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SNPADAVRTREGKDRKPVHLAAHFPGVNNTTVWSDPASGSQIDFDSFVHLARTAERGLFDFFFLAEGLRL REHRERIYDLDVVGRPDTFTVLAALGAVTERLGLVGTINTTFNEPFNVARQFASLDHLSDGRAGWNMVTS SDAFTGENFRRGGFLDHADRYRRAEEFITVARKFWDSWDAAGEPLPVNHRGPQFTVRGVATAPASPQRHP VLLQAGDSADGRDFGAKHADALFTIHSSIPAGQKYYADVKARAVAHGRNPDQLKVFPGVTYVLGDTEQEA IEKAAYIRDQQVGPQTAIAYLEQVWGRDLSEYDPEGPLPDVDPTGDASITRGKARHGDPREIAAKYREIA EAKKLSIRELIKEVTSRQQFIGTPSQVATEVDRYIQADACDGFILVPHLTPGGLDDFVDTVVPLLQERGA FRAEYEHETLREHLGLDPISRASGDFRRETASA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4232c | - | - | 100% (454) | putative oxygenase |
| M. abscessus ATCC 19977 | MAB_4125 | - | 5e-57 | 35.25% (451) | putative nitrilotriacetate monooxygenase |
| M. abscessus ATCC 19977 | MAB_3401 | - | 2e-44 | 30.88% (421) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0214 | - | 6e-54 | 45.30% (287) | fmnh2-utilizing oxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0703 | - | 0.0 | 73.00% (437) | FMNH2-utilizing oxygenase |
| M. avium 104 | MAV_2048 | - | 0.0 | 74.77% (444) | fmnh2-utilizing oxygenase |
| M. smegmatis MC2 155 | MSMEG_2175 | - | 1e-148 | 60.22% (445) | nitrilotriacetate monooxygenase component A |
| M. thermoresistible (build 8) | TH_4079 | - | 7e-73 | 38.35% (412) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 1e-08 | 27.84% (194) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_6020 | - | 1e-66 | 34.52% (449) | xenobiotic compound DszA family monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4079|M.thermoresistible__bu ------------LPETRLSG---------------------ITDIDHYLE
Mvan_6020|M.vanbaalenii_PYR-1 ----------MMHLITWLMGNSYHAAGWRHQLAW----ERTAMRLDVLIE
MAB_4232c|M.abscessus_ATCC_199 MSNPADAVRTREGKDRKPVHLAAHFPGVNNTTVWSDPASGSQIDFDSFVH
MMAR_0703|M.marinum_M -------------MIRKPVHLAAHFPGVNNTTVWADPGAGSQIEFESFVH
MAV_2048|M.avium_104 -------MTTRKARRRKQIHLGAHFPGVNNTTVWSDPSAGSQIAFESFVH
MSMEG_2175|M.smegmatis_MC2_155 -----------MSKPTKQIHLAAHFPGVNNTTVWSDPASGSHIDFASFVH
Mflv_0214|M.gilvum_PYR-GCK ----------MKAERSKHIHLGARLP-------------ASFDSWDSLVH
MUL_4507|M.ulcerans_Agy99 ----------MALLFHWFLPTYGDSRGLVAGGHGLPMSGNRPATLRYLNQ
.
TH_4079|M.thermoresistible__bu LARIAERGKLDAIFFADHPVLKGKTEFRPFDA---------LDPVTLVTA
Mvan_6020|M.vanbaalenii_PYR-1 IAKIAEEAKLDALFVADGNGVRNMDKVGLFEANTPSARPTVYDPVTLMAA
MAB_4232c|M.abscessus_ATCC_199 LARTAERGLFDFFFLAEG--LRLREHRERIYDLDVVGRP---DTFTVLAA
MMAR_0703|M.marinum_M LARTAERGLFDFFFLAEG--LRLREHRGRIHDLDVVGRP---DTFTLLAA
MAV_2048|M.avium_104 LARTAERGLFDFFFLAEG--LRLREHRGKIHDLDVVGRP---DTFTVLAA
MSMEG_2175|M.smegmatis_MC2_155 FAQTAERGKFDFMFLAEG--LRLREQGGAIYDLDVVGRP---DTFTVLAA
Mflv_0214|M.gilvum_PYR-GCK LARTAERGLFDFVLVDDG--ARRREQ-----------RS---DALTMLAA
MUL_4507|M.ulcerans_Agy99 IAAAAESNGFEAVLTPAG--------------------LWCEDAWLTTAM
:* ** :: .: *. :
TH_4079|M.thermoresistible__bu LSTATTHIGLVATASTTYTEPYGLARRFATLDHVSRGRAGWNIVTTANAA
Mvan_6020|M.vanbaalenii_PYR-1 ISQHTKHIGLVGTASTTYESPWVVARRFASLDHLSNGRASWNVVTGSNPG
MAB_4232c|M.abscessus_ATCC_199 LGAVTERLGLVGTINTTFNEPFNVARQFASLDHLSDGRAGWNMVTSSDAF
MMAR_0703|M.marinum_M LAGVTDRIGLTGTINTTFNEPFEVARQFATLDHLSEGRAGWNIVTSSDAF
MAV_2048|M.avium_104 LAAVTERLGLAGTINTTFNEPYEVARQFATLDHLSDGRAAWNMVTSSDAF
MSMEG_2175|M.smegmatis_MC2_155 LAAVTDRLGLTGTINSTFNEPYEVARQFASLDHLSDGRAAWNVVTSWDAF
Mflv_0214|M.gilvum_PYR-GCK LAAVTDRVGLVGTVDTGATEPFEVARRIATLDHLSDGRVGWHR-------
MUL_4507|M.ulcerans_Agy99 LVGTTKTLKFLVALRPGLVSPTLAAQMATTFQQQSGGRLLVNVVTGGEAH
: * : : : . .* *: ::::: * ** :
TH_4079|M.thermoresistible__bu AAANFGRPAHPDPEHRYSRADEFLQVALRLWDSWEDDAIVGDKQAPRFVD
Mvan_6020|M.vanbaalenii_PYR-1 DSENFGLAHHPDRDSRYARAEEFVSACKALWNSWDEDAFVERKDTGQYLN
MAB_4232c|M.abscessus_ATCC_199 TGENFRRGGFLDHADRYRRAEEFITVARKFWDSWDAAG-----------E
MMAR_0703|M.marinum_M TGANFRRGGYLDHADRYQRAEEFLTVARKFWDSWAPGAVLADIENGDYVD
MAV_2048|M.avium_104 TGENFRRGGFLAHADRYRRAEEFITVARKFWDSWSPGAVIADVDAGTYAD
MSMEG_2175|M.smegmatis_MC2_155 TGENFRRGGFLPEHQRYERAESFLAAAHTLFDSWRGDEIIADKATGVFLS
Mflv_0214|M.gilvum_PYR-GCK AGADVRR------------AGEFLAVARLFWDSWAEDAVLADHDAGRYVD
MUL_4507|M.ulcerans_Agy99 EQRAYGD--FLDKQQRYRRTGEFLHVVRQLWASG----------------
: .*: . :: *
TH_4079|M.thermoresistible__bu PDKIHAIDHRGEHFSVAGPLEVPRSPQGHPVLFQAGSSEPGKQLAAKYAE
Mvan_6020|M.vanbaalenii_PYR-1 ARKVRVPDYKGRHLSVKGPLNVSRSPQGRPVLFHAGQSEGGRRLAARHAD
MAB_4232c|M.abscessus_ATCC_199 P---LPVNHRGPQFTVRGVATAPASPQRHPVLLQAGDSADGRDFGAKHAD
MMAR_0703|M.marinum_M PERIRSVEHSGPQFEVRGFATLPAGPQGHPVLLQAGDSEQGRAFGARHAD
MAV_2048|M.avium_104 PARIGVVEHHGRQFDVRGVASLPAGPQGHPVLLQAGDSSDGRDFGAKHAD
MSMEG_2175|M.smegmatis_MC2_155 DPTAGEFSYHNDHFDISGRFNVPRSPQGRPVIFQAGDSDHGREFAAAAAD
Mflv_0214|M.gilvum_PYR-GCK PDRIRAVEHRGPHFDVRGFATLPRPPQRHPVLVQDDDSEDGTAFAAAHAD
MUL_4507|M.ulcerans_Agy99 ----QPVTFEGEHIHVH-QAQLGRLPDPPPPVFFGGSSESAGAVAARYAD
. . :: : *: * :. ..* . ..* *:
TH_4079|M.thermoresistible__bu AIFTAQPTVEEARQFYADVKARVRQHGRDPDRVHILPGLSAIIGGTEEEA
Mvan_6020|M.vanbaalenii_PYR-1 CIFEAAASVEAAREFYADLKRRRVEIGGEPDHLRIIVSVAVYLGRTESEA
MAB_4232c|M.abscessus_ATCC_199 ALFTIHSSIPAGQKYYADVKARAVAHGRNPDQLKVFPGVTYVLGDTEQEA
MMAR_0703|M.marinum_M AMFTLHSSLRDGQRYYADVKGRARSYGRDPDQLKVFPAATFVIGDTPDQA
MAV_2048|M.avium_104 ALFTLHGSLEAGQRYYADVKSRAAAHGRDPEQLKVLPGATFALGDTPAEA
MSMEG_2175|M.smegmatis_MC2_155 AIFSRHGTLEAGQQFFADVKGRLAKYGRRHSDLLILPAATFVLGDTDAEA
Mflv_0214|M.gilvum_PYR-GCK AVITPHAGLEARQRYVADVRTKVAAAGRNPDSVTVFALTKLSP-------
MUL_4507|M.ulcerans_Agy99 TYLTWGEPLSAVGKKIDWIRGLAADHGR---ALSYGLRIHVITRDTAEEA
: : . :: * :
TH_4079|M.thermoresistible__bu RRIQRRLED-LTVPDYGLEQLSRIVGYRVGRDDLDRRLQFGSD--DPPAI
Mvan_6020|M.vanbaalenii_PYR-1 VELYSELNS-LISPDLGVDFLAKAVSEDLTGYPVDGPMPDLS----APVV
MAB_4232c|M.abscessus_ATCC_199 IEKAAYIRDQQVGPQTAIAYLEQVWGRDLSEYDPEGPLPDVDP-TGDASI
MMAR_0703|M.marinum_M GEKARQISYQQVSGATAIAMLEQVWGRDLSDYDPDGPLPDIDP-IADAAI
MAV_2048|M.avium_104 ADNARHIREQQVSGPTAIAFLEQVWGVDLSAYDPDGPLPDVEP-VENPTI
MSMEG_2175|M.smegmatis_MC2_155 ADIAHEVRLAQVSPATAIKFLEQLWNRDLSDHDPDGPLPSVDPVVGENTI
Mflv_0214|M.gilvum_PYR-GCK --------------------------------------------------
MUL_4507|M.ulcerans_Agy99 WRVADRLLAGIDPADIERMQANLARSESEGQRRMAELHG-----------
TH_4079|M.thermoresistible__bu HMQSRY-----------ALVRRLVSTENLTVRELLLRLSGGRGHRVFAGT
Mvan_6020|M.vanbaalenii_PYR-1 GGNSIR-----------GQLDAIAKAEQLTVRQMYERVVPTMGNTALIGT
MAB_4232c|M.abscessus_ATCC_199 TRGKAR---HGDPREIAAKYREIAEAKKLSIRELIKEVT---SRQQFIGT
MMAR_0703|M.marinum_M SQGRVR---HADPVAVARRYRERSQAENLSIRELVIAVT---SRQQFVGT
MAV_2048|M.avium_104 TRGRVR---HGDPKTVAETWRARARAENLSIRELIIEVT---SRQQFVGT
MSMEG_2175|M.smegmatis_MC2_155 AKGRASVRMYRDPIATANEWRAKAEAENLTTRELIIEVT---GRQNFIGS
Mflv_0214|M.gilvum_PYR-GCK ------------------------------------------------GS
MUL_4507|M.ulcerans_Agy99 -----------------GVLDQLEIAPNLWAGVGLVRGG---AGTALVGS
*:
TH_4079|M.thermoresistible__bu PEQVADTIEEWFTTGAADGFNLIPPALPSSLTAFVDHVVPELQRRGLFRT
Mvan_6020|M.vanbaalenii_PYR-1 ATQIADVMEEWYTTGACDGFVLGASISPFTLLLIRDELVPELQRRGLFRR
MAB_4232c|M.abscessus_ATCC_199 PSQVATEVDRYIQADACDGFILVPHLTPGGLDDFVDTVVPLLQERGAFRA
MMAR_0703|M.marinum_M PSHIADEIDRYVQADACDGFILVPHLTPHGLDEFVDRVVPLLQERGAFRT
MAV_2048|M.avium_104 PQQVAAEIDHYVQSDACDGFILVPHLTPHGLDEFVDKVVPLLQERGSFRA
MSMEG_2175|M.smegmatis_MC2_155 PTTVAEQIDHLVQSDASDGFILVPHVTPGGLDPFVDKVVPLLQERGVFRT
Mflv_0214|M.gilvum_PYR-GCK PAKVADEMDLHVRSGACDGFLLVPDPTPHGLDEFVDDVVPLLQERGSLRT
MUL_4507|M.ulcerans_Agy99 HQEVAERIIEYARLGISH-FILSGYPHLEEAYWFGEGVLPILERKRLWHR
:* : . .. * * : : ::* *:.: :
TH_4079|M.thermoresistible__bu EYTGTTLRDHLGLPRPRNRFTTGRPVAAAS--
Mvan_6020|M.vanbaalenii_PYR-1 HYTGSTLRENLGLPPVDN-----SPFAT----
MAB_4232c|M.abscessus_ATCC_199 EYEHETLREHLGLDPISRASGDFRRETASA--
MMAR_0703|M.marinum_M AYTGQTLRDHLGLAGLPS--------------
MAV_2048|M.avium_104 EYRGITLREHLGLAPAPGSAPGADLESHCATG
MSMEG_2175|M.smegmatis_MC2_155 EYEGTTLRDHLDLAHPDRGA-----EPAAATG
Mflv_0214|M.gilvum_PYR-GCK GYCGHTLRDHLAQPAL----------------
MUL_4507|M.ulcerans_Agy99 PHGSSPHSAALPVAHSSVN-------------
: . *