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SKPTKQIHLAAHFPGVNNTTVWSDPASGSHIDFASFVHFAQTAERGKFDFMFLAEGLRLREQGGAIYDLD VVGRPDTFTVLAALAAVTDRLGLTGTINSTFNEPYEVARQFASLDHLSDGRAAWNVVTSWDAFTGENFRR GGFLPEHQRYERAESFLAAAHTLFDSWRGDEIIADKATGVFLSDPTAGEFSYHNDHFDISGRFNVPRSPQ GRPVIFQAGDSDHGREFAAAAADAIFSRHGTLEAGQQFFADVKGRLAKYGRRHSDLLILPAATFVLGDTD AEAADIAHEVRLAQVSPATAIKFLEQLWNRDLSDHDPDGPLPSVDPVVGENTIAKGRASVRMYRDPIATA NEWRAKAEAENLTTRELIIEVTGRQNFIGSPTTVAEQIDHLVQSDASDGFILVPHVTPGGLDPFVDKVVP LLQERGVFRTEYEGTTLRDHLDLAHPDRGAEPAAATG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2175 | - | - | 100% (458) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_1162 | - | 5e-80 | 37.04% (467) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_4552 | ssuD | 2e-65 | 35.41% (449) | nitrilotriacetate monooxygenase component A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 4e-06 | 27.70% (148) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0250 | - | 2e-45 | 29.77% (440) | hypothetical protein Mflv_0250 |
| M. tuberculosis H37Rv | Rv1855c | - | 5e-06 | 27.70% (148) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4232c | - | 1e-148 | 60.22% (445) | putative oxygenase |
| M. marinum M | MMAR_0703 | - | 1e-156 | 60.23% (440) | FMNH2-utilizing oxygenase |
| M. avium 104 | MAV_2048 | - | 1e-165 | 65.63% (451) | fmnh2-utilizing oxygenase |
| M. thermoresistible (build 8) | TH_4079 | - | 6e-72 | 37.86% (420) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_3024 | - | 1e-06 | 30.50% (141) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 3e-68 | 35.73% (445) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0703|M.marinum_M -------------MIRKPVHLAAHFPGVNNTTVWADPGAG---SQIEFES
MAV_2048|M.avium_104 -------MTTRKARRRKQIHLGAHFPGVNNTTVWSDPSAG---SQIAFES
MAB_4232c|M.abscessus_ATCC_199 MSNPADAVRTREGKDRKPVHLAAHFPGVNNTTVWSDPASG---SQIDFDS
MSMEG_2175|M.smegmatis_MC2_155 -----------MSKPTKQIHLAAHFPGVNNTTVWSDPASG---SHIDFAS
TH_4079|M.thermoresistible__bu ------------LPETRLSG------------------------ITDIDH
Mvan_6020|M.vanbaalenii_PYR-1 ----------MMHLITWLMGNSYHAAGWRHQLAWERT-------AMRLDV
Mflv_0250|M.gilvum_PYR-GCK -------MTDSAKRKAHLLGFVQHGVMNHASTMWAHPRDKVGYHWSRPEY
Mb1886c|M.bovis_AF2122/97 ----------MTIRLGLQIPNFSYGTG----------------VEKLFPS
Rv1855c|M.tuberculosis_H37Rv ----------MTIRLGLQIPNFSYGTG----------------VEKLFPS
MUL_3024|M.ulcerans_Agy99 ----------MAIRLGFQIPSFSYGTG----------------VDKLFPS
MMAR_0703|M.marinum_M FVHLARTAERGLFDFFFLAEGLRLREHRG-----RIHDLDVVGRPDTFTL
MAV_2048|M.avium_104 FVHLARTAERGLFDFFFLAEGLRLREHRG-----KIHDLDVVGRPDTFTV
MAB_4232c|M.abscessus_ATCC_199 FVHLARTAERGLFDFFFLAEGLRLREHRE-----RIYDLDVVGRPDTFTV
MSMEG_2175|M.smegmatis_MC2_155 FVHFAQTAERGKFDFMFLAEGLRLREQGG-----AIYDLDVVGRPDTFTV
TH_4079|M.thermoresistible__bu YLELARIAERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTL
Mvan_6020|M.vanbaalenii_PYR-1 LIEIAKIAEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTL
Mflv_0250|M.gilvum_PYR-GCK WRDLGRTMERGLFDAMFIADELAPYTTYKGSSDPVVKFAGQCPVHEPASV
Mb1886c|M.bovis_AF2122/97 VIAQAREAEAAGYDSLFVMDHFYQLPMLG---------TPDQPMLEAYTA
Rv1855c|M.tuberculosis_H37Rv VIAQAREAEAAGYDSLFVMDHFYQLPMLG---------TPDQPMLEAYTA
MUL_3024|M.ulcerans_Agy99 VIAQAREAEAAGFDSLFLMDHFYQLPMLG---------TPDQPMLEAYTA
.: * . * :*. : :. :
MMAR_0703|M.marinum_M LAALAGVTDRIGLTGTIN-TTFNEPFEVARQFATLDHLSEGRAGWNIVTS
MAV_2048|M.avium_104 LAALAAVTERLGLAGTIN-TTFNEPYEVARQFATLDHLSDGRAAWNMVTS
MAB_4232c|M.abscessus_ATCC_199 LAALGAVTERLGLVGTIN-TTFNEPFNVARQFASLDHLSDGRAGWNMVTS
MSMEG_2175|M.smegmatis_MC2_155 LAALAAVTDRLGLTGTIN-STFNEPYEVARQFASLDHLSDGRAAWNVVTS
TH_4079|M.thermoresistible__bu VTALSTATTHIGLVATAS-TTYTEPYGLARRFATLDHVSRGRAGWNIVTT
Mvan_6020|M.vanbaalenii_PYR-1 MAAISQHTKHIGLVGTAS-TTYESPWVVARRFASLDHLSNGRASWNVVTG
Mflv_0250|M.gilvum_PYR-GCK VPIVGAFTKHLGIGITLS-TSFVPPYMMARQLSTLDHLTGGRVGWNIVTS
Mb1886c|M.bovis_AF2122/97 LGALATATERLQLGALVTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAG
Rv1855c|M.tuberculosis_H37Rv LGALATATERLQLGALVTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAG
MUL_3024|M.ulcerans_Agy99 LGALATATERLQLGTLVTGNTYRNPALLAKIITTLDVVSAGRAVLGIGAG
: :. * :: : . .:: * :*: :::** :: **. .: :
MMAR_0703|M.marinum_M SDAFTGANFRRGGYLDHADRYQRAEEFLTVARKFWDSWAPGAVLADIENG
MAV_2048|M.avium_104 SDAFTGENFRRGGFLAHADRYRRAEEFITVARKFWDSWSPGAVIADVDAG
MAB_4232c|M.abscessus_ATCC_199 SDAFTGENFRRGGFLDHADRYRRAEEFITVARKFWDSWDAAGEPLPVN--
MSMEG_2175|M.smegmatis_MC2_155 WDAFTGENFRRGGFLPEHQRYERAESFLAAAHTLFDSWRGDEIIADKATG
TH_4079|M.thermoresistible__bu ANAAAAANFGRPAHPDPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAP
Mvan_6020|M.vanbaalenii_PYR-1 SNPGDSENFGLAHHPDRDSRYARAEEFVSACKALWNSWDEDAFVERKDTG
Mflv_0250|M.gilvum_PYR-GCK YSKSEFQAMGKENLTPRDKRYEVVEEYMQLLYQLWDSWDDDAIVYDRDNG
Mb1886c|M.bovis_AF2122/97 WFELEHRQLG-FEFGTFSDRFNRLEEALQILEPMVKGERP----------
Rv1855c|M.tuberculosis_H37Rv WFELEHRQLG-FEFGTFSDRFNRLEEALQILEPMVKGERP----------
MUL_3024|M.ulcerans_Agy99 WFELEHRQLG-YEFGTFTDRFNRLEEALQILDPIIKGERP----------
: *: :. : : ..
MMAR_0703|M.marinum_M DYVDPERIRSVEHSGPQFEVRGFATLPAGPQGHPVLLQAGDSEQGRAFGA
MAV_2048|M.avium_104 TYADPARIGVVEHHGRQFDVRGVASLPAGPQGHPVLLQAGDSSDGRDFGA
MAB_4232c|M.abscessus_ATCC_199 ------------HRGPQFTVRGVATAPASPQRHPVLLQAGDSADGRDFGA
MSMEG_2175|M.smegmatis_MC2_155 VFLSDPTAGEFSYHNDHFDISGRFNVPRSPQGRPVIFQAGDSDHGREFAA
TH_4079|M.thermoresistible__bu RFVDPDKIHAIDHRGEHFSVAGPLEVPRSPQGHPVLFQAGSSEPGKQLAA
Mvan_6020|M.vanbaalenii_PYR-1 QYLNARKVRVPDYKGRHLSVKGPLNVSRSPQGRPVLFHAGQSEGGRRLAA
Mflv_0250|M.gilvum_PYR-GCK VFADPAKVREVNFQGEFFQSRGRHFVAPSPQKRPVLWQAGSSAQGREFAS
Mb1886c|M.bovis_AF2122/97 -----------TFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAA
Rv1855c|M.tuberculosis_H37Rv -----------TFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAA
MUL_3024|M.ulcerans_Agy99 -----------TFSGSWYQAESAMAEPRYRDRIPILIGGGGEKKTFRIAA
. . . . : *:: .* . :.:
MMAR_0703|M.marinum_M RHADAMFTLHSSLRDGQRYYADVKGRARSYGRDPDQLKVFPAATFVIGDT
MAV_2048|M.avium_104 KHADALFTLHGSLEAGQRYYADVKSRAAAHGRDPEQLKVLPGATFALGDT
MAB_4232c|M.abscessus_ATCC_199 KHADALFTIHSSIPAGQKYYADVKARAVAHGRNPDQLKVFPGVTYVLGDT
MSMEG_2175|M.smegmatis_MC2_155 AAADAIFSRHGTLEAGQQFFADVKGRLAKYGRRHSDLLILPAATFVLGDT
TH_4079|M.thermoresistible__bu KYAEAIFTAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGGT
Mvan_6020|M.vanbaalenii_PYR-1 RHADCIFEAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGRT
Mflv_0250|M.gilvum_PYR-GCK RHAESVFGIFPTPKSMRAYATDIRTRASDAGRDPESVKLIYGLQTIIDRD
Mb1886c|M.bovis_AF2122/97 RFADHLN-IVAAVDELPRKMRALAARCDEAGRDRSTLQTSLLLTVMIDET
Rv1855c|M.tuberculosis_H37Rv RFADHLN-IVAAVDELPRKMRALAARCDEAGRDRSTLQTSLLLTVMIDET
MUL_3024|M.ulcerans_Agy99 HWADHLN-IVAALDELPRKMDAVAARCEEAGRDPSTLETSVMLTVVVDAK
*: : : : * * . : :.
MMAR_0703|M.marinum_M PDQAGEKARQISYQQVSGATAIAMLEQVWGRDLSDYDPDGPLPDIDP-IA
MAV_2048|M.avium_104 PAEAADNARHIREQQVSGPTAIAFLEQVWGVDLSAYDPDGPLPDVEP-VE
MAB_4232c|M.abscessus_ATCC_199 EQEAIEKAAYIRDQQVGPQTAIAYLEQVWGRDLSEYDPEGPLPDVDP-TG
MSMEG_2175|M.smegmatis_MC2_155 DAEAADIAHEVRLAQVSPATAIKFLEQLWNRDLSDHDPDGPLPSVDPVVG
TH_4079|M.thermoresistible__bu EEEARRIQRRLE-DLTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSD---
Mvan_6020|M.vanbaalenii_PYR-1 ESEAVELYSELN-SLISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS----
Mflv_0250|M.gilvum_PYR-GCK KGRANDRYAEFV-ENVQIESALGILSGHTGFDFSTLGLDDNVVDAD----
Mb1886c|M.bovis_AF2122/97 --------------------------------------------------
Rv1855c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3024|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0703|M.marinum_M DAAISQGRVR---HADPVAVARRYRERSQAENLSIRELVIAVT---SRQQ
MAV_2048|M.avium_104 NPTITRGRVR---HGDPKTVAETWRARARAENLSIRELIIEVT---SRQQ
MAB_4232c|M.abscessus_ATCC_199 DASITRGKAR---HGDPREIAAKYREIAEAKKLSIRELIKEVT---SRQQ
MSMEG_2175|M.smegmatis_MC2_155 ENTIAKGRASVRMYRDPIATANEWRAKAEAENLTTRELIIEVT---GRQN
TH_4079|M.thermoresistible__bu DPPAIHMQS----------RYALVRRLVSTENLTVRELLLRLSGGRGHRV
Mvan_6020|M.vanbaalenii_PYR-1 -APVVGGNS----------IRGQLDAIAKAEQLTVRQMYERVVPTMGNTA
Mflv_0250|M.gilvum_PYR-GCK ---VQGIRG----------LFDAILEAKDGAPVTVREAAQIYGVSMGAPV
Mb1886c|M.bovis_AF2122/97 --------------------------------LSPDAIPAEMS----GRV
Rv1855c|M.tuberculosis_H37Rv --------------------------------LSPDAIPAEMS----GRV
MUL_3024|M.ulcerans_Agy99 --------------------------------AKVERLPAETS----RRM
.
MMAR_0703|M.marinum_M FVGTPSHIADEIDRYVQADACDGFILVPHLT---PHGLDEFVDRVVPLLQ
MAV_2048|M.avium_104 FVGTPQQVAAEIDHYVQSDACDGFILVPHLT---PHGLDEFVDKVVPLLQ
MAB_4232c|M.abscessus_ATCC_199 FIGTPSQVATEVDRYIQADACDGFILVPHLT---PGGLDDFVDTVVPLLQ
MSMEG_2175|M.smegmatis_MC2_155 FIGSPTTVAEQIDHLVQSDASDGFILVPHVT---PGGLDPFVDKVVPLLQ
TH_4079|M.thermoresistible__bu FAGTPEQVADTIEEWFTTGAADGFNLIPPAL---PSSLTAFVDHVVPELQ
Mvan_6020|M.vanbaalenii_PYR-1 LIGTATQIADVMEEWYTTGACDGFVLGASIS---PFTLLLIRDELVPELQ
Mflv_0250|M.gilvum_PYR-GCK AVGTPADVADQMEQYLDEGDCNGFMMLATDT---PGCFNDMTELLVPELQ
Mb1886c|M.bovis_AF2122/97 VVGSPAQIADQIQAKVLDAGVDGLIINLAPHGYLPGVITTAAEALRPLLG
Rv1855c|M.tuberculosis_H37Rv VVGSPAQIADQIQAKVLDAGVDGLIINLAPHGYLPGVITTAAEALRPLLG
MUL_3024|M.ulcerans_Agy99 VTGSPAQIADQVQTKVLDTGIDGVIMNLSAHGHSPGLITTVAEALRPLLT
*:. :* :: :*. : * : : : * *
MMAR_0703|M.marinum_M ERGAFRTAYTGQTLRDHLGLAGLPS--------------
MAV_2048|M.avium_104 ERGSFRAEYRGITLREHLGLAPAPGSAPGADLESHCATG
MAB_4232c|M.abscessus_ATCC_199 ERGAFRAEYEHETLREHLGLDPISRASGDFRRETASA--
MSMEG_2175|M.smegmatis_MC2_155 ERGVFRTEYEGTTLRDHLDLAHPDRGA-----EPAAATG
TH_4079|M.thermoresistible__bu RRGLFRTEYTGTTLRDHLGLPRPRNRFTTGRPVAAAS--
Mvan_6020|M.vanbaalenii_PYR-1 RRGLFRRHYTGSTLRENLGLPPVDN-----SPFAT----
Mflv_0250|M.gilvum_PYR-GCK KRGRFRTRYPGTTLRESLREY------------------
Mb1886c|M.bovis_AF2122/97 V--------------------------------------
Rv1855c|M.tuberculosis_H37Rv V--------------------------------------
MUL_3024|M.ulcerans_Agy99 G--------------------------------------