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M. thermoresistible (build 8) TH_1976 (-)

annotation: oxidoreductase, 2-nitropropane dioxygenase family protein
coordinates: 3829017 - 3829853
length: 279

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1976--100% (279)oxidoreductase, 2-nitropropane dioxygenase family protein
M. thermoresistible (build 8)TH_1758-3e-2236.41% (206) POSSIBLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_4620-5e-2233.76% (237) PUTATIVE 2-nitropropane dioxygenase, NPD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0021c-4e-4639.09% (307) hypothetical protein Mb0021c
M. gilvum PYR-GCKMflv_5156-7e-9158.94% (302) 2-nitropropane dioxygenase, NPD
M. tuberculosis H37RvRv0021c-9e-4638.44% (307) hypothetical protein Rv0021c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0159-1e-4136.63% (303) 2-nitropropane dioxygenase
M. marinum MMMAR_2084-1e-8256.25% (304) hypothetical protein MMAR_2084
M. avium 104MAV_3496-7e-8255.12% (303) oxidoreductase, 2-nitropropane dioxygenase family protein
M. smegmatis MC2 155MSMEG_1660-2e-9967.27% (278) oxidoreductase, 2-nitropropane dioxygenase family protein
M. ulcerans Agy99MUL_1961-8e-4535.90% (312) hypothetical protein MUL_1961
M. vanbaalenii PYR-1Mvan_4537-6e-8958.03% (305) 2-nitropropane dioxygenase, NPD

CLUSTAL 2.0.9 multiple sequence alignment


TH_1976|M.thermoresistible__bu      -----------MGIEVPIVNAPMGGTAGAELAAAVSAAGGLGMIGMGSSA
MSMEG_1660|M.smegmatis_MC2_155      -MSLATTWSKAMGIDVPIVNAPMGGAAGARLAAAVSEAGGLGMVGMGSSA
Mflv_5156|M.gilvum_PYR-GCK          MDTLSTPWSAELGLDVPIVNAPMGGAAGGTLAAAVSRAGGLGMVGMGSSA
Mvan_4537|M.vanbaalenii_PYR-1       MKATSTQWSQAMGLAAPIVNAPMGGVAGGALAAAVSRAGGLGMIGIGSAG
MMAR_2084|M.marinum_M               --MLATGWSRGFGLRVPIVNAPMGGVAGGRLAAAVTAAGGLGMIGMGSRA
MAV_3496|M.avium_104                --MLSTPWSAGFGLRVPIVNAPMGGVAGGRLAAAVTAAGGLGMVGMGSVA
Mb0021c|M.bovis_AF2122/97           -MVLSTAFSQMFGIDYPIVSAPMDLIAGGELAAAVSGAGGLGLIGGG-YG
Rv0021c|M.tuberculosis_H37Rv        -MVLSTAFSQMFGIDYPIVSAPMDLIAGGELAAAVSGAGGLGLIGGG-YG
MAB_0159|M.abscessus_ATCC_1997      -MTFNTRLTDRFGIEHPVVLAPMDDVADARLASAVSAAGGLGLLGGG-YA
MUL_1961|M.ulcerans_Agy99           -MSLNTRLTEFLGVQHPILLAPMAMTSGGRLAAAVTAAGGLGLIGGG-YG
                                               :*:  *:: ***   :.. **:**: *****::* *  .

TH_1976|M.thermoresistible__bu      TAAVLRRELAGPIT---RPFGIGLVQWVVDAEPELLDVALAARPTLLSVS
MSMEG_1660|M.smegmatis_MC2_155      TPEQLRRELADLAKPS-RPFGIGLVHWVMTERPDLFDIALEARPALLSVS
Mflv_5156|M.gilvum_PYR-GCK          SAAQLRAQLAELGELK-RPFGIGVIDWVIRKEPELLTTALDARPTALSVS
Mvan_4537|M.vanbaalenii_PYR-1       SADRLHTELRHVSDLVDRPFGIGLISWAVAEQPRLLEAALAARPALLSVS
MMAR_2084|M.marinum_M               TRAALAEQLRQVSG----RFGIGLVDWVMRSEAGLLEDALAAGPALLSVS
MAV_3496|M.avium_104                TRRLLAEQLQYVDG----RFGIGLVDWVMRNEAGLLEDALAARPALLSVS
Mb0021c|M.bovis_AF2122/97           DRDWLARQFDLAAG---APVGCGFITWSLARQPQLLDLALQYEPVAVMLS
Rv0021c|M.tuberculosis_H37Rv        DRDWLARQFDLAAG---APVGCGFITWSLARQPQLLDLALQYEPVAVMLS
MAB_0159|M.abscessus_ATCC_1997      DADWVRQQFDQVS----AAVGCGFITWTLKGNEHVLEHALARGPAALFLS
MUL_1961|M.ulcerans_Agy99           EAEWLQRQLEQAQG---QRVGCGFITWSLARNPELLDLILAANPAAIMLS
                                        :  ::          .* *.: * :  .  ::   *   *. : :*

TH_1976|M.thermoresistible__bu      FGADYGWVERAHAEGISAAAQVADVESGVRAQDAGVDVVVARGAEGGGHG
MSMEG_1660|M.smegmatis_MC2_155      FGDDWAWVRRAHDVGVTVATQVATVGDALRAAEAGVDVLVARGAEAGGHG
Mflv_5156|M.gilvum_PYR-GCK          FGTEWDWVARARDAGCVSVTQVADVEAALRAVDAGVQVLVARGAEAGGHG
Mvan_4537|M.vanbaalenii_PYR-1       FGDDWAWVRRAHDAGCVTATQVADVDGAQRAADAGVDVLVTRGAEAGGHG
MMAR_2084|M.marinum_M               FGTDWSWVGPARDAGIPTVTQVYDALGARRAADAGVDIVVARGAEGGGHG
MAV_3496|M.avium_104                FGTDWSWVAKAHDAGIPTVTQVYDSLGARQAVDAGVDILVARGSEGGGHG
Mb0021c|M.bovis_AF2122/97           FGDPAVFADAIKSAGTRLVCQIQNRTQAERALQVGADVLVAQGTEAGGHG
Rv0021c|M.tuberculosis_H37Rv        FGDPAVFADAIKSAGTRLVCQIQNRTQAERALQVGADVLVAQGTEAGGHG
MAB_0159|M.abscessus_ATCC_1997      FGDPAPYAPRIRAAGVPLICQVHNIRQAARAIEVGADVIVAQGGEAGGHG
MUL_1961|M.ulcerans_Agy99           FGDPHNFAGPIHDAGIPLICQIHTREQALRVLEVGPDIIVAQGSESGGHG
                                    **    :.   :  *     *:     . :. :.* :::*::* *.****

TH_1976|M.thermoresistible__bu      EPRLGTLPLLTELLDRLT-----VPVLAAGGITSGRGLAAVLAAGAAGAW
MSMEG_1660|M.smegmatis_MC2_155      RPALGTLPLLTQVLDAVE-----LPVLAAGGVASPRGLAAVLAAGAAAAW
Mflv_5156|M.gilvum_PYR-GCK          TPAVATLPLLAAILDRVE-----VPVLAAGGIASGRALAAVLAAGAAGAW
Mvan_4537|M.vanbaalenii_PYR-1       QPRVGTLPLLVEVLDRVA-----VPVLAAGGIASGRGLAAALAAGASGGW
MMAR_2084|M.marinum_M               EVRLGTLPLLDAVLAAVS-----VPVLAGGGIASPRSLAAVLAAGAAGAW
MAV_3496|M.avium_104                EVKLGLLPLLDAVLDAVS-----VPVLAGGGVASARSLAAVLAAGASGAW
Mb0021c|M.bovis_AF2122/97           HGPRSTLTLVPEIVDLVTARGTDIPVIAAGGIADGRGLAAALMLGAAGVL
Rv0021c|M.tuberculosis_H37Rv        HGPRSTLTLVPEIVDLVTARGTDIPVIAAGGIADGRGLAAALMLGAAGVL
MAB_0159|M.abscessus_ATCC_1997      EGRRSTFTLVPEVVDLVAGTAPQILVLAAGGVTDGRGLAASLALGADGVL
MUL_1961|M.ulcerans_Agy99           MSVRSTFTLVPDVVDLVAQRSAETLVVAAGGIADGRGLAAALALGADGAL
                                        . :.*:  ::  :        *:*.**::. *.*** *  ** .  

TH_1976|M.thermoresistible__bu      LGTVFTACAEALTAPDARAALLAAPSTATTTTREFDIAAGYRWPATIPER
MSMEG_1660|M.smegmatis_MC2_155      LGTVFTTCVEASTPAAARDRLLAANGENTMLTSEFDIRAGYRWPADVPER
Mflv_5156|M.gilvum_PYR-GCK          IGTAFATCPESLFPDEARRALLTADATDTLTTRVFDVALGYPWPAHFPER
Mvan_4537|M.vanbaalenii_PYR-1       LGTAFAACPESTLPDAAAEVMLAARNTDTVTTRVFDIALGYPWPPTIPER
MMAR_2084|M.marinum_M               VGTRLAACPEALTGEPSRQALIAARETDTSTTRVFDVADGLPWPQRFPSR
MAV_3496|M.avium_104                VGTRLSACPEALTADGNRRALVEAAETDTAVTRAFDVAKGLPWPARFPSR
Mb0021c|M.bovis_AF2122/97           VGTRFYATVEALSTPQARDPLLAATGDDMCRTTIYDQLRRYPWPQGHTMS
Rv0021c|M.tuberculosis_H37Rv        VGTRFYATVEALSTPQARDPLLAATGDDMCRTTIYDQLRRYPWPQGHTMS
MAB_0159|M.abscessus_ATCC_1997      VGTRFWAAGEAAISRAAQRHALQVGGDDTIRQHVYDIVRGKRWPSAYSGR
MUL_1961|M.ulcerans_Agy99           VGTRFWACPEALVSPRAHQRAVEASGDDTIRTRVYDIVRQRDWPAEYDLR
                                    :** : :  *:          : .          :*      **      

TH_1976|M.thermoresistible__bu      VLT------------------------------DPAGDPTPVNAGQGVGM
MSMEG_1660|M.smegmatis_MC2_155      VLT------------------------------DENGAATPVNAGQGVGM
Mflv_5156|M.gilvum_PYR-GCK          VLRNAFTAAWDGR----TPD-DDARARLAEAIADDDFRVAPVNAGQGVDD
Mvan_4537|M.vanbaalenii_PYR-1       VLRNAFTDSWHGRESELAAD-TEAVTELRAAIAADDYRLAPVNVGQGVSE
MMAR_2084|M.marinum_M               VLTNDFVARWNGNETALAAD-ADARAELAAASAAEDLRVAPVDAGQGVGM
MAV_3496|M.avium_104                VLANDFVERWTGREETL--D-AGACEELAAAIAAGDCRVAPVDAGQGVGM
Mb0021c|M.bovis_AF2122/97           VLSNALTDQFEDTELDILHR-EEAMARYWRAVPARDYSIANVTAGQAAGL
Rv0021c|M.tuberculosis_H37Rv        VLSNALTDQFEDTELDILHR-EEAMARYWRAVAARDYSIANVTAGQAAGL
MAB_0159|M.abscessus_ATCC_1997      VLRNDFVDKWHRREAELAQHLDQARSEYQSGVAAEDYRTANLIVGEGIGQ
MUL_1961|M.ulcerans_Agy99           LLSNSLIQAWHGNESELIRRLPDLLGAFENAVAAEDFEMATVLVGEAVGL
                                    :*                                     : : .*:. . 

TH_1976|M.thermoresistible__bu      VTAAQPAAAVIERLCSRAEQLLTRWGG-
MSMEG_1660|M.smegmatis_MC2_155      VNQSLTVAETMSRLCWGAEALLRRWS--
Mflv_5156|M.gilvum_PYR-GCK          ITAVEPAAMVIARLCDDARRLLAKPPTR
Mvan_4537|M.vanbaalenii_PYR-1       LTAIEPAARVIQRLCDEAREVGQQ----
MMAR_2084|M.marinum_M               IPDGAPAGEVIEQMCSGARELLARWA--
MAV_3496|M.avium_104                IRNDATVAEVIDEMCSGAEQLLSRWGS-
Mb0021c|M.bovis_AF2122/97           VNAVLPAADVITGMAQQAARTLTAMRAV
Rv0021c|M.tuberculosis_H37Rv        VNAVLPAADVITGMAQQAARTLTAMRAV
MAB_0159|M.abscessus_ATCC_1997      VRSVESVADIIESMVAQAAAINSTSRS-
MUL_1961|M.ulcerans_Agy99           ISRVGPAADIVSEMVCDATRILNRSG--
                                    :    ...  :  :   *