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LKDDVLAVLRDAIIAGKFAPGERLNEKDLAEQLGTSRGPIRDSLAALAHEGLVVHEPHKGARVPLLDKAD IEDVYTLRVALETLAARTAVERARAADFDALDHALSDLAKAFEKGDRRGITDADLRFHDAFYQAAHHDRL SVAWRTVRSQVALCLFSRNTVSATSREIVVDEHVHLLDLLRTRSESALVDAVRAHIETAYQRLVASYD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4057 | - | - | 100% (208) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_6738 | - | 8e-21 | 30.85% (201) | transcriptional regulator YdhC |
| M. smegmatis MC2 155 | MSMEG_2489 | - | 6e-19 | 29.08% (196) | transcriptional regulator, GntR family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 2e-17 | 30.21% (192) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0958 | - | 8e-19 | 31.53% (203) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 8e-17 | 33.33% (144) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4411c | - | 2e-17 | 31.00% (200) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0408 | - | 4e-19 | 32.12% (193) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5020 | - | 2e-20 | 31.25% (208) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_0156 | - | 4e-17 | 30.66% (212) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1058 | - | 2e-18 | 31.61% (193) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0130 | - | 3e-21 | 32.37% (207) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSAR-
MUL_1058|M.ulcerans_Agy99 -----------------------------------------MNILLSAR-
MAV_5020|M.avium_104 ---------------------------------------------MSMQ-
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAK-
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAK-
TH_0156|M.thermoresistible__bu -----------------------------------------MNAPITSRL
Mvan_0130|M.vanbaalenii_PYR-1 -----------------------------------------MNAPART--
MSMEG_4057|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4411c|M.abscessus_ATCC_199 ---------------------------------------------MTTLV
Mflv_0958|M.gilvum_PYR-GCK --------------------------------------------MADAQL
MMAR_0408|M.marinum_M RKSRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP
MUL_1058|M.ulcerans_Agy99 RESRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITP
MAV_5020|M.avium_104 PRSRRPLRRAQLSDEVAGHLRAAIMSGALRPGTFIRLDETAAELGVSVTP
Mb0170c|M.bovis_AF2122/97 PRSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
Rv0165c|M.tuberculosis_H37Rv PRSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
TH_0156|M.thermoresistible__bu GPNGGGRRRDQLSDEVAAQLRAEIMSGALRPGTYIRLDETAARLGVSITP
Mvan_0130|M.vanbaalenii_PYR-1 -PVAGAVRREQLSDEVAARLRAEIMTGALRPDSFIRLDETAARLGVSITP
MSMEG_4057|M.smegmatis_MC2_155 -----------MKDDVLAVLRDAIIAGKFAPGERLNEKDLAEQLGTSRGP
MAB_4411c|M.abscessus_ATCC_199 PEEFAPLERQSTAELIAERLRIAIMRGVLAPGAQLGEASLAAQFAVSRGP
Mflv_0958|M.gilvum_PYR-GCK QLAALPAAEGRRAEQVMAAVRAALDAGVMRPGVKYSVYQLADALQVSRTP
: : :* : * : .. . * : .* *
MMAR_0408|M.marinum_M VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTA
MUL_1058|M.ulcerans_Agy99 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTA
MAV_5020|M.avium_104 VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIEDIFWLQATIAKELAAAA
Mb0170c|M.bovis_AF2122/97 VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA
Rv0165c|M.tuberculosis_H37Rv VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA
TH_0156|M.thermoresistible__bu IREALRTLRGEGMVQLEPHRGHVVAPLTRGDIEDIFWLQATIARKLTAAA
Mvan_0130|M.vanbaalenii_PYR-1 VREALRTLRGEGMVELEPHRGHRVVPLTRTDIEDIFWLQSTIAQELAATA
MSMEG_4057|M.smegmatis_MC2_155 IRDSLAALAHEGLVVHEPHKGARVPLLDKADIEDVYTLRVALETLAARTA
MAB_4411c|M.abscessus_ATCC_199 LREAMQRLVSEGLLRSERNRGIFVIELTDDDVLDVYRSRSAIERAALECI
Mflv_0958|M.gilvum_PYR-GCK VRDALLRLEEIGLIRFEARQGFRILLPDPREIADIVAIRFALEPPAAGRA
:*::: * *:: * .:* : :: *: : ::
MMAR_0408|M.marinum_M TERISEIDIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIK
MUL_1058|M.ulcerans_Agy99 TERISEVVIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIK
MAV_5020|M.avium_104 TDHITDTEIDELDRINDALAAAVGSGDAETIAGLEFGFHRVFNQASGRIK
Mb0170c|M.bovis_AF2122/97 TAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIK
Rv0165c|M.tuberculosis_H37Rv TAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIK
TH_0156|M.thermoresistible__bu VDRITDAELDELTALNEALAAAVDRGVVGEVAAAMSAFHRVLHRTTGRIK
Mvan_0130|M.vanbaalenii_PYR-1 ARNITDAQIDELAQLNERLAEAVEQRDPDRVARAEFTFHRAFNRAGGRIK
MSMEG_4057|M.smegmatis_MC2_155 VERARAADFDALDHALSDLAKAFEKGDRRGITDADLRFHDAFYQAAHHDR
MAB_4411c|M.abscessus_ATCC_199 MTGDTVTAYRRLLVPVAVMTEAAARGDVVAVTDADQDFHEVLVDCSGSPR
Mflv_0958|M.gilvum_PYR-GCK AAVCGPPLADRLAERMELLRRAAARGDEPGFAAHDLLLHDHILEAAGNNR
* : * .: :* : :
MMAR_0408|M.marinum_M LAWFLLNAARYMPAQLY---ASDPQWGAAAVDNHRQLIAALRRRDTAAVI
MUL_1058|M.ulcerans_Agy99 LAWFLLNAARYMPAQLY---ASDPQWGAAAVDNHRQLIAALRRRDTAAVI
MAV_5020|M.avium_104 LAWFLLNAARYMPVLVY---AADPQWGRAAVDNHRQLIAALRRRDTAAVI
Mb0170c|M.bovis_AF2122/97 LAWFLLNAARYMPAQVF---AADPRWGADAVNSHRQLIAALRRRDTAAVI
Rv0165c|M.tuberculosis_H37Rv LAWFLLNAARYMGAGVR---GRP----AMGRGRGEQSSAADRR---AAPP
TH_0156|M.thermoresistible__bu LAWFLYHVARYMPPQIY---ATDQQWGTATVARHRELIAALRRRDTETAT
Mvan_0130|M.vanbaalenii_PYR-1 LAWFLLHAARYLPPQLF---ASDETWGPVAVASHAELIEALRRRDVDTVV
MSMEG_4057|M.smegmatis_MC2_155 LSVAWRTVRSQVALCLFSRNTVSATSREIVVDEHVHLLDLLRTRSESALV
MAB_4411c|M.abscessus_ATCC_199 LRRAMRTLLLETRMLLG-ELQGAYPDLSEQVREHEVLCAAIGAGDAPAAY
Mflv_0958|M.gilvum_PYR-GCK ARRIVRSLRESTRLLGG-ITADRSRTMSDIDAEHQPVVDAVIANDPAAAA
:
MMAR_0408|M.marinum_M EHSVWQFTDAAHRLTQM--------LETNGIFN----------
MUL_1058|M.ulcerans_Agy99 EHSVWQFTDAAHRLTQM--------LETNGIFN----------
MAV_5020|M.avium_104 EHTVWQFTDAAARLTAM--------RDRTGTPSNRG-------
Mb0170c|M.bovis_AF2122/97 EHTVWQFTDGARRLTEA--------LAETEVFG----------
Rv0165c|M.tuberculosis_H37Rv RHSRR---NRAHRLAVH--------RWGTQADGGPG-------
TH_0156|M.thermoresistible__bu RVTVDLFTDSAQRLIAQ--------LEKVGIWT----------
Mvan_0130|M.vanbaalenii_PYR-1 ELTRGQFTDGRARLIAW--------LEQVGLWS----------
MSMEG_4057|M.smegmatis_MC2_155 DAVRAHIETAYQRLVAS--------YD----------------
MAB_4411c|M.abscessus_ATCC_199 RLIDEHMHDAVTRLMAR--------RDPGSVE-----------
Mflv_0958|M.gilvum_PYR-GCK AAMRTHLTSTGRLLVAQAVRDQDSPLDAAAVWAEAVGANTELP
*