For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTLTWKRVDSTTDPDFVVAPDERLSWPSTLGLGAQHVVAMFGATFLVPVLTGFPPATTLLFSGVGTILFL LITGNRLPSYLGSSFSVIAPVTAATASHGTGSALGGIIAVGVLLIIIGAVVHVAGTRWIDITLPPVVTGA IVALIGFNLAPAAKNNFEQGPLLGFVTLVLLVVVLAAFRGLLGRLAIFVAVAAGYLLAVFLGEVDTSGIA AAAWIGLPDFQAPTFTLSVLPLFLPAVVALVAENIGHVKSVGQMTKRDMDPLTGRALAADGVATTLAGFG GGSATTTYAENIGVMAATRVYSTAPYWIAALVAILLSLCPKVGAVIAAIPAGVLGGATVVLYGLVGIIGI RIWLTNHVDFSKPVNQMTAAIPLIIGIADFTWSAGSLTFTGIALGSIAALLIYHGMRLLGFRPGRERPST VYADPAGPAPEPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0188 | - | - | 100% (433) | uracil-xanthine permease |
| M. gilvum PYR-GCK | Mflv_4975 | - | 2e-09 | 25.07% (335) | sulfate transporter |
| M. gilvum PYR-GCK | Mflv_0346 | - | 7e-06 | 21.97% (396) | xanthine/uracil/vitamin C permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1768c | - | 2e-05 | 22.57% (350) | sulphate-transport transmembrane protein ABC transporter |
| M. tuberculosis H37Rv | Rv1739c | - | 2e-05 | 22.57% (350) | sulphate-transport transmembrane protein ABC transporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2932c | - | 8e-35 | 28.01% (407) | xanthine/uracil permease |
| M. marinum M | MMAR_4949 | - | 3e-37 | 27.93% (444) | xanthine/uracil permease |
| M. avium 104 | MAV_1023 | - | 8e-07 | 23.91% (389) | MFS transporter |
| M. smegmatis MC2 155 | MSMEG_0810 | - | 0.0 | 81.60% (424) | putative pyrimidine permease RutG |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0717 | - | 0.0 | 88.48% (408) | uracil-xanthine permease |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1768c|M.bovis_AF2122/97 ---MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYA
Rv1739c|M.tuberculosis_H37Rv ---MIPTMTSAGWAPGVVQFREYQRRWLRGDVLAGLTVAAYLIPQAMAYA
Mflv_0188|M.gilvum_PYR-GCK -MTLTWKRVDSTTDPDFVVAPDERLSWPSTLGLGAQHVVAMFGATFLVPV
Mvan_0717|M.vanbaalenii_PYR-1 --MRAWTKVDSRPDPDFVVAPDERLSWPRTLGLGAQHVVAMFGATFLVPV
MSMEG_0810|M.smegmatis_MC2_155 MTLLNWKYVESRADDDFVVAPGERLDWGRTIGIGAQHVVAMFGATFLVPV
MAB_2932c|M.abscessus_ATCC_199 MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPL
MMAR_4949|M.marinum_M MSAPPTSPVR------RVHPVDEVLPIPKLATYGFQHVVAFYAGAVVVPI
MAV_1023|M.avium_104 -----MTATPRACNRDRVALQAVHFFMADMEAGMGPFLGVLLQSRGWTTG
. * : . .
Mb1768c|M.bovis_AF2122/97 TVAG----------LPPAAGLWASIAPLAIYAL----LGSSRQLSIGPES
Rv1739c|M.tuberculosis_H37Rv TVAG----------LPPAAGLWASIAPLAIYAL----LGSSRQLSIGPES
Mflv_0188|M.gilvum_PYR-GCK LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
Mvan_0717|M.vanbaalenii_PYR-1 LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
MSMEG_0810|M.smegmatis_MC2_155 LTG-----------FPPSTTLLFSGIGTVLFLL---ITGNRLPSYLGSSF
MAB_2932c|M.abscessus_ATCC_199 LIARAIDLDAEALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTF
MMAR_4949|M.marinum_M IIANAIDLPHQDLVKLITADLFTCGVASIIQSVGFWKIGVRLPLLQGVAF
MAV_1023|M.avium_104 AIG--------------AAMTLGAIVGMVTVAP----AGALVDATRHKRG
. :: . *
Mb1768c|M.bovis_AF2122/97 ATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASL
Rv1739c|M.tuberculosis_H37Rv ATALMTAAVLAPMAAGDLRRYAVLAATLGLLVGLICLLAGTARLGFLASL
Mflv_0188|M.gilvum_PYR-GCK SVIAPVTAATASHGTGSALGGIIAVGVLLIIIGAVVHVAGTRWIDIT---
Mvan_0717|M.vanbaalenii_PYR-1 SVIAPVTAAVASEGTGSALGGIVAVGVLLILVGGVVHMVGTRWLDLT---
MSMEG_0810|M.smegmatis_MC2_155 AVIAPVTAAVAADGAGSALGGLIAVGVLLIIVGAVVHLVGTHWIDVV---
MAB_2932c|M.abscessus_ATCC_199 ATLAPVIKIANDHGGGRVG--LLTVYGAVIAAGAFTFLIAPFFARLIR--
MMAR_4949|M.marinum_M AGVSPVIAIGLSHGGGTPS--LLYVYGAVIVAGLFTILIAPIFTKLLR--
MAV_1023|M.avium_104 CVIVVGLAAVAASAVILTSRQFWTVATAQAVMCISGATIAPAMIGIT---
. . . .. .
Mb1768c|M.bovis_AF2122/97 LSRPVLVGYMAGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVTRVH
Rv1739c|M.tuberculosis_H37Rv RSRPVLVGYMAGIALVMISSQLGTITGTSVEGNEFFSEVHSFATSVTRVH
Mflv_0188|M.gilvum_PYR-GCK -----LPPVVTGAIVALIGFNLAPAAKNNFEQGPLLG-------------
Mvan_0717|M.vanbaalenii_PYR-1 -----LPPIVTGAIVALIGFNLAPAAKNNFEQGPLLG-------------
MSMEG_0810|M.smegmatis_MC2_155 -----LPPVVTGAIVALIGFNLAPAAKNNFEQGPLVG-------------
MAB_2932c|M.abscessus_ATCC_199 ----FFPPVVTGSVITIIGVSLLPVGIGDATRNPHSPVAAHDPGNGRWLM
MMAR_4949|M.marinum_M ----FFPPVVTGTLITIIGLCLVPVGAGDAVTNPRT--GEHDPTNIRWLL
MAV_1023|M.avium_104 -----LGVVGQAAFTRQNGRNQAYNHAGNMAG------------------
: . . .
Mb1768c|M.bovis_AF2122/97 WPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAI
Rv1739c|M.tuberculosis_H37Rv WPTFVLAMSVLALLTMLTRWAPRAPGPIIAVLAATMLVAVMSLDAKGIAI
Mflv_0188|M.gilvum_PYR-GCK ---FVTLVLLVVVLAAFRGLLGRLAIFVAVAAGYLLAVFLGEVDTSGIAA
Mvan_0717|M.vanbaalenii_PYR-1 ---LVTLVLLVAALAFFRGMIGRLAIFVAVATGYVLALLLGEVDTSGIAT
MSMEG_0810|M.smegmatis_MC2_155 ---LVTLVLLVGVLAFFRGIIGRLAIFGAVVIGYLLALVLGEVDTSAIAA
MAB_2932c|M.abscessus_ATCC_199 Y-ALGTIGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVGE
MMAR_4949|M.marinum_M Y-ALGTIAIIVAIQRVFSGFMATIAVLIGLVVGCVVAYGLGDMSFAKVDE
MAV_1023|M.avium_104 ----AALGGVAGWVFGYAGIFWLAAGFAVATIAAVLAIPGGDIDHHVARG
: . . . : . .
Mb1768c|M.bovis_AF2122/97 VGRIPSGLPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARR
Rv1739c|M.tuberculosis_H37Rv VGRIPSGLPTPGVPPVSVEDLRALIIPAAGIAIVTFTDGVLTARAFAARR
Mflv_0188|M.gilvum_PYR-GCK AAWIGLPD---FQAPTFTLSVLPLFLPAVVALVAENIGHVKSVGQMT-KR
Mvan_0717|M.vanbaalenii_PYR-1 APWIGLPE---FEAPTFTLSVLPMFLPAVIALIAENIGHVKSVSQMT-KT
MSMEG_0810|M.smegmatis_MC2_155 APWVGLPQ---FQTPTFSLGLLPLFLPAVIALIAENIGHVKSVGQMT-KT
MAB_2932c|M.abscessus_ATCC_199 ADWIGFTSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKR
MMAR_4949|M.marinum_M ASVIGFTEPFVFGMPKFDFVACLTMIIVLMITSVESTGSTLATGEIVGKR
MAV_1023|M.avium_104 EARA------AGEAPVKAMRVLARSRPLLVLAAAMVLFHLGNAAMLPLYG
* . . :
Mb1768c|M.bovis_AF2122/97 GQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVVGGRTQLYSL
Rv1739c|M.tuberculosis_H37Rv GQEVNANAELRAVGACNIAAGLTHGFPVSSSSSRTALADVVGGRTQLYSL
Mflv_0188|M.gilvum_PYR-GCK DMDPLTGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAPYW
Mvan_0717|M.vanbaalenii_PYR-1 DLDPLMGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAAYW
MSMEG_0810|M.smegmatis_MC2_155 DMDPLIGRALAADGVATVLAGAGGGSATTTYAENIGVMAATRVYSTAAYW
MAB_2932c|M.abscessus_ATCC_199 VRGADIAATVRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVVA
MMAR_4949|M.marinum_M IKAAQIGNVLRADGLATVIGGIFNSFPYTAFSENVGLVRLTRVKSRWVVA
MAV_1023|M.avium_104 LAVVATHANPFTTVASTVVVAQAVMVPASLLAMRIAATRGYWPAILIALT
: .. . . : : . .
Mb1768c|M.bovis_AF2122/97 IALGLVVIVMVFASG--LLAMFPIAALG--ALVVYAALRLIDLSEFRRLA
Rv1739c|M.tuberculosis_H37Rv IALGLVVIVMVFASG--LLAMFPIAALG--ALVVYAALRLIDLSEFRRLA
Mflv_0188|M.gilvum_PYR-GCK IAALVAILLSLCPKVGAVIAAIPAGVLGGATVVLYGLVGIIGIR----IW
Mvan_0717|M.vanbaalenii_PYR-1 VAALVAVALSLCPKVGAVIVAVPAGVLGGATVVLYGLVGILGVR----IW
MSMEG_0810|M.smegmatis_MC2_155 VAAVVAIVLSLCPKVGAVISAIPAGVLGGATIVLYGLVGILGVR----IW
MAB_2932c|M.abscessus_ATCC_199 AAGVIMMVLGVLPKTAKIVESIPAPVLGGAAMTLFATVAVVGIQTLGKVD
MMAR_4949|M.marinum_M AAGVVMIVLGFLPKVAAVVSAVPSPVLGGAALTLFATVAVVGIQTLGKVD
MAV_1023|M.avium_104 ALPVRGVLAASVITSWGVIPVQVLDGIGAGMLSVAVPGLVARILDGTGHI
: . :: :* : : : :
Mb1768c|M.bovis_AF2122/97 RFRRSELMLALATTAAVLG-------------------------------
Rv1739c|M.tuberculosis_H37Rv RFRRSELMLALATTAAVLG-------------------------------
Mflv_0188|M.gilvum_PYR-GCK LTNHVDFSKPVN--------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1 LTNHVDFSKPIN--------------------------------------
MSMEG_0810|M.smegmatis_MC2_155 LTNHVDFSKPVN--------------------------------------
MAB_2932c|M.abscessus_ATCC_199 FNDHRNLIIASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAV
MMAR_4949|M.marinum_M FTDHRNLIIVTTSLALALWVTS--------------------YPDVAESM
MAV_1023|M.avium_104 NVGQGAVMAAQG--------------------------------------
: .
Mb1768c|M.bovis_AF2122/97 ---------LGVFYGVLAAVALSILELLR-----RVAHPHDSVLGFVPGI
Rv1739c|M.tuberculosis_H37Rv ---------LGVFYGVLAAVALSILELLR-----RVAHPHDSVLGFVPGI
Mflv_0188|M.gilvum_PYR-GCK ------------QMTAAIPLIIGIADFTWSAGSLTFTG---IALGSIAAL
Mvan_0717|M.vanbaalenii_PYR-1 ------------QMTAAIPLIIGIADFTWSAGGLTFTG---IALGSIAAL
MSMEG_0810|M.smegmatis_MC2_155 ------------QMTAAIPLIIGIADFTWQAGELTFTG---IALGSIAAL
MAB_2932c|M.abscessus_ATCC_199 PGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGGGAIRLAQVNEM
MMAR_4949|M.marinum_M PSGVDLIFGSGISIGAVAAIVLNIVFFHTGSHGPRVAGGGSITLHEVNAM
MAV_1023|M.avium_104 ------------LGGALSPVLGGAVAQHLG---FRAAFLLLAGLSLGALI
. .: . : * :
Mb1768c|M.bovis_AF2122/97 AGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRR--RALTVVDQDPG
Rv1739c|M.tuberculosis_H37Rv AGMHDIDDYPQAKRVPGLVVYRYDAPLCFANAEDFRR--RALTVVDQDPG
Mflv_0188|M.gilvum_PYR-GCK LIYHGMRLLGFRPGRERPSTVYADPAGPAPEPR-----------------
Mvan_0717|M.vanbaalenii_PYR-1 LIYHGMRLLGFRQRG-----------------------------------
MSMEG_0810|M.smegmatis_MC2_155 AVFHGMRLLETLGGLGRRPAADQAPTPPTH--------------------
MAB_2932c|M.abscessus_ATCC_199 TLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEE
MMAR_4949|M.marinum_M TRERFTEVFGHVVQDVPWVIDRAYEHRPFADTAALREAFQDAVLTGSSEQ
MAV_1023|M.avium_104 IWVTFAPMLRRAARLPAAPSDRAGAPPTATADNQAK--------------
Mb1768c|M.bovis_AF2122/97 QVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESL
Rv1739c|M.tuberculosis_H37Rv QVEWFVLNAESNVEVDLTALDALDQLRTELLRRGIVFAMARVKQDLRESL
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2932c|M.abscessus_ATCC_199 QLELIGSFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYREHF
MMAR_4949|M.marinum_M QMELLNAFHDLGAEDETGRALAVDHVSLSNLDERDHNVVVELASAYREHF
MAV_1023|M.avium_104 --------------------------------------------------
Mb1768c|M.bovis_AF2122/97 RAASLLDKIGEDHIFMTLPTAVQAFRRR----------------------
Rv1739c|M.tuberculosis_H37Rv RAASLLDKIGEDHIFMTLPTAVQAFRRR----------------------
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2932c|M.abscessus_ATCC_199 GFPLVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDD
MMAR_4949|M.marinum_M GFPLIICARETERFDRVLKNGWSRMDNSPATERAYALIEAAKIANYRFSD
MAV_1023|M.avium_104 --------------------------------------------------
Mb1768c|M.bovis_AF2122/97 -----------------------
Rv1739c|M.tuberculosis_H37Rv -----------------------
Mflv_0188|M.gilvum_PYR-GCK -----------------------
Mvan_0717|M.vanbaalenii_PYR-1 -----------------------
MSMEG_0810|M.smegmatis_MC2_155 -----------------------
MAB_2932c|M.abscessus_ATCC_199 LVADANPITAARFGRFEDFHATR
MMAR_4949|M.marinum_M LVADANPIASARLSRLNELH---
MAV_1023|M.avium_104 -----------------------