For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDPAPSSASDPAWTELSEAEAVFTRVRPRLFGVAYRMTGTVAEAEDAVQEAWLRWQDTDRAAVTDPVPFL MTVVTRICLNVLQSARARHETYIGPWLPEPVDTTADPALGAERGAALELATLMLLERLAPPERAAYILRE AFDYPYEQIAETVGVSVPNARQLVSRARRRVTTRRAAPVATAEQDRLLRAFVTAARSGDLDALEEILAED VVSHTDGNGARNAAQIPVVGRTTVAKFVRAFRNRLWPGASLRWITANGHSAVLVVHDDSPAAFLTVAASA DGIHRLLWVLAPEKLAGIAQAQGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1692 | - | - | 100% (304) | ECF-family protein RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_5444 | - | 6e-47 | 36.30% (292) | RNA polymerase sigma-70 factor protein |
| M. smegmatis MC2 155 | MSMEG_6817 | - | 2e-45 | 38.60% (285) | RNA polymerase sigma factor, sigma-70 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 1e-41 | 38.05% (297) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_1927 | - | 4e-48 | 37.59% (282) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 1e-41 | 38.05% (297) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-08 | 26.70% (176) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_1126c | - | 6e-47 | 37.46% (283) | putative sigma factor |
| M. marinum M | MMAR_4487 | - | 8e-45 | 35.82% (282) | alternative RNA polymerase sigma factor |
| M. avium 104 | MAV_1129 | - | 7e-49 | 38.31% (295) | sigma factor |
| M. thermoresistible (build 8) | TH_1144 | - | 3e-46 | 39.72% (282) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 8e-32 | 34.49% (287) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_4999 | - | 8e-92 | 60.85% (281) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3361c|M.bovis_AF2122/97 ----------------------------MEVSEFEALRQHLMSVAYRLTG
Rv3328c|M.tuberculosis_H37Rv ----------------------------MEVSEFEALRQHLMSVAYRLTG
MUL_3630|M.ulcerans_Agy99 ------------------------MTDPALLARFQAARPRLGALAYRMLG
MSMEG_1692|M.smegmatis_MC2_155 MDPAPSSAS------DPAWT-----ELSEAEAVFTRVRPRLFGVAYRMTG
Mvan_4999|M.vanbaalenii_PYR-1 MSPARNTESCLTVGVSEARTGDADGDLADAVAAFTAVRPRIFGVAYRMLG
MMAR_4487|M.marinum_M --------------MTPPSH------SDEHAERFTLLRPLLFTIAYEILG
MAV_1129|M.avium_104 -------------MMTQAPT------GSEHADRFTLLRPLLFTIAYEMLG
Mflv_1927|M.gilvum_PYR-GCK --------------MTAAP-------GDEHAERFTQLRPLLFTIAYEILG
TH_1144|M.thermoresistible__bu ----------VTVGSAAGAA------DGEHAERFTLLRPLLFTIAYEILG
MAB_1126c|M.abscessus_ATCC_199 ------------------MS------GTDHAELFTHLRPLLFTIAYEMLG
MLBr_01076|M.leprae_Br4923 ---------------------------------------MGDGIGMEREG
:. . *
Mb3361c|M.bovis_AF2122/97 TVADAEDIVQEAWLRWDSQD------TVIADPRAWLTTVVSRLGLDKLRS
Rv3328c|M.tuberculosis_H37Rv TVADAEDIVQEAWLRWDSPD------TVIADPRAWLTTVVSRLGLDKLRS
MUL_3630|M.ulcerans_Agy99 SLADAEDVVQEAWLRLNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRD
MSMEG_1692|M.smegmatis_MC2_155 TVAEAEDAVQEAWLRWQDTD-----RAAVTDPVPFLMTVVTRICLNVLQS
Mvan_4999|M.vanbaalenii_PYR-1 SVAEAEDVLQEVWLRWQKCD-----RRAVRDPAAFLITATTRLSINERQS
MMAR_4487|M.marinum_M SATESDDVLQESYLRWAAVD-----LSAVRDTKSYLAQLVTRQSLNALRA
MAV_1129|M.avium_104 SATEADDVLQDSYLRWSTVD-----LATVRDTKSYLAQLVTRQALNALRA
Mflv_1927|M.gilvum_PYR-GCK SATESDDVLQESYLRWAEVD-----LATVTDTKAYLARLVTRQALNTLRA
TH_1144|M.thermoresistible__bu SATEADDVLQDGYLRWSQVD-----LGTVRDTKAFLAQLITREALKVLRT
MAB_1126c|M.abscessus_ATCC_199 SATEADDVLQESYLRWAQVD-----LDTVTDTKAYLAQIVSRQALNTLRT
MLBr_01076|M.leprae_Br4923 RWTGNTQCPLRVVPGDESPT-----LDGRASPEDLIITNLLSPTIMS-HP
: : . : : :
Mb3361c|M.bovis_AF2122/97 AAHRRETYTGTWLPEPVVTG--LDATDPLAAVVAAEDARFAAMVVLERLR
Rv3328c|M.tuberculosis_H37Rv AAHRRETYTGTWLPEPVVTG--LDATDPLAAVVAAEDARFAAMVVLERLR
MUL_3630|M.ulcerans_Agy99 RRGRGREELVGQLPDPIVDG--VAAFDPEHHAMLADAVGLALFVVLDTLA
MSMEG_1692|M.smegmatis_MC2_155 ARARHETYIGPWLPEPVDTT-----ADPALGAERGAALELATLMLLERLA
Mvan_4999|M.vanbaalenii_PYR-1 ARARRETYIGPWLPDPVDTG-----ADPTLGAERAEALEFATLMLMERLT
MMAR_4487|M.marinum_M GARRREEYVGPWLPEPLLLD----ESDPSADLVLAESVSMAMLVLLETLT
MAV_1129|M.avium_104 GARRREEYVGPWLPEPLLLD----EQDPSTDVVLAESISMAMLVLLETLS
Mflv_1927|M.gilvum_PYR-GCK QSRRREDYVGPWLPEPLLT-----EADPSADVVLAESVSMAMLVVLETLS
TH_1144|M.thermoresistible__bu RSRRREDYVGPWLPEPLLLE----DHDPESDVVLAESVSMAMLVLLETLS
MAB_1126c|M.abscessus_ATCC_199 NSRRREEYVGPWLPEPVRVAYDDSDKDASTDVVLAESVSMAMLVVLETLA
MLBr_01076|M.leprae_Br4923 PPSRDDDWVEPFD-------------ALQGTAVFDATGDKATMPSWEELV
* * : : *
Mb3361c|M.bovis_AF2122/97 PDQRVAFVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALIS
Rv3328c|M.tuberculosis_H37Rv PDQRVAFVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALIS
MUL_3630|M.ulcerans_Agy99 PAERLAFVLHDVFAVPFDQIAPILERTPEATRKLASRARRRIERAEPFPD
MSMEG_1692|M.smegmatis_MC2_155 PPERAAYILREAFDYPYEQIAETVGVSVPNARQLVSRARRRVTTRRAAPV
Mvan_4999|M.vanbaalenii_PYR-1 PAERAAYVLREAFDYPYGLIAETIETSQANARQLVSRARRHLAEARRHDV
MMAR_4487|M.marinum_M PDERAVFVLREVFGFDYDEIADAVGKPAPTVRQVAHRARAHIQARRKKYG
MAV_1129|M.avium_104 PDERAVFVLREVFGFDYDEIAEAVGKPAPTVRQVARRAREHVRARRKRHP
Mflv_1927|M.gilvum_PYR-GCK PDERAVFVLREVFGFGHDEIAATLGKSTAAVRQIAHRAREHVQSRRKRFE
TH_1144|M.thermoresistible__bu PDERAVFVLREVFDFDYDEIAGAVGKSVPAVRQVAHRSREHVRARRKRFD
MAB_1126c|M.abscessus_ATCC_199 PDERAVFVMREVFGFDYSEIASTVGKSEVAVRQMAHRARAHVQSRRRRFT
MLBr_01076|M.leprae_Br4923 R-QHAARVYWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLH
:: . : : * . .
Mb3361c|M.bovis_AF2122/97 GDP----DPAHNEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPT
Rv3328c|M.tuberculosis_H37Rv GDP----DPAHNEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPT
MUL_3630|M.ulcerans_Agy99 RD-----LCAQREVVDAFFAAGRSGNFERLVSVLHPDVVLRGDFGPNTPR
MSMEG_1692|M.smegmatis_MC2_155 A------TAEQDRLLRAFVTAARSGDLDALEEILAEDVVSHTDGNGARNA
Mvan_4999|M.vanbaalenii_PYR-1 D------PAEQRQLLTAFVAAAQNGDMATLESLFAEDIVSYTDGNGIRNA
MMAR_4487|M.marinum_M ----DVDPQRNAQLTAQFLQTAASGDVEALMAMLAPDATWLADSGGKVSA
MAV_1129|M.avium_104 GAGQAIDPKRNAELTAQFLATAASGDVEALMAMLAPDATWTADSGGVVSA
Mflv_1927|M.gilvum_PYR-GCK P----VDPKTSGEITMTFFAAAATGDLDALMAMLAPDVVWTADSDGKVSA
TH_1144|M.thermoresistible__bu P----VPAAQTTELAEEFIHAATTGDLDRLLSLLAPGATFTTDHGGKAPA
MAB_1126c|M.abscessus_ATCC_199 P-----TDRQAEELTTKFLLAAAGGDVDALVEMLAPDAVWTSDGGGKVSA
MLBr_01076|M.leprae_Br4923 R--------ITTNLFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHD
.: :. . : . :
Mb3361c|M.bovis_AF2122/97 AVRAVRGSDKVVRFILGLVQRYGPGLFGANQLALVNGELGAYTAGLPGVD
Rv3328c|M.tuberculosis_H37Rv AVRAVRGSDKVVRFILGLVQRYGPGLFGANQLALVNGELGAYTAGLPGVD
MUL_3630|M.ulcerans_Agy99 FR--AQGAATVAKLARSYAGPERTVLN-----TLVNGAAGAVIS------
MSMEG_1692|M.smegmatis_MC2_155 AQIPVVGRTTVAKFVRAFRNRLWP--GASLRWITANGHSAVLVVHDDSP-
Mvan_4999|M.vanbaalenii_PYR-1 ARHPVVGRETVARFVCAFRRRVFA--DAVLTWVTVNSAPAVVISHGGGPF
MMAR_4487|M.marinum_M ARKPVVGAERVARAITGLIRKAAT--ELQVELVTCNSAPAVLFYLGGQL-
MAV_1129|M.avium_104 ARRPVVGAEKVARAITGLFRKAAEYATLRVDTVTCNGAPAVLLYLGDRL-
Mflv_1927|M.gilvum_PYR-GCK ARRPVEGADKVARLILGFVRLAGG--EARVEPAFYNSAPALVLYTGDVL-
TH_1144|M.thermoresistible__bu VARPVEGAKKVANLVMGFFRNRHRVPDLRLEATNCNHAPAVLVYTGDHL-
MAB_1126c|M.abscessus_ATCC_199 ARRPVYGADRVARVAIGLSRAAAEFPDVRMEFSTFNSTPALLIYTEGRL-
MLBr_01076|M.leprae_Br4923 SRLGPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLG------
: . .
Mb3361c|M.bovis_AF2122/97 GYRAMAPRITAITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHH
Rv3328c|M.tuberculosis_H37Rv GYRAMAPRITAITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHH
MUL_3630|M.ulcerans_Agy99 -ISEQASAVMRFLVRNGRIAAIDVLADPQRIATLDISG-LSGPGG-----
MSMEG_1692|M.smegmatis_MC2_155 ------AAFLTVAASADGIHRLLWVLAPEKLAGIAQAQGR----------
Mvan_4999|M.vanbaalenii_PYR-1 HDGGVFETFVALTPSERGITQLLWHRLEGKVSHLG---------------
MMAR_4487|M.marinum_M ------EGVITLEIVGDKITNFYVMRNPDKLTAVARAHEISRG-------
MAV_1129|M.avium_104 ------EGVITVEIAADKITNFYVMRNPHKLAALATARDVSRG-------
Mflv_1927|M.gilvum_PYR-GCK ------EGVVTFEVADGRITNFYAMRNPEKLTGVMVARTISR--------
TH_1144|M.thermoresistible__bu ------EAVVLLEIVDGAITNLYATRNPDKLAAVAAPRTITR--------
MAB_1126c|M.abscessus_ATCC_199 ------DVVLAVSIEDGKVEHIFAIRNPDKLATAEITRHISR--------
MLBr_01076|M.leprae_Br4923 ------TVRSRIHRGRQALRDYLLTAHPRDGATTDATHVKSA--------
. : :
Mb3361c|M.bovis_AF2122/97 RN
Rv3328c|M.tuberculosis_H37Rv RN
MUL_3630|M.ulcerans_Agy99 --
MSMEG_1692|M.smegmatis_MC2_155 --
Mvan_4999|M.vanbaalenii_PYR-1 --
MMAR_4487|M.marinum_M --
MAV_1129|M.avium_104 --
Mflv_1927|M.gilvum_PYR-GCK --
TH_1144|M.thermoresistible__bu --
MAB_1126c|M.abscessus_ATCC_199 --
MLBr_01076|M.leprae_Br4923 --