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M. smegmatis MC2 155 MSMEG_0810 (-)

annotation: putative pyrimidine permease RutG
coordinates: 896271 - 897566
length: 431

TLLNWKYVESRADDDFVVAPGERLDWGRTIGIGAQHVVAMFGATFLVPVLTGFPPSTTLLFSGIGTVLFL
LITGNRLPSYLGSSFAVIAPVTAAVAADGAGSALGGLIAVGVLLIIVGAVVHLVGTHWIDVVLPPVVTGA
IVALIGFNLAPAAKNNFEQGPLVGLVTLVLLVGVLAFFRGIIGRLAIFGAVVIGYLLALVLGEVDTSAIA
AAPWVGLPQFQTPTFSLGLLPLFLPAVIALIAENIGHVKSVGQMTKTDMDPLIGRALAADGVATVLAGAG
GGSATTTYAENIGVMAATRVYSTAAYWVAAVVAIVLSLCPKVGAVISAIPAGVLGGATIVLYGLVGILGV
RIWLTNHVDFSKPVNQMTAAIPLIIGIADFTWQAGELTFTGIALGSIAALAVFHGMRLLETLGGLGRRPA
ADQAPTPPTH*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0810--100% (431)putative pyrimidine permease RutG
M. smegmatis MC2 155MSMEG_4011-e-16067.96% (412) putative pyrimidine permease RutG
M. smegmatis MC2 155MSMEG_2570-1e-3628.74% (421) xanthine/uracil permease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0188-0.081.60% (424) uracil-xanthine permease
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2932c-2e-3627.64% (398) xanthine/uracil permease
M. marinum MMMAR_4949-4e-3528.33% (413) xanthine/uracil permease
M. avium 104MAV_1023-1e-0623.32% (386) MFS transporter
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4272-8e-0526.20% (271) hypothetical protein MUL_4272
M. vanbaalenii PYR-1Mvan_0717-0.084.44% (405) uracil-xanthine permease

CLUSTAL 2.0.9 multiple sequence alignment


MAB_2932c|M.abscessus_ATCC_199      MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPL
MMAR_4949|M.marinum_M               MSAPPTSPVR------RVHPVDEVLPIPKLATYGFQHVVAFYAGAVVVPI
Mflv_0188|M.gilvum_PYR-GCK          -MTLTWKRVDSTTDPDFVVAPDERLSWPSTLGLGAQHVVAMFGATFLVPV
Mvan_0717|M.vanbaalenii_PYR-1       --MRAWTKVDSRPDPDFVVAPDERLSWPRTLGLGAQHVVAMFGATFLVPV
MSMEG_0810|M.smegmatis_MC2_155      MTLLNWKYVESRADDDFVVAPGERLDWGRTIGIGAQHVVAMFGATFLVPV
MUL_4272|M.ulcerans_Agy99           --MSTLPPPGYPVEPNSGAPGYEAAGYP---PSGYADPPPAYGPPPAYGP
MAV_1023|M.avium_104                -----------------MTATPRACNRDRVALQAVHFFMADMEAG-----
                                                       .  .          .     .          

MAB_2932c|M.abscessus_ATCC_199      LIARAIDLDAEALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTF
MMAR_4949|M.marinum_M               IIANAIDLPHQDLVKLITADLFTCGVASIIQSVGFWKIGVRLPLLQGVAF
Mflv_0188|M.gilvum_PYR-GCK          LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
Mvan_0717|M.vanbaalenii_PYR-1       LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
MSMEG_0810|M.smegmatis_MC2_155      LTG-----------FPPSTTLLFSGIGTVLFLL---ITGNRLPSYLGSSF
MUL_4272|M.ulcerans_Agy99           PPGYG---------APPPGYGPPPGYAPPPPGYGP-PPGYGPPPGYGPPP
MAV_1023|M.avium_104                ---------------------MGPFLGVLLQSRGWTTGAIGAAMTLGAIV
                                                              .           .   .   *   

MAB_2932c|M.abscessus_ATCC_199      ATLAPVIKIANDHGGGRVG--LLTVYGAVIAAGAFTFLIAPFFARLIRFF
MMAR_4949|M.marinum_M               AGVSPVIAIGLSHGGGTPS--LLYVYGAVIVAGLFTILIAPIFTKLLRFF
Mflv_0188|M.gilvum_PYR-GCK          SVIAPVTAATASHGTGSALGGIIAVGVLLIIIGAVVHVAGTRWIDIT--L
Mvan_0717|M.vanbaalenii_PYR-1       SVIAPVTAAVASEGTGSALGGIVAVGVLLILVGGVVHMVGTRWLDLT--L
MSMEG_0810|M.smegmatis_MC2_155      AVIAPVTAAVAADGAGSALGGLIAVGVLLIIVGAVVHLVGTHWIDVV--L
MUL_4272|M.ulcerans_Agy99           PGYGPPLVPGAVKPG---IIPLRPLTLSDIFNGAVGYIRANPKATLG---
MAV_1023|M.avium_104                GMVTVAPAGALVDATRHKRGCVIVVGLAAVAASAVILTSRQFWTVATAQA
                                                .        :  :    :  . .               

MAB_2932c|M.abscessus_ATCC_199      PPVVTGSVIT--IIGVSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALG
MMAR_4949|M.marinum_M               PPVVTGTLIT--IIGLCLVPVGAGDAVTNPRT--GEHDPTNIRWLLYALG
Mflv_0188|M.gilvum_PYR-GCK          PPVVTGAIVA--LIGFNLAPAAKNNFEQGPLLG---------------FV
Mvan_0717|M.vanbaalenii_PYR-1       PPIVTGAIVA--LIGFNLAPAAKNNFEQGPLLG---------------LV
MSMEG_0810|M.smegmatis_MC2_155      PPVVTGAIVA--LIGFNLAPAAKNNFEQGPLVG---------------LV
MUL_4272|M.ulcerans_Agy99           ---LTAIVVV--VMQVITLLAAIGPLEAASRFD---------------TH
MAV_1023|M.avium_104                VMCISGATIAPAMIGITLGVVGQAAFTRQNGRN------------QAYNH
                                       ::.  :.  :: .    ..                            

MAB_2932c|M.abscessus_ATCC_199      TIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVGEADWIG
MMAR_4949|M.marinum_M               TIAIIVAIQRVFSGFMATIAVLIGLVVGCVVAYGLGDMSFAKVDEASVIG
Mflv_0188|M.gilvum_PYR-GCK          TLVLLVVVLAAFRGLLGRLAIFVAVAAGYLLAVFLGEVDTSGIAAAAWIG
Mvan_0717|M.vanbaalenii_PYR-1       TLVLLVAALAFFRGMIGRLAIFVAVATGYVLALLLGEVDTSGIATAPWIG
MSMEG_0810|M.smegmatis_MC2_155      TLVLLVGVLAFFRGIIGRLAIFGAVVIGYLLALVLGEVDTSAIAAAPWVG
MUL_4272|M.ulcerans_Agy99           PSELSWGVVGAWTG-SAAAGLLVSWLGGMLLSGILTVVVGRAVFGSPITI
MAV_1023|M.avium_104                AGNMAGAALGGVAGWVFGYAGIFWLAAGFAVATIAAVLAIPGGDIDHHVA
                                    .            *     . :     *  ::                  

MAB_2932c|M.abscessus_ATCC_199      FTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGAD
MMAR_4949|M.marinum_M               FTEPFVFGMPKFDFVACLTMIIVLMITSVESTGSTLATGEIVGKRIKAAQ
Mflv_0188|M.gilvum_PYR-GCK          LPD---FQAPTFTLSVLPLFLPAVVALVAENIGHVKSVGQMT-KRDMDPL
Mvan_0717|M.vanbaalenii_PYR-1       LPE---FEAPTFTLSVLPMFLPAVIALIAENIGHVKSVSQMT-KTDLDPL
MSMEG_0810|M.smegmatis_MC2_155      LPQ---FQTPTFSLGLLPLFLPAVIALIAENIGHVKSVGQMT-KTDMDPL
MUL_4272|M.ulcerans_Agy99           SEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGATAAL
MAV_1023|M.avium_104                RGEARAAGEAPVKAMRVLARSRPLLVLAAAMVLFHLGNAAMLPLYGLAVV
                                               .            :   .                     

MAB_2932c|M.abscessus_ATCC_199      IAATVRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVI
MMAR_4949|M.marinum_M               IGNVLRADGLATVIGGIFNSFPYTAFSENVGLVRLTRVKSRWVVAAAGVV
Mflv_0188|M.gilvum_PYR-GCK          TGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAPYWIAALV
Mvan_0717|M.vanbaalenii_PYR-1       MGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAAYWVAALV
MSMEG_0810|M.smegmatis_MC2_155      IGRALAADGVATVLAGAGGGSATTTYAENIGVMAATRVYSTAAYWVAAVV
MUL_4272|M.ulcerans_Agy99           LGFPLVLL-VGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTGGF
MAV_1023|M.avium_104                ATHANPFTTVASTVVVAQAVMVPASLLAMR--IAATRGYWPAILIALTAL
                                             :.  :         :.       :  .             .

MAB_2932c|M.abscessus_ATCC_199      MMVLGVLPKTAKIVESIPAPVLG--GAAMTLFATVAVVGIQTLGKVDFND
MMAR_4949|M.marinum_M               MIVLGFLPKVAAVVSAVPSPVLG--GAALTLFATVAVVGIQTLGKVDFTD
Mflv_0188|M.gilvum_PYR-GCK          AILLSLCPKVGAVIAAIPAGVLG--GATVVLYGLVGIIGIR----IWLTN
Mvan_0717|M.vanbaalenii_PYR-1       AVALSLCPKVGAVIVAVPAGVLG--GATVVLYGLVGILGVR----IWLTN
MSMEG_0810|M.smegmatis_MC2_155      AIVLSLCPKVGAVISAIPAGVLG--GATIVLYGLVGILGVR----IWLTN
MUL_4272|M.ulcerans_Agy99           WRVLGIR-----LLTAIVVGLVG--GAISAPFGIVGQILLG----ATASE
MAV_1023|M.avium_104                PVRGVLAASVITSWGVIPVQVLDGIGAGMLSVAVPGLVARILDGTGHINV
                                         .          :   ::.  **     .  . :          . 

MAB_2932c|M.abscessus_ATCC_199      HRNLIIASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAVPGL
MMAR_4949|M.marinum_M               HRNLIIVTTSLALALWVTS--------------------YPDVAESMPSG
Mflv_0188|M.gilvum_PYR-GCK          HVDFSKPVN-----------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1       HVDFSKPIN-----------------------------------------
MSMEG_0810|M.smegmatis_MC2_155      HVDFSKPVN-----------------------------------------
MUL_4272|M.ulcerans_Agy99           GSTGMFLVG-----------------------------------------
MAV_1023|M.avium_104                GQGAVMAAQG----------------------------------------
                                                                                      

MAB_2932c|M.abscessus_ATCC_199      LQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGGGAIRLAQVNEMTLE
MMAR_4949|M.marinum_M               VDLIFGSGISIGAVAAIVLNIVFFHTGSHGPRVAGGGSITLHEVNAMTRE
Mflv_0188|M.gilvum_PYR-GCK          ---------QMTAAIPLIIGIADFTWSAGSLTFTG---IALGSIAALLIY
Mvan_0717|M.vanbaalenii_PYR-1       ---------QMTAAIPLIIGIADFTWSAGGLTFTG---IALGSIAALLIY
MSMEG_0810|M.smegmatis_MC2_155      ---------QMTAAIPLIIGIADFTWQAGELTFTG---IALGSIAALAVF
MUL_4272|M.ulcerans_Agy99           --------MTLSSIGSAISQIITAPFTAGVVVLLY----TDRRMRAEAFD
MAV_1023|M.avium_104                ---------LGGALSPVLGGAVAQHLGFRAAFLLLAG-LSLGALIIWVTF
                                                :  . :              .          :      

MAB_2932c|M.abscessus_ATCC_199      QFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEEQLE
MMAR_4949|M.marinum_M               RFTEVFGHVVQDVPWVIDRAYEHRPFADTAALREAFQDAVLTGSSEQQME
Mflv_0188|M.gilvum_PYR-GCK          HGMRLLGFRPGRERPSTVYADPAGPAPEPR--------------------
Mvan_0717|M.vanbaalenii_PYR-1       HGMRLLGFRQRG--------------------------------------
MSMEG_0810|M.smegmatis_MC2_155      HGMRLLETLGGLGRRPAADQAPTPPTH-----------------------
MUL_4272|M.ulcerans_Agy99           LVLQTGAAGGPAAVESTDTLWLTRPL------------------------
MAV_1023|M.avium_104                APMLRRAARLPAAPSDRAGAPPTATADNQAK-------------------
                                                                                      

MAB_2932c|M.abscessus_ATCC_199      LIGSFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYREHFGFP
MMAR_4949|M.marinum_M               LLNAFHDLGAEDETGRALAVDHVSLSNLDERDHNVVVELASAYREHFGFP
Mflv_0188|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155      --------------------------------------------------
MUL_4272|M.ulcerans_Agy99           --------------------------------------------------
MAV_1023|M.avium_104                --------------------------------------------------
                                                                                      

MAB_2932c|M.abscessus_ATCC_199      LVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDDLVA
MMAR_4949|M.marinum_M               LIICARETERFDRVLKNGWSRMDNSPATERAYALIEAAKIANYRFSDLVA
Mflv_0188|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155      --------------------------------------------------
MUL_4272|M.ulcerans_Agy99           --------------------------------------------------
MAV_1023|M.avium_104                --------------------------------------------------
                                                                                      

MAB_2932c|M.abscessus_ATCC_199      DANPITAARFGRFEDFHATR
MMAR_4949|M.marinum_M               DANPIASARLSRLNELH---
Mflv_0188|M.gilvum_PYR-GCK          --------------------
Mvan_0717|M.vanbaalenii_PYR-1       --------------------
MSMEG_0810|M.smegmatis_MC2_155      --------------------
MUL_4272|M.ulcerans_Agy99           --------------------
MAV_1023|M.avium_104                --------------------