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VGLRERKKLDTRRALSDAALHLMFKRGGLENVTREDIAAMAGVSVRTFNNYFTGKYEALAYRQTERMRRS IELLRERPADEPLWTAITEAVIAPLQEDMDDVYGQENALPTRRQLVEVRKILTIPQIRDVTFRGMFDEWV AVIAERTGTDPGDRYPRLVAAVVRAVGDVAMDEYAGADPPVSFPSLLREGFAAVAAGLPEPKARV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1648 | - | - | 100% (205) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 1e-09 | 30.59% (170) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 3e-06 | 25.76% (198) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 3e-06 | 36.96% (92) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1728 | - | 4e-15 | 33.97% (209) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 3e-06 | 36.96% (92) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0248c | - | 8e-15 | 34.16% (202) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3438 | - | 4e-74 | 70.15% (201) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2512 | - | 3e-11 | 26.82% (179) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4253 | - | 2e-09 | 32.24% (152) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2714 | - | 3e-74 | 70.15% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5023 | - | 2e-13 | 33.01% (206) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3438|M.marinum_M --MPDDHPPTGLRQRKKADTRRALSDAALALAFERG-LDNVTREDIANVA
MUL_2714|M.ulcerans_Agy99 --MPDDHPPTGLRQRKKADTRRALSDAALALAFERG-LDNVTREDIANVA
MSMEG_1648|M.smegmatis_MC2_155 ---------MGLRERKKLDTRRALSDAALHLMFKRGGLENVTREDIAAMA
Mflv_1728|M.gilvum_PYR-GCK MAEPRGEPVLGLRERKKRRTRATLIDAAMGLCDRQG-FDATTVDQIAAIA
Mvan_5023|M.vanbaalenii_PYR-1 -----------MRERKKRRTRATLIDAAVGLCDRQG-YDATTVDQIAHVA
TH_4253|M.thermoresistible__bu ----------------------MLTDAAVELFLRHG-YENTTVDQIAAVA
Mb3860c|M.bovis_AF2122/97 -------MVRPPQTARSERTREALRQAALVRFLAQG-VEATSAEQIAEDA
Rv3830c|M.tuberculosis_H37Rv -------MVRPPQTARSERTREALRQAALVRFLAQG-VEATSAEQIAEDA
MAB_0248c|M.abscessus_ATCC_199 -----MRPASGLREQKKSETKLALSRAALELALDRGDLAAVTVDDIADAV
MAV_2512|M.avium_104 -----MANPVGLRERRRRQTSADIRDAAVRLTLERG-FDKVTVDEICAEA
: **: :* .: ::*. .
MMAR_3438|M.marinum_M GVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRER-PAGEPLWTAIAHA
MUL_2714|M.ulcerans_Agy99 GVSLRTFNNYFTGKYEALAYRQTERMRRSIAALRER-PAGEPLWTAIAHA
MSMEG_1648|M.smegmatis_MC2_155 GVSVRTFNNYFTGKYEALAYRQTERMRRSIELLRER-PADEPLWTAITEA
Mflv_1728|M.gilvum_PYR-GCK EVSPRTFSRYFATKDAIALALIDEVLDSAAAELARQ-PLDIGNFEALRRA
Mvan_5023|M.vanbaalenii_PYR-1 EVSPRTFSRYFATKDAIALALIDEVLVHTAVELVRQ-PRYLPHMEALRRA
TH_4253|M.thermoresistible__bu DVSPRTFSRYFATKDAVIVTLLDENLDQGARALREQ-PADMNHYDALFCA
Mb3860c|M.bovis_AF2122/97 GVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDAR-PADESIIDSVQAA
Rv3830c|M.tuberculosis_H37Rv GVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDAR-PADESIIDSVQAA
MAB_0248c|M.abscessus_ATCC_199 RVSARTFRNYFTSKEDAVLFSLRGIEDNAVALLRQR-PQHEHVVDSLEAV
MAV_2512|M.avium_104 GISTRTFFNYFPNKESAIAYGPSDIPPELVADFVAAGPAPYSVVLAELIA
:* *** .:* * : * : .
MMAR_3438|M.marinum_M VLEP---LQADLHEATADEDRLPSRGELAEVRKLLMN-PQIREAASRELL
MUL_2714|M.ulcerans_Agy99 VLEP---LQADLHEATADEDRLPSRGELAEVRKLLMN-PQIREAASRELL
MSMEG_1648|M.smegmatis_MC2_155 VIAP---LQEDMDDVYGQENALPTRRQLVEVRKILTI-PQIRDVTFRGMF
Mflv_1728|M.gilvum_PYR-GCK YIAM---ARNTKLAAAGA---LTSERMLQILRIVMSS-GTLRQATVEYRA
Mvan_5023|M.vanbaalenii_PYR-1 YVAM---AEASKLAPPGA---LSAQRLLQILRIIVSS-PTLRQAAVGYRA
TH_4253|M.thermoresistible__bu YRLF---YARTKDAGPDD---LTSDRVVAMTRIIMCS-PTLRQAVGEFRP
Mb3860c|M.bovis_AF2122/97 IFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRN
Rv3830c|M.tuberculosis_H37Rv IFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRN
MAB_0248c|M.abscessus_ATCC_199 MLDL------------ATSEAFSTTVAVTRLSAQNPGLAAHDAARSEDVG
MAV_2512|M.avium_104 LAAH---------HLRDVPPRREHAANMLELAKTSPAVLAAFLADLERFQ
: .
MMAR_3438|M.marinum_M EDWRDAIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYA--------TA
MUL_2714|M.ulcerans_Agy99 EDWRDAIAERTGTDPENDMYPRLVVAVVRAVGDAAMDTYA--------TA
MSMEG_1648|M.smegmatis_MC2_155 DEWVAVIAERTGTDP-GDRYPRLVAAVVRAVGDVAMDEYA--------GA
Mflv_1728|M.gilvum_PYR-GCK SKVDRLLAERMGTSV-HDRRVKLLAAVWGAVLITAMDDLA-RKHVSGISV
Mvan_5023|M.vanbaalenii_PYR-1 GPVDAVVAERMGATV-DDRRVKLVAAVWGVVLMTALQDVC-RSAVD-FGV
TH_4253|M.thermoresistible__bu HAVNVALAERMAVDL-EDSRLRLVSSVWDAIMWASQQDLGPHTDWDTVTV
Mb3860c|M.bovis_AF2122/97 CDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLG-------ELA
Rv3830c|M.tuberculosis_H37Rv CDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLG-------ELA
MAB_0248c|M.abscessus_ATCC_199 TVVLTEVSRRAGLDPDVDLYPRLVCNAAYAVLATVIQLAVS-------GS
MAV_2512|M.avium_104 NQLTDIIVRRQGMQPDDEMAPLISALALTAVRSGIEKWASG------EAS
* . .
MMAR_3438|M.marinum_M DPPVAITELIRAGFASVAAGLPEPAKPGEQRG
MUL_2714|M.ulcerans_Agy99 DPPVAITELIRAGFASVAAGLPEPAKPGEQRG
MSMEG_1648|M.smegmatis_MC2_155 DPPVSFPSLLREGFAAVAAGLPEPKARV----
Mflv_1728|M.gilvum_PYR-GCK DDVISAFDDTYAEFAGEIAGIGQPV-------
Mvan_5023|M.vanbaalenii_PYR-1 DDVIAAVEATYAEFAGEIAGVVQPV-------
TH_4253|M.thermoresistible__bu DNLIERMEHTYRQFVAQASAIGRPV-------
Mb3860c|M.bovis_AF2122/97 RVCHVALESLRVGISDTWTTLTVSS-------
Rv3830c|M.tuberculosis_H37Rv RVCHVALESLRVGISDTWTTLTVSS-------
MAB_0248c|M.abscessus_ATCC_199 KLSKDPGALVAQGFQRLRDGLA----------
MAV_2512|M.avium_104 ETDDTPMPYVERAAALVNSIFTK---------
.