For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSLATTWSKAMGIDVPIVNAPMGGAAGARLAAAVSEAGGLGMVGMGSSATPEQLRRELADLAKPSRPFGI GLVHWVMTERPDLFDIALEARPALLSVSFGDDWAWVRRAHDVGVTVATQVATVGDALRAAEAGVDVLVAR GAEAGGHGRPALGTLPLLTQVLDAVELPVLAAGGVASPRGLAAVLAAGAAAAWLGTVFTTCVEASTPAAA RDRLLAANGENTMLTSEFDIRAGYRWPADVPERVLTDENGAATPVNAGQGVGMVNQSLTVAETMSRLCWG AEALLRRWS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1660 | - | - | 100% (289) | oxidoreductase, 2-nitropropane dioxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_6004 | - | 4e-27 | 34.02% (241) | oxidoreductase, 2-nitropropane dioxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_4971 | - | 5e-23 | 29.46% (336) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0021c | - | 1e-46 | 37.62% (319) | hypothetical protein Mb0021c |
| M. gilvum PYR-GCK | Mflv_5156 | - | 7e-89 | 55.31% (311) | 2-nitropropane dioxygenase, NPD |
| M. tuberculosis H37Rv | Rv0021c | - | 1e-46 | 37.62% (319) | hypothetical protein Rv0021c |
| M. leprae Br4923 | MLBr_00387 | guaB2 | 8e-05 | 33.90% (118) | inosine 5'-monophosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0159 | - | 1e-39 | 39.76% (249) | 2-nitropropane dioxygenase |
| M. marinum M | MMAR_2084 | - | 2e-79 | 51.90% (316) | hypothetical protein MMAR_2084 |
| M. avium 104 | MAV_3496 | - | 2e-79 | 53.50% (314) | oxidoreductase, 2-nitropropane dioxygenase family protein |
| M. thermoresistible (build 8) | TH_1976 | - | 1e-99 | 67.27% (278) | oxidoreductase, 2-nitropropane dioxygenase family protein |
| M. ulcerans Agy99 | MUL_1961 | - | 2e-45 | 36.02% (322) | hypothetical protein MUL_1961 |
| M. vanbaalenii PYR-1 | Mvan_4537 | - | 4e-86 | 54.10% (305) | 2-nitropropane dioxygenase, NPD |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0021c|M.bovis_AF2122/97 --------------------------------------------------
Rv0021c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0159|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1961|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_1660|M.smegmatis_MC2_155 --------------------------------------------------
TH_1976|M.thermoresistible__bu --------------------------------------------------
Mflv_5156|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4537|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2084|M.marinum_M --------------------------------------------------
MAV_3496|M.avium_104 --------------------------------------------------
MLBr_00387|M.leprae_Br4923 MIRGMSNLKESSDFVASSYVRLGGLMDDPAATGGDNPHKVAMLGLTFDDV
Mb0021c|M.bovis_AF2122/97 -------------MVLSTAFSQMFGIDYPIVSAPMDLIAGGELAAAVSGA
Rv0021c|M.tuberculosis_H37Rv -------------MVLSTAFSQMFGIDYPIVSAPMDLIAGGELAAAVSGA
MAB_0159|M.abscessus_ATCC_1997 -------------MTFNTRLTDRFGIEHPVVLAPMDDVADARLASAVSAA
MUL_1961|M.ulcerans_Agy99 -------------MSLNTRLTEFLGVQHPILLAPMAMTSGGRLAAAVTAA
MSMEG_1660|M.smegmatis_MC2_155 -------------MSLATTWSKAMGIDVPIVNAPMGGAAGARLAAAVSEA
TH_1976|M.thermoresistible__bu -----------------------MGIEVPIVNAPMGGTAGAELAAAVSAA
Mflv_5156|M.gilvum_PYR-GCK ------------MDTLSTPWSAELGLDVPIVNAPMGGAAGGTLAAAVSRA
Mvan_4537|M.vanbaalenii_PYR-1 ------------MKATSTQWSQAMGLAAPIVNAPMGGVAGGALAAAVSRA
MMAR_2084|M.marinum_M --------------MLATGWSRGFGLRVPIVNAPMGGVAGGRLAAAVTAA
MAV_3496|M.avium_104 --------------MLSTPWSAGFGLRVPIVNAPMGGVAGGRLAAAVTAA
MLBr_00387|M.leprae_Br4923 LLLPAASDVVPATADISSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARA
: : *:: :.* : . :* *:: *
Mb0021c|M.bovis_AF2122/97 GGLGLIGGG---YGDRDWLARQFDLAAG---APVGCG-------------
Rv0021c|M.tuberculosis_H37Rv GGLGLIGGG---YGDRDWLARQFDLAAG---APVGCG-------------
MAB_0159|M.abscessus_ATCC_1997 GGLGLLGGG---YADADWVRQQFDQVS----AAVGCG-------------
MUL_1961|M.ulcerans_Agy99 GGLGLIGGG---YGEAEWLQRQLEQAQG---QRVGCG-------------
MSMEG_1660|M.smegmatis_MC2_155 GGLGMVGMGS--SATPEQLRRELADLAKPS-RPFGIG-------------
TH_1976|M.thermoresistible__bu GGLGMIGMGS--SATAAVLRRELAGPIT---RPFGIG-------------
Mflv_5156|M.gilvum_PYR-GCK GGLGMVGMGS--SASAAQLRAQLAELGELK-RPFGIG-------------
Mvan_4537|M.vanbaalenii_PYR-1 GGLGMIGIGS--AGSADRLHTELRHVSDLVDRPFGIG-------------
MMAR_2084|M.marinum_M GGLGMIGMGS--RATRAALAEQLRQVSG----RFGIG-------------
MAV_3496|M.avium_104 GGLGMVGMGS--VATRRLLAEQLQYVDG----RFGIG-------------
MLBr_00387|M.leprae_Br4923 GGMGVLHRNLPVGEQAGQVETVKRSEAGMVTDPVTCRPDNTLAQVGALCA
**:*:: . : .
Mb0021c|M.bovis_AF2122/97 ---------------------------------FITWSLARQPQLLDLAL
Rv0021c|M.tuberculosis_H37Rv ---------------------------------FITWSLARQPQLLDLAL
MAB_0159|M.abscessus_ATCC_1997 ---------------------------------FITWTLKGNEHVLEHAL
MUL_1961|M.ulcerans_Agy99 ---------------------------------FITWSLARNPELLDLIL
MSMEG_1660|M.smegmatis_MC2_155 ---------------------------------LVHWVMTERPDLFDIAL
TH_1976|M.thermoresistible__bu ---------------------------------LVQWVVDAEPELLDVAL
Mflv_5156|M.gilvum_PYR-GCK ---------------------------------VIDWVIRKEPELLTTAL
Mvan_4537|M.vanbaalenii_PYR-1 ---------------------------------LISWAVAEQPRLLEAAL
MMAR_2084|M.marinum_M ---------------------------------LVDWVMRSEAGLLEDAL
MAV_3496|M.avium_104 ---------------------------------LVDWVMRNEAGLLEDAL
MLBr_00387|M.leprae_Br4923 RFRISGLPVVDDSGALAGIITNRDMRFEVDQSKQVAEVMTKTPLITAAEG
: : :
Mb0021c|M.bovis_AF2122/97 QYEPVAVMLSFGDPAVFADAIKSAG-----TRLVCQIQNRTQAERALQVG
Rv0021c|M.tuberculosis_H37Rv QYEPVAVMLSFGDPAVFADAIKSAG-----TRLVCQIQNRTQAERALQVG
MAB_0159|M.abscessus_ATCC_1997 ARGPAALFLSFGDPAPYAPRIRAAG-----VPLICQVHNIRQAARAIEVG
MUL_1961|M.ulcerans_Agy99 AANPAAIMLSFGDPHNFAGPIHDAG-----IPLICQIHTREQALRVLEVG
MSMEG_1660|M.smegmatis_MC2_155 EARPALLSVSFGDDWAWVRRAHDVG-----VTVATQVATVGDALRAAEAG
TH_1976|M.thermoresistible__bu AARPTLLSVSFGADYGWVERAHAEG-----ISAAAQVADVESGVRAQDAG
Mflv_5156|M.gilvum_PYR-GCK DARPTALSVSFGTEWDWVARARDAG-----CVSVTQVADVEAALRAVDAG
Mvan_4537|M.vanbaalenii_PYR-1 AARPALLSVSFGDDWAWVRRAHDAG-----CVTATQVADVDGAQRAADAG
MMAR_2084|M.marinum_M AAGPALLSVSFGTDWSWVGPARDAG-----IPTVTQVYDALGARRAADAG
MAV_3496|M.avium_104 AARPALLSVSFGTDWSWVAKAHDAG-----IPTVTQVYDSLGARQAVDAG
MLBr_00387|M.leprae_Br4923 VSADAALGLLRRNKIEKLPVVDGHGRLTGLITVKDFVKTEQHPLATKDND
. : : * : . : .
Mb0021c|M.bovis_AF2122/97 ADVLVAQGTEAGGHGHGPRSTLT-----------------LVPEIVDLVT
Rv0021c|M.tuberculosis_H37Rv ADVLVAQGTEAGGHGHGPRSTLT-----------------LVPEIVDLVT
MAB_0159|M.abscessus_ATCC_1997 ADVIVAQGGEAGGHGEGRRSTFT-----------------LVPEVVDLVA
MUL_1961|M.ulcerans_Agy99 PDIIVAQGSESGGHGMSVRSTFT-----------------LVPDVVDLVA
MSMEG_1660|M.smegmatis_MC2_155 VDVLVARGAEAGGHGRPALGTLP-----------------LLTQVLDAVE
TH_1976|M.thermoresistible__bu VDVVVARGAEGGGHGEPRLGTLP-----------------LLTELLDRLT
Mflv_5156|M.gilvum_PYR-GCK VQVLVARGAEAGGHGTPAVATLP-----------------LLAAILDRVE
Mvan_4537|M.vanbaalenii_PYR-1 VDVLVTRGAEAGGHGQPRVGTLP-----------------LLVEVLDRVA
MMAR_2084|M.marinum_M VDIVVARGAEGGGHGEVRLGTLP-----------------LLDAVLAAVS
MAV_3496|M.avium_104 VDILVARGSEGGGHGEVKLGLLP-----------------LLDAVLDAVS
MLBr_00387|M.leprae_Br4923 GRLLVGAAVGVGGDAWVRAMMLVDAGVDVLIVDTAHAHNRLVLDMVGKLK
::* . **.. : *: :: :
Mb0021c|M.bovis_AF2122/97 ARGTDIPVIAAGGIADGRGLAAALMLGAAGVLVGT---------------
Rv0021c|M.tuberculosis_H37Rv ARGTDIPVIAAGGIADGRGLAAALMLGAAGVLVGT---------------
MAB_0159|M.abscessus_ATCC_1997 GTAPQILVLAAGGVTDGRGLAASLALGADGVLVGT---------------
MUL_1961|M.ulcerans_Agy99 QRSAETLVVAAGGIADGRGLAAALALGADGALVGT---------------
MSMEG_1660|M.smegmatis_MC2_155 -----LPVLAAGGVASPRGLAAVLAAGAAAAWLGT---------------
TH_1976|M.thermoresistible__bu -----VPVLAAGGITSGRGLAAVLAAGAAGAWLGT---------------
Mflv_5156|M.gilvum_PYR-GCK -----VPVLAAGGIASGRALAAVLAAGAAGAWIGT---------------
Mvan_4537|M.vanbaalenii_PYR-1 -----VPVLAAGGIASGRGLAAALAAGASGGWLGT---------------
MMAR_2084|M.marinum_M -----VPVLAGGGIASPRSLAAVLAAGAAGAWVGT---------------
MAV_3496|M.avium_104 -----VPVLAGGGVASARSLAAVLAAGASGAWVGT---------------
MLBr_00387|M.leprae_Br4923 VEIGDRVQVIGGNVATRSAAAALVEAGADAVKVGVGPGSTCTTRVVAGVG
: .*.:: . ** : ** . :*.
Mb0021c|M.bovis_AF2122/97 --RFYATVEALSTPQARDPLLAATG-------------DDMCRTTIYDQL
Rv0021c|M.tuberculosis_H37Rv --RFYATVEALSTPQARDPLLAATG-------------DDMCRTTIYDQL
MAB_0159|M.abscessus_ATCC_1997 --RFWAAGEAAISRAAQRHALQVGG-------------DDTIRQHVYDIV
MUL_1961|M.ulcerans_Agy99 --RFWACPEALVSPRAHQRAVEASG-------------DDTIRTRVYDIV
MSMEG_1660|M.smegmatis_MC2_155 --VFTTCVEASTPAAARDRLLAANG-------------ENTMLTSEFDIR
TH_1976|M.thermoresistible__bu --VFTACAEALTAPDARAALLAAPS-------------TATTTTREFDIA
Mflv_5156|M.gilvum_PYR-GCK --AFATCPESLFPDEARRALLTADA-------------TDTLTTRVFDVA
Mvan_4537|M.vanbaalenii_PYR-1 --AFAACPESTLPDAAAEVMLAARN-------------TDTVTTRVFDIA
MMAR_2084|M.marinum_M --RLAACPEALTGEPSRQALIAARE-------------TDTSTTRVFDVA
MAV_3496|M.avium_104 --RLSACPEALTADGNRRALVEAAE-------------TDTAVTRAFDVA
MLBr_00387|M.leprae_Br4923 APQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTTMLGSLL
: : *: : . .
Mb0021c|M.bovis_AF2122/97 RRYPWPQGHTMSVLSNALTDQFEDTELDILHR-EEAMARYWRAVPARDYS
Rv0021c|M.tuberculosis_H37Rv RRYPWPQGHTMSVLSNALTDQFEDTELDILHR-EEAMARYWRAVAARDYS
MAB_0159|M.abscessus_ATCC_1997 RGKRWPSAYSGRVLRNDFVDKWHRREAELAQHLDQARSEYQSGVAAEDYR
MUL_1961|M.ulcerans_Agy99 RQRDWPAEYDLRLLSNSLIQAWHGNESELIRRLPDLLGAFENAVAAEDFE
MSMEG_1660|M.smegmatis_MC2_155 AGYRWPADVPERVLT------------------------------DENGA
TH_1976|M.thermoresistible__bu AGYRWPATIPERVLT------------------------------DPAGD
Mflv_5156|M.gilvum_PYR-GCK LGYPWPAHFPERVLRNAFTAAWDGR----TPD-DDARARLAEAIADDDFR
Mvan_4537|M.vanbaalenii_PYR-1 LGYPWPPTIPERVLRNAFTDSWHGRESELAAD-TEAVTELRAAIAADDYR
MMAR_2084|M.marinum_M DGLPWPQRFPSRVLTNDFVARWNGNETALAAD-ADARAELAAASAAEDLR
MAV_3496|M.avium_104 KGLPWPARFPSRVLANDFVERWTGREETL--D-AGACEELAAAIAAGDCR
MLBr_00387|M.leprae_Br4923 AGTAEAPGELIFVNGKQFKSYRGMGSLGAMQGRGGDKSYSKDRYFADDAL
. :
Mb0021c|M.bovis_AF2122/97 IANVTAGQAAG-LVNAVLPAADVITGMAQQAARTLTAMRAV---------
Rv0021c|M.tuberculosis_H37Rv IANVTAGQAAG-LVNAVLPAADVITGMAQQAARTLTAMRAV---------
MAB_0159|M.abscessus_ATCC_1997 TANLIVGEGIG-QVRSVESVADIIESMVAQAAAINSTSRS----------
MUL_1961|M.ulcerans_Agy99 MATVLVGEAVG-LISRVGPAADIVSEMVCDATRILNRSG-----------
MSMEG_1660|M.smegmatis_MC2_155 ATPVNAGQGVG-MVNQSLTVAETMSRLCWGAEALLRRWS-----------
TH_1976|M.thermoresistible__bu PTPVNAGQGVG-MVTAAQPAAAVIERLCSRAEQLLTRWGG----------
Mflv_5156|M.gilvum_PYR-GCK VAPVNAGQGVD-DITAVEPAAMVIARLCDDARRLLAKPPTR---------
Mvan_4537|M.vanbaalenii_PYR-1 LAPVNVGQGVS-ELTAIEPAARVIQRLCDEAREVGQQ-------------
MMAR_2084|M.marinum_M VAPVDAGQGVG-MIPDGAPAGEVIEQMCSGARELLARWA-----------
MAV_3496|M.avium_104 VAPVDAGQGVG-MIRNDATVAEVIDEMCSGAEQLLSRWGS----------
MLBr_00387|M.leprae_Br4923 SEDKLVPEGIEGRVPFRGPLSSVIHQLVGGLRAAMGYTGSPTIEVLQQAQ
. :. : . . : :
Mb0021c|M.bovis_AF2122/97 -----------------------------
Rv0021c|M.tuberculosis_H37Rv -----------------------------
MAB_0159|M.abscessus_ATCC_1997 -----------------------------
MUL_1961|M.ulcerans_Agy99 -----------------------------
MSMEG_1660|M.smegmatis_MC2_155 -----------------------------
TH_1976|M.thermoresistible__bu -----------------------------
Mflv_5156|M.gilvum_PYR-GCK -----------------------------
Mvan_4537|M.vanbaalenii_PYR-1 -----------------------------
MMAR_2084|M.marinum_M -----------------------------
MAV_3496|M.avium_104 -----------------------------
MLBr_00387|M.leprae_Br4923 FVRITPAGLKESHPHDVAMTVEAPNYYPR