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PDADKTTRKRADARRNEQALLEAAAAAFVAAGVEVPVRDIAARAGVGMGTIYRHFPTRADLIIAVYRHQV DACADAGPQLLEQTTPYAALAKWVDQFVDFLVTKHGLAAALHSDNARYQTLHTYFLDRLLPVCAQLLDAA VASNEICSGVDPYVFMRAIGNLCIGAEDDPRYDARAMVAVLINGLRRPSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1025 | - | - | 100% (191) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2305 | - | e-107 | 100.00% (191) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3452 | - | 2e-23 | 33.51% (185) | TetR family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 7e-17 | 33.88% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 1e-17 | 36.62% (142) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 7e-17 | 33.88% (183) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 2e-15 | 32.42% (182) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1873c | - | 4e-25 | 36.52% (178) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1637 | - | 2e-08 | 31.01% (129) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4593 | - | 4e-25 | 51.92% (104) | TetR family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2712 | - | 9e-09 | 29.81% (161) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 2e-08 | 31.01% (129) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0763 | - | 1e-16 | 33.33% (177) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRARVLE
Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRARVLE
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG
Mflv_0142|M.gilvum_PYR-GCK --------------------------------MTRPLRADAARNRARVLE
Mvan_0763|M.vanbaalenii_PYR-1 --------------------------------MTRPLRADAARNRARVLE
MAB_1873c|M.abscessus_ATCC_199 ----------------------------MSEAELRTPRADAARNRDQLLA
MAV_4593|M.avium_104 ----------------------------------MVGRSDARRNRQRLLE
MSMEG_1025|M.smegmatis_MC2_155 ---------------------------MPDADKTTRKRADARRNEQALLE
MMAR_1637|M.marinum_M --------------------MSGVEGLGELPVSARQERGDAARNRELLLQ
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNRELLLQ
TH_2712|M.thermoresistible__bu ----VSLMSADELLP----ARPATDVAAPTATTAPPEREDAARNRALLLD
* ** **. :*
Mb0068c|M.bovis_AF2122/97 VAYQTFAADGLS-VPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
Rv0067c|M.tuberculosis_H37Rv VAYQTFAADGLS-VPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
MLBr_00316|M.leprae_Br4923 VAYEAFATEGLS-VPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP
Mflv_0142|M.gilvum_PYR-GCK VAYDTFAAEGLT-VPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVR
Mvan_0763|M.vanbaalenii_PYR-1 VAYDTFAAEGLG-VPIDEIARRAGVGAGTVYRHFPTKQALVVAVAEDRVR
MAB_1873c|M.abscessus_ATCC_199 AATRAFASADSE-PSMRAIARQAGVGIATLYRHFPTRESLVDAVYRDQVV
MAV_4593|M.avium_104 AATAAFTAHGAS-VSLESIARDAGVGIGTLYRHFPNREALVEAVYRAELA
MSMEG_1025|M.smegmatis_MC2_155 AAAAAFVAAGVE-VPVRDIAARAGVGMGTIYRHFPTRADLIIAVYRHQVD
MMAR_1637|M.marinum_M AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
MUL_3399|M.ulcerans_Agy99 AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
TH_2712|M.thermoresistible__bu AARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDET
.* .. . . ** **** .*::*:* .: * :
Mb0068c|M.bovis_AF2122/97 RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
Rv0067c|M.tuberculosis_H37Rv RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
MLBr_00316|M.leprae_Br4923 HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDIL
Mflv_0142|M.gilvum_PYR-GCK RIAERARTLLAVEGPGQALFVFFRDMVRS-AAVDHGLVDALMNQG-LDLE
Mvan_0763|M.vanbaalenii_PYR-1 RIVDHARTLLAAEGPGEALFVFLRDMVRS-AAADYGLVDALVGYG-LDLE
MAB_1873c|M.abscessus_ATCC_199 RLTTGAHELLGQLPPATAMRRWM-DSFGDWIATKNGMLDTLHTMIESGHI
MAV_4593|M.avium_104 EVAAAAAQLLQRHPPKAALRRWM-DRYATFVATKRGMAESLQAIFESGAL
MSMEG_1025|M.smegmatis_MC2_155 ACADAGPQLLEQTTPYAALAKWV-DQFVDFLVTKHGLAAALHSDN-ARYQ
MMAR_1637|M.marinum_M ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
MUL_3399|M.ulcerans_Agy99 ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
TH_2712|M.thermoresistible__bu AFQQAFMFGPPPLGPGAEPLERLLAYGRRRLQFVCDHHALLTDVS-REPQ
* . *
Mb0068c|M.bovis_AF2122/97 SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN
Rv0067c|M.tuberculosis_H37Rv SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN
MLBr_00316|M.leprae_Br4923 GVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN
Mflv_0142|M.gilvum_PYR-GCK AVAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQVFD
Mvan_0763|M.vanbaalenii_PYR-1 VAAPGAEAAFLATLGELLAAAQRAGTVRADVDVAVIKALLVVCKVPQVYD
MAB_1873c|M.abscessus_ATCC_199 GHA-ETRAELLKAVTTILDAGHAAGDLRADVTAEDIAASLIGIFTVAPRP
MAV_4593|M.avium_104 VPS-QTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIGIFLVSGSP
MSMEG_1025|M.smegmatis_MC2_155 TLHTYFLDRLLPVCAQLLDAAVASNEICSGVDPYVFMRAIGNLCIGAEDD
MMAR_1637|M.marinum_M TRYGAAASVHRRHVRVLLESADTTGDL--DVQTDALLALLDVDYVEHQLN
MUL_3399|M.ulcerans_Agy99 TRYGAAASVHRRHVRVLLESADTTGDL--DVQTDALLALLDVDYVEHQLN
TH_2712|M.thermoresistible__bu TRFGPPMTLHHTHIRSLLAAADADGDL--DVQADALLALTDPDYVRHQVT
:* :. .* .
Mb0068c|M.bovis_AF2122/97 A--ELAAKVTDVALDGLRANRK----
Rv0067c|M.tuberculosis_H37Rv A--ELAAKVTDVALDGLRANRK----
MLBr_00316|M.leprae_Br4923 S--ALAERVTDVVVDGLRAAR-----
Mflv_0142|M.gilvum_PYR-GCK S--EVTERVTRVIEDGLRPLR-----
Mvan_0763|M.vanbaalenii_PYR-1 G--EVSERVVRVIEDGLRVRSSV---
MAB_1873c|M.abscessus_ATCC_199 EQEAQADRLLNLLMDGLRPAARQAHS
MAV_4593|M.avium_104 E---QTGRMLDLLVAGVTR-------
MSMEG_1025|M.smegmatis_MC2_155 PR-YDARAMVAVLINGLRRPSE----
MMAR_1637|M.marinum_M DRGHTLRTLGDAWEDLARKLCGR---
MUL_3399|M.ulcerans_Agy99 DRGHTLRTLGDAWEDLARKLCGR---
TH_2712|M.thermoresistible__bu DRGVALDALADSWGDVARKLCRR---
: