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M. smegmatis MC2 155 MSMEG_2531 (-)

annotation: GntR family protein transcriptional regulator
coordinates: 2617653 - 2618345
length: 230

QESATASTTSTAPPARLRLVNGLRDAISHGVLKQGERLNERELCETYNVSRTVVREGLRQLEGEGFVTIE
ANRGALVTKISYSDAEHLFEVRGALESLACSLFARRGTVEHKRALADCVADVARAMESGDLTEVLGAKDA
FYAALLAGAGNSELTTALRLLHARIRLLRRYSLSAENRQPASLAEITAICDAIIAGDIEGARRAGEYHVA
QASRAALPRIFQDLYGDST*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2531--100% (230)GntR family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_4057-2e-1834.59% (159) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_1317-5e-1828.63% (227) transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0505-1e-1027.19% (228) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_0958-5e-1126.19% (210) GntR family transcriptional regulator
M. tuberculosis H37RvRv0494-1e-1027.19% (228) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4411c-1e-1731.47% (197) GntR family transcriptional regulator
M. marinum MMMAR_0820-3e-1331.02% (216) GntR family transcriptional regulator
M. avium 104MAV_0339-2e-1229.50% (200) transcriptional regulator, GntR family protein
M. thermoresistible (build 8)TH_3038-1e-1529.05% (210) PUTATIVE putative transcriptional regulator, GntR family
M. ulcerans Agy99MUL_4564-2e-1332.58% (221) GntR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_3051-3e-1634.95% (186) GntR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0505|M.bovis_AF2122/97            MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAE
Rv0494|M.tuberculosis_H37Rv         MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAE
MMAR_0820|M.marinum_M               ----MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPERELAE
MUL_4564|M.ulcerans_Agy99           ----MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSALPPERELAE
MSMEG_2531|M.smegmatis_MC2_155      ---MQESATASTTSTAPPARLRLVNGLRDAISHGVLKQGERLN-ERELCE
MAB_4411c|M.abscessus_ATCC_199      --MTTLVPEEFAPLERQSTAELIAERLRIAIMRGVLAPGAQLG-EASLAA
Mflv_0958|M.gilvum_PYR-GCK          -MADAQLQLAALPAAEGRRAEQVMAAVRAALDAGVMRPGVKYS-VYQLAD
TH_3038|M.thermoresistible__bu      --------MSRTVESNGDASERAYQAVLQMILDGEAPAGSWLR-EQTLAE
MAV_0339|M.avium_104                ---------MAAIDISGTVRERAARELRDRILTGALPAGSRID-LDAITA
Mvan_3051|M.vanbaalenii_PYR-1       --MAAPTEEPSRLALPATLVEVAGNRLRDAILSGELAPGEKII-EEQLCA
                                                              :   :  *    *        :  

Mb0505|M.bovis_AF2122/97            RLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTHPAVVEALVRK
Rv0494|M.tuberculosis_H37Rv         RLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTHPAVVEALVRK
MMAR_0820|M.marinum_M               QLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQSLTHPAVVEALVRK
MUL_4564|M.ulcerans_Agy99           QLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQSLTHPAVVEALVRK
MSMEG_2531|M.smegmatis_MC2_155      TYNVSRTVVREGLRQLEGEGFVTIEANRG----------------ALVTK
MAB_4411c|M.abscessus_ATCC_199      QFAVSRGPLREAMQRLVSEGLLRSERNRG----------------IFVIE
Mflv_0958|M.gilvum_PYR-GCK          ALQVSRTPVRDALLRLEEIGLIRFEARQG----------------FRILL
TH_3038|M.thermoresistible__bu      QIGVSRTPVRQALNRLAAEGAIELVPNRG----------------AQVVS
MAV_0339|M.avium_104                EFATSRTPVREALLELSFEGLVQVAPRSG----------------VTVIG
Mvan_3051|M.vanbaalenii_PYR-1       DFGISRAPLREALRRLAQQGLVEHLPRRG----------------SRVTE
                                        .*  :*:.: .*   * :      *                  :  

Mb0505|M.bovis_AF2122/97            LGPDFLVELLEIRAALGPLIGRLAAARSTPE-DAEALCAALEVVQQADTA
Rv0494|M.tuberculosis_H37Rv         LGPDFLVELLEIRAALGPLIGRLAAARSTPE-DAEALCAALEVVQQADTA
MMAR_0820|M.marinum_M               LGPDFLVEVLEIRAALGPLIGRLAAERNSSE-DAEALRAALAEVADADTA
MUL_4564|M.ulcerans_Agy99           LGPDFLVEVLEIRAALGPLIGRLAAERNSSE-DAEALRAALAEVADADTA
MSMEG_2531|M.smegmatis_MC2_155      ISYSDAEHLFEVRGALESLACSLFARRGTVE-HKRALADCVADVARAMES
MAB_4411c|M.abscessus_ATCC_199      LTDDDVLDVYRSRSAIERAALECIMTGDTVT-AYRRLLVPVAVMTEAAAR
Mflv_0958|M.gilvum_PYR-GCK          PDPREIADIVAIRFALEPPAAGRAAAVCGPP-LADRLAERMELLRRAAAR
TH_3038|M.thermoresistible__bu      FSDEDVEALFDLRARFEPLAVRLAVPQLTEE-RIAELADLATRMEALLDR
MAV_0339|M.avium_104                ISPEDVLDSFTILGVLTGQAAAWAAERIGPE-ELATLRELAAEVVAKSGD
Mvan_3051|M.vanbaalenii_PYR-1       WSPTDILQLFELRNVLERHAIESALPLADLDRDLEPVRAALEQMDASSDV
                                                   :                    :      :      

Mb0505|M.bovis_AF2122/97            A-----ARQAADLAYFRVLIHSTRNRALGLLYR--WVEHAFGGREHALTG
Rv0494|M.tuberculosis_H37Rv         A-----ARQAADLAYFRVLIHSTRNRALGLLYR--WVEHAFGGREHALTG
MMAR_0820|M.marinum_M               P-----ARQAADLAYFRVLIHGTRNRALGLLYR--WVEQAFGGREHELTG
MUL_4564|M.ulcerans_Agy99           P-----ARQAADLAYFRVLIHGTRNRALGLLYR--WVEQAFGGREHDLTG
MSMEG_2531|M.smegmatis_MC2_155      GDLT--EVLGAKDAFYAALLAGAGNSELTTALR--LLHARIRLLRRYSLS
MAB_4411c|M.abscessus_ATCC_199      GDVV--AVTDADQDFHEVLVDCSGSPRLRRAMR--TLLLETRMLLGELQG
Mflv_0958|M.gilvum_PYR-GCK          GDEP--GFAAHDLLLHDHILEAAGNNRARRIVR--SLRESTRLLGGITAD
TH_3038|M.thermoresistible__bu      RPLDTHQMSRLNNAFHGIFLAEAGNRHLTAAMQ--AVVRPALVTLTFQKY
MAV_0339|M.avium_104                D-----SIGEANWHFHQMIHRAAHSPRLANQIK--HAARVVP--TNFLTL
Mvan_3051|M.vanbaalenii_PYR-1       L-----SLDDAHRAFHAAVVGLAKNRQLDIALEPILLKLQLPMARNMREE
                                               .   .  .   : .       .                 

Mb0505|M.bovis_AF2122/97            AYDDADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRDRA
Rv0494|M.tuberculosis_H37Rv         AYDDADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRDRA
MMAR_0820|M.marinum_M               AYEDADPVIADLTAINDAVLAGDPETAAAAVEGYLNASALRMIMCYRAAY
MUL_4564|M.ulcerans_Agy99           AYEDADPVIADLTAINDAVLAGDPETAAAAVEGYLNASALRMIMCYRAAY
MSMEG_2531|M.smegmatis_MC2_155      AENRQPASLAEITAICDAIIAGDIEGARRAGEYHVAQASRAALPRIFQDL
MAB_4411c|M.abscessus_ATCC_199      AYPDLSEQVREHEVLCAAIGAGDAPAAYRLIDEHMHDAVTRLMARRDPGS
Mflv_0958|M.gilvum_PYR-GCK          RSRTMSDIDAEHQPVVDAVIANDPAAAAAAMRTHLTSTGRLLVAQAVRDQ
TH_3038|M.thermoresistible__bu      SERALRLSMHHHAELVEAARARDPEWAEAVMRAHILAARHAGE-------
MAV_0339|M.avium_104                FPEHEKHSLDEHAQLLDALGDKDVERARAIAERHVLDAGRSLAEWLEQRR
Mvan_3051|M.vanbaalenii_PYR-1       ARQHAGPGRRHRPGAADEGIGRHKAILSALETNDPAAVVTAIRDHGHLHY
                                              .           .                           

Mb0505|M.bovis_AF2122/97            ---------------------
Rv0494|M.tuberculosis_H37Rv         ---------------------
MMAR_0820|M.marinum_M               AGEDPER--------------
MUL_4564|M.ulcerans_Agy99           AGEDPER--------------
MSMEG_2531|M.smegmatis_MC2_155      YGDST----------------
MAB_4411c|M.abscessus_ATCC_199      VE-------------------
Mflv_0958|M.gilvum_PYR-GCK          DSPLDAAAVWAEAVGANTELP
TH_3038|M.thermoresistible__bu      ---------------------
MAV_0339|M.avium_104                DGER-----------------
Mvan_3051|M.vanbaalenii_PYR-1       LGLAP----------------