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SAPPTSPVRRVHPVDEVLPIPKLATYGFQHVVAFYAGAVVVPIIIANAIDLPHQDLVKLITADLFTCGVA SIIQSVGFWKIGVRLPLLQGVAFAGVSPVIAIGLSHGGGTPSLLYVYGAVIVAGLFTILIAPIFTKLLRF FPPVVTGTLITIIGLCLVPVGAGDAVTNPRTGEHDPTNIRWLLYALGTIAIIVAIQRVFSGFMATIAVLI GLVVGCVVAYGLGDMSFAKVDEASVIGFTEPFVFGMPKFDFVACLTMIIVLMITSVESTGSTLATGEIVG KRIKAAQIGNVLRADGLATVIGGIFNSFPYTAFSENVGLVRLTRVKSRWVVAAAGVVMIVLGFLPKVAAV VSAVPSPVLGGAALTLFATVAVVGIQTLGKVDFTDHRNLIIVTTSLALALWVTSYPDVAESMPSGVDLIF GSGISIGAVAAIVLNIVFFHTGSHGPRVAGGGSITLHEVNAMTRERFTEVFGHVVQDVPWVIDRAYEHRP FADTAALREAFQDAVLTGSSEQQMELLNAFHDLGAEDETGRALAVDHVSLSNLDERDHNVVVELASAYRE HFGFPLIICARETERFDRVLKNGWSRMDNSPATERAYALIEAAKIANYRFSDLVADANPIASARLSRLNE LH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4949 | - | - | 100% (633) | xanthine/uracil permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0188 | - | 4e-37 | 27.93% (444) | uracil-xanthine permease |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2932c | - | 0.0 | 62.79% (653) | xanthine/uracil permease |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1293 | - | 0.0 | 80.88% (633) | xanthine/uracil permeases family protein |
| M. thermoresistible (build 8) | TH_1201 | - | 5e-06 | 22.76% (457) | xanthine/uracil permease |
| M. ulcerans Agy99 | MUL_0456 | - | 4e-05 | 27.71% (166) | putative OHCU decarboxylase |
| M. vanbaalenii PYR-1 | Mvan_5275 | - | 0.0 | 80.85% (632) | uracil-xanthine permease |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4949|M.marinum_M MSAPPTSPVR------RVHPVDEVLPIPKLATYGFQHVVAFYAGAVVVPI
MSMEG_1293|M.smegmatis_MC2_155 MVAPLTLQSKK-----RVHPVDEVPPVGKLATYGFQHVVAFYAGAVLVPI
Mvan_5275|M.vanbaalenii_PYR-1 MSAPTKSPKK------RVHPVDEVLPLPKLATYGFQHVVAFYAGAVLVPI
MAB_2932c|M.abscessus_ATCC_199 MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPL
Mflv_0188|M.gilvum_PYR-GCK MTLTWKRVDSTTDP-DFVVAPDERLSWPSTLGLGAQHVVAMFGATFLVPV
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_1201|M.thermoresistible__bu ----VNRLDR------FFEISARGSTVSTEVRGGLVTFIAMAYIIVLNPI
MMAR_4949|M.marinum_M IIANAIDLPHQDLVKLITADLFTCGVASIIQSVGFWKIGVRLPLLQGVAF
MSMEG_1293|M.smegmatis_MC2_155 LIATAIDLPTQDLVKLITADLFTCGIASIIQAVGFWKVGVRLPLLQGVTF
Mvan_5275|M.vanbaalenii_PYR-1 LIANAIGLSGEELVMLITADLFTCGIASIIQAVGFKNIGVRLPLLQGVTF
MAB_2932c|M.abscessus_ATCC_199 LIARAIDLDAEALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTF
Mflv_0188|M.gilvum_PYR-GCK LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_1201|M.thermoresistible__bu ILSGSADVDGNRLGFAQVSAATALTAGVMTILFG---VVARLPFAFAAGL
MMAR_4949|M.marinum_M AGVSPVIAIGLSHGGGTPS--LLYVYGAVIVAGLFTILIAPIFTKLLRFF
MSMEG_1293|M.smegmatis_MC2_155 AGVSPIIAIGLAHGGGAPS--LLYVYGAVIVAGIFTFLIAPVFIKLLRFF
Mvan_5275|M.vanbaalenii_PYR-1 AGVAPIIAIGLAHGGGTES--LLYVYGAVIVAGVFTFLIAPMFVRLLKFF
MAB_2932c|M.abscessus_ATCC_199 ATLAPVIKIANDHGGGRVG--LLTVYGAVIAAGAFTFLIAPFFARLIRFF
Mflv_0188|M.gilvum_PYR-GCK SVIAPVTAATASHGTGSALGGIIAVGVLLIIIGAVVHVAGTRWIDIT--L
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_1201|M.thermoresistible__bu GINSFLATSVVGSVSWAEAMGLVVINGLIIVLLSSTGLRRMIFDAVPMQL
MMAR_4949|M.marinum_M PPVVTG-TLITIIGLCLVPVGAGDAVTNPRT--GEHDPTNIRWLLYALGT
MSMEG_1293|M.smegmatis_MC2_155 PPVVTG-TLITIIGLCLVPVGAHDAVTNPHT--GEVDPTNLRWFLYALGT
Mvan_5275|M.vanbaalenii_PYR-1 PPVVTG-TLITIIGLCLVPIGALDAVTNPAT--HEPDPTNLRWVLYALGT
MAB_2932c|M.abscessus_ATCC_199 PPVVTG-SVITIIGVSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALGT
Mflv_0188|M.gilvum_PYR-GCK PPVVTG-AIVALIGFNLAPAAKNNFEQGPLLG---------------FVT
MUL_0456|M.ulcerans_Agy99 ---MTK-PALGLDGFNRLTD------------------------------
TH_1201|M.thermoresistible__bu KLSITAGIGLFILFIGLVNAGFIGSTGLPSP------------------P
:* : : .
MMAR_4949|M.marinum_M IAIIVAIQRVFSGFMATIAVLIGLVVGCVVAYGLGDMSFAKVDEASVIGF
MSMEG_1293|M.smegmatis_MC2_155 IAVIVAIQRIFSGFLATIAVLLGLVIGCVVAYALGDMNFDDVAQANMFGF
Mvan_5275|M.vanbaalenii_PYR-1 IAVIVAIQRLFRGFMSTIAVLLGLVAGCTVAFTLGDMNFDRVAEASMFGF
MAB_2932c|M.abscessus_ATCC_199 IGAIVLMQRFFRGFWSTIAVLLGLVAGTVVAWLAGDTDFGRVGEADWIGF
Mflv_0188|M.gilvum_PYR-GCK LVLLVVVLAAFRGLLGRLAIFVAVAAGYLLAVFLGEVDTSGIAAAAWIGL
MUL_0456|M.ulcerans_Agy99 --------------RQRMHLLFGVCSTTIWAR------------------
TH_1201|M.thermoresistible__bu TGLGVDGGGSITTVPTVLFVATLLVTGILIARRVRG--------------
: : : *
MMAR_4949|M.marinum_M TEPFVFGMPKFDFVACLTMIIVLMITSVESTGSTLATGEIVGKRIKAAQI
MSMEG_1293|M.smegmatis_MC2_155 TQPFLFGMPKFDFVACLTMIIVLMITAVESTGSTYATGEIVGKRIKASDI
Mvan_5275|M.vanbaalenii_PYR-1 TPPFAFGMPRFDIVAIITMIIVMMIIAVESTGSTIATGEIVGKRVRPSDI
MAB_2932c|M.abscessus_ATCC_199 TSPFAFGAPRFDVIAVVSLIVVLMVTAVESTGAVFATAEIVGKRVRGADI
Mflv_0188|M.gilvum_PYR-GCK PD---FQAPTFTLSVLPLFLPAVVALVAENIGHVKSVGQMT-KRDMDPLT
MUL_0456|M.ulcerans_Agy99 --------------------RVLAGAPFDDVGALLDRADRVLAQLPEAEI
TH_1201|M.thermoresistible__bu ---------------AILIGLIGGTVVAAVIEAVWHLGPAAERPGGWGLS
. .
MMAR_4949|M.marinum_M GNVLRADGLATVIGGIFNSFPYTAFSENVGLVRLTRVKSRWVVAAAGVVM
MSMEG_1293|M.smegmatis_MC2_155 GNVLRADGLATTIGGVFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIM
Mvan_5275|M.vanbaalenii_PYR-1 GNVLRADGVATTIGGIFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIM
MAB_2932c|M.abscessus_ATCC_199 AATVRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVVAAAGVIM
Mflv_0188|M.gilvum_PYR-GCK GRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAPYWIAALVA
MUL_0456|M.ulcerans_Agy99 DAALDGH-------------------------------------------
TH_1201|M.thermoresistible__bu VPALDGSPFALPDLSLIGEFSFAGFSR-------IGVLAATVFVFTLVFA
.: .
MMAR_4949|M.marinum_M IVLGFLPKVAAVVSAVPSPVLGGAALTLFATVAVVGIQTLGKVDFTDHRN
MSMEG_1293|M.smegmatis_MC2_155 ILLGFLPKVAAVVSSIPQPVLGGAALTLFATVAVVGIQTLGKVDFTDHRN
Mvan_5275|M.vanbaalenii_PYR-1 ILLGFLPKVAAIVASIPNPVLGGAALTLFATVAVVGIQTLGKVDFTDHRN
MAB_2932c|M.abscessus_ATCC_199 MVLGVLPKTAKIVESIPAPVLGGAAMTLFATVAVVGIQTLGKVDFNDHRN
Mflv_0188|M.gilvum_PYR-GCK ILLSLCPKVGAVIAAIPAGVLGGATVVLYGLVGIIGIRIWLTNHVDFSKP
MUL_0456|M.ulcerans_Agy99 ------PRIGARADNASS--------------------------------
TH_1201|M.thermoresistible__bu NFFDAMGTFTGLSREAGLAGPDGTFPRLRSALVVEGVGAVAGGAASASSN
MMAR_4949|M.marinum_M LIIVTTSLALALWVTS--------------------YPDVAESMPSGVDL
MSMEG_1293|M.smegmatis_MC2_155 LIIVTTSLAAALWATS--------------------YPDVAQALPAGIDL
Mvan_5275|M.vanbaalenii_PYR-1 VIIVTTSLALALLVTS--------------------YPDISSQLPAGLDI
MAB_2932c|M.abscessus_ATCC_199 LIIASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGIDQAVPGLLQI
Mflv_0188|M.gilvum_PYR-GCK VNQMTAAIPLIIGIAD---------------------------FTWSAGS
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_1201|M.thermoresistible__bu TVFVESGAGIGEGARTG---------------------------------
MMAR_4949|M.marinum_M IFGSGISIGAVAAIVLNIVFFHTGSHGPRVAGGGSITLHEVNAMTRERFT
MSMEG_1293|M.smegmatis_MC2_155 LFGSGISIGAISAILLNVVFFHLGGRGARVAGSGTITLDEVNAMTEQRFK
Mvan_5275|M.vanbaalenii_PYR-1 LFGSGISTGAITAIVLNIVFFHIVKKGPRVAGSGSITLDEVNAMTRERFT
MAB_2932c|M.abscessus_ATCC_199 PFSTGITMGAITAIVLNLLFFHTGSRGVAVAGGGAIRLAQVNEMTLEQFR
Mflv_0188|M.gilvum_PYR-GCK LTFTGIALGSIAALLIYHGMRLLGFR-PGRERPSTVYADPAGPAPEPR--
MUL_0456|M.ulcerans_Agy99 -----------------------AREQALVAGAGEAVRAELAEKNRK---
TH_1201|M.thermoresistible__bu ------LANLVTGALFLAAMFVSPLASVVPTEVAAAALVVVGAMMVSHLR
.
MMAR_4949|M.marinum_M EVFGHVVQDVPWVIDRAYEHRPFADTAALREAFQDAVLTGSSEQQMELLN
MSMEG_1293|M.smegmatis_MC2_155 EVFGRVVQNVPWVLERVYTSRPFTDTNALRQAFQDALLAGSADQQLELVR
Mvan_5275|M.vanbaalenii_PYR-1 EVFGHVVQGVSWAADRAFDQRPFADTAALREAFQDAVLTGNAEQQQELLD
MAB_2932c|M.abscessus_ATCC_199 RTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGSDEEQLELIG
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0456|M.ulcerans_Agy99 --------------------------------------------------
TH_1201|M.thermoresistible__bu --------------------------------------------------
MMAR_4949|M.marinum_M AFHDLGAEDETGRALAVDHVSLSNLDERDHNVVVELASAYREHFGFPLII
MSMEG_1293|M.smegmatis_MC2_155 AFPDLGAEDETGHALAVDHVALSNLDEDDHNDVVQLATAYREHFGFPLII
Mvan_5275|M.vanbaalenii_PYR-1 AFHDLGAEDETGQVLAVDHVALSNLDEEDHQDVVTLAAAYREHFGFPLII
MAB_2932c|M.abscessus_ATCC_199 SFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYREHFGFPLVV
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0456|M.ulcerans_Agy99 ---------------------------------------YEEKFGYVYLV
TH_1201|M.thermoresistible__bu -----------------------------HVDITEFSVALPVVLTVVSMP
MMAR_4949|M.marinum_M CARETERFDRVLKNGWSRMDNSPATERAYALIEAAKIANYRFSDLVADAN
MSMEG_1293|M.smegmatis_MC2_155 CARETQHFDRILQNGWSRIDNSPAAEKSFALIEIAKIVKYRFDDLVADAN
Mvan_5275|M.vanbaalenii_PYR-1 CARETERFDRVLRNGWSRMDNSPATEKAYALIEVAKIANYRFTDLVADAN
MAB_2932c|M.abscessus_ATCC_199 CARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYRFDDLVADAN
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MUL_0456|M.ulcerans_Agy99 CATG-RSAEDLLETLTDRLDNDPETERRVMRSELAKINRLRLQRLLREPA
TH_1201|M.thermoresistible__bu FSYSIANGIGIGFISWVVMRSAVGRAREVSPLLWVVAAGFLLYFARGWIE
MMAR_4949|M.marinum_M PIASARLSRLNELH---
MSMEG_1293|M.smegmatis_MC2_155 PIAAARFGRLTELR---
Mvan_5275|M.vanbaalenii_PYR-1 PIAAARFGRLNELS---
MAB_2932c|M.abscessus_ATCC_199 PITAARFGRFEDFHATR
Mflv_0188|M.gilvum_PYR-GCK -----------------
MUL_0456|M.ulcerans_Agy99 -----------------
TH_1201|M.thermoresistible__bu ALAGV------------