARLSGNSTLQIVSDMLHHIIEKA
TH_4408|M.thermoresistible__bu AIVANESNLKPGSETVDQLT-DFHAAVARLSGNKTLQIVADMLHHIVKTA
MMAR_3975|M.marinum_M RVNEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSH
MUL_3832|M.ulcerans_Agy99 RVNEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSH
Mb0601|M.bovis_AF2122/97 QDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPT
Rv0586|M.tuberculosis_H37Rv QDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPT
MSMEG_2605|M.smegmatis_MC2_155 QICDRGDAAAGQGSSSMELSAQFHTRVAEASHNAALAMLAEAFYGPTLVS
MAB_4644c|M.abscessus_ATCC_199 LVARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREA
* :. . : :
Mflv_2114|M.gilvum_PYR-GCK TAFVFNERRPV----SKADYETLLRSYRRLLQFLRSRDADGAEAHWRRHL
Mvan_4590|M.vanbaalenii_PYR-1 TAFVFNERRPV----SKADYDTLLRSYRKLMQFLRAGDAVGAEAHWRKHL
MAV_2560|M.avium_104 NRSLQPTKGTR----AEQAVRRSAKTHRMVLDMIKEGDAEKAGELWKRHL
TH_4408|M.thermoresistible__bu NRSLQPTEGTR----AEQAVRRSAKTHRMVLELIKAGDAEKAGELWQRHL
MMAR_3975|M.marinum_M EQQWADESAARGTYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIAGRHL
MUL_3832|M.ulcerans_Agy99 EQQWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHL
Mb0601|M.bovis_AF2122/97 LAALTT---------TMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLL
Rv0586|M.tuberculosis_H37Rv LAALTT---------TMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLL
MSMEG_2605|M.smegmatis_MC2_155 LRHVQEG--------HPEIGVRSSREHRQFVMAVKKGDVEKATAVMRTHL
MAB_4644c|M.abscessus_ATCC_199 MLALLAG---------SAERPHDQEHHQWLFDAIVDGSTRRAVELATDQL
: . : . * *
Mflv_2114|M.gilvum_PYR-GCK DKTRELLLAGLESVPVRDVMG------------
Mvan_4590|M.vanbaalenii_PYR-1 DTTRELLLTGLESVPVRDVMG------------
MAV_2560|M.avium_104 QKAEEFVLTGAELSTVVDLLE------------
TH_4408|M.thermoresistible__bu QKAEEFVLSGAEMSTVVDLLE------------
MMAR_3975|M.marinum_M ADTQTYVLSGRAEQRIYALSPQALSRPRDMRRP
MUL_3832|M.ulcerans_Agy99 ADTQTYVLSGRAEQRIYALSPQALSRPRDMRRP
Mb0601|M.bovis_AF2122/97 ELANTSLMAVLVSQASRQ---------------
Rv0586|M.tuberculosis_H37Rv ELANTSLMAVLVSQASRQ---------------
MSMEG_2605|M.smegmatis_MC2_155 GRTARHVKG------------------------
MAB_4644c|M.abscessus_ATCC_199 QHVRMR---------------------------
.