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MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPCVGILQQVISRPGDIPQALTETARSFTNPGQ PAPPVVRPPASSSSSVGTPPVPPTPPGSVVRPSSGATPPVPPTPGTPASTTTGVGTPPVPPTPPGSTVRP AAGATPPAPPVPGVPAGTPIGGGTPPLPPVPGAPAGTPVANVAPPSPPVPGVPVIGDGGAALPPLPPVPG GPAAVPAGVVTPPAPPIPGGPAAMPAGVAAPPAPAPPGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGP GGGAGAPGAPVAAAAGNAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGLVAPPGPPAPGVPVVDQAG VVAPPGPPAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVP VVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPGAPGVPVDGGAELVTPPGPGAPGTPTVSSVETFSPPAP PAPGTPSSGSIETFSPPAPPTPGTPANSSVEIVTPPPPGVPGVPGEGSTTYTTPPTPEITLNPANSSIDV ATPPGPGVPGVPVEASANVSTPPVPGVPGAPVNSSVEVATPAEVGVPGTPIERSTTLTTPPTPGVPGTPV NSSVEVATPPAPGAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPG APGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVV TPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPPAAAPGAPIDAAAASVAPSGPPAAPVL GEAGVVAPPAPPGGGAPGGGAPGAGVGTGAPIEGAAGAGGVPAAPLAANAGAATPPAAATGGAGAPIDAA AGAAAPPAPPAPGAPIFGEAGVAAPPLPPAPGGAGAVPAGVVTPPVPGVPGGAGAVPAGAVTPPTPPVPG SSSGGFVNYPAPPVPPTPPNSAGVNTGTPGSPIPGTPGSTLTISDLLTPPGVARTVQNTASSVMSIAPPG TPPVPGGAGSVSVGVPAPPSPLTPLAATGLSNLVSPPSLTIPSIPGLPVPLPNEVPVPSDLLCVGTDWSA TQGDSATTPVNAEIPRALVTGAAPVGDRRDRWDTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2552 | - | - | 100% (1155) | hypothetical protein Mvan_2552 |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | 3e-38 | 33.56% (447) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 3e-23 | 30.46% (371) | FHA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3909c | - | 1e-28 | 32.35% (374) | hypothetical protein Mb3909c |
| M. gilvum PYR-GCK | Mflv_3843 | - | 0.0 | 66.01% (1265) | hypothetical protein Mflv_3843 |
| M. tuberculosis H37Rv | Rv3879c | - | 5e-26 | 33.13% (323) | hypothetical protein Rv3879c |
| M. leprae Br4923 | MLBr_01556 | infB | 6e-13 | 33.02% (212) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_3131c | - | 3e-18 | 32.59% (270) | translation initiation factor IF-2 (InfB) |
| M. marinum M | MMAR_5451 | - | 2e-41 | 29.06% (640) | hypothetical protein MMAR_5451 |
| M. avium 104 | MAV_4827 | - | 2e-25 | 31.58% (323) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 2e-26 | 33.33% (399) | secreted protein |
| M. thermoresistible (build 8) | TH_4426 | - | 1e-34 | 35.66% (272) | PUTATIVE AAA ATPase |
| M. ulcerans Agy99 | MUL_1004 | - | 3e-21 | 30.25% (367) | hypothetical protein MUL_1004 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3909c|M.bovis_AF2122/97 --MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDT
Rv3879c|M.tuberculosis_H37Rv --MSITRPTGSYARQMLDPGGWVEADEDTFYDRAQEYSQVLQRVTDVLDT
Mvan_2552|M.vanbaalenii_PYR-1 ----MSRTKKSIVVVMMGSAGLFLSAPLLGPSANATPTRGGVPCVGILQQ
Mflv_3843|M.gilvum_PYR-GCK ----MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQ
MLBr_01556|M.leprae_Br4923 -MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRE
MAB_3131c|M.abscessus_ATCC_199 -MAGKARVHELAKELGVTSKEVLARLSDQGEFVKSASSTVEAPVARRLRE
MUL_1004|M.ulcerans_Agy99 ---------------------------------MASTWSLSKGLAAVVVT
MSMEG_5700|M.smegmatis_MC2_155 ---------------------------MSGRHRKPTSSSSAKNVAKIAFT
MMAR_5451|M.marinum_M MPADYDELFQPAEGSGPPDDETGQTFFDPGTAYPPPVKPNGDGHSAPKDW
TH_4426|M.thermoresistible__bu ------VVRPAHPLYCAAVRAELTEPEVRGVRTELAGAAAPTDVVGRLRW
MAV_4827|M.avium_104 MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR
Mb3909c|M.bovis_AF2122/97 CRQQKGHVFEGGLWSGGAANAAN-------GALGANINQLMTLQDYLATV
Rv3879c|M.tuberculosis_H37Rv CRQQKGHVFEGGLWSGGAANAAN-------GALGANINQLMTLQDYLATV
Mvan_2552|M.vanbaalenii_PYR-1 VISRPGDIPQALTETARSFTNPG-------QPAPPVVRPPASSSSSVGTP
Mflv_3843|M.gilvum_PYR-GCK IVTRPGEIPQALTDTARSFTEPP-------KPAPPVVRPPASSSSSAGTP
MLBr_01556|M.leprae_Br4923 SFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAA
MAB_3131c|M.abscessus_ATCC_199 SFGGGDKPAPAASNGAAAEAAAP-------------PKKAGPKPGAPKPA
MUL_1004|M.ulcerans_Agy99 SAAAFGLCPAAAADPAAPQPNPN--------PQLPGLPALAQLSPIIQQA
MSMEG_5700|M.smegmatis_MC2_155 GAVLGGGGLGMAGQAMAATDGEW--------------DQVARCESGGNWA
MMAR_5451|M.marinum_M SRAFPPAEDESPSDSAEPAAGPAKSPLPPMPIGGPAPTPPEPPPAPPELP
TH_4426|M.thermoresistible__bu TLHALDSDAPPAAQQLTVAAEDALRLGDLGLCERFGRAAVGAAGSGAGLA
MAV_4827|M.avium_104 VISAILGTREGAADAGLQLSSIG-------VTWTDQLEAAALRDALAARR
Mb3909c|M.bovis_AF2122/97 ITWHRHIAGLIEQAKSDIG--NNVDGAQREIDILENDPSLDADE-----R
Rv3879c|M.tuberculosis_H37Rv ITWHRHIAGLIEQAKSDIG--NNVDGAQREIDILENDPSLDADE-----R
Mvan_2552|M.vanbaalenii_PYR-1 PVPPTPPGSVVRPSSGATPPVPPTPGTPASTTTGVGTPPVPPTP-----P
Mflv_3843|M.gilvum_PYR-GCK PVPGRPPASVVTPSSGATPPVPPSPGTPASTSTRGGTPPVPPAP-----P
MLBr_01556|M.leprae_Br4923 PVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPG-----Q
MAB_3131c|M.abscessus_ATCC_199 PKKVAEPVVEAPVAP-EPPAAPAAPAAPAPKPSPAARPAAAEAA-----A
MUL_1004|M.ulcerans_Agy99 AGNPEQATQLLMAAAQAFAHNPAAPTESRNVASSVNQFVQEPVN-----P
MSMEG_5700|M.smegmatis_MC2_155 INTGNGYHGGLQFSPSTWRAHGGTEFAPAAYMATKEE-QIAVAE-----R
MMAR_5451|M.marinum_M PAPPEPPPARPEAPPQAPTAEAEPPDEAIPVSGPPPGGKSPLPP-----M
TH_4426|M.thermoresistible__bu ARLPLAYALAFQGRGREADEVLAAVDSTGLTEHELMAWALPRAANQFWML
MAV_4827|M.avium_104 IDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVV-----E
Mb3909c|M.bovis_AF2122/97 HTAINSLVTATHGANVSLVAETAERVLESKNWKPPKNALEDLLQQKSPPP
Rv3879c|M.tuberculosis_H37Rv HTAINSLVTATHGANVSLVAETAERVLESKNWKPPKNALEDLLQQKSPPP
Mvan_2552|M.vanbaalenii_PYR-1 GSTVRPAAGATPPAPPVPGVPAGTPIGGGTPPLPPVPGAPAGTPVANVAP
Mflv_3843|M.gilvum_PYR-GCK APAGTPASGATPPAPPVPGVPAVTSTGGGTPPVPPVPGAPVGAPVANPGL
MLBr_01556|M.leprae_Br4923 QGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPR
MAB_3131c|M.abscessus_ATCC_199 PAPAPAPAP-RPGATPGPKPG-AP----RVPRVGNNPFSSAQPAERPAPR
MUL_1004|M.ulcerans_Agy99 APGSPPLGVPAPAAAPVEVAPPASAPVPHVPAPGAEPGTLAHLPAG----
MSMEG_5700|M.smegmatis_MC2_155 VLASQGKGAWPTCGRGLSGATPRNVVAEPEPAPLDAPGVNGELPP-----
MMAR_5451|M.marinum_M PIGGPPPASPEPPAAPPEPTAPAEPPQPPEAAAQPPQAVEEQAHATAEPP
TH_4426|M.thermoresistible__bu SQPERAVAFLRTVRERVSSPTAATTLDALSATFAMNAGRPQQALQTATEV
MAV_4827|M.avium_104 TSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGV
Mb3909c|M.bovis_AF2122/97 PDVPTLVVPSPGTPGTPGTPGTPITPGTPITPGTPITPGTPITPG-----
Rv3879c|M.tuberculosis_H37Rv PDVPTLVVPSPGTPGTPGTP---------------ITPGTPITPG-----
Mvan_2552|M.vanbaalenii_PYR-1 PSPPVPGVPVIGDGGAALPPLPPVPGGPAAVPAGVVTPPAPPIPGGPAAM
Mflv_3843|M.gilvum_PYR-GCK PTPPVPGAPVFGDGGAVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAV
MLBr_01556|M.leprae_Br4923 PPAPRP------SASPSSMSPRPGGAVGGGGPRPPRTG-VPRPGGGRPGA
MAB_3131c|M.abscessus_ATCC_199 PQAPRPGAPRPGGASPSNMPPRP--SPGSMGPRPPRPGGGPRPGGGPRPG
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M AAPNPPRPPMPIGGPPPTPPAAPEPQQDIAEEPAPAAAEAP---------
TH_4426|M.thermoresistible__bu LASPTADGTAIGWAGAAAALSAARMGRFTEVDALAERAMSAGHPGLLRFT
MAV_4827|M.avium_104 DVAPLKQVLQTTTFLDVSVAEEPETALAR---------------------
Mb3909c|M.bovis_AF2122/97 --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 PAGVAAPPAP-APPGAPIFGEAGAVPPPGVGGAPLDGASGVAAPGGPGGG
Mflv_3843|M.gilvum_PYR-GCK PAGVALPPAPPGAPGAPVFGEAGAAPSGAAAPVAPAAGSGGAGGAGGGSG
MLBr_01556|M.leprae_Br4923 PVG-----------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 GAG-----------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_4426|M.thermoresistible__bu SGFG----------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 --------------------------------TPITPIPGAPVTPIT---
Rv3879c|M.tuberculosis_H37Rv --------------------------------TPITPIPGAPVTPIT---
Mvan_2552|M.vanbaalenii_PYR-1 AGAPGAPVAAAAGNAGPPAPGAPVGDQAGVVAPPAPPAPGAPVGDQAGLV
Mflv_3843|M.gilvum_PYR-GCK IGGPGGGGAPVEGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVV
MLBr_01556|M.leprae_Br4923 --------------------------------GRSDAGGGNYRGGGVG-A
MAB_3131c|M.abscessus_ATCC_199 --------------------------------RPGGGGGGNYRGGGTGTG
MUL_1004|M.ulcerans_Agy99 -------------------------------IDPAHAAGPAPVAAPAG--
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------PAPVDMLAAPMPAPEG--
MMAR_5451|M.marinum_M ------------------------------AAPPKSPLPPMPVSGPPP--
TH_4426|M.thermoresistible__bu -------------------------------QTTARQLTGAPDQALALAR
MAV_4827|M.avium_104 --------------------------------GAALAAANAPLFASST--
Mb3909c|M.bovis_AF2122/97 ----------------------------------------PTPGTP----
Rv3879c|M.tuberculosis_H37Rv ----------------------------------------PTPGTP----
Mvan_2552|M.vanbaalenii_PYR-1 APPGPPAPGVPVVDQAGVVAPPGPPAPGVPVVDEAGVVTPPGPGAPGVPV
Mflv_3843|M.gilvum_PYR-GCK PPPAPPAPAPPAGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPT
MLBr_01556|M.leprae_Br4923 LPGGGS----------------------------GGFRGRPGGGGHGGGG
MAB_3131c|M.abscessus_ATCC_199 APAGGPPGA------------------------GGGFRGRPGGG--GGGG
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_4426|M.thermoresistible__bu --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 ------VTPVTPGKP----------VTP----------------VTPVKP
Rv3879c|M.tuberculosis_H37Rv ------VTPVTPGKP----------VTP----------------VTPVKP
Mvan_2552|M.vanbaalenii_PYR-1 VGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPGP
Mflv_3843|M.gilvum_PYR-GCK GGEGGVVTPPAPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAP
MLBr_01556|M.leprae_Br4923 RPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGN
MAB_3131c|M.abscessus_ATCC_199 RPGQRGGAAGAFGRPGGAPKRGRKSKRAKRAEYENMQAPVVGGVRLPHGN
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M ------EPPELPPAPPEPTASAEPPQPPQSVEEQAHATAEPPAAPKPTRP
TH_4426|M.thermoresistible__bu ---------------------------------------RLTEIAQLQQP
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 G-----TPGEPTP-----ITPVTPP------------VAPATPATPATPV
Rv3879c|M.tuberculosis_H37Rv G-----TPGEPTP-----ITPVTPP------------VAPATPATPATPV
Mvan_2552|M.vanbaalenii_PYR-1 G-----APGVPVVDEAGVVTPPAPGAPGVPVDGGAELVTPPGPGAPGTPT
Mflv_3843|M.gilvum_PYR-GCK G-----APGAPVVDEAGVVTPPAPGGPGVPAVGDTAVVTPPAPGAPGTPA
MLBr_01556|M.leprae_Br4923 GETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLEL
MAB_3131c|M.abscessus_ATCC_199 GEVIRLARGASLSDFAEKIDANPASLVQALFNLGEMVTATQSVGDETLEL
MUL_1004|M.ulcerans_Agy99 ----------------------------------------APPASAPAPA
MSMEG_5700|M.smegmatis_MC2_155 ----------------------------------------LPPAPEALPP
MMAR_5451|M.marinum_M P----MPIGGPPPTPEPQQGAPQPHQDIAEEPNPAAAEAPAAPPKSPRPP
TH_4426|M.thermoresistible__bu G-----RAIGELLIAEVLITRGDLDEAVALLRAAVKVLTPTGYSWAPLAA
MAV_4827|M.avium_104 ----------------------------------AALAYAQDPGTGAVDQ
Mb3909c|M.bovis_AF2122/97 TPAPAPHPQPAPAPAPSPG---------PQPVTPATPG--------PSGP
Rv3879c|M.tuberculosis_H37Rv TPAPAPHPQPAPAPAPSPG---------PQPVTPATPG--------PSGP
Mvan_2552|M.vanbaalenii_PYR-1 VSSVETFSPPAPPAPGTPSSGSIETFSPPAPPTPGTPANSSVEIVTPPPP
Mflv_3843|M.gilvum_PYR-GCK VNSVETFSPPAPPAATPPSSGSVETFSPPAPPAPGTGTNSTVEISTPPPP
MLBr_01556|M.leprae_Br4923 LGSEMNYNVQVVSPEDEDRE-----LLEPFDLTYGEDQGDEDELQVRPPV
MAB_3131c|M.abscessus_ATCC_199 LGGEMNYVVQVVSPEDEDRE-----LLESFDLTYGEDEGGEEDLRTRPPV
MUL_1004|M.ulcerans_Agy99 AAAPASAPGTAPAPAAAPG-------------------------------
MSMEG_5700|M.smegmatis_MC2_155 APEALPPAPEAPAPAPEALP------------------------------
MMAR_5451|M.marinum_M MPVNGPAPTRPEPPLPPGPPRRRAQPPTAPPNQPGQPKPISGHPPPPPRP
TH_4426|M.thermoresistible__bu MLLARALGEQGAAPEAAIALSRAESRHGLKSMLFAPELALARAWTRAARG
MAV_4827|M.avium_104 YSLPDYLYVPVDPEPGDDELAYS---------------------------
.
Mb3909c|M.bovis_AF2122/97 ATPGTPGGEPAPHVKP----------------------------------
Rv3879c|M.tuberculosis_H37Rv ATPGTPGGEPAPHVKP----------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 GVPGVPGEGSTTYTTPPTPEITLNPANSSIDVATPPGPGVPGVPVEASAN
Mflv_3843|M.gilvum_PYR-GCK GTPGLPSEGSTTYTTPPTPEITLNPANSGIDIATPPAPGLPGAPLEATAN
MLBr_01556|M.leprae_Br4923 VTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERL
MAB_3131c|M.abscessus_ATCC_199 VTVMGHVDHGKTRLLDTIRKANVREGEAGGITQHIGAYQVAVEHDGTERP
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M AAFAPPARGATPNRHESAEPPPPRRVRIGGPPQPPGPP------------
TH_4426|M.thermoresistible__bu DRHGAVXXXXACWWWRWWDXX-----------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 AALAEQPGVPGQHAGG--------------------------GTQSGPAH
Rv3879c|M.tuberculosis_H37Rv AALAEQPGVPGQHAGG--------------------------GTQSGPAH
Mvan_2552|M.vanbaalenii_PYR-1 VSTPPVPGVPGAPVNSSVEVATPAEVGVPGTPIERSTTLTTPPTPGVPGT
Mflv_3843|M.gilvum_PYR-GCK ITTPGTPGVPGAPVNSSIDVATPGEVGVPAAPIERSMTVTTPDTPGAPGA
MLBr_01556|M.leprae_Br4923 ITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAA
MAB_3131c|M.abscessus_ATCC_199 ITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAA
MUL_1004|M.ulcerans_Agy99 ------------------------------------------PAPAAPAP
MSMEG_5700|M.smegmatis_MC2_155 ------------------------------------------PAPEALPP
MMAR_5451|M.marinum_M -EAESEAPRHSRHARRTHRYRPEPETDDLEATAVRPLPTREPMRRNGPAA
TH_4426|M.thermoresistible__bu ------------------------------------------TPPGPPAP
MAV_4827|M.avium_104 ------------------------------------------AVGEEDAE
Mb3909c|M.bovis_AF2122/97 ADESAASVTPAAASGVPGARAAAAAPSG--TAVGAGAR-------SSVGT
Rv3879c|M.tuberculosis_H37Rv ADESAASVTPAAASGVPGARAAAAAPSG--TAVGAGAR-------SSVGT
Mvan_2552|M.vanbaalenii_PYR-1 PVNSSVEVATPPAPGAPGVPVVDEAGVV--TPPGPGAPGVPVVGEAGVVT
Mflv_3843|M.gilvum_PYR-GCK PANAAVDVATPPAPGVPGAPVVGEAGVT--TPGAPGAPGAPANAAVDVAT
MLBr_01556|M.leprae_Br4923 DVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGT
MAB_3131c|M.abscessus_ATCC_199 DVPIVVAVNKIDKEGADPAKIRAQLTEYNLVAEDFGGDTMFVDISARQGT
MUL_1004|M.ulcerans_Agy99 APAAAAPAPAPAPAAPPAAPVAAPVAAP-----------------APVPA
MSMEG_5700|M.smegmatis_MC2_155 APEALPPAPEAPAPAPEALPPAPEAPAP----------------VAEALP
MMAR_5451|M.marinum_M DESSTASFAWLQQSQPTLDRPSGPMPAAPGAPVESAPGRADGRRARRRAE
TH_4426|M.thermoresistible__bu PAGGGGGGDVETPPGPPAPPAEVEERDD-------------------AEI
MAV_4827|M.avium_104 SPTVVIEKLFLPEDSEPRRRPVLLVGSG----------------LAVVGI
Mb3909c|M.bovis_AF2122/97 AAASGAGSHAATGRAPVATSDKAAAPSTRAASAR---TAPPARPPSTDHI
Rv3879c|M.tuberculosis_H37Rv AAASGAGSHAATGRAPVATSDKAAAPSTRAASAR---TAPPARPPSTDHI
Mvan_2552|M.vanbaalenii_PYR-1 PPGPGAPGVPVVDEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVV
Mflv_3843|M.gilvum_PYR-GCK PPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPVV
MLBr_01556|M.leprae_Br4923 NIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQR
MAB_3131c|M.abscessus_ATCC_199 NIEQLLEAVLLTADAALDLRANPDMEAQGVAIEAHLDRGRGPVATVLIQR
MUL_1004|M.ulcerans_Agy99 PAPAAAPAPEAAAPAPAPAPAPAAAPG------------FGPDAPPTQDF
MSMEG_5700|M.smegmatis_MC2_155 PAPEALPPAPEAPPAPEALPPAPEAQIVDASLQVPADVPPAPPVEPAPPA
MMAR_5451|M.marinum_M SRTSAASTPSPLVPTRAQPPGPTRAQPPRTAAPAQPATEPLPDAGAPAEQ
TH_4426|M.thermoresistible__bu PPGPPSPPAGGGGGGEIAPPPTPGEPGAVIDQSSQNVTVPAPPTPGSETS
MAV_4827|M.avium_104 SAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQP
.
Mb3909c|M.bovis_AF2122/97 DKPDRSESADDGTP--------VSMIPVSAARAARDAATAAASARQRGRG
Rv3879c|M.tuberculosis_H37Rv DKPDRSESADDGTP--------VSMIPVSAARAARDAATAAASARQRGRG
Mvan_2552|M.vanbaalenii_PYR-1 DEAGVVTPPGPGAPGVPVVGEAGVVTPPGPGAPGVPVVDEAGVVTPPGPG
Mflv_3843|M.gilvum_PYR-GCK GEAGVTTPGAPGVPGVPAGGDAGVVTPPAPGVPGAPAATEAGLATPPGPG
MLBr_01556|M.leprae_Br4923 GTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAG
MAB_3131c|M.abscessus_ATCC_199 GTLRVGDSIVAGDAYGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAG
MUL_1004|M.ulcerans_Agy99 MYPSIGTN-----------------CLADGSNIIATALSVAGPATIPTPG
MSMEG_5700|M.smegmatis_MC2_155 PVDAVAAPENQNWD----------QAPAPADQPQTWALHVGGPLP-----
MMAR_5451|M.marinum_M SKKPNKPVPQRGWRRWVYAVTRINFGLSPDEKYELDLRTRIGRKPRGSYQ
TH_4426|M.thermoresistible__bu TALEVFSPPVPPGEVSGGGSNMLELPGFPGGTIGGPEIAHNVEVTGPPAE
MAV_4827|M.avium_104 KISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPV
Mb3909c|M.bovis_AF2122/97 DALRLARRIAAALNASDNNAGDYGFFWITAVTT-----------------
Rv3879c|M.tuberculosis_H37Rv DALRLARRIAAALNASDNNAGDYGFFWITAVTT-----------------
Mvan_2552|M.vanbaalenii_PYR-1 APGVPVVDEAGVVTPPGPGAPGVPVVDEAGVVTPPAPPAAAPGAPIDAAA
Mflv_3843|M.gilvum_PYR-GCK APGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAP-----VAPVEGAG
MLBr_01556|M.leprae_Br4923 DNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLED-----------
MAB_3131c|M.abscessus_ATCC_199 DNLLVVDEDRIARQIADRRSARKRNALAARSRKRISLDD-----------
MUL_1004|M.ulcerans_Agy99 ---------------PGPG-------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M IAILGLKGGAGKTTTTVTLGTTLTHVRGDRILVLDADP------------
TH_4426|M.thermoresistible__bu ASVPGVDASVATEAGTPPVPPGP---------------------------
MAV_4827|M.avium_104 VVPPVPVPVPVRIPVPDPVSPPQ---------------------------
Mb3909c|M.bovis_AF2122/97 --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 ASVAPSGPPAAPVLGEAGVVAPPAP-----------PGGGAPGGGAPGAG
Mflv_3843|M.gilvum_PYR-GCK GAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVAGAGAGGG
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_4426|M.thermoresistible__bu --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 --------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 VG---TGAPIEGAAGAGGVPAAPLAANAGAAT---PPAAATGG-------
Mflv_3843|M.gilvum_PYR-GCK AGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGGPVAGGGP
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_4426|M.thermoresistible__bu --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 ---------DGSIVVANS--------------------------------
Rv3879c|M.tuberculosis_H37Rv ---------DGSIVVANS--------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 ---------AGAPIDAAAGAAAPPAP----------------PAP---GA
Mflv_3843|M.gilvum_PYR-GCK VGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPPAPGVPGA
MLBr_01556|M.leprae_Br4923 ---------LDSALKETS--------------------------------
MAB_3131c|M.abscessus_ATCC_199 ---------LDAALKETS--------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5451|M.marinum_M --------------------------------------------------
TH_4426|M.thermoresistible__bu --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb3909c|M.bovis_AF2122/97 -----------------YGLAYIPDGMELPNKVYLASADHAIPVDEIARC
Rv3879c|M.tuberculosis_H37Rv -----------------YGLAYIPDGMELPNKVYLASADHAIPVDEIARC
Mvan_2552|M.vanbaalenii_PYR-1 PIFGEAGVAAPPLPPAPGGAGAVPAGVVTPPVPGVPGGAGAVPAGAVTPP
Mflv_3843|M.gilvum_PYR-GCK PVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVPAGAVTPP
MLBr_01556|M.leprae_Br4923 ------------------QLNLILKGDNAGTVEALEEALMGIQVDDEVAL
MAB_3131c|M.abscessus_ATCC_199 ------------------QLNLILKGDNAGTVEALEEALLGIAIDDEVQL
MUL_1004|M.ulcerans_Agy99 ------------------QTAYVFTAVGTPGPAEVQRLPLNVTWVNLTTG
MSMEG_5700|M.smegmatis_MC2_155 ------------------LDPVLPAPAPAPAPAPAPGAPAAVAAPAPDPL
MMAR_5451|M.marinum_M ------------------GAGNLAERSGRSSPSSIADLLADPRLSHYNDV
TH_4426|M.thermoresistible__bu -----------------TAPIEHAAETSVPAEVEIPGAEIDHRAEVATPP
MAV_4827|M.avium_104 ----------------LLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQ
Mb3909c|M.bovis_AF2122/97 AT------------------------------------------------
Rv3879c|M.tuberculosis_H37Rv AT------------------------------------------------
Mvan_2552|M.vanbaalenii_PYR-1 TP----------------PVPGSSSGG-----------------------
Mflv_3843|M.gilvum_PYR-GCK APGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVPGGASTVP
MLBr_01556|M.leprae_Br4923 RV------------------------------------------------
MAB_3131c|M.abscessus_ATCC_199 RV------------------------------------------------
MUL_1004|M.ulcerans_Agy99 KS------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 AP------------------------------------------------
MMAR_5451|M.marinum_M RAHTS---------------------------------------------
TH_4426|M.thermoresistible__bu VD------------------------------------------------
MAV_4827|M.avium_104 SP------------------------------------------------
Mb3909c|M.bovis_AF2122/97 ---------------------YPVLAVQAWAAFHDMTLRAVIGTAEQLAS
Rv3879c|M.tuberculosis_H37Rv ---------------------YPVLAVQAWAAFHDMTLRAVIGTAEQLAS
Mvan_2552|M.vanbaalenii_PYR-1 ------------------FVNYPAPPVPPTPPNSAGVNTGTPGSPIPGTP
Mflv_3843|M.gilvum_PYR-GCK GNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPGSPAPGTP
MLBr_01556|M.leprae_Br4923 ----------------------IDRGVGGITETNVNLASASDAIIIGFNV
MAB_3131c|M.abscessus_ATCC_199 ----------------------IDRGVGGVTETNVNLASASDAIIIGFNV
MUL_1004|M.ulcerans_Agy99 ------------------------GSVTLKPRSDINPEGPTTLTGIADTG
MSMEG_5700|M.smegmatis_MC2_155 ---------------------APNADVAPTPPEGVPHLASPENLPPGTTE
MMAR_5451|M.marinum_M ---------------------VNAANLEILPTAEYTSAQRGLSGEDLRSA
TH_4426|M.thermoresistible__bu ---------------------GPPVEVENSVEVATPPHXXGPGAVVDXXX
MAV_4827|M.avium_104 ------------------------PQHQTPPGEGTPPKPDGPGNYGGGHV
Mb3909c|M.bovis_AF2122/97 SDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLL
Rv3879c|M.tuberculosis_H37Rv SDPGVAKIVLEPDDIPESGKMTGRSRLEVVDPSAAAQLADTTDQRLLDLL
Mvan_2552|M.vanbaalenii_PYR-1 GSTLTISDLLTPPGVARTVQNTASSVMSIAPPGTPPVPGGAGSVSVGVPA
Mflv_3843|M.gilvum_PYR-GCK GSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGSVSLAVPG
MLBr_01556|M.leprae_Br4923 RAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRA
MAB_3131c|M.abscessus_ATCC_199 RAEGKATELANREGVDIRYYSVIYQAIDEIESALKGMLKPVYEEVELGRA
MUL_1004|M.ulcerans_Agy99 SGSIMSTIFGQVTTKERQCQFMPTIGSTVVP-------------------
MSMEG_5700|M.smegmatis_MC2_155 TPDQIPGQGPNMTYLREIWHAIQTQDISGKDALLALTQRPLTTPDVPGGA
MMAR_5451|M.marinum_M VDTVSKFYNLVLADCGAGLFDPVTLGVLDTASAIVILTNVSIDSARQAAI
TH_4426|M.thermoresistible__bu XRRPGADPRPXPLPVAAQLHPRPVGCDGPRRPHRGGVVTASRQPRRLTGR
MAV_4827|M.avium_104 PTPGAGGSGGSGGGHVPTPGAGGSGGSGGGHVPTPGTGGPGGTGGSGGGH
Mb3909c|M.bovis_AF2122/97 PPAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEI
Rv3879c|M.tuberculosis_H37Rv PPAPVDVNPPGDERHMLWFELMKPMTSTATGREAAHLRAFRAYAAHSQEI
Mvan_2552|M.vanbaalenii_PYR-1 PPSPLTPLAATG-----LSNLVSPPSLTIPSIPGLPVPLPNEVPVPSDLL
Mflv_3843|M.gilvum_PYR-GCK TPSPIAPLAATG-----LSNLVSPPSLTIPSIPGLPVPLPNTVPVPSDLL
MLBr_01556|M.leprae_Br4923 EIRALFRSSKVG-------IIAGCIISSGVVRRNAKVRLLRDNIVVTDNL
MAB_3131c|M.abscessus_ATCC_199 EIRAMFRSSKVG-------NIAGCLVTSGIIRRNAKARLLRDNIVVAETV
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 APN----------------------------RPVAPPPAPGDPALAPAPA
MMAR_5451|M.marinum_M ALDWLRKHGYQDLASRACVAINHVAVGETNVSEQQLVRDFEQQLQPGRVV
TH_4426|M.thermoresistible__bu VDAPHLHRHRGQPGD-AQHQHGHHRRQRERGFHGDRATITHTLVFNARLM
MAV_4827|M.avium_104 VPTPGAGTPGGSGGG---HLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLG
Mb3909c|M.bovis_AF2122/97 ALHQAHTATDAAVQRVAVADWLYWQYVTGLLDRALAAAS---------
Rv3879c|M.tuberculosis_H37Rv ALHQAHTATDAAVQRVAVADWLYWQYVTGLLDRALAAAC---------
Mvan_2552|M.vanbaalenii_PYR-1 CVGTDWSATQGDSATTPVNAEIPRALVTGAAPVGDRRDRWDTR-----
Mflv_3843|M.gilvum_PYR-GCK CVGTDWSASQGDSAATPPAAEVPR-VVTGAAPTGDRRDRWGNR-----
MLBr_01556|M.leprae_Br4923 TVTSLRREKD-DVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA
MAB_3131c|M.abscessus_ATCC_199 TISSLRREKD-DVVEVRDGYECGLTLTYNDIKEGDVIEAYELREKERV
MUL_1004|M.ulcerans_Agy99 ------------------------------------------------
MSMEG_5700|M.smegmatis_MC2_155 PLGAPAPAPAPEPAPVGAPAPVGAPVPPPA------------------
MMAR_5451|M.marinum_M VLPWDRHIAAGTEIHLDQLGPVYRRRVLELAAALSDDFERAGRR----
TH_4426|M.thermoresistible__bu MLVSALTIESPVTTAYRMAPNAAAAIVPTAYSTVDIPASSTINIVVLA
MAV_4827|M.avium_104 GFGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK