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VRTATATSVAVIGMACRLPGGIDSPQRLWEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSVSRWGAF LDDVGGFDCDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGVFVGLTHGDYELLSADC GAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLTAVHQACRSLDDGESDLALAGGVVVTLE PRKSVSGSLQGMLSPTGRCHAFDEAADGFVSGEGCVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGRTVN IAAPSAQAQIAVYQQALAAAGVEASTVGMVEAHGTGTPVGDPVEYASLAAVYGTEGPCALTSVKTNFGHL QSASGPLGLMKTILALRHGVVPQNLHFCRLPDQLAEIDTELFVPQANTSWPDNTGQPRRAAVSSYGMSGT NVHAILEQAPVSEPAASGPELTPEAGGLALFPVSATSAEQLHVTAARLADWVDQNGNAGSRVSMRDLGYT LSCRRAHRPVRTVVTASSFDELSAALRDVAGDQIPYQPAVGHDDRGPVWVFSGQGSQWPGMGTELLVAEP VFAATVAAMEPVIARESGFSVTEAMSAPQTVSGIDRVQPTIFAVQVALAAALKSYGVRPGAIIGHSLGEA AAAVVAGALSLHDGLRVICRRSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTSTVVG GATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLAEVDPTAPEIPYYSATLWDPRERPS FTGEYWVENLRYTVRFAAAVQAALKDGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFG LRGFVADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSREDSHRSHTGAVQAVHPLLGAHVHLLEE PERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAYCEMALAAARTTLGELSEVRDIKFEQTLLLDEQTVVS SAATIAAPGILQFAVESHQEGEPARRASAMLHALEEMPQPPGYDTNALTAAHESSMSGEELRKMFNSLGI QYGPAFSGLVAVHTARGAVTTVLAEVALPGAIRSQQSAYASHPALLDACFQSVLVHPEVQKATVGGLMLP VGVRRLRNYHSTRSAHYCLARVTSSSRAGECEADLDVFDQAGTVLLTVEGLRLAAGISEHERANRVFDER LLTIEWERGELPEVPQIDAGSWLLLSASEADPLTAQLADALNAVGAQSTSVASASDVAQLRSLLGGRLTG VVVVTGPPTGGLTQCGRDYVSQLVGIARELAELPGEPPRLFVVTRSAASVLPSDLANLEQAGLRGLMRVI DSEHPHLGATAIDVDNDETVAALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRTAVVEYRRDG MRLQIRTPGDLESLEFVTFDRVAPGPGEIEVAVTASSVNFADVLVAFGRYPTFEGYRQQLGIDFAGVVTA VGPDVTEHRIGDHVGGMSANGCWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDD KVLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSRSTEFAEQIRGDTDGYGVDV VLNSLPGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLFPFRRNLSLYAVDLALLTHSHPHTVRRLLKT VYQHTVEGTLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVPPEQVRTSRPDGAYLVT GGLGGLGLFLAGELAAAGCGRIVLNSRSTPSPHATRVIERLRAAGADIQVECGDIADAATAHRVVAVATA SGLPVRGVLHAAAVVEDATLANVTDELIDRCWAPKVHGAWNIHRATAAQPLEWFCLFSSAAALVGSPGQG AYAAANSWLDAFAHWRRAQGLPATSIAWGAWAEIGRATALAEGTGAAIAPAEGARAFQTLLRYGRAYSGY APIMGTPWLTAFAQRSRFAEAFHATGQNQPATGKFLAELGSLPREEWPRTVRRLVSDQISLLLRRTIDPD RPLSDYGLDSLGNLELRTRIETETGIRVSPTKITTVRGLAEHVCDELAAAQSAPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1213 | pks3 | - | 100% (2085) | polyketide beta-ketoacyl synthase PKS3 |
| M. bovis AF2122 / 97 | Mb1554c | pks5 | 0.0 | 66.13% (2099) | polyketide synthase pks5 |
| M. bovis AF2122 / 97 | Mb3855c | pks2 | 0.0 | 65.11% (2101) | polyketide synthase PKS2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 32.43% (2183) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv1181 | pks4 | 0.0 | 99.94% (1582) | polyketide beta-ketoacyl synthase PKS4 |
| M. leprae Br4923 | MLBr_01229 | pks3 | 0.0 | 76.54% (2114) | mycocerosic acid synthase (polyketide synthase) |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 61.22% (2086) | polyketide synthase Pks5 |
| M. marinum M | MMAR_2340 | pks5 | 0.0 | 66.57% (2091) | polyketide synthase Pks5 |
| M. avium 104 | MAV_1321 | - | 0.0 | 76.05% (2088) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 64.01% (2106) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 66.30% (1810) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 63.20% (2098) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_0269 | - | 0.0 | 32.99% (2146) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
Mvan_0269|M.vanbaalenii_PYR-1 MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1 WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
Mvan_0269|M.vanbaalenii_PYR-1 RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mvan_0269|M.vanbaalenii_PYR-1 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1 GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
Mvan_0269|M.vanbaalenii_PYR-1 CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
Mvan_0269|M.vanbaalenii_PYR-1 DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1 GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP-LAAEPAQ
Mvan_0269|M.vanbaalenii_PYR-1 VEVVKETIPWER---DGGPRIAGVSSFGFAGTNAHVILEEAPEQAAAPGP
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAGTA
Mvan_0269|M.vanbaalenii_PYR-1 VQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAGAG
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWLFT
Mvan_0269|M.vanbaalenii_PYR-1 RAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWLFT
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVL
Mvan_0269|M.vanbaalenii_PYR-1 GQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAA
Mvan_0269|M.vanbaalenii_PYR-1 ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAA
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPA
Mvan_0269|M.vanbaalenii_PYR-1 CVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPS
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDP
Mvan_0269|M.vanbaalenii_PYR-1 LSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDP
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVE
Mvan_0269|M.vanbaalenii_PYR-1 ILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVE
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRRTT
Mvan_0269|M.vanbaalenii_PYR-1 FAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRRTA
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDS
Mvan_0269|M.vanbaalenii_PYR-1 ADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDN
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK REP--VAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRL
Mvan_0269|M.vanbaalenii_PYR-1 QDPDGSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLSRL
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDAT
Mvan_0269|M.vanbaalenii_PYR-1 AAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEAT
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAA
Mvan_0269|M.vanbaalenii_PYR-1 RPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHVGG
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LDAAES---DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGA
Mvan_0269|M.vanbaalenii_PYR-1 LDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTRRA
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLN
Mvan_0269|M.vanbaalenii_PYR-1 QHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLN
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVT
Mvan_0269|M.vanbaalenii_PYR-1 RITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDATYLVT
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVR
Mvan_0269|M.vanbaalenii_PYR-1 GGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQHSCQIR
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVD
Mvan_0269|M.vanbaalenii_PYR-1 VVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVD
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFGQAAYGAANAFL
Mvan_0269|M.vanbaalenii_PYR-1 RVFAGKVWGAWHLSEAAADLQLDFFLGTSSIASVWGGYGQTAYGAANAFL
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA
Mvan_0269|M.vanbaalenii_PYR-1 DGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRTLSPADALA
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAA
Mvan_0269|M.vanbaalenii_PYR-1 GLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAELEREVPDT
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAE
Mvan_0269|M.vanbaalenii_PYR-1 ----APAATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRVDATE
Mb1213|M.bovis_AF2122/97 --------------------------------------------------
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYL
Mvan_0269|M.vanbaalenii_PYR-1 IREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYL
Mb1213|M.bovis_AF2122/97 ----------------------MRTATATSVAVIGMACRLPGGIDSPQRL
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 ----------------------MRAANVTPVAVIGMACRLPGGIDSPQRL
MAV_1321|M.avium_104 --------------------------------------------------
MMAR_2340|M.marinum_M ---------------------------MTPVAVIGMACRLPGGIGSPEEL
MUL_2010|M.ulcerans_Agy99 -----------------------MQKSATPVAIIGMGCRLPGGVDSPEKL
MAB_3148c|M.abscessus_ATCC_199 -----------------------------------MGCRLPGGIESPEQF
MSMEG_4727|M.smegmatis_MC2_155 ----------------------MTQNCVAPVAIIGMACRLPGAINSPQQL
TH_4621|M.thermoresistible__bu -------------------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRL
Mflv_0405|M.gilvum_PYR-GCK LGDVLGLTEAATAPKAATVVSTAA---DEPIAIVAVSCRFPG-APNPEAF
Mvan_0269|M.vanbaalenii_PYR-1 LGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPG-APDPEAF
Mb1213|M.bovis_AF2122/97 WEALLRGDDLVGEIPADRWDANVYYDPEPGVPGRSVSRWGAFLDDVGGFD
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 WEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSVSRWGAFLDDVGGFD
MAV_1321|M.avium_104 ---MLRGDDLVGEIPADRWDADLYYDPEPGVPGRSVTRWGAFLDDVGGFD
MMAR_2340|M.marinum_M WEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVCKWGAFLDNVGDFD
MUL_2010|M.ulcerans_Agy99 WESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDVAGFD
MAB_3148c|M.abscessus_ATCC_199 WQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDVGGFD
MSMEG_4727|M.smegmatis_MC2_155 WEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDPAAFD
TH_4621|M.thermoresistible__bu WEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFD
Mflv_0405|M.gilvum_PYR-GCK WDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFD
Mvan_0269|M.vanbaalenii_PYR-1 WEVLAGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFD
Mb1213|M.bovis_AF2122/97 CDFFGLTEREATAIDPQHRLLLEVSWEAIEHAGVDPATLAESQTGVFVGL
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 CDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGVFVGL
MAV_1321|M.avium_104 CDFFGMTEREATAVDPQHRLLLETSWDAIEHAGLDPASLAGSQTGVFVGL
MMAR_2340|M.marinum_M PEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGVFVGL
MUL_2010|M.ulcerans_Agy99 AEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGVFVGL
MAB_3148c|M.abscessus_ATCC_199 ADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGV
MSMEG_4727|M.smegmatis_MC2_155 PEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGVFMGL
TH_4621|M.thermoresistible__bu PEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGL
Mflv_0405|M.gilvum_PYR-GCK PEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGV
Mvan_0269|M.vanbaalenii_PYR-1 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRGSRTGIFVGV
Mb1213|M.bovis_AF2122/97 THGDYELLS-ADCGAAEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTA
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 THGDYELLS-ADCGATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTA
MAV_1321|M.avium_104 THGDYELLS-ADCGAAEGPYGFAGTSNSFASGRVAYTLGLHGPAVTVDTA
MMAR_2340|M.marinum_M NHGDYQFVH-VDANTFDGPYGNTGTNSCFASGRISYAMRLHGPAVTVDTA
MUL_2010|M.ulcerans_Agy99 SHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTA
MAB_3148c|M.abscessus_ATCC_199 THNDYQLVA-ADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAG
MSMEG_4727|M.smegmatis_MC2_155 THNDYAHLA-ADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITVDTA
TH_4621|M.thermoresistible__bu SHDDYALLT-SDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTA
Mflv_0405|M.gilvum_PYR-GCK AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
Mvan_0269|M.vanbaalenii_PYR-1 AANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
Mb1213|M.bovis_AF2122/97 CSSGLTAVHQACRSLDDGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTG
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 CSSGLMAVHQARGSLDCGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTG
MAV_1321|M.avium_104 CSSGLMAVHQACGSLGGGESDLTLAGGVVVTLEPRKSVSGSLQGMLSPTG
MMAR_2340|M.marinum_M CSSSLYATHLACNSLSEGESDLAFAAGVYVMLEPRRFASGSAQNMLSPTG
MUL_2010|M.ulcerans_Agy99 CSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTG
MAB_3148c|M.abscessus_ATCC_199 CAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTG
MSMEG_4727|M.smegmatis_MC2_155 CSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLSPTG
TH_4621|M.thermoresistible__bu CSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTG
Mflv_0405|M.gilvum_PYR-GCK CSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVG
Mvan_0269|M.vanbaalenii_PYR-1 CSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLSPVG
Mb1213|M.bovis_AF2122/97 RCHAFDEAADGFVSGEGCVVLLLKRLPDAVRDGDRVLAIVRGTAANQDGR
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 RCHAFDVAADGFVSGEGCVVLLLKRMPDAERDGDRILAVLRGTAANQDGH
MAV_1321|M.avium_104 RCHAFDVNADGFVSGEGCVMLLLKRLDDARRDGDRILAVLRGTAANQDGR
MMAR_2340|M.marinum_M HCHAFDVDADGFVSGEGSVVLLLKRLADAQRDGDRILAVMRGTAANQDGH
MUL_2010|M.ulcerans_Agy99 RCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGR
MAB_3148c|M.abscessus_ATCC_199 RCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGR
MSMEG_4727|M.smegmatis_MC2_155 HCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATNQDGR
TH_4621|M.thermoresistible__bu RCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGR
Mflv_0405|M.gilvum_PYR-GCK RCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGA
Mvan_0269|M.vanbaalenii_PYR-1 RCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGA
Mb1213|M.bovis_AF2122/97 TVNIAAPSAQAQIAVYQQALAAAGVEASTVGMVEAHGTGTPVGDPVEYAS
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 TVHIAAPSEQAQIAVYHKALAVGGVDPTTVGLIEAHGTGTPVGDPIEYAS
MAV_1321|M.avium_104 TVNISAPSETAQVAVYRKALQAADIDATTVGLVEAHGTGTPVGDPIEYSS
MMAR_2340|M.marinum_M TVNIATPSVEAQSAVYRAALATAGVDGASVGLVEAHGTGTPVGDPIEFES
MUL_2010|M.ulcerans_Agy99 SETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPIEYRS
MAB_3148c|M.abscessus_ATCC_199 TVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTG
MSMEG_4727|M.smegmatis_MC2_155 TVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPLEFSS
TH_4621|M.thermoresistible__bu TENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNS
Mflv_0405|M.gilvum_PYR-GCK SSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQA
Mvan_0269|M.vanbaalenii_PYR-1 SSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQA
Mb1213|M.bovis_AF2122/97 LAAVYGTEGP----CALTSVKTNFGHLQSASGPLGLMKTILALRHGVVPQ
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 LAAVYGTAGR----CALASTKTNFGHMQSTSGPLGMMKAILALQHGVVPK
MAV_1321|M.avium_104 LAAVYGTDGP----CVLGSVKTNFGHLQSASGPLGMMKAILALQHGVVPR
MMAR_2340|M.marinum_M LARVYGIDRP----CALTSAKPNFGHMQAGAGVLGLMKAILALQHGVIPP
MUL_2010|M.ulcerans_Agy99 LAQVYGSGGSR---CMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MAB_3148c|M.abscessus_ATCC_199 LAQVYGVDGP----CAVGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPP
MSMEG_4727|M.smegmatis_MC2_155 LAEVYGTDGP----CALGSIKTNFGHTQSAAGALGVMKAVLALQHNVIPQ
TH_4621|M.thermoresistible__bu LTQVYGKTGP----CALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQ
Mflv_0405|M.gilvum_PYR-GCK AAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQ
Mvan_0269|M.vanbaalenii_PYR-1 AAAAYGASRDADRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHNLLPQ
Mb1213|M.bovis_AF2122/97 NLHFCRLPDQLAEIDTELFVPQANTSWPDNTGQPRRAAVSSYGMSGTNVH
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 NLHFTRLPDQLAEITTELFVPQVNTPWPVDVQQPRRAAVSSYGMSGTNVH
MAV_1321|M.avium_104 NLHFTRLPDEMARINTELFVPQENTPWTSNGHHPRRAAVSSYGMSGTNVH
MMAR_2340|M.marinum_M NIHFSRLPDEMAQIKSGLFVPQEITQWPTNGEQTRTAAVSSYGISGTNVH
MUL_2010|M.ulcerans_Agy99 MVHHTRLPDELAEIETGLYVPHEITPWPED-QGPRRIAVSSFGMSGTNVH
MAB_3148c|M.abscessus_ATCC_199 NLHFTGIPDKLAPVKTNLFVPQTVIPWPGKAQGPRRAGVSAYGMSGSNVH
MSMEG_4727|M.smegmatis_MC2_155 NLHFTRLPDQMAEIETGLFVPETITPWPVREGQPRRAAVSAYGLSGTNVH
TH_4621|M.thermoresistible__bu NLHFTRLPDEMAAIETNLFVPQATTLWPVREGCPRRAAVSSYGMSGTNVH
Mflv_0405|M.gilvum_PYR-GCK SLHFDTPSPHIPWDSLPVRVVDTAMPWQPN-GRPRRAGVSSFGFTGTNAH
Mvan_0269|M.vanbaalenii_PYR-1 SLHFENPSPHIPWDSLPVRVVDKAIPWQAD-GRPRRAGVSSFGFTGTNAH
Mb1213|M.bovis_AF2122/97 AILEQAPVSEPA-----------ASGPELTPEAGGLALFPVSATSAEQLH
Rv1181|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01229|M.leprae_Br4923 AILEQAPENS-------------GKDSPAVSKVNGPLLFPLSATSVEQLR
MAV_1321|M.avium_104 AILEEAPAPA--------------AASSAAPETVGPLLFPLSSTSAEQLR
MMAR_2340|M.marinum_M AILEQAPETA-T-----------HDAEPVSPAIEGALIFPLSATSADGLR
MUL_2010|M.ulcerans_Agy99 AILEEPPTPAPA-----------RDQASAEPGMASPLLFALSSTSADGLR
MAB_3148c|M.abscessus_ATCC_199 AVVEQAPPVES------------STPPAVESPLGSQLIFPVSSTSAEELR
MSMEG_4727|M.smegmatis_MC2_155 AVLEQAPESPAE-----------TAAEAISPKAGNALVFPVSASSADALR
TH_4621|M.thermoresistible__bu AVLEQAPEPVQ------------RPEESADTDAAGPLVFALSSTSAEELR
Mflv_0405|M.gilvum_PYR-GCK VLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEALV
Mvan_0269|M.vanbaalenii_PYR-1 VLIEEAPLPQA--------ADPVEE---PDTRALPVGVLALSARSPEALT
Mb1213|M.bovis_AF2122/97 VTAARLADWVDQNG----NAGSRVSMRDLGYTLSCRRAHRPVRTVVTASS
Rv1181|M.tuberculosis_H37Rv ---------------------------------------------MTASS
MLBr_01229|M.leprae_Br4923 ATAARMADWVDEHG----SGTKHTGLWDLGYTLSRRRGYRPVRTMVLASS
MAV_1321|M.avium_104 VTAARLAAWLDEQAGDALAGLRGWGLRDLGYTLTRRRAHRPVRTVVSASG
MMAR_2340|M.marinum_M QTAKRLADWVDAQGP-------ELATSDLAYTLARRRGHRPVRTAVLADN
MUL_2010|M.ulcerans_Agy99 QTARELAEWVGSRADS----ADSTEAVDLAYTLARRRAHRPVRTAVVAAS
MAB_3148c|M.abscessus_ATCC_199 RTAARLADWVAERP--------EVAPGDVGYTLARRRAHRSVRTAVVADG
MSMEG_4727|M.smegmatis_MC2_155 STAQHLADWLLRSGDGN-GRGPAIDLGDLAYTLARRRGFRAARSAVLAGD
TH_4621|M.thermoresistible__bu RTAGRLAEWVEAHTD-------EVVPADLAYTLARRRAHRPVRTTVIADG
Mflv_0405|M.gilvum_PYR-GCK ALAQRYETWLTAHP--------EADLADVCRTAGTGRSHFEHRAALVVDS
Mvan_0269|M.vanbaalenii_PYR-1 ALAQRYEAWLSAHP--------DADLADVCRTAGTGRSHFEHRAALVVDS
: . .
Mb1213|M.bovis_AF2122/97 FDELSAALRDVAGDQIPYQPAVGHDDRGP--VWVFSGQGSQWPGMGTELL
Rv1181|M.tuberculosis_H37Rv FDELSAALRDVAGDQIPYQPAVGHDDRGP--VWVFSGQGSQWPGMGTELL
MLBr_01229|M.leprae_Br4923 FAELSRGLREIAGSEIPYQSAVGQDDRGP--VWVFSGQGSQWAGMGAELF
MAV_1321|M.avium_104 FAELRTELRAVADGDIPYQPAVGQGDRGP--VWVFSGQGSQWSQMGAELL
MMAR_2340|M.marinum_M VSELSAGLHEIADDETPYQAAVGRDDRGP--VWVFSGQGSQWKAMGADLL
MUL_2010|M.ulcerans_Agy99 LPELVEGLQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAMGADLL
MAB_3148c|M.abscessus_ATCC_199 ADELIDALRGVAEGDAPYPAAVAQDDRGP--VWLFSGQGSQWAGMGAELL
MSMEG_4727|M.smegmatis_MC2_155 RGTLVEGLRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASMGAELL
TH_4621|M.thermoresistible__bu VEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMGAELL
Mflv_0405|M.gilvum_PYR-GCK VESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARELF
Mvan_0269|M.vanbaalenii_PYR-1 VAAAREGLAELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMARELF
* :* . . . * .*:*:*****: *. :*:
Mb1213|M.bovis_AF2122/97 VAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSG---------IDRV
Rv1181|M.tuberculosis_H37Rv VAEPVFAATVAAMEPVIARESGFSVTEAMSAPQTVSG---------IDRV
MLBr_01229|M.leprae_Br4923 AKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTG---------IDRV
MAV_1321|M.avium_104 DKEPVFAATIAAVEPLIAAESGFSVTRALSAPPAVTG---------IDKV
MMAR_2340|M.marinum_M ANEPVFAATVAELEPLIAAESGFSVTEAMTAIETVTG---------IDRV
MUL_2010|M.ulcerans_Agy99 ANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTG---------IDKV
MAB_3148c|M.abscessus_ATCC_199 GKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTG---------IDRV
MSMEG_4727|M.smegmatis_MC2_155 DREPAFAAAIAELEPLIAAESDFSVTEALTASETVTG---------IDRV
TH_4621|M.thermoresistible__bu ATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG---------IDRV
Mflv_0405|M.gilvum_PYR-GCK DTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFA
Mvan_0269|M.vanbaalenii_PYR-1 ETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG----EALRHTSFA
* .** :: : .: .: . :* . .
Mb1213|M.bovis_AF2122/97 QPTIFAVQVALAAALKS-YGVRPGAIIGHSLGEAAAAVVAGALSLHDGLR
Rv1181|M.tuberculosis_H37Rv QPTIFAVQVALAAALKS-YGVRPGAIIGHSLGEAAAAVVAGALSLHDGLR
MLBr_01229|M.leprae_Br4923 QPTIFAIQVALAATMKS-YGVYPGAVIGHSLGEAAAAVAAGALSCEDGLR
MAV_1321|M.avium_104 QPTIFAMQVALAETMKS-YGVRPGAVIGHSLGECAAAVVAGGLSLGDGVK
MMAR_2340|M.marinum_M QPTIFTMQVALAATMKS-YGVRPGAIIGHSLGESAAAVAAGALSLEDGAK
MUL_2010|M.ulcerans_Agy99 QPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGAR
MAB_3148c|M.abscessus_ATCC_199 QPTLFAMQVSLAATLAS-YGVRPGAVIGHSMGEVAAAVVSEALSLEDGVK
MSMEG_4727|M.smegmatis_MC2_155 QPTIFAVQVALAAAMRS-HGVVPGAVIGHSMGEVAASVVSGALSLEDGVK
TH_4621|M.thermoresistible__bu QPTLFAIQVALAATMQS-YGVRPGAVIGHSLGEVAAAVVAGALSLEDGVK
Mflv_0405|M.gilvum_PYR-GCK QPALFAVEMGLARLWQS-WGIVPDVVLGHSVGQYAAACVAGVFSLEDGAR
Mvan_0269|M.vanbaalenii_PYR-1 QPAIFAVEMGLARLWQS-WGIEPDVVLGHSVGQYAAACVAGVFSLEDGAR
**::*::::.** . *: *..::***:*: **: .: :* ** :
Mb1213|M.bovis_AF2122/97 VICRRSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTS
Rv1181|M.tuberculosis_H37Rv VICRRSRLMSRIAGSGAMASVELPGQQVLSELAIRGISDVVLSVVASPTS
MLBr_01229|M.leprae_Br4923 VICRRSQLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTS
MAV_1321|M.avium_104 VICRRSRLMARIAGRGAMASVELPGQQVLSELSIRGISDVVLSVVASPTS
MMAR_2340|M.marinum_M VICRRSRLMTRISGSGAMASVELPAQQVLSELMARGINDVVVAVVASPQS
MUL_2010|M.ulcerans_Agy99 VISRRSKLMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQS
MAB_3148c|M.abscessus_ATCC_199 VICRRSQLMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQS
MSMEG_4727|M.smegmatis_MC2_155 VICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQS
TH_4621|M.thermoresistible__bu VICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPES
Mflv_0405|M.gilvum_PYR-GCK LMAERGRLFGSLPEGGRMVAVFADAK--RVEQVAADFPRVSVGAYNGP-N
Mvan_0269|M.vanbaalenii_PYR-1 LMAERGRMFGSLPEGGRMVAVFTDAK--LVEEIAGDFPRVSVGAYNGP-N
::..* :: :. * *. : .: .. * :.. .* .
Mb1213|M.bovis_AF2122/97 TVVGGATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLA
Rv1181|M.tuberculosis_H37Rv TVVGGATQSIRDLVAAWEQQDVLAREVAVDVASHTPQVDPILDELLEVLA
MLBr_01229|M.leprae_Br4923 TVVGGDTQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLA
MAV_1321|M.avium_104 TVVGGDAEAIRELVAAWQQQDVMAREVAVDVASHSPQVESILDELVEVLA
MMAR_2340|M.marinum_M TVIGGATDTVRELVAAWEQREVMAREVAVDVASHSPQVDPILDDLYDVLA
MUL_2010|M.ulcerans_Agy99 TVVGGATDTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLATALA
MAB_3148c|M.abscessus_ATCC_199 TVVGGATETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALE
MSMEG_4727|M.smegmatis_MC2_155 TVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALA
TH_4621|M.thermoresistible__bu TVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILA
Mflv_0405|M.gilvum_PYR-GCK TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAA
Mvan_0269|M.vanbaalenii_PYR-1 TVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYAA
**:.* :..:: : : : .. * *: ::.:*:::
Mb1213|M.bovis_AF2122/97 EVDPTAPEIPYYS-ATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALK
Rv1181|M.tuberculosis_H37Rv EVDPTAPEIPYYS-ATLWDPRERPSFTGEYWVENLRYTVRFAAAVQAALK
MLBr_01229|M.leprae_Br4923 DLKPTEPKVPYYS-ATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAALK
MAV_1321|M.avium_104 ELEPTAPEVPYYS-ATLWNPRERPSFGGDYWAENLRHTVRFAAAVQAALK
MMAR_2340|M.marinum_M DLEPLTPEVPYYS-ATLFDPREEPYCDGSYWVDNLRHTVRFGAAVQAALE
MUL_2010|M.ulcerans_Agy99 DIVPSDPKVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAALE
MAB_3148c|M.abscessus_ATCC_199 DLTPRTPVVPLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALD
MSMEG_4727|M.smegmatis_MC2_155 DLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAALE
TH_4621|M.thermoresistible__bu DLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALE
Mflv_0405|M.gilvum_PYR-GCK QLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAA
Mvan_0269|M.vanbaalenii_PYR-1 QFQFATPTLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAESVRTVAA
:. * :* . . . . ** : * *:*. :*::.
Mb1213|M.bovis_AF2122/97 DGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFV
Rv1181|M.tuberculosis_H37Rv DGYRVFGELAPHPLLTYAVEQNAASLDMPIATLAAMRRGEQLPFGLRGFV
MLBr_01229|M.leprae_Br4923 DGFRVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGFI
MAV_1321|M.avium_104 DGFRVFGELAPHPLLTHAVEQNAASLDVPIAALAAMRREQELPLGLRGFV
MMAR_2340|M.marinum_M DGYRVFAELAPHPLLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLRGLL
MUL_2010|M.ulcerans_Agy99 DGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHGLRGLL
MAB_3148c|M.abscessus_ATCC_199 DGYRVFGELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDFV
MSMEG_4727|M.smegmatis_MC2_155 DGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGFV
TH_4621|M.thermoresistible__bu DGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMV
Mflv_0405|M.gilvum_PYR-GCK LGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIADAL
Mvan_0269|M.vanbaalenii_PYR-1 LGCSVLMEIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDRRQITEAL
* *: *:.*:*:*. . : . .: .:*: : :
Mb1213|M.bovis_AF2122/97 ADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSRE-DSHRSHTGAV
Rv1181|M.tuberculosis_H37Rv ADVHNAGAKVDFSVQYPDGRLVDAPLPSWTHRTLMLSRE-DSHRSHTGAV
MLBr_01229|M.leprae_Br4923 ADVHSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAV
MAV_1321|M.avium_104 GDLHSSGALVDFSVQYPAGRLVDAPLPTWAHRRLMLRRE-SVQRAHGSSV
MMAR_2340|M.marinum_M ADLHSAGAAVDFSVLYPAGELVDAPLPAWTHQSLLLNRAGQDHQAQGGSS
MUL_2010|M.ulcerans_Agy99 TDVHSAGAAVDFSVLYPAGRLVNAPPPAWTHRRFFVDGEGQDSKAQGACS
MAB_3148c|M.abscessus_ATCC_199 GDLYTAGGAVDFSVLYPTGQLVDVPLPSWTRRSYLLDLSAQAQQGHGTHT
MSMEG_4727|M.smegmatis_MC2_155 ADLHSAGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDRELESSAP-GVPS
TH_4621|M.thermoresistible__bu GDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCT
Mflv_0405|M.gilvum_PYR-GCK AAAYIGGHKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMAIDGRVGA
Mvan_0269|M.vanbaalenii_PYR-1 AAAYVGGHRPDFGALYRRPGRAVALPTYPFQRRRFWPKTSGITTDG----
. .* **.. : . : .
Mb1213|M.bovis_AF2122/97 QAVHPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAY
Rv1181|M.tuberculosis_H37Rv QAVHPLLGAHVHLLEEPERHVWQAGVGTGAHPWLGDHRIHNVAAFPGAAY
MLBr_01229|M.leprae_Br4923 QAVHPLLGAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAY
MAV_1321|M.avium_104 QAVHPLLGAHVHLREEPERHVWQGEVGTDAHPWLADHQIHGVAAFPGAGY
MMAR_2340|M.marinum_M VVVHPLLGSHVLLPEEPERHVWQSDVGTEALPWLADHQIHSAPALPGAAY
MUL_2010|M.ulcerans_Agy99 VTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAY
MAB_3148c|M.abscessus_ATCC_199 VAVHPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAY
MSMEG_4727|M.smegmatis_MC2_155 VSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAY
TH_4621|M.thermoresistible__bu ITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAY
Mflv_0405|M.gilvum_PYR-GCK SAGSGILGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTVVVPGATY
Mvan_0269|M.vanbaalenii_PYR-1 PAVSGILGSAKDLASG--DTVYTSRWSVRSQPWLADHVIYGTVVVPGATY
:**: * . :: .. .*:.** : . . *** *
Mb1213|M.bovis_AF2122/97 CEMALAAARTTLG-ELSEVRDIKFEQTLLLDEQTVVSSAATIAAP--GIL
Rv1181|M.tuberculosis_H37Rv CEMALAAARTTLG-ELSEVRDIKFEQTLLLDEQTVVSSAATIAAP--GIL
MLBr_01229|M.leprae_Br4923 CEMALTAARVTLG-EASEVRDIKFEQTLLLDRETMASSAATVSAP--GVL
MAV_1321|M.avium_104 CEMALAAAAATLG-ERAEVRDVTFEQTLLLAGRTEVSSTATVTGP--GRL
MMAR_2340|M.marinum_M CEMALVAARTILG-DAAEVRDVRFEQMLLLDDETPLSAVGSVKSP--GIV
MUL_2010|M.ulcerans_Agy99 CEMALAAAGEVFG-EAFEVRDLAFEQMLLLDEETPIDAVASLDSP--GAA
MAB_3148c|M.abscessus_ATCC_199 CEMALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAKSA--DIL
MSMEG_4727|M.smegmatis_MC2_155 CEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVTAP--GTA
TH_4621|M.thermoresistible__bu CEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEP--GTL
Mflv_0405|M.gilvum_PYR-GCK AAMALAAVGTPAH-----AKDVFFYEPIILPEKSSREVQLTVHPSVDGES
Mvan_0269|M.vanbaalenii_PYR-1 AAMALAAVGTPAR-----VKDVFFYEPIILPEKASREVQLTLHPSEDGGQ
. *** *. .:.: * : : * : : . .
Mb1213|M.bovis_AF2122/97 QFAVESHQEGEPARRASAMLHALEEMP----QPPGYDTNALTAAHESSMS
Rv1181|M.tuberculosis_H37Rv QFAVESHQEGEPARRASAMLHALEEMP----QPPGYDTNALTAAHESSMS
MLBr_01229|M.leprae_Br4923 EFAVETYEEGERVRRASAVLRALEDRVN--QQPASHSIDALIASHPLRTE
MAV_1321|M.avium_104 EFTVDTHEDGERIRRAGAVLHALPPEHGGETGPPAHDVATLIADHPSRIE
MMAR_2340|M.marinum_M DFVVETFQDGGAVRRGGAVLHAVEDDD----QLPAYDIPALLAEHSRTED
MUL_2010|M.ulcerans_Agy99 NFVVQTHVDGETTRHATAALRASDDES----VPPAYDIAALLAAHPVSVN
MAB_3148c|M.abscessus_ATCC_199 EFVVETHDEGDVVKRATAVLGNGGDVD----MPIAYDLSALRAEHPHRES
MSMEG_4727|M.smegmatis_MC2_155 EFGVETHQSGDRTQRATAVLRGDVDAER----PAAHSIDALLAAHPNRVD
TH_4621|M.thermoresistible__bu EFAVETAKDGEHERRATAVLGAADDTEP----PQAHDIDALLAEHPTRIE
Mflv_0405|M.gilvum_PYR-GCK KFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERLN
Mvan_0269|M.vanbaalenii_PYR-1 KFQVHSREYGERGTEWSLNAEGTVASGVDENPQAE--PSGPVDEAIERLN
.* *.: * . .
Mb1213|M.bovis_AF2122/97 ---GEELRKMFNSLGIQYGPAFSGLVAVHTARG---AVTTVLAEVALPGA
Rv1181|M.tuberculosis_H37Rv ---GEELRKMFNSLGIQYGPAFSGLVAVHTARG---DVTTVLAEVALPGA
MLBr_01229|M.leprae_Br4923 ---GADLRATFDAIGIQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGA
MAV_1321|M.avium_104 ---GAELRKAFGAVGIQYGPAFSGLAAVSVGDR---DVGTVLAEVALPGA
MMAR_2340|M.marinum_M ---GEELRARFDEHGVQYGPAFTGLGNAHIADG---AVSSVVAEVALPGA
MUL_2010|M.ulcerans_Agy99 ---GAELREAFVERGIQHGPAFSGLAIARTAET---EGGTVLAEVALPAS
MAB_3148c|M.abscessus_ATCC_199 ---GDDLRASFDERGVQYGPAFQGLAAAYRGDE---TVRSVLAEVTLPRD
MSMEG_4727|M.smegmatis_MC2_155 ---GDELRAGFGTVGIGHGAAFAGLSEAYVATA---AEPTVVAAVALPGP
TH_4621|M.thermoresistible__bu ---GDELRQWFDQRGVQFGPAFTGLTAARIPEG---TVTSVLAEVGLPGQ
Mflv_0405|M.gilvum_PYR-GCK RMRPQELFETFADLELAWGPTWSGSLKSLWLGE-----GEAIGDILVGAE
Mvan_0269|M.vanbaalenii_PYR-1 RMRPQDLFETFADMELAWGPTWSGSLKSLWLGE-----GEAIGDILVGEE
:* * : * :: * .:. : :
Mb1213|M.bovis_AF2122/97 IRSQQSAYASHPALLDACF---QSVLVHPEVQKATVGGLMLPVGVRRLRN
Rv1181|M.tuberculosis_H37Rv IRSQQSAYASHPALLDACF---QSVLVHPEVQKATVGGLMLPVGVRRLRN
MLBr_01229|M.leprae_Br4923 IRSQQASYTSHPALLDACF---QSVIVAPEVQKAGAGGLLLPVYVRRLLN
MAV_1321|M.avium_104 IRSQQSGYGAHPALLDACL---QSVIAAPEVQRAGAGGLLLPVGVRRLRN
MMAR_2340|M.marinum_M MRSQQRAYAIHPALLDACF---QAVGAHPDVQVAGNGGLMLPLGVRQIRA
MUL_2010|M.ulcerans_Agy99 IRFQQGAYGVHPALLDACF---QSVAAG--VKSTGGGGLLLPLGVRSLRA
MAB_3148c|M.abscessus_ATCC_199 VRAQQGSYIVHPALLDACF---QSVIALPDVQEASKDALPLPKGVRSLHA
MSMEG_4727|M.smegmatis_MC2_155 LRSGQRGYTVHPALLDACF---QSVIAHPEVQNIASG-MLLPLGVRRLRA
TH_4621|M.thermoresistible__bu IRSQQAPYGIHPALLDACF---QSVAAHPDVQGAGSG-LLLPLGVRRLQA
Mflv_0405|M.gilvum_PYR-GCK LAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSL
Mvan_0269|M.vanbaalenii_PYR-1 LAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYGQVTL
: **.*:* * .. . . : ** :
Mb1213|M.bovis_AF2122/97 YHSTRSAHYCLARVTSSS-RAGECEADLDVFDQAGTVLLTVEGLRLAAGI
Rv1181|M.tuberculosis_H37Rv YHSTRSAHYCLARVTSSS-RAGECEADLDVFDQAGTVLLTVEGLRLAAGI
MLBr_01229|M.leprae_Br4923 YHSMRNAQYCLTRVKTS--RAGECEVDLEVLDQSGAVLLLVEGLRLAGGA
MAV_1321|M.avium_104 YHSTRNAHYCLTRITSS--RPGECEADVDVLDQSGTVLLTVEGLRLAGAA
MMAR_2340|M.marinum_M YASTRNAHYCYARVTSV--DTSAVEADLDVLDEHGTVLVAVRGLQLGTGV
MUL_2010|M.ulcerans_Agy99 YGPTRNAQYCYTRVTKA--DANGGEADLELLDEQGCVLLAVRGLRLGTGT
MAB_3148c|M.abscessus_ATCC_199 YESARATQYCYTRVTKV--VGNEVEADIDLLDETGSVLIAVRGFRFGTGS
MSMEG_4727|M.smegmatis_MC2_155 YGSTRNVRYCLSRIVKA--DSFGVEADLELLDADGTVLLSAMGLQLGTGN
TH_4621|M.thermoresistible__bu FGPTRGARYCYARVTDA--DGSKAEADLDVLDEHGNVLLRVQGLLMGGAA
Mflv_0405|M.gilvum_PYR-GCK QEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAP
Mvan_0269|M.vanbaalenii_PYR-1 RDKMPRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGIREFTVKRAP
** : *:: :* * * : . .
Mb1213|M.bovis_AF2122/97 SEHERA--NRVFDERLLTIEWERGELPEVP---QIDAGSWLLLSASEADP
Rv1181|M.tuberculosis_H37Rv SEHERA--NRVFDERLLTIEWERGELPEVP---QIDAGSWLLLSASEADP
MLBr_01229|M.leprae_Br4923 SEHECA--NRVLDERLFTVEWEPRELPEVT---QRERGSWLVLGASAEDP
MAV_1321|M.avium_104 SEHEHA--QRLLDDRLLTIEWEARELPEAP---QGEPGSWLLLSACDAAS
MMAR_2340|M.marinum_M SEEGNR--DRVLNERLLTIEWQQRELPEVD---AAEAGAWLLISTSDGAD
MUL_2010|M.ulcerans_Agy99 SESGER--DRVLSERLLTLEWQQRQLPEVL---DEETGSWLLISASDGED
MAB_3148c|M.abscessus_ATCC_199 SDDEQR--DQLLNNRLLAIEWQQQRLPESV---SGAPRRWLLVSTGESVD
MSMEG_4727|M.smegmatis_MC2_155 SDKAEE--ERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAGDDDE
TH_4621|M.thermoresistible__bu ADGDDR--DRVLGERLLTIEWQRRDLPEAD----SAAGKWLLVSTSATAD
Mflv_0405|M.gilvum_PYR-GCK REALLRGLGGDATRLLYTLGWHEVPVPESGDG-AAPQGTWLIGGFDELAV
Mvan_0269|M.vanbaalenii_PYR-1 REALLRGLGGDATRLLYTLGWHEVPAPASGD--AALNGNWLIAGFDELAA
: * :: *. * **:
Mb1213|M.bovis_AF2122/97 -----LTAQLADALNAVGAQSTSVASAS---DVAQLRSLLGG--------
Rv1181|M.tuberculosis_H37Rv -----LTAQLADALNAVGAQSTSVASAS---DVAQLRSLLGG--------
MLBr_01229|M.leprae_Br4923 -----LVQQLGDALNADGGHCTAVSLPLGQIDTAQLCSLLSRDGVSSSIG
MAV_1321|M.avium_104 NGDDALTTQLADVLKTDGAQCRTVSLPPGAVDTEELRSLLSG-GEPGGNG
MMAR_2340|M.marinum_M ----MLAAELTDALKLHSAQCATTSWHENAADHAASAERLRN--------
MUL_2010|M.ulcerans_Agy99 ----LMATTLADALKSQGAECASMVWSA-QDDLAGGIEKLGA--------
MAB_3148c|M.abscessus_ATCC_199 P----WAAELIDSLKVRESEVSLIQWRPNTDRVAALKLLYDQ--------
MSMEG_4727|M.smegmatis_MC2_155 N---PRAAGVVSALIGAGMPTTTMAWSHDADHDAQAAALTAR--------
TH_4621|M.thermoresistible__bu VS----ATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAG--------
Mflv_0405|M.gilvum_PYR-GCK S---------VPGCIPADR-TNPESLRQLLTDAHGRGLPFSG--------
Mvan_0269|M.vanbaalenii_PYR-1 G---------VPGCIPFDRSTDPEPLGQLLAQAHERGIGFSG--------
Mb1213|M.bovis_AF2122/97 -----RLTGVVVVTGPPT----GGLT----QCGRDYVSQLVGIARELAEL
Rv1181|M.tuberculosis_H37Rv -----RLTGVVVVTGPPT----GGLT----QCGRDYVSQLVGIARELAEL
MLBr_01229|M.leprae_Br4923 HGALKGLTGVVVVTAPPATVAESPAL----RRGRDYVSHLITIVREISEL
MAV_1321|M.avium_104 HRPLQRLTGVVVVAAASEAD-HPAAP----RRGRDYVSHLATVARELSEL
MMAR_2340|M.marinum_M QLNAGGFHNAVILLKPDSGDRDENSG----VEGVECVRHVVRVVRELPEI
MUL_2010|M.ulcerans_Agy99 QLRARTNKGVVIVCGPRSGDADEQSL----LQGREQVRHLVRITRGLAEL
MAB_3148c|M.abscessus_ATCC_199 -LESGTFDGVLVVTAPGSEGGADRVV----LQGADQVRHLVRITRELVDL
MSMEG_4727|M.smegmatis_MC2_155 -LDEQPLAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADA
TH_4621|M.thermoresistible__bu --IADGVTGVVVLTGPKNGNPDDAAA----RRGSDYVRHLVRITRELAEI
Mflv_0405|M.gilvum_PYR-GCK -----------VVWRAARSDGDESDAEVAARLEAEIAELLGAVHTVQGGE
Mvan_0269|M.vanbaalenii_PYR-1 -----------VVWRAAAPSADESSTAMAARIETEIADLLSAVHTVQNGA
:: : . : :
Mb1213|M.bovis_AF2122/97 PGEPPRLFVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAID
Rv1181|M.tuberculosis_H37Rv PGEPPRLFVVTRSAASVLPSDLANLEQAGLRGLMRVIDSEHPHLGATAID
MLBr_01229|M.leprae_Br4923 PGERPRLFVVTRNAASIKTGDLANLEQVGLRGLIRVIDSEHPYLSVTQID
MAV_1321|M.avium_104 PGESPRLFVLTRNAAVVVAGDAPNLTQAGLRGMMRVIDAEHPHLSATQID
MMAR_2340|M.marinum_M MGEAPRLFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVD
MUL_2010|M.ulcerans_Agy99 EGELPRLFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVD
MAB_3148c|M.abscessus_ATCC_199 PGEPPRLFVVTRNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHID
MSMEG_4727|M.smegmatis_MC2_155 VGEPPRLYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQID
TH_4621|M.thermoresistible__bu DGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQID
Mflv_0405|M.gilvum_PYR-GCK VKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVD
Mvan_0269|M.vanbaalenii_PYR-1 VKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLVD
*:::*. : : : .* *: *. * * * :*
Mb1213|M.bovis_AF2122/97 VDND--ETVAALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRT
Rv1181|M.tuberculosis_H37Rv VDND--ETVAALVASQLQSGSQEDETAWRNGIWYTARLRPGPLRPAERRT
MLBr_01229|M.leprae_Br4923 VEETNQATIATQVARQLRSGSDEDETGWRDGEWYTARLRPGPLRQAERRT
MAV_1321|M.avium_104 VDDA---TDPGHVARQLQSRSGEDETAWRDGQWYTARLRPGPLRPADRRT
MMAR_2340|M.marinum_M VDEH---SGSEVVARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKT
MUL_2010|M.ulcerans_Agy99 VDES---TQAEQLAQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQT
MAB_3148c|M.abscessus_ATCC_199 VDRH---TAAQNVAGELVSGSEEDETAWREDHWYRARLNLGPLGPDDWRS
MSMEG_4727|M.smegmatis_MC2_155 VDDS---TAHEALVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRT
TH_4621|M.thermoresistible__bu IADD---ADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQ
Mflv_0405|M.gilvum_PYR-GCK CDGS--PQAVQALAALLSTPVDEPELAVRQGKLLASRLLP-----WSRSG
Mvan_0269|M.vanbaalenii_PYR-1 VDGS--PEAVLALAGLLAAPVDEPELAVRQGKLLASRLLP-----WARSG
:. * * * . * . :**
Mb1213|M.bovis_AF2122/97 AVVEYRRDGMRLQIRTPGDLESLEFVTFDRVAPGPGEIEVAVTASSVNFA
Rv1181|M.tuberculosis_H37Rv AVVEYRRDGMRLQIRTPGDLESLEFVTFDRVAPGPGEIEVAVTASSVNFA
MLBr_01229|M.leprae_Br4923 VVVQNEHDGMRLEIRTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFA
MAV_1321|M.avium_104 TVVDHGRDGMRLHIRTPGDLESLELTAFDRVPPGPGEIEVAVASSTINFA
MMAR_2340|M.marinum_M TVVEHDTEGMRLQIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFA
MUL_2010|M.ulcerans_Agy99 TVVDHERDNMRLQIRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFA
MAB_3148c|M.abscessus_ATCC_199 TVATPNNEGVRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFA
MSMEG_4727|M.smegmatis_MC2_155 AVADNASEGMRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFA
TH_4621|M.thermoresistible__bu AVVDCERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFA
Mflv_0405|M.gilvum_PYR-GCK HLTVPRGGDYVLAPTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFR
Mvan_0269|M.vanbaalenii_PYR-1 HLTVPRSADYVLAPTERGAIDNLRLTETDVAPPAEGYVQVRVEAAGLNFR
:. . : * ::.: :. : .*. * ::* * : :**
Mb1213|M.bovis_AF2122/97 DVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRIGDHVGGMSANG
Rv1181|M.tuberculosis_H37Rv DVLVAFGRYPTFEGYRQQLGIDFAGVVTAVGPDVTEHRIGDHVGGMSANG
MLBr_01229|M.leprae_Br4923 DVLVAFGRYPTFEGYCQLLGIDFAGVVSAVGLNVTDHKVGDRVGGVSRNG
MAV_1321|M.avium_104 DVLVAFGRYPTFEGYQQQLGGDFAGVVTAVGPGVTEHRVGDRVGGLSGNG
MMAR_2340|M.marinum_M DVLVSFGRYNSPDGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHG
MUL_2010|M.ulcerans_Agy99 DVLIAFGRYPSLEGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDG
MAB_3148c|M.abscessus_ATCC_199 DVLNVYGRYSSFEG-RQELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTG
MSMEG_4727|M.smegmatis_MC2_155 DVLVAFGRCPSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANG
TH_4621|M.thermoresistible__bu DVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNG
Mflv_0405|M.gilvum_PYR-GCK DVLNVLGLYP---GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-
Mvan_0269|M.vanbaalenii_PYR-1 DVLNVLGLYP---GDPGPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQG-
*** * * * :* *.*: :* .** :*::* *
Mb1213|M.bovis_AF2122/97 CWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDDK
Rv1181|M.tuberculosis_H37Rv CWSTFVRCDARLAVTLPPELPVAAAAAVPTASATAWYALHDLARICSDDK
MLBr_01229|M.leprae_Br4923 CWTTFVICDARHAVTLSPEVPLEEAAAVPTVAATAWYGLHDLARISQTDK
MAV_1321|M.avium_104 CWGSFVLADARHAVTLPPEIPLREAAAVPTASATAWYGLHDLARIAPTDK
MMAR_2340|M.marinum_M CWATFVTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDK
MUL_2010|M.ulcerans_Agy99 CWRSYLTCDANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDR
MAB_3148c|M.abscessus_ATCC_199 AWRSFVVVDANLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDK
MSMEG_4727|M.smegmatis_MC2_155 CWSNFVTCEADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDK
TH_4621|M.thermoresistible__bu CWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEK
Mflv_0405|M.gilvum_PYR-GCK AFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDK
Mvan_0269|M.vanbaalenii_PYR-1 AFASRFNVPAQLLAPIPDGIGAVDAATIPAAALTARLAF-DWAQLKPGDR
.: . . . . :. : **: . *. .: : . : ::
Mb1213|M.bovis_AF2122/97 VLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSR
Rv1181|M.tuberculosis_H37Rv VLIHSGTGGVGQAAIAIARAAGCEIFATAGSAQRRQLLHDMGVEHVYDSR
MLBr_01229|M.leprae_Br4923 VLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIEHVYDSR
MAV_1321|M.avium_104 VLIHSGTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDMGIEHVYDSR
MMAR_2340|M.marinum_M VLIHSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSR
MUL_2010|M.ulcerans_Agy99 VLIHSATGGVGQAAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSR
MAB_3148c|M.abscessus_ATCC_199 VLIHSGTGGVGQAAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSR
MSMEG_4727|M.smegmatis_MC2_155 ILIHSATGGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSR
TH_4621|M.thermoresistible__bu VLIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSR
Mflv_0405|M.gilvum_PYR-GCK VLIHAASGGVGLAAVQMAQQCGAEVYATASTFKR-ATLRKLGVKHVYDSR
Mvan_0269|M.vanbaalenii_PYR-1 VLIHAASGGVGLAAIQMAQQHGAVVFATASTYKR-ATLRKLGVDHVYDSR
:***:.:**** **: :*: *. ::***.. * :.. *:.******
Mb1213|M.bovis_AF2122/97 STEFAEQIRGDTDGYGVDVVLNSLP-GAAQRAGIELLAFGGRFVEIGKRD
Rv1181|M.tuberculosis_H37Rv STEFAEQIRGDTDGYGVDVVLNSLP-GAAQRAGIELLAFGGRFVEIGKRD
MLBr_01229|M.leprae_Br4923 SLEFAEQIHRDTKGYGVDVVLNSLP-GAAQRAGIELLAFGGRFVEIGKRD
MAV_1321|M.avium_104 SLEFAEQIRRDTDGYGVDVVLNSLP-GAAQRAGIELLALGGRFIELGKRD
MMAR_2340|M.marinum_M SIEFAEAIRADTDGYGVDIVLNSLT-GAAQRAGLELLAWGGRFVEIGKRD
MUL_2010|M.ulcerans_Agy99 SIEFADQIRRDTNGYGVDIVLNSLT-GAAQRAGLELLAFGGRFVEIGKAD
MAB_3148c|M.abscessus_ATCC_199 STDFAELIRRDTDGYGVDIVLNSLT-GAAQRAGVELLTFGGRFIEIGKRD
MSMEG_4727|M.smegmatis_MC2_155 TTAFADQIRTDTDGYGVDIVLNSVT-GPAQRAGLELLAFGGRFVEIGKRD
TH_4621|M.thermoresistible__bu STAFADEIRRDTDGYGVDVVLNSLP-GAAQRAGLELLSFGGRFIEIGKRD
Mflv_0405|M.gilvum_PYR-GCK TTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRD
Mvan_0269|M.vanbaalenii_PYR-1 TTEFADQILADTDGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRD
: **: * **.* ***:****:. .* :. : *** *:.* *
Mb1213|M.bovis_AF2122/97 IYGDTRLGLFPFRRNLSLYAVDLALLTHSHPHTVRRLLKTVYQHTVEG--
Rv1181|M.tuberculosis_H37Rv IYGDTRLGLFPFRRNLSLYAVDLALLTHSHPHTVRRLLKTVYQHTVEG--
MLBr_01229|M.leprae_Br4923 IYGDTRLGLFPFRRNLSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEG--
MAV_1321|M.avium_104 IYRDSRLGLFPFRRNLSLFAVDLALLTHSHPHTVRRLLTTVYQRTAAG--
MMAR_2340|M.marinum_M IYGDTKMGLFPFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQHTAEG--
MUL_2010|M.ulcerans_Agy99 VYGNTRMGLYPFRRGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEG--
MAB_3148c|M.abscessus_ATCC_199 IYGDTRLGLFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEG--
MSMEG_4727|M.smegmatis_MC2_155 IYADTRLGLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADG--
TH_4621|M.thermoresistible__bu IYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADG--
Mflv_0405|M.gilvum_PYR-GCK IWTVEQMAAA--RPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG--
Mvan_0269|M.vanbaalenii_PYR-1 IWTPEQMAAA--RPDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADG
:: ::. * .:: * * : .* : * : .
Mb1213|M.bovis_AF2122/97 ----TLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVP
Rv1181|M.tuberculosis_H37Rv ----TLPVPQTTHYPIHDAAVAIRLVGGAGHTGKVVLDVPRTGEGVAVVP
MLBr_01229|M.leprae_Br4923 ----VLPVPQTTHYPIHNTANAVRLVAGAGHTGKVLLDVPHTGSSVAVVP
MAV_1321|M.avium_104 ----ELPMPRTTHYPLQDAVAAVRLVAAAGHTGKVVLQVPRTASSVAALP
MMAR_2340|M.marinum_M ----VLPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLP
MUL_2010|M.ulcerans_Agy99 ----VLSAPECTHYPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVP
MAB_3148c|M.abscessus_ATCC_199 ----VLPLPEISPSPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIP
MSMEG_4727|M.smegmatis_MC2_155 ----TLPLPEITHYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVP
TH_4621|M.thermoresistible__bu ----VLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVP
Mflv_0405|M.gilvum_PYR-GCK ----AWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP-----
Mvan_0269|M.vanbaalenii_PYR-1 SSRAEWVPLPAEIYPLTEARAAFRRMQQARHVGKIVLQMPKPLQP-----
*: :: :.* : * * **:::::* .
Mb1213|M.bovis_AF2122/97 PEQVRTSRPDGAYLVTGGLGGLGLFLAGELAA----AGCGRIVLNSRSTP
Rv1181|M.tuberculosis_H37Rv PEQVRTSRPDGAYLVTGGLGGLGLFLAGELAA----AGCGRIVLNSRSTP
MLBr_01229|M.leprae_Br4923 PEQVRTFRADGAYIVTGGLTGLGLFLGTEMAA----AGCGRIVLNSRSAP
MAV_1321|M.avium_104 PEKVRPFRADGAYIITGGLGGLGLFLAGEMASRDGDVGAGRIVLNSRSQP
MMAR_2340|M.marinum_M PEQVPVLRADGSYIITGGLGGLGLFLAEKMAT----AGAGRIVLSSRSAP
MUL_2010|M.ulcerans_Agy99 PEQVEVFRGDGSYIITGGLGGLGLFFASKMAA----AGCGRIVLTARSQP
MAB_3148c|M.abscessus_ATCC_199 PSHAPAFRRDGAYVVTGGLGGLGLFLARKLAA----AGVGRIILNGRSAP
MSMEG_4727|M.smegmatis_MC2_155 PEQVPVFRGDGAYVITGGLGGLGLFLAERMAA----AGCGRIVVNSRSAP
TH_4621|M.thermoresistible__bu PEQASPFRSDGAYIVTGGMGGLGLYLAGEMAA----AGAGCIVLNGRSAP
Mflv_0405|M.gilvum_PYR-GCK -------QPDRSYLITGGLGAIGLHTAGYLAQ----LGAGDIVLTSRRAP
Mvan_0269|M.vanbaalenii_PYR-1 -------RADRSYLITGGLGAIGLHTAAYLAQ----LGAGDLVLTSRRAP
: * :*::***: .:**. . :* * * :::..* *
Mb1213|M.bovis_AF2122/97 SPHATRVIERLRA-AGADIQVECGDIADAATAHRVVAVATASGLPVRGVL
Rv1181|M.tuberculosis_H37Rv SPHATRVIERLRA-AGADIQVECGDIADAATAHRVVAVATASGLPVRGVL
MLBr_01229|M.leprae_Br4923 NPQAQETIERLRA-GGADIQVECGDIAEPRVADRLVVAATQSGLPVRGVL
MAV_1321|M.avium_104 GEQARRAIERLRA-AGADIAVECGDIAQPDTAERLVTCATATGLPVRGVL
MMAR_2340|M.marinum_M SQKALETIELIRS-IGSDVVVECGDIAQPATAARLVANATATNLPLRGVL
MUL_2010|M.ulcerans_Agy99 NPKSRQAIERLRA-NGADIVVECGNIAEPETADRLVSAATATGLPLRGVL
MAB_3148c|M.abscessus_ATCC_199 KPEALAAIEQIRQ-GGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVL
MSMEG_4727|M.smegmatis_MC2_155 STRSSEIIELIRA-TGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVL
TH_4621|M.thermoresistible__bu SGEALRTIEQLRA-AGTEVIVECGXX----XRGQPVEVAVPT------EL
Mflv_0405|M.gilvum_PYR-GCK DAAAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVA
Mvan_0269|M.vanbaalenii_PYR-1 DADARRAIEEITERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVA
: * : : . . :
Mb1213|M.bovis_AF2122/97 HAAAVVEDATLANVTDELIDR-CWAPKVHGAWNIHRAT-----AAQPLEW
Rv1181|M.tuberculosis_H37Rv HAAAVVEDATLANVTDELIDR-CWAPKVHGAWNIHRAT-----AAQPLEW
MLBr_01229|M.leprae_Br4923 HAAGVVEDATLTNVTDDLIDR-CWAPKVYGAWNLHQALQEG-KTAQLLDW
MAV_1321|M.avium_104 HAAAVVEDATLTNVTDDLIDR-CWAPKVYGAWNLHQAT-----AGQPLEW
MMAR_2340|M.marinum_M HAAAVVEDATLANITDELLDR-DWAPKVYGAWHLHQAT-----TDQPLDW
MUL_2010|M.ulcerans_Agy99 HAAAVVEDATLSNITDELIDR-DWSPKVYGSWNLHRAS-----TGQPLDW
MAB_3148c|M.abscessus_ATCC_199 HAAALVHDATLANITDELIDRGDWRPKVHGAWNLHEAT-----ADQPLDW
MSMEG_4727|M.smegmatis_MC2_155 HAAAVVEDATLANITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDW
TH_4621|M.thermoresistible__bu RHADEHPDRRGAQLCDEFARG------EQGAQRNQHRT------DAGEGQ
Mflv_0405|M.gilvum_PYR-GCK HLAGVLDDALLSQQSVERFRT-ALAPKAFGAVHLDRLT-----RVDDLDF
Mvan_0269|M.vanbaalenii_PYR-1 HLAGVLDDALLSQQSLERFRT-TLAPKAFGACHLDRLT-----AGDDLDF
: * * :: : *: . ..
Mb1213|M.bovis_AF2122/97 FCLFSSAAALVGSPGQGAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAE
Rv1181|M.tuberculosis_H37Rv FCLFSSAAALVGSPGQGAYAAANSWLDAFAHWRRAQGLPATSIAWGAWAE
MLBr_01229|M.leprae_Br4923 FCSFSTAAALVGSPGQGAYAAANSWLDGFSYWRRAQGLASTTIAWGAWGE
MAV_1321|M.avium_104 FCLFSSAAALVGSPGQGAYAAANSWLDAFARWRHARGAPATAIAWGAWSQ
MMAR_2340|M.marinum_M FCSFSSAAAMLGSPGQGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAE
MUL_2010|M.ulcerans_Agy99 FCLFSSGAALMGSPGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGE
MAB_3148c|M.abscessus_ATCC_199 FCSFSSIAALVGSPGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSE
MSMEG_4727|M.smegmatis_MC2_155 FCAFSSAAALVGSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGE
TH_4621|M.thermoresistible__bu RDAHPPGAVGHDQPDPGALSDTG--LDERGGQFPGVGVQIPVADPG----
Mflv_0405|M.gilvum_PYR-GCK FLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWAR
Mvan_0269|M.vanbaalenii_PYR-1 FIMSSSVSSLFGSPGQANYATANALLDGLTAHRRARGLPATGVNFGPWAQ
.. : ..*. . : :. :* . *
Mb1213|M.bovis_AF2122/97 IGRATALAEGT---GAAIAPAEGARAFQTLLRYGRAYSGYAPIMGTPWLT
Rv1181|M.tuberculosis_H37Rv IGRATALAEGT---GAAIAPAEGARAFQTLLRYGRAYSGYAPIMGTPWLT
MLBr_01229|M.leprae_Br4923 LGLATALAEMA---GVAIAPTEGARVFQTLLRYNRPYSCYAPIMETPWLK
MAV_1321|M.avium_104 VGRATALAEDA---GVAITPTEGFRAFETLLRHDRPYAGYAPIMGTPWLT
MMAR_2340|M.marinum_M IGRAIALAESS---DAAIAPDEGAYAFQTLLRHNRTYTGYAPIIGAPWVT
MUL_2010|M.ulcerans_Agy99 VGRATFLAEGG---EIMIAPDEGMYAFEQMLRHARTYTGYIPIIGAPWLA
MAB_3148c|M.abscessus_ATCC_199 IGQGTHLAQNA---EAAILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLA
MSMEG_4727|M.smegmatis_MC2_155 IGRGTAMAEG----DNAIAPDEGAYAFEAILRHDRVYNGYAPVLGASWLT
TH_4621|M.thermoresistible__bu VGIDHRGAVRV---DSGVPAQQGVDG--EVVRHRTLSS------------
Mflv_0405|M.gilvum_PYR-GCK GGMASSEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQR
Mvan_0269|M.vanbaalenii_PYR-1 GGMASSEAATANIGAQGLVPLEPSAALGALAEVLANGTGQAAVLKANWQR
* * : . : : .
Mb1213|M.bovis_AF2122/97 AFAQRSRFAE-----AFHATGQNQPATGKFLAELGSLPREEWPRTVRRLV
Rv1181|M.tuberculosis_H37Rv AFAQRSRFAE-----AFHATGQNQPATGKFLAELGSLPREEWPRTVRRLV
MLBr_01229|M.leprae_Br4923 SFAQHSRFAE-----AFRSISQGQKDKSKFLAELKVLPRDEWPSMIRRLV
MAV_1321|M.avium_104 SFAQRSPFAE-----AFRSAGQGRPDAGKFLAELRALPREEWPSAIRRLV
MMAR_2340|M.marinum_M AFAERSKFAE-----AFKALEQGRSGSSKFRSELDALPLDEWPGQLRRMV
MUL_2010|M.ulcerans_Agy99 DLVRRSPWAE-----MFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLI
MAB_3148c|M.abscessus_ATCC_199 DFVERSPFAQ-----AFRDAGQNQTETNKFLDELRALPREEWPTRLRKLV
MSMEG_4727|M.smegmatis_MC2_155 AFAQRSPFAE-----LFLADTQGASETRKLRSELAALPREEWPTHLRRLI
TH_4621|M.thermoresistible__bu ---VRSGRSS-----RWTAPGSRCGSGRRYGGES----------------
Mflv_0405|M.gilvum_PYR-GCK AAKVLGSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFL
Mvan_0269|M.vanbaalenii_PYR-1 AAKVLGSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFL
. . :
Mb1213|M.bovis_AF2122/97 SDQISLLLRRTIDPDRP--LSDYGLDSLGNLELRTRIETETG--IRVSPT
Rv1181|M.tuberculosis_H37Rv SDQISLLLRRTIDPDRP--LSDYGLDSLGNLELRTRIETETG--IRVSPT
MLBr_01229|M.leprae_Br4923 SEQISLLLRRTIDPDRL--LSDYGLDSLGNLELRTRIETETG--IRISPT
MAV_1321|M.avium_104 SGQLSLLLRRTIDPDRP--LSDYGLDSLGNLELRTRIETETG--VRISPA
MMAR_2340|M.marinum_M AEQVSLILRRTIDPDRQ--LSEYGLDSLGNLELRTRVQSETG--IRISST
MUL_2010|M.ulcerans_Agy99 AEQASVILRRTVDADRP--FVEYGLDSLGMLEMRTHIETETG--VRLSPK
MAB_3148c|M.abscessus_ATCC_199 AEQVGLVLRRSIDPDRS--LPDYGLDSLGNLEIRTRIQADTG--VRIGPA
MSMEG_4727|M.smegmatis_MC2_155 AEQVGLLLRRTVDPDRP--LSEYGLDSLGHLELRTRIETETG--VRVSAM
TH_4621|M.thermoresistible__bu -------CRRTTGP------------AAGAAARRGRTRRRRR--PRRPPP
Mflv_0405|M.gilvum_PYR-GCK QKEVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINAT
Mvan_0269|M.vanbaalenii_PYR-1 QREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINAT
* : . : * : . .
Mb1213|M.bovis_AF2122/97 KIT---TVRGLAEHVCDELAAAQSAPV-----------------------
Rv1181|M.tuberculosis_H37Rv KIT---TVRGLAEHVCDELAAAQSAPV-----------------------
MLBr_01229|M.leprae_Br4923 KIT---TIRSLAEHLCEELAATEAESAVTAT-------------------
MAV_1321|M.avium_104 TIT---TVRGLAEHLCDELADLPAAPPAGAPR------------------
MMAR_2340|M.marinum_M DIT---TVRGLADHLFAQLAPEEAAASSQ---------------------
MUL_2010|M.ulcerans_Agy99 VIASHNTARALSQHLADTLAEEEAQPAAS---------------------
MAB_3148c|M.abscessus_ATCC_199 DVS---TVRSLAAHIYDRLAEQESEVASS---------------------
MSMEG_4727|M.smegmatis_MC2_155 DMT---TIRGLAQRLCEMLDTDDAVSAPS---------------------
TH_4621|M.thermoresistible__bu PPD---RVRHRAGPAHGPVRR-----------------------------
Mflv_0405|M.gilvum_PYR-GCK AVFDYPTIGGLAEYLVAQLPD-----AETPQAAPQSESEPGPDVTE----
Mvan_0269|M.vanbaalenii_PYR-1 AVFDYPTIGGLAEYLVGQLPDSDAAAGETPATETSPIDHNHPDREADSPG
: :