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VAEQLRPVTRPRLYEVIVEQLCAYIYSNEMEPGDRLPAERDLAAKLGVSRASLSQALVALEVQGVLSVRH GDGAILIRRPTEEGSIRALREHADRIPDIIEAREALEVKLAELAAARRTDAEMAAIDAAIATMEKEVEAG ERGVMGDEMFHEAITSAAHSSLLAKLMHEIAGLIRETRIESLSQENRPRASLEGHRRIADAIRKQDSQAA AQAMAEHIRMVSDVALLREG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2173 | - | - | 100% (230) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5375 | - | 7e-37 | 38.60% (228) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0895 | - | 5e-22 | 31.88% (229) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0505 | - | 4e-16 | 33.95% (162) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 1e-19 | 31.48% (216) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0494 | - | 4e-16 | 33.95% (162) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 2e-18 | 32.24% (214) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4029 | - | 9e-15 | 27.27% (209) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1576 | - | 1e-14 | 27.83% (212) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_1959 | - | 1e-17 | 31.17% (231) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (GNTR-FAMILY) |
| M. ulcerans Agy99 | MUL_3894 | - | 1e-13 | 26.32% (209) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0294 | - | 2e-22 | 33.50% (200) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0505|M.bovis_AF2122/97 MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAE
Rv0494|M.tuberculosis_H37Rv MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAE
Mflv_0016|M.gilvum_PYR-GCK MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNETVLVE
MAB_4644c|M.abscessus_ATCC_199 MHPR------LSSQ---SLAEQVANILAAQIGDGRWSTGAKLPGEVALCE
MMAR_4029|M.marinum_M MTDP-------EFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLD-QLAA
MUL_3894|M.ulcerans_Agy99 MTDP-------EFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLD-QLAA
MAV_1576|M.avium_104 MSVP-------DFAARPQLSDDVAHLIRGRIFDGSYAAGSYVRLD-QLAA
MSMEG_2173|M.smegmatis_MC2_155 MAEQ------LRPVTRPRLYEVIVEQLCAYIYSNEMEPGDRLPAERDLAA
Mvan_0294|M.vanbaalenii_PYR-1 MNAPGGEAIPPLIRRPQSVSVALAAHFERLIATGEISPGTRLPSERELAA
TH_1959|M.thermoresistible__bu --------MALQPVNRRSVPEDVFDQIVGEVLSGQMQPGDALPSERRLAE
: : . : * : : *
Mb0505|M.bovis_AF2122/97 RLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPE---GLTHPAVVEAL
Rv0494|M.tuberculosis_H37Rv RLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPE---GLTHPAVVEAL
Mflv_0016|M.gilvum_PYR-GCK KFGVGRNTVREAVRALAHAGILEVRQGDGTYVRA---------TSEVSGA
MAB_4644c|M.abscessus_ATCC_199 EFGVSRATVREAIRDLKTKGLVSTRQGAGVFVTS---------DRPLGQW
MMAR_4029|M.marinum_M ELGISVTPVREALFALRAEGLVAQQPHRGFVVLP----------------
MUL_3894|M.ulcerans_Agy99 ELGISVTPVREALFALRAEGLVAQQPHRGFVVLP----------------
MAV_1576|M.avium_104 ELGISVTPVREALFALRAEGLISQQPRRGFVVLP----------------
MSMEG_2173|M.smegmatis_MC2_155 KLGVSRASLSQALVALEVQGVLSVRHGDGAILIR-------RPTEEGSIR
Mvan_0294|M.vanbaalenii_PYR-1 SMSVSRSSLREAMHELESKRLVSRTRGRGTIVLAP-------TASVDELL
TH_1959|M.thermoresistible__bu VLGVSRPAVREALKRLSAAGLVEVRQGEITTVRDYRRHAGLDLLPRLLFR
:.:. .: :.: * :: :
Mb0505|M.bovis_AF2122/97 VRKLGPDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAALEVVQQAD
Rv0494|M.tuberculosis_H37Rv VRKLGPDFLVELLEIRAALGPLIGRLAAARSTPEDAEALCAALEVVQQAD
Mflv_0016|M.gilvum_PYR-GCK LRRLCGEELREVLEVRRALEVEAARLAASRRTPADVAEMRGLLARRDERD
MAB_4644c|M.abscessus_ATCC_199 DRVLAAAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIRRALVARAKAE
MMAR_4029|M.marinum_M ---LTKRDLADVAYVQAHVGGELAARAAINIGAAQLAELQQIQAQLEEAY
MUL_3894|M.ulcerans_Agy99 ---LTKRDLADVAYVQAHVGGELAARAAINIGAAQLAELQQIQAQLEEAY
MAV_1576|M.avium_104 ---VTRRDVTDVANVQAHVGGELAARAAVNITDDQLRELKQIQAQLEDAY
MSMEG_2173|M.smegmatis_MC2_155 ALREHADRIPDIIEAREALEVKLAELAAARRTDAEMAAIDAAIATMEKEV
Mvan_0294|M.vanbaalenii_PYR-1 AIAGGGTEQEHAAELRSVIEPSIAELAAHRATSANVLQLRDVLDKSHENL
TH_1959|M.thermoresistible__bu AGELDVTVVRSILETRLHNGPKVAELAARRRPPGLGALLDEAVQTLAAET
: . ** . :
Mb0505|M.bovis_AF2122/97 TA---AARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGREHALTGAY
Rv0494|M.tuberculosis_H37Rv TA---AARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGGREHALTGAY
Mflv_0016|M.gilvum_PYR-GCK SAGDVEAFARIDTEFHLAVVRCARNNTLIELYR----GLLEAVTASVAHT
MAB_4644c|M.abscessus_ATCC_199 SAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAMLALLAGS
MMAR_4029|M.marinum_M AADDDERTVRLNHEFHRAINLAADSPRLSQLMSQITRYQPESVFPGIEHW
MUL_3894|M.ulcerans_Agy99 AADDDERTVRLNHEFHRAINLAADSPRLSQLMSQITRYQPESVFPGIEHW
MAV_1576|M.avium_104 AGDEHERTVRLNHEFHRAINIAADSPKLAQLMSQITRYAPESVFPAIQGW
MSMEG_2173|M.smegmatis_MC2_155 EAG--ERGVMGDEMFHEAITSAAHSSLLAKLMHEIAGLIRETRIESLSQE
Mvan_0294|M.vanbaalenii_PYR-1 LQ---AESLRLDIEFHLLLAQAAQNPLLTALQTLASEWTGEVRKHSHSTR
TH_1959|M.thermoresistible__bu DP---VERQRHALRFWDHVVDGADSIAFRLMYNTLRATYEPALPALATMM
: : . . : :
Mb0505|M.bovis_AF2122/97 DDADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRDRA--
Rv0494|M.tuberculosis_H37Rv DDADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRDRA--
Mflv_0016|M.gilvum_PYR-GCK RHVPVDVCDHGVLLDHIAAGDPDLAARTAGEFLDRIINGLGSADSS----
MAB_4644c|M.abscessus_ATCC_199 AERPHDQEHHQWLFDAIVDGSTRRAVELATDQLQHVRMR-----------
MMAR_4029|M.marinum_M PAR--AVKDHRRVLVALKKHDDKAARTAMSEHLASSAVPLIDHLIARGVV
MUL_3894|M.ulcerans_Agy99 PAR--AVKDHGQVLVALKKHDDKAARTAMSEHLASSAVPLIDHLIARGVV
MAV_1576|M.avium_104 PEQ--SMKDHRRILSALKKRDDKLARAAMSEHLAAGAVPLIDHLVARGVV
MSMEG_2173|M.smegmatis_MC2_155 NRPRASLEGHRRIADAIRKQDSQAAAQAMAEHIRMVSDVALLREG-----
Mvan_0294|M.vanbaalenii_PYR-1 HGRCASVRGHQEIFDAVRTHDGLAARQAMEDHLRDVSELVAKATRS----
TH_1959|M.thermoresistible__bu AAEVGRPQAYRALAAAIEAGDPTAAEQSARDLLEPATAALLSALDELEAQ
: : . * :
Mb0505|M.bovis_AF2122/97 ----------------
Rv0494|M.tuberculosis_H37Rv ----------------
Mflv_0016|M.gilvum_PYR-GCK ----------------
MAB_4644c|M.abscessus_ATCC_199 ----------------
MMAR_4029|M.marinum_M AESAPSGSAAERARGG
MUL_3894|M.ulcerans_Agy99 AESAPSGSAAERARGG
MAV_1576|M.avium_104 VD----GGGPDPG---
MSMEG_2173|M.smegmatis_MC2_155 ----------------
Mvan_0294|M.vanbaalenii_PYR-1 ----------------
TH_1959|M.thermoresistible__bu K---------------