For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPDKPPEKQAAASPRRRGVKAMPPDLGPRTRAEQLAAVIDARIRDGEFRPGESIGTLESLRAETKFAYST VSEAVRLLRDRGIIEIRPGRGGGLFVADAGPVVRMRRTLLRVSDHPETVADAVELRDHLEILIATSAARH RTTRDVADLRALLVAMEQADTWEDFVRENWVLHERIAQICPNEMARAVYVGTLGHLRSTSSSSLDDHTSD KYRQQRVHVHRELVDAIESGDENAVRDVVTRHNAAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2480 | - | - | 100% (246) | transcriptional regulator, GntR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_2173 | - | 6e-13 | 24.22% (223) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2794 | - | 3e-12 | 29.67% (209) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3086c | - | 6e-09 | 26.98% (215) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4061 | - | 8e-11 | 37.23% (137) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv3060c | - | 6e-09 | 26.98% (215) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 2e-13 | 27.03% (222) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0749 | - | 1e-09 | 29.72% (212) | GntR family transcriptional regulator |
| M. avium 104 | MAV_3932 | - | 3e-13 | 29.69% (229) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_4465 | - | 1e-08 | 25.79% (221) | PUTATIVE putative hydride transferase 1 |
| M. ulcerans Agy99 | MUL_3832 | - | 2e-09 | 25.11% (235) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1986 | - | 4e-12 | 28.14% (231) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4644c|M.abscessus_ATCC_199 ---------------------------------------------MHPRL
MMAR_0749|M.marinum_M ----------------------------------------------MQTV
MUL_3832|M.ulcerans_Agy99 ------------------------------------MTALGIGPDPRRRL
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------MPAQRI
Mb3086c|M.bovis_AF2122/97 ------------------------------------------MSTEPDAV
Rv3060c|M.tuberculosis_H37Rv ------------------------------------------MSTEPDAV
MAV_3932|M.avium_104 ------------------------------------------MNAEPRTG
Mflv_4061|M.gilvum_PYR-GCK ------------------------------MAAPDPADSSDASEALLRPV
MSMEG_2480|M.smegmatis_MC2_155 ------------------------MPDKPPEKQAAASPRRRGVKAMPPDL
TH_4465|M.thermoresistible__bu LATIGLSAYGMAGGELVELAACADELGFDTLWLGEHVVRPLTQRSAHPTS
MAB_4644c|M.abscessus_ATCC_199 SSQSLAEQVANILAAQIGDGRWSTGAKLPGEVALCEEFGVSRATVREAIR
MMAR_0749|M.marinum_M RRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCEMTGTARNTVREAVQ
MUL_3832|M.ulcerans_Agy99 SAPRIAEIVADELRRQIIDGELADGDLLPRQEVLVEQFNVSLVSLREALR
Mvan_1986|M.vanbaalenii_PYR-1 RQPRVAELVASRLRDDILTGRLKEGDVLPSQEALFAEFGVSPPAVREAVH
Mb3086c|M.bovis_AF2122/97 WTDKRASKIARRIEADIVRRGWPIGASLGSESALQQRFCVSRSVLREAVR
Rv3060c|M.tuberculosis_H37Rv WTDKRASKIARRIEADIVRRGWPIGASLGSESALQQRFCVSRSVLREAVR
MAV_3932|M.avium_104 PAKTLASALARDIEAEIVRRGWAVGESLGSEPALQQRFGVSRSVLREAVR
Mflv_4061|M.gilvum_PYR-GCK RPLNAFEDTVERLLQTIRLGVLTPGESLPPERELAARLGVSRDTVREAIK
MSMEG_2480|M.smegmatis_MC2_155 GPRTRAEQLAAVIDARIRDGEFRPGESIGTLESLRAETKFAYSTVSEAVR
TH_4465|M.thermoresistible__bu GTRQHHSGPLVAERTELIDPWAVHAAIAAVTTGIKLGTAVYVAALRHPLH
: . : : ..::
MAB_4644c|M.abscessus_ATCC_199 DLKTKGLVSTRQGAGVFVTSDRPLG-QWDRVLAAAEID------AVVEIR
MMAR_0749|M.marinum_M ALVHVGILERRQGSGTYVIADVEQGSALAEYFAAARER------DLWELR
MUL_3832|M.ulcerans_Agy99 ILETEGLVSVRRGNRGGAVVHAPAKASAAYMLGLLLQSESVAVSDLGAAL
Mvan_1986|M.vanbaalenii_PYR-1 ILESDGLISVRRGNIGGAVVHLPSAERTAQMISMVLQTRSATPADVSEAL
Mb3086c|M.bovis_AF2122/97 LVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYLEYLGTTIGDLLGAR
Rv3060c|M.tuberculosis_H37Rv LVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYLEYLGTTIGDLLGAR
MAV_3932|M.avium_104 LVEHHQVARMRRGPNGGLYICEPDAGPATRAVVIYLEYLGTTLADLLNAR
Mflv_4061|M.gilvum_PYR-GCK SLADAGYLVSRRGRYGGTFLADALPAPRADGTEMHRDD----IDDAVRLR
MSMEG_2480|M.smegmatis_MC2_155 LLRDRGIIEIRPGRGGGLFVADAGPVVRMRRTLLRVSDHPETVADAVELR
TH_4465|M.thermoresistible__bu TARTTITVQELSGGRVVFGVGVGWLEEEFDAFDVPFRTRVSRTEECLAIL
*
MAB_4644c|M.abscessus_ATCC_199 -------------RLLEVQAAGLAAERRNRSDVAAIRRALVAR-----AK
MMAR_0749|M.marinum_M -------------EAVEVTAAVLSARRRDAADIEDLRALLARRNELWSRE
MUL_3832|M.ulcerans_Agy99 -------------QELEPACAALAAQRPDRADTLVPELKRVNE-----AM
Mvan_1986|M.vanbaalenii_PYR-1 -------------LHLEPICAGMCASRGDRMTEVVPHLQAAID-----VQ
Mb3086c|M.bovis_AF2122/97 -------------LVLEPLAASLAAEHIDEPGIERLRAVLRAE-------
Rv3060c|M.tuberculosis_H37Rv -------------LVLEPLAASLAAEHIDEPGIERLRAVLRAE-------
MAV_3932|M.avium_104 -------------LVLEPLAASLAAERIDEAGIARLRAVLHAE-------
Mflv_4061|M.gilvum_PYR-GCK -------------EILEVGAARMAAVRTLAAVEREALRSRLTD-------
MSMEG_2480|M.smegmatis_MC2_155 -------------DHLEILIATSAARHRTTRDVADLRALLVAM-------
TH_4465|M.thermoresistible__bu RAAWRGEPFSHHGRHFRIDRVQVHSRPVDIPVVLGGNGPKALARAATLGD
.. . :
MAB_4644c|M.abscessus_ATCC_199 AESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAMLALLA
MMAR_0749|M.marinum_M PANDKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAVEAGPV
MUL_3832|M.ulcerans_Agy99 SEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ-QWA
Mvan_1986|M.vanbaalenii_PYR-1 VEQFDRTSRYVSNARRFHEAIVSRCGNEPMILLIGSLELIWSAHESSVWS
Mb3086c|M.bovis_AF2122/97 ---ERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGT
Rv3060c|M.tuberculosis_H37Rv ---ERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGT
MAV_3932|M.avium_104 ---QQWRPGLPMPRDEFHIALAEQSKNPVLQLFIKVLMRLTTRYALQSRT
Mflv_4061|M.gilvum_PYR-GCK -VRGADPADYRRLDSRLHLAIAEAAGVPSLVPLVAQNRMRLNELLDRIPL
MSMEG_2480|M.smegmatis_MC2_155 -EQADTWEDFVRENWVLHERIAQICPNEMARAVYVGTLGHLRSTSSSSLD
TH_4465|M.thermoresistible__bu GWFTSGTPEFDDALRMVREIRRVREQHGRPGPFTCYVRIPSVDEVGRYRD
. .
MAB_4644c|M.abscessus_ATCC_199 GSAERPH----------DQEHHQWLFDAIVD-------------------
MMAR_0749|M.marinum_M GTCTS------------YEREHTELVEAIIA-------------------
MUL_3832|M.ulcerans_Agy99 DESAARGTYPSLAKRRAVLNAHIKLTETIAE-------------------
Mvan_1986|M.vanbaalenii_PYR-1 DECHPEDPMRPKTMR-AALRDHHRIVEAIID-------------------
Mb3086c|M.bovis_AF2122/97 QSAGEAVEAAG-----QVHNEHSDIVAAVTA-------------------
Rv3060c|M.tuberculosis_H37Rv QSAGEAVEAAG-----QVHNEHSDIVAAVTA-------------------
MAV_3932|M.avium_104 DSETEALEAVD-----HLHTHHSRIVAAVTA-------------------
Mflv_4061|M.gilvum_PYR-GCK MTRNIAHS----------DEQHEAIVSAILA-------------------
MSMEG_2480|M.smegmatis_MC2_155 DHTSDKYRQQR-------VHVHRELVDAIES-------------------
TH_4465|M.thermoresistible__bu HDMTDLVLWADTVWQGRTLDEKRDRLAAAADRLGLVSRSSGDPPAAAAGR
: :
MAB_4644c|M.abscessus_ATCC_199 ------GSTRRAVELATDQLQHVRMR------------------------
MMAR_0749|M.marinum_M ------GDPQRAEAAAQVFIARLRP-------------------------
MUL_3832|M.ulcerans_Agy99 ------GDVDRARRIAGRHLADTQTYVLSGRAEQRIYALSPQALSRPRDM
Mvan_1986|M.vanbaalenii_PYR-1 ------GNSSRAVRLAEDHLAAARHNTLAAGSDRTIEAKLIANHDR----
Mb3086c|M.bovis_AF2122/97 ------GDSAWAKTLSERHVEAVAGWLQQHQRGNDAAVRNGGRAREPRRA
Rv3060c|M.tuberculosis_H37Rv ------GDSAWAKTLSERHVEAVAGWLQQHQRGNDAAVRNGGRAREPRRA
MAV_3932|M.avium_104 ------GDPARAKTLSERHVEAVTAWLQRHHAGD----RN--RGRTPRRP
Mflv_4061|M.gilvum_PYR-GCK ------GDADTAAQTMAAHVWGSAALLHGFLD------------------
MSMEG_2480|M.smegmatis_MC2_155 ------GDENAVRDVVTRHNAAV---------------------------
TH_4465|M.thermoresistible__bu SQRRRSGSALRMGDDVPRRVQNTGARSAGVRDTRPQNSRAGANGARTARD
*.
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 RRP-----------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 QQLILGAPRGKLAEVLAAT--IGDDIAASGWQVGSVFGTETALLERYQVS
Rv3060c|M.tuberculosis_H37Rv QQLILGAPRGKLAEVLAAT--IGDDIAASGWQVGSVFGTETALLERYQVS
MAV_3932|M.avium_104 --LNSEVPQGKLAEMLAAT--IGDDIAADGWRVGSVFGTETALLQRYRVS
Mflv_4061|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2480|M.smegmatis_MC2_155 --------------------------------------------------
TH_4465|M.thermoresistible__bu EHRGEVSLLRPLKAAESVARMIVDEIKTKGLQPGDSLPLEATMLKQYGVS
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 RAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQPQASIDTIALYLQYRKP
Rv3060c|M.tuberculosis_H37Rv RAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQPQASIDTIALYLQYRKP
MAV_3932|M.avium_104 RAVFREAVRLLEYHSIAHMRRGPGGGLVIAEPAAQASIDTIALYLQYRDP
Mflv_4061|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2480|M.smegmatis_MC2_155 --------------------------------------------------
TH_4465|M.thermoresistible__bu RESLREGLRLLEVQGMISIRRGPGGGPVVGTVDAGHLGRVSALFYNMADA
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 SREDLRCVRDAIEIDNVAKVVKRRSEPEVASFLDTLGRPRLDN---PTDD
Rv3060c|M.tuberculosis_H37Rv SREDLRCVRDAIEIDNVAKVVKRRSEPEVASFLDTLGRPRLDN---PTDD
MAV_3932|M.avium_104 SREDLRCVRDAIEIDNVAKVVKRLAEPQVAAFVASRRSGLPDDSRQTPDD
Mflv_4061|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2480|M.smegmatis_MC2_155 --------------------------------------------------
TH_4465|M.thermoresistible__bu TYEELLEAWVWAEG----ELAERAARNPDAQLRSARMTPYLTDHDGSAEG
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 VRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFRRHLSSTEQALPTWS
Rv3060c|M.tuberculosis_H37Rv VRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFRRHLSSTEQALPTWS
MAV_3932|M.avium_104 VRRAIAEEFDFHVGLAQLAGNAPLDLFLRIIVELFRRHWSSTGQALPTWS
Mflv_4061|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2480|M.smegmatis_MC2_155 --------------------------------------------------
TH_4465|M.thermoresistible__bu LAPYLEGHTAFHRAVADLSNNRVLALSLQTYGQIVSHHVAVLSDPR---S
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 DVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAASWWL----------
Rv3060c|M.tuberculosis_H37Rv DVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAASWWL----------
MAV_3932|M.avium_104 DVRAVHHAHLRIADAVAAGDLSVASYRLRRHLDAAASWWL----------
Mflv_4061|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2480|M.smegmatis_MC2_155 --------------------------------------------------
TH_4465|M.thermoresistible__bu LRDVLVDEHRHIAEAVISGHARRARALMRSHLEGVTAFVRENIPVPLDQP
MAB_4644c|M.abscessus_ATCC_199 ----
MMAR_0749|M.marinum_M ----
MUL_3832|M.ulcerans_Agy99 ----
Mvan_1986|M.vanbaalenii_PYR-1 ----
Mb3086c|M.bovis_AF2122/97 ----
Rv3060c|M.tuberculosis_H37Rv ----
MAV_3932|M.avium_104 ----
Mflv_4061|M.gilvum_PYR-GCK ----
MSMEG_2480|M.smegmatis_MC2_155 ----
TH_4465|M.thermoresistible__bu IEWL