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M. thermoresistible (build 8) TH_4465 (-)

annotation: putative hydride transferase 1
coordinates: 765713 - 767506
length: 598

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4465--100% (598)putative hydride transferase 1
M. thermoresistible (build 8)TH_2478-8e-4641.83% (251) PUTATIVE putative regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_4081-2e-3132.45% (265) PUTATIVE putative hydride transferase 1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0965c-1e-2529.44% (248) oxidoreductase
M. gilvum PYR-GCKMflv_4839-7e-3134.41% (247) luciferase family protein
M. tuberculosis H37RvRv0940c-1e-2529.44% (248) oxidoreductase
M. leprae Br4923MLBr_00348-9e-1528.57% (203) putative coenzyme F420-dependent oxidoreductase
M. abscessus ATCC 19977MAB_0366-1e-2231.51% (219) hypothetical protein MAB_0366
M. marinum MMMAR_1586-4e-3237.50% (208) oxidoreductase
M. avium 104MAV_2247-7e-3031.95% (266) hypothetical protein MAV_2247
M. smegmatis MC2 155MSMEG_2811-2e-3434.09% (264) hydride transferase 1
M. ulcerans Agy99MUL_3448-1e-3137.50% (208) oxidoreductase
M. vanbaalenii PYR-1Mvan_3595-1e-2733.64% (214) luciferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0965c|M.bovis_AF2122/97           -----MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSK
Rv0940c|M.tuberculosis_H37Rv        -----MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSK
MAV_2247|M.avium_104                -----MRFYVSSAFLNTREIIEIARAADELGYDGIGIPDHVVNLETLDTP
Mvan_3595|M.vanbaalenii_PYR-1       -----MKFYVSTAFLDTREAVEIAKAADDLGYHGMAIPDHVINLETLQTP
MMAR_1586|M.marinum_M               MQLGLHA-LGIGAGADRSMIDAVACAADDAGFATLWAGEHVVMVDRHTSR
MUL_3448|M.ulcerans_Agy99           MQLGLHA-LEIGAGADRSMIDAVACAADDAGFATLWAGEHVVMVDRHTSR
MSMEG_2811|M.smegmatis_MC2_155      MQISLHA-LGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVMVDRPRSR
Mflv_4839|M.gilvum_PYR-GCK          ------------------MIDAVAASAERSGFETLWFGDQVVMADEDGPH
MAB_0366|M.abscessus_ATCC_1997      MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVVIGDTQST
TH_4465|M.thermoresistible__bu      ----LATIGLSAYGMAGGELVELAACADELGFDTLWLGEHVVRPLTQRSA
MLBr_00348|M.leprae_Br4923          -------------MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGF
                                                          ..      .                   

Mb0965c|M.bovis_AF2122/97           YPYTPDGNRE----FMDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIR
Rv0940c|M.tuberculosis_H37Rv        YPYTPDGNRE----FMDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIR
MAV_2247|M.avium_104                YPYTRDGQRR----WQPFTDWPDPWVLIGALAQVTTRLRFVNTVYIPAMR
Mvan_3595|M.vanbaalenii_PYR-1       YPYTKDGQRR----WEAFTDWPDPWVMIGAIALATTRLRFVTTVYLPAMR
MMAR_1586|M.marinum_M               YPYSEDGVIA----IPPQADWLDPMIALSFAAAASSRITVATGVLLLPEH
MUL_3448|M.ulcerans_Agy99           YPYSEDGVIA----IPPQADWLDPMIALSFAAASSSRITVATGVLLLPEH
MSMEG_2811|M.smegmatis_MC2_155      YPYSADGRIA----VAADADWLDPMIALSFAAAATSTIRIATGVLLLPEH
Mflv_4839|M.gilvum_PYR-GCK          HPYRDDGEIP----ASAQTDWLDPLIALSFAAAATNRIELATGVLVLPER
MAB_0366|M.abscessus_ATCC_1997      YPYSPTGQSH----LPDDIDIPDPLELLSFVAAATTTLGLSTGVLVLPDH
TH_4465|M.thermoresistible__bu      HPTSGTRQHHSGPLVAERTELIDPWAVHAAIAAVTTGIKLGTAVYVAALR
MLBr_00348|M.leprae_Br4923          DAVFTGEAWG-----------SDAYTPLAWWGSSTQRVRLGTSVVQLSAR
                                     .                    :.    .  .  :  : .   *   . :

Mb0965c|M.bovis_AF2122/97           PPALVAKQAGSLAALIGNRVGLGVGTSPWPEDYELMGVPFAKRGKRIDEC
Rv0940c|M.tuberculosis_H37Rv        PPALVAKQAGSLAALIGNRVGLGVGTSPWPEDYELMGVPFAKRGKRIDEC
MAV_2247|M.avium_104                NPYSAAKAIGTAAVLASGRVELGVGVGWCREEFALMGERFEARGKRTDEI
Mvan_3595|M.vanbaalenii_PYR-1       DPYSAAKAIGTAAVLAGGRLELGVGVGWCREEFELLGQQFERRGRRTDEM
MMAR_1586|M.marinum_M               NPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRAGRTAEY
MUL_3448|M.ulcerans_Agy99           NPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRVGRTAEY
MSMEG_2811|M.smegmatis_MC2_155      NPVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEALGVPFARRGARTAEY
Mflv_4839|M.gilvum_PYR-GCK          NPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASRGARLAEY
MAB_0366|M.abscessus_ATCC_1997      HPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRAADEA
TH_4465|M.thermoresistible__bu      HPLHTARTTITVQELSGGRVVFGVGVGWLEEEFDAFDVPFRTRVSRTEEC
MLBr_00348|M.leprae_Br4923          TPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREY
                                     *   *    :   :  .*  :  * .         .  *        * 

Mb0965c|M.bovis_AF2122/97           IEIVRGLTTGD-YFEFHGEFYDIP--KTKMT----------PAPTQPIPI
Rv0940c|M.tuberculosis_H37Rv        IEIVRGLTTGD-YFEFHGEFYDIP--KTKMT----------PAPTQPIPI
MAV_2247|M.avium_104                IELMRALWAPG-WTEFEGEFYSAP--RLEMQ----------PTP-PPIPV
Mvan_3595|M.vanbaalenii_PYR-1       LELMKALWSPG-WTEFSGEFYTAP--RMEME----------PTP-PPIPI
MMAR_1586|M.marinum_M               VAAMRTLWRDD-LASFTGEFVRFDSVRVNPK----------PVRDRRVPV
MUL_3448|M.ulcerans_Agy99           VAAMRTLWRDD-LASFTGEFVRFDSVRVNPK----------PVRDRRVPV
MSMEG_2811|M.smegmatis_MC2_155      VEAMRTLWRQD-VADFTGEFAAFDAVRLHPK----------PSAG-SIPI
Mflv_4839|M.gilvum_PYR-GCK          VGAMRTLWRDD-DASFAGRYVAFDGVRANPK----------PQGR-SIPV
MAB_0366|M.abscessus_ATCC_1997      IAVMRALWSTDGPTSHDGEFYSFRNAYSYPK----------PVRPQGVPL
TH_4465|M.thermoresistible__bu      LAILRAAWRGE-PFSHHGRHFRIDRVQVHSR----------PVD---IPV
MLBr_00348|M.leprae_Br4923          IDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPI
                                    :  ::            *..                           :*:

Mb0965c|M.bovis_AF2122/97           LVGGHADAALRRAARA-DGWMHG-GGDPDELDRLIARVKRLREEAGK---
Rv0940c|M.tuberculosis_H37Rv        LVGGHADAALRRAARA-DGWMHG-GGDPDELDRLIARVKRLREEAGK---
MAV_2247|M.avium_104                YVGGLSDIALRRAARS-DGWIGD-LIKTERAIEAVGRLRELRAENGL---
Mvan_3595|M.vanbaalenii_PYR-1       YVGGLSDIALRRAARH-DGWIGD-LITTDKALERIATLRGLRAENGL---
MMAR_1586|M.marinum_M               MVGGNSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGR---
MUL_3448|M.ulcerans_Agy99           MVGGNSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGR---
MSMEG_2811|M.smegmatis_MC2_155      IVGGNGDRALARVASWGDGWYGFNLDGVAAVGERMDMLRRLCARAGR---
Mflv_4839|M.gilvum_PYR-GCK          VLGGNSDAALRRVAEWGDGWYGFDLADVEEAAFRASKLRSMCREFGR---
MAB_0366|M.abscessus_ATCC_1997      YIGGHSKAAARRAGRLGSGFQPLGLVG-DDLTAAVGVMRAAAVDAGR---
TH_4465|M.thermoresistible__bu      VLGGNGPKALARAATLGDGWFTSGTPEFDDALRMVREIRRVREQHGRPGP
MLBr_00348|M.leprae_Br4923          MLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSR
                                     :*. .      ..   .*:                         .    

Mb0965c|M.bovis_AF2122/97           -------------------TSP--FEIHVISLDGFTVDGVKRLEDKGVTD
Rv0940c|M.tuberculosis_H37Rv        -------------------TSP--FEIHVISLDGFTVDGVKRLEDKGVTD
MAV_2247|M.avium_104                -------------------TMDD-FTILTPLTDAFTTADYRRAEDAGITG
Mvan_3595|M.vanbaalenii_PYR-1       -------------------DMHG-FEVITPLTDAFTAEHYERAEAGGITG
MMAR_1586|M.marinum_M               -------------------NRD--ELRLSVALRCPQPCDVDALAELGIDE
MUL_3448|M.ulcerans_Agy99           -------------------NRD--ELRLSVALRCPQPCDVDALAELGIDE
MSMEG_2811|M.smegmatis_MC2_155      -------------------DVD--DLHCAVALQAPAVGDIPALVDLGVDE
Mflv_4839|M.gilvum_PYR-GCK          -------------------DPT--ELKLSVALHDPVPADAVRLADAGIDE
MAB_0366|M.abscessus_ATCC_1997      -------------------DPRGLDLVLGHGLHRVDQAALDQAAHAGAGR
TH_4465|M.thermoresistible__bu      FTCYVRIPSVDEVGRYRDHDMTDLVLWADTVWQGRTLDEKRDRLAAAADR
MLBr_00348|M.leprae_Br4923          ----------------EDFEICASAQIVVTEDRAAAFAGIKPFLALYMGG
                                                                                      

Mb0965c|M.bovis_AF2122/97           VIVGFRVPYTMGPDTEPLQTKIRNLEMFAENVIAKV--------------
Rv0940c|M.tuberculosis_H37Rv        VIVGFRVPYTMGPDTEPLQTKIRNLEMFAENVIAKV--------------
MAV_2247|M.avium_104                IIT-MPWMFYAGPQAS-LDDKIDGMQRFRKDLALDG--------------
Mvan_3595|M.vanbaalenii_PYR-1       IIT-MPWMFYSGPDAS-LPDKVDGMRRFRKDLGLD---------------
MMAR_1586|M.marinum_M               LVLVETPPEAADAAQNWVSALAERWLSTVWVR------------------
MUL_3448|M.ulcerans_Agy99           LVLVETPPEAADAAQNWVSALAERWLSTVWVR------------------
MSMEG_2811|M.smegmatis_MC2_155      LVIVESPPQDPDVAADWVDALADRWITCI---------------------
Mflv_4839|M.gilvum_PYR-GCK          LVLVAGPPADPIAAEAWIADLAGQWMRVRT--------------------
MAB_0366|M.abscessus_ATCC_1997      MLLSASRRATTLEAVLEEMAGCATRLELGGPR------------------
TH_4465|M.thermoresistible__bu      LGLVSRSSGDPPAAAAGRSQRRRSGSALRMGDDVPRRVQNTGARSAGVRD
MLBr_00348|M.leprae_Br4923          MGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTM
                                    :                                                 

Mb0965c|M.bovis_AF2122/97           --------------------------------------------------
Rv0940c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2247|M.avium_104                --------------------------------------------------
Mvan_3595|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_1586|M.marinum_M               --------------------------------------------------
MUL_3448|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4465|M.thermoresistible__bu      TRPQNSRAGANGARTARDEHRGEVSLLRPLKAAESVARMIVDEIKTKGLQ
MLBr_00348|M.leprae_Br4923          IVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF----------
                                                                                      

Mb0965c|M.bovis_AF2122/97           --------------------------------------------------
Rv0940c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2247|M.avium_104                --------------------------------------------------
Mvan_3595|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_1586|M.marinum_M               --------------------------------------------------
MUL_3448|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4465|M.thermoresistible__bu      PGDSLPLEATMLKQYGVSRESLREGLRLLEVQGMISIRRGPGGGPVVGTV
MLBr_00348|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0965c|M.bovis_AF2122/97           --------------------------------------------------
Rv0940c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2247|M.avium_104                --------------------------------------------------
Mvan_3595|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_1586|M.marinum_M               --------------------------------------------------
MUL_3448|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4465|M.thermoresistible__bu      DAGHLGRVSALFYNMADATYEELLEAWVWAEGELAERAARNPDAQLRSAR
MLBr_00348|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0965c|M.bovis_AF2122/97           --------------------------------------------------
Rv0940c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2247|M.avium_104                --------------------------------------------------
Mvan_3595|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_1586|M.marinum_M               --------------------------------------------------
MUL_3448|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4465|M.thermoresistible__bu      MTPYLTDHDGSAEGLAPYLEGHTAFHRAVADLSNNRVLALSLQTYGQIVS
MLBr_00348|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0965c|M.bovis_AF2122/97           --------------------------------------------------
Rv0940c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2247|M.avium_104                --------------------------------------------------
Mvan_3595|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_1586|M.marinum_M               --------------------------------------------------
MUL_3448|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997      --------------------------------------------------
TH_4465|M.thermoresistible__bu      HHVAVLSDPRSLRDVLVDEHRHIAEAVISGHARRARALMRSHLEGVTAFV
MLBr_00348|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0965c|M.bovis_AF2122/97           ---------------
Rv0940c|M.tuberculosis_H37Rv        ---------------
MAV_2247|M.avium_104                ---------------
Mvan_3595|M.vanbaalenii_PYR-1       ---------------
MMAR_1586|M.marinum_M               ---------------
MUL_3448|M.ulcerans_Agy99           ---------------
MSMEG_2811|M.smegmatis_MC2_155      ---------------
Mflv_4839|M.gilvum_PYR-GCK          ---------------
MAB_0366|M.abscessus_ATCC_1997      ---------------
TH_4465|M.thermoresistible__bu      RENIPVPLDQPIEWL
MLBr_00348|M.leprae_Br4923          ---------------