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M. smegmatis MC2 155 MSMEG_4828 (-)

annotation: alcohol dehydrogenase, zinc-binding
coordinates: 4924779 - 4925753
length: 324

VRAAVCPRYGPPEVVRVEELPVPELGPDQVRVRVGAAAVNFPDVLLVADRYQATVPVPFVPGSEFAGVVT
ETADGVTDFAVGDRVVGTGMHGAFAEEVCVDASCLQRAVERLDDRGAAASGVAHRTAFHALRSVARVSTG
DDVVVLGAGGGVGLAAVQIAAALGARVTAVASSSEKLDAAARYGAHHLVDHTAGPLRAALRDAVPDGADA
VLDPVGGDLSEPALRALRRGGRFVTIGFASGAIPRIPLNLVLVKGVQILGFAFQDVPPEEFARNESELGE
LLASGAVTPHIGAVYPLVEVAAALRHVAEGRAVGKVVLDVSRVR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4828--100% (324)alcohol dehydrogenase, zinc-binding
M. smegmatis MC2 155MSMEG_2033-6e-4538.11% (328) oxidoreductase, zinc-binding dehydrogenase family protein
M. smegmatis MC2 155MSMEG_0097-3e-3937.16% (296) oxidoreductase, zinc-binding dehydrogenase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0154-5e-4337.97% (295) putative quinone oxidoreductase (NADPH:quinone oxidoreductase)
M. gilvum PYR-GCKMflv_2449-1e-12571.56% (320) alcohol dehydrogenase
M. tuberculosis H37RvRv0149-5e-4337.97% (295) quinone oxidoreductase
M. leprae Br4923MLBr_00139mas3e-3231.33% (316) putative mycocerosic synthase
M. abscessus ATCC 19977MAB_4603c-2e-4335.16% (310) oxidoreductase
M. marinum MMMAR_5313-6e-8552.63% (323) quinone oxidoreductase
M. avium 104MAV_0308-1e-8452.47% (324) alcohol dehydrogenase, zinc-binding
M. thermoresistible (build 8)TH_3212-1e-11968.22% (321) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein
M. ulcerans Agy99MUL_4387-2e-8452.47% (324) quinone oxidoreductase
M. vanbaalenii PYR-1Mvan_4202-1e-12369.78% (321) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDD
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          FYDPEPGVPGRSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLE
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          TSWEAIEQGGLDPASLAGSSTAVFTGLTHEDYLVLTTAAGGLASPYVVTG
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          LNNSVASGRISHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGESDLAL
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          AGGCAVLLEPHASVAASAQGMLSSTGRCKSFAADADGFVRSEGCAMVLLK
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          RLPDALRDGNRIFAMILGTATNQDGGTETLMMPSEDAQVAVYQAALAVAG
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          VEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHST
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          ASAGTVGLIKAILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWP
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          VGGYNTPKRVAVSSFGMSGTNVHVIVEEAPSEACAPDVPETSPGTGDATV
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          GRQLFMLSSTSIAALRETARQLATWVEEHQDSVVLSDLAYTLARGRAHRP
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          VRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSGQGSQWA
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          SMGVQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQP
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          SVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAARVI
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          CRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTV
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          IGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLAAALADI
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          APMTPKVPYYSATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAMEDGY
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          RVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLLADL
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          HSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTV
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          HPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEM
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          ALAAAVEVFGEAAEVRAIAFEQMLLLAAETPIDAIASVDAPGVINFVVQA
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          NQDGEKMRNATATLHAAEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAE
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          RGVQLGAAFAGLATAHTAEAESGTVLAEVALPASIRFQQSSYQIHPALLD
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          ACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYRPTRNARYCYTRLTKIE
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          PRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQLSERLLTIGWQ
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          QRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTN
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          LSWLIQDDPVVSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVR
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          HLVRIIRELAELEGELPRLFVVTRQAQIVQSGDAANLEQAGLRGLLRVIS
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          SEHPMLRTTLVDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLNPS
                                                                                      

Mb0154|M.bovis_AF2122/97            -----------------MKACVVKELSGPSGMVYTDIDEVSGDGGKVVID
Rv0149|M.tuberculosis_H37Rv         -----------------MKACVVKELSGPSGMVYTDIDEVSGDGGKVVID
MAB_4603c|M.abscessus_ATCC_199      -----------------MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVD
Mflv_2449|M.gilvum_PYR-GCK          -----------------MRAAMCREYGPPEVVRVEDVAEPVAGPGQIGVR
Mvan_4202|M.vanbaalenii_PYR-1       -----------------MRAAVCPQYGPPEVVRVEERPEPSAGPGQVVVR
TH_3212|M.thermoresistible__bu      -----------------MRAAVCTAHGPPEVVCIEERPAPGLLPGQVRVR
MSMEG_4828|M.smegmatis_MC2_155      -----------------MRAAVCPRYGPPEVVRVEELPVPELGPDQVRVR
MMAR_5313|M.marinum_M               -----------------MRAIVCNAYGPPEDLVLDEVPDPVPAPGQVLVR
MUL_4387|M.ulcerans_Agy99           -----------------MRAIVCDAYGPPEDLVLDEVPDPVPAPGQVLVR
MAV_0308|M.avium_104                -----------------MRAVVCRSYGTPEDLVLDEVPDPVPGPGQLLVR
MLBr_00139|M.leprae_Br4923          PLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPPGPGQLEVA
                                                              .  . :            . : : 

Mb0154|M.bovis_AF2122/97            VRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDAG-FHVGE
Rv0149|M.tuberculosis_H37Rv         VRAAGVCFPDLLLTKGEYQLKLTPPFVPGMETAGVVRSAPSDAG-FHVGE
MAB_4603c|M.abscessus_ATCC_199      VKAAGVCFPDYLMTKGEYQLKMEPPFVPGIETAGVVRSAPEGSG-IKPGD
Mflv_2449|M.gilvum_PYR-GCK          VDAAAVNFPDVLLVAGTYQISVPPPFVPGSEFAGVVDEIGPGTEGFTIGD
Mvan_4202|M.vanbaalenii_PYR-1       VEAAAVNFPDVLLVADSYQVSVAPPFVPGSEFTGVVDEIGPHTTGFTVGE
TH_3212|M.thermoresistible__bu      VAAAGVNFPDVLLIAGRYQLPVPPPFVPGSEFAGVIVETCGDTGGFAVGD
MSMEG_4828|M.smegmatis_MC2_155      VGAAAVNFPDVLLVADRYQATVPVPFVPGSEFAGVVTETADGVTDFAVGD
MMAR_5313|M.marinum_M               VRAAAVNFPDVLFIAGKYQIKIPPPFIPGNEIAGEVVSVGAGVT-LVPGQ
MUL_4387|M.ulcerans_Agy99           VRAVAVNFPDVLFIAGKYQIKIPPPFVPGNEIAGEVVGAGAGVI-LVPGQ
MAV_0308|M.avium_104                VRAAAVNFPDVLFIAGKYQVKIPPPFIPGNEIAGEVIAAGEGAR-FLPGQ
MLBr_00139|M.leprae_Br4923          VSMSSINFADVLIAFGRFPIIDDRDPQLGMDFVGVVTAVGEGVTGHQIGD
                                    *   .: *.* *:  . :          * : .* :            *:

Mb0154|M.bovis_AF2122/97            RVSAFGVLGGYAEQIAVPVANVVRSPVELDDAGAVSLLVNYNTMYFALAR
Rv0149|M.tuberculosis_H37Rv         RVSAFGVLGGYAEQIAVPVANVVRSPVELDDAGAVSLLVNYNTMYFALAR
MAB_4603c|M.abscessus_ATCC_199      RVMAFNFIGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYAR
Mflv_2449|M.gilvum_PYR-GCK          RVSGTAMFGAFAERTVVDAAALAPIPDGVDARTAAAFGVAYRTAYHTLRS
Mvan_4202|M.vanbaalenii_PYR-1       RVAGTGMFGAFAERVVADAAGLTPVPDGVDARTAAAFGVAHRTAYHALRS
TH_3212|M.thermoresistible__bu      PVTGTVLHGAFATEVAVPAAGLTRVPDGVPLRTAAAFGVAHRTAYHALRS
MSMEG_4828|M.smegmatis_MC2_155      RVVGTGMHGAFAEEVCVDASCLQRAVERLDDRGAAASGVAHRTAFHALRS
MMAR_5313|M.marinum_M               RVFGT-TFGAFAELALLDGAAAEPIPDDADFASAAAFGVTYRTAYHALRS
MUL_4387|M.ulcerans_Agy99           RVFGT-TFGAFAELALLDGAAAQPIPDDADFASAAAFGVTYRTAYHALRS
MAV_0308|M.avium_104                RVAGT-TFGAFAEQALLDADQAEPIPDDADFASAAAFGVTYRTAYHALRS
MLBr_00139|M.leprae_Br4923          RVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQAITAATAHATAWYGLND
                                     * .    * :                      * :  . : * :.    

Mb0154|M.bovis_AF2122/97            RAALRPGDTVLVLGAAGGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVAS
Rv0149|M.tuberculosis_H37Rv         RAALRPGDTVLVLGAAGGVGTAAVQIAKAMQAGKVIAMVHREGAIDYVAS
MAB_4603c|M.abscessus_ATCC_199      RGQLRAGETVLVLGAAGGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKS
Mflv_2449|M.gilvum_PYR-GCK          VARVSEGDELVVLGAGGGVGLAAVQLGVALGA-NVTAVASSAEKLAAAAE
Mvan_4202|M.vanbaalenii_PYR-1       TARLSAGDELVVLGAGGGVGLATVQLGVALGA-RVTAVASSNEKLAVAGG
TH_3212|M.thermoresistible__bu      MARLTAGQELIVLGAGSGVGLAAVQLGVALGA-QVTAVASTAEKLAVAGA
MSMEG_4828|M.smegmatis_MC2_155      VARVSTGDDVVVLGAGGGVGLAAVQIAAALGA-RVTAVASSSEKLDAAAR
MMAR_5313|M.marinum_M               VAQVSQGDWVVVLGAAGGVGLAAVDLAVAMGA-RVLAAASSPEKLGLCRQ
MUL_4387|M.ulcerans_Agy99           VAQVSQGDWVVVLGAAGGVGLAAVDLAVAMGA-RVLAAASSPEKLGLCRQ
MAV_0308|M.avium_104                TAGVTAGDWVVVLGAAGGVGLAAVDLAVAMQA-RVLAAASSPEKLELCRR
MLBr_00139|M.leprae_Br4923          LAGIKVGDKVLIHSATGGVGQAAISIARAKGA-EIFATAGNPTKRAMLHD
                                     . :  *: ::: .* .*:* *::.:. .  * .: * .           

Mb0154|M.bovis_AF2122/97            LGADVVLPLT-EGWAQQVRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDG
Rv0149|M.tuberculosis_H37Rv         LGADVVLPLT-EGWAQQVRDHTYGQGVDIVVDPIGGPTFDDALGVLAIDG
MAB_4603c|M.abscessus_ATCC_199      VGADIVLPLE-EGWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEG
Mflv_2449|M.gilvum_PYR-GCK          YGAAHLVDHR-EQDLRAALRTAVPDGADVVIDPVGGRLSEPALRSLGRGG
Mvan_4202|M.vanbaalenii_PYR-1       YGAATLINHR-DGELRQALRQAIPDGADVVVDPVGGDVSEPALRSLGRGG
TH_3212|M.thermoresistible__bu      HGAGRRICHR-DTDLRAALREVLPGGADAVIDPVGGDLSEPALRSLRRGG
MSMEG_4828|M.smegmatis_MC2_155      YGAHHLVDHT-AGPLRAALRDAVPDGADAVLDPVGGDLSEPALRALRRGG
MMAR_5313|M.marinum_M               RGAEAVVDYD-QEDLKLRIRELTGESARVVLDPVGGSYAEPALRGLARGG
MUL_4387|M.ulcerans_Agy99           RGAEAVVDYD-QEDLKLRIRELTGESARVVLDPVGGSYAEPALRGLARGG
MAV_0308|M.avium_104                RGAEATVDYD-REDLKTRIRDLTGDRARVVLDPVGGPYSEPALRGLARGG
MLBr_00139|M.leprae_Br4923          LGIEHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGG
                                     *             .          .  *::.: *     .:  *   *

Mb0154|M.bovis_AF2122/97            KLLLIGFAAGAVPTLKVNRLLVRNISVVGVGWGEYLNAVPGSAALFAWGL
Rv0149|M.tuberculosis_H37Rv         KLLLIGFAAGAVPTLKVNRLLVRNISVVGVGWGEYLNAVPGSAALFAWGL
MAB_4603c|M.abscessus_ATCC_199      RLLVVGFAAGGIPTIKVNRLLLRNASLIGVAWGEFLRTHADYLYETQAGL
Mflv_2449|M.gilvum_PYR-GCK          RFVTVGFASGEIPRIPLNLVLLKGVQVLGFQFQDVP---GDEFVRNDHEL
Mvan_4202|M.vanbaalenii_PYR-1       RFVSVGFASGVIPRIPLNLVLIKGVHVLGFQFQDVP---ADEFTRNEVEL
TH_3212|M.thermoresistible__bu      RFVTVGYASGVIPRIPLNLVLVKGVHILGFQFQDVA---PEEFTRNEDEL
MSMEG_4828|M.smegmatis_MC2_155      RFVTIGFASGAIPRIPLNLVLVKGVQILGFAFQDVP---PEEFARNESEL
MMAR_5313|M.marinum_M               MFVTLGYAAGSIPAIPLNLVMLKNLTIRGMEIRTFMGDYPNECARDVAEL
MUL_4387|M.ulcerans_Agy99           IFVTLGYAAGSIPAIPLNLVMLKNLTIRGMEIRTFMGDYPDECARDVAEL
MAV_0308|M.avium_104                TFVTLGYASGTIPAIPLNLVLLKDICVRGMEIRTFMTDRPDDAVRDLTEL
MLBr_00139|M.leprae_Br4923          RFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATV
                                     :: :* *            : :.  .  .                   :

Mb0154|M.bovis_AF2122/97            NQLVFLG-LRPPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP--------
Rv0149|M.tuberculosis_H37Rv         NQLVFLG-LRPPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP--------
MAB_4603c|M.abscessus_ATCC_199      EKLVAEG-MRPPVSARIPLSEGRQALQDFADGKVYGKMVLVP--------
Mflv_2449|M.gilvum_PYR-GCK          RALLSARRVTPHVGAVYPLEEVAAALRHVGEGRAIGKVLIDVPA------
Mvan_4202|M.vanbaalenii_PYR-1       RELLVSGRVKPHVGAVYSLDDTVAALRHVSDGRAIGKVVIDLS-------
TH_3212|M.thermoresistible__bu      GGFLVSGRARPHIGAVFPLSEAAAALRHVADGRAVGKVVIDLTD------
MSMEG_4828|M.smegmatis_MC2_155      GELLASGAVTPHIGAVYPLVEVAAALRHVAEGRAVGKVVLDVSRVR----
MMAR_5313|M.marinum_M               SQMFAAGKIRPHIGARFPLADTPAALRYVAERKVLGKVVIDVV-------
MUL_4387|M.ulcerans_Agy99           SQMFAAGKIRPHIGARFPLADTPAALRYVAERKVLGKVVIDVA-------
MAV_0308|M.avium_104                SQMFAAGTVRPYIGARFPLARTAAALRHVADRKVLGKVVIDVA-------
MLBr_00139|M.leprae_Br4923          FNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSV
                                      :       .      .*     *:: . :    **:::          

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          AVPPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAGCGRIVLTARSQPN
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          PKARQTIERLCAAGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHS
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          AAVVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLDWFCLFSSGA
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          ALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLA
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          EGGEIMITPDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEM
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          FSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVILRRTIDADR
                                                                                      

Mb0154|M.bovis_AF2122/97            --------------------------------------------------
Rv0149|M.tuberculosis_H37Rv         --------------------------------------------------
MAB_4603c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_2449|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4202|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3212|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4828|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_5313|M.marinum_M               --------------------------------------------------
MUL_4387|M.ulcerans_Agy99           --------------------------------------------------
MAV_0308|M.avium_104                --------------------------------------------------
MLBr_00139|M.leprae_Br4923          SFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLA
                                                                                      

Mb0154|M.bovis_AF2122/97            -----------------
Rv0149|M.tuberculosis_H37Rv         -----------------
MAB_4603c|M.abscessus_ATCC_199      -----------------
Mflv_2449|M.gilvum_PYR-GCK          -----------------
Mvan_4202|M.vanbaalenii_PYR-1       -----------------
TH_3212|M.thermoresistible__bu      -----------------
MSMEG_4828|M.smegmatis_MC2_155      -----------------
MMAR_5313|M.marinum_M               -----------------
MUL_4387|M.ulcerans_Agy99           -----------------
MAV_0308|M.avium_104                -----------------
MLBr_00139|M.leprae_Br4923          EEEGVAAPAAMVSPETP