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RAWTKVDSRPDPDFVVAPDERLSWPRTLGLGAQHVVAMFGATFLVPVLTGFPPATTLLFSGVGTILFLLI TGNRLPSYLGSSFSVIAPVTAAVASEGTGSALGGIVAVGVLLILVGGVVHMVGTRWLDLTLPPIVTGAIV ALIGFNLAPAAKNNFEQGPLLGLVTLVLLVAALAFFRGMIGRLAIFVAVATGYVLALLLGEVDTSGIATA PWIGLPEFEAPTFTLSVLPMFLPAVIALIAENIGHVKSVSQMTKTDLDPLMGRALAADGVATTLAGFGGG SATTTYAENIGVMAATRVYSTAAYWVAALVAVALSLCPKVGAVIVAVPAGVLGGATVVLYGLVGILGVRI WLTNHVDFSKPINQMTAAIPLIIGIADFTWSAGGLTFTGIALGSIAALLIYHGMRLLGFRQRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0717 | - | - | 100% (414) | uracil-xanthine permease |
| M. vanbaalenii PYR-1 | Mvan_5275 | - | 4e-34 | 26.22% (431) | uracil-xanthine permease |
| M. vanbaalenii PYR-1 | Mvan_1159 | - | 2e-07 | 22.22% (387) | sulphate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1734 | - | 4e-08 | 24.42% (303) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0188 | - | 0.0 | 88.48% (408) | uracil-xanthine permease |
| M. tuberculosis H37Rv | Rv1707 | - | 4e-08 | 24.42% (303) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2932c | - | 4e-35 | 27.48% (404) | xanthine/uracil permease |
| M. marinum M | MMAR_4949 | - | 4e-35 | 27.70% (444) | xanthine/uracil permease |
| M. avium 104 | MAV_1023 | - | 1e-05 | 23.66% (355) | MFS transporter |
| M. smegmatis MC2 155 | MSMEG_0810 | - | 0.0 | 84.44% (405) | putative pyrimidine permease RutG |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0717|M.vanbaalenii_PYR-1 --MRAWTKVDSRPDPDFVVAPDERLSWPRTLGLGAQHVVAMFGATFLVPV
Mflv_0188|M.gilvum_PYR-GCK -MTLTWKRVDSTTDPDFVVAPDERLSWPSTLGLGAQHVVAMFGATFLVPV
MSMEG_0810|M.smegmatis_MC2_155 MTLLNWKYVESRADDDFVVAPGERLDWGRTIGIGAQHVVAMFGATFLVPV
MAB_2932c|M.abscessus_ATCC_199 MSADTTRPAAPGAQRKKVHPVDEVPSTGRLVTLGIQHVIAFYAGAVLVPL
MMAR_4949|M.marinum_M MSAPPTSPVR------RVHPVDEVLPIPKLATYGFQHVVAFYAGAVVVPI
Mb1734|M.bovis_AF2122/97 ----------------------MLQRIARELLSGVAVAIVALPLAIAFGI
Rv1707|M.tuberculosis_H37Rv ----------------------MLQRIARELLSGVAVAIVALPLAIAFGI
MAV_1023|M.avium_104 MTATPRACNRDRVALQAVHFFMADMEAGMGPFLGVLLQSRGWTTGAIGAA
*
Mvan_0717|M.vanbaalenii_PYR-1 LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
Mflv_0188|M.gilvum_PYR-GCK LTG-----------FPPATTLLFSGVGTILFLL---ITGNRLPSYLGSSF
MSMEG_0810|M.smegmatis_MC2_155 LTG-----------FPPSTTLLFSGIGTVLFLL---ITGNRLPSYLGSSF
MAB_2932c|M.abscessus_ATCC_199 LIARAIDLDAEALTMLITADLFTCGVASILQAVGFWKIGVRLPLLQGVTF
MMAR_4949|M.marinum_M IIANAIDLPHQDLVKLITADLFTCGVASIIQSVGFWKIGVRLPLLQGVAF
Mb1734|M.bovis_AF2122/97 TATG------------TSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTG
Rv1707|M.tuberculosis_H37Rv TATG------------TSQGALIGLYGAIFAGFFAAVFGGTPGQVTGPTG
MAV_1023|M.avium_104 MTLG-----------AIVGMVTVAPAGALVDATRHKRGCVIVVGLAAVAA
.::. . :
Mvan_0717|M.vanbaalenii_PYR-1 SVIAPVTAAVASEGTGSALGGIVAVGVLLILVGGVVHMVGTR-WLDLT--
Mflv_0188|M.gilvum_PYR-GCK SVIAPVTAATASHGTGSALGGIIAVGVLLIIIGAVVHVAGTR-WIDIT--
MSMEG_0810|M.smegmatis_MC2_155 AVIAPVTAAVAADGAGSALGGLIAVGVLLIIVGAVVHLVGTH-WIDVV--
MAB_2932c|M.abscessus_ATCC_199 ATLAPVIKIANDHGGGRVG--LLTVYGAVIAAGAFTFLIAPF-FARLIRF
MMAR_4949|M.marinum_M AGVSPVIAIGLSHGGGTPS--LLYVYGAVIVAGLFTILIAPI-FTKLLRF
Mb1734|M.bovis_AF2122/97 PITVVATATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRY
Rv1707|M.tuberculosis_H37Rv PITVVATATIAEHG-------LEGAFFAFILAGVFQILFGACRLGSLIRY
MAV_1023|M.avium_104 SAVILTSRQFWTVATAQAVMCISGATIAPAMIGITLGVVGQAAFTRQNGR
. . . : . * : .
Mvan_0717|M.vanbaalenii_PYR-1 LPPIVTGAIVALIGFNLAPAAKNNFEQGPLLG---------------LVT
Mflv_0188|M.gilvum_PYR-GCK LPPVVTGAIVALIGFNLAPAAKNNFEQGPLLG---------------FVT
MSMEG_0810|M.smegmatis_MC2_155 LPPVVTGAIVALIGFNLAPAAKNNFEQGPLVG---------------LVT
MAB_2932c|M.abscessus_ATCC_199 FPPVVTGSVITIIGVSLLPVGIGDATRNPHSPVAAHDPGNGRWLMYALGT
MMAR_4949|M.marinum_M FPPVVTGTLITIIGLCLVPVGAGDAVTNPRT--GEHDPTNIRWLLYALGT
Mb1734|M.bovis_AF2122/97 VPHPVISGFMGGIAILIIMTQLDQVRSSSLLV---------------LVT
Rv1707|M.tuberculosis_H37Rv VPHPVISGFMGGIAILIIMTQLDQVRSSSLLV---------------LVT
MAV_1023|M.avium_104 NQAYNHAGNMAGAALGGVAGWVFGYAG-----------------------
. : ..
Mvan_0717|M.vanbaalenii_PYR-1 LVLLVAALAFFRGMIGRLAIFVAVATGY-VLALLLGEVDTSGIATAPWIG
Mflv_0188|M.gilvum_PYR-GCK LVLLVVVLAAFRGLLGRLAIFVAVAAGY-LLAVFLGEVDTSGIAAAAWIG
MSMEG_0810|M.smegmatis_MC2_155 LVLLVGVLAFFRGIIGRLAIFGAVVIGY-LLALVLGEVDTSAIAAAPWVG
MAB_2932c|M.abscessus_ATCC_199 IGAIVLMQRFFRGFWSTIAVLLGLVAGT-VVAWLAGDTDFGRVGEADWIG
MMAR_4949|M.marinum_M IAIIVAIQRVFSGFMATIAVLIGLVVGC-VVAYGLGDMSFAKVDEASVIG
Mb1734|M.bovis_AF2122/97 VVLLLASGRFIKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVSINRTVD
Rv1707|M.tuberculosis_H37Rv VVLLLASGRFIKAIPPSLLVLVLVSSVLPLAAPWLRDLRAGPVSINRTVD
MAV_1023|M.avium_104 --IFWLAAGFAVATIAAVLAIPGGDIDHHVARGEARAAGEAPVKAMRVLA
: . : : : . : :
Mvan_0717|M.vanbaalenii_PYR-1 LPE---FEAPTFTLSVLP------MFLPAVIALIAENIGHVKSVSQMT-K
Mflv_0188|M.gilvum_PYR-GCK LPD---FQAPTFTLSVLP------LFLPAVVALVAENIGHVKSVGQMT-K
MSMEG_0810|M.smegmatis_MC2_155 LPQ---FQTPTFSLGLLP------LFLPAVIALIAENIGHVKSVGQMT-K
MAB_2932c|M.abscessus_ATCC_199 FTSPFAFGAPRFDVIAVV------SLIVVLMVTAVESTGAVFATAEIVGK
MMAR_4949|M.marinum_M FTEPFVFGMPKFDFVACL------TMIIVLMITSVESTGSTLATGEIVGK
Mb1734|M.bovis_AF2122/97 YIGEIPQAMPSFDFPQVANSTMLQVLLSAVAIALLGSLDSLLTSLVMDNI
Rv1707|M.tuberculosis_H37Rv YIGEIPQAMPSFDFPQVANSTMLQVLLSAVAIALLGSLDSLLTSLVMDNI
MAV_1023|M.avium_104 RSRPLLVLAAAMVLFHLGN----AAMLPLYGLAVVATHANPFTTVASTVV
. : . :: . :
Mvan_0717|M.vanbaalenii_PYR-1 TDLDPLMGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAAY
Mflv_0188|M.gilvum_PYR-GCK RDMDPLTGRALAADGVATTLAGFGGGSATTTYAENIGVMAATRVYSTAPY
MSMEG_0810|M.smegmatis_MC2_155 TDMDPLIGRALAADGVATVLAGAGGGSATTTYAENIGVMAATRVYSTAAY
MAB_2932c|M.abscessus_ATCC_199 RVRGADIAATVRADGIATVIGGTFNSFPYTAFSENVGLVRLTGVKSRWVV
MMAR_4949|M.marinum_M RIKAAQIGNVLRADGLATVIGGIFNSFPYTAFSENVGLVRLTRVKSRWVV
Mb1734|M.bovis_AF2122/97 RGTRHRSNKELIGQGIGNIAAGLFGG--LAGAGATVRSVVNVRNGGQTAL
Rv1707|M.tuberculosis_H37Rv RGTRHRSNKELIGQGIGNIAAGLFGG--LSGAGATVRSVVNVRNGGQTAL
MAV_1023|M.avium_104 VAQAVMVPASLLAMRIAATRGYWPAILIALTALPVRGVLAASVITSWGVI
: . :. . : .
Mvan_0717|M.vanbaalenii_PYR-1 WVAALVAVALSLCPKVGAVIVAVPAGVLGGATVVLYGLVGILGVRIWLTN
Mflv_0188|M.gilvum_PYR-GCK WIAALVAILLSLCPKVGAVIAAIPAGVLGGATVVLYGLVGIIGIRIWLTN
MSMEG_0810|M.smegmatis_MC2_155 WVAAVVAIVLSLCPKVGAVISAIPAGVLGGATIVLYGLVGILGVRIWLTN
MAB_2932c|M.abscessus_ATCC_199 AAAGVIMMVLGVLPKTAKIVESIPAPVLGGAAMTLFATVAVVGIQTLG--
MMAR_4949|M.marinum_M AAAGVVMIVLGFLPKVAAVVSAVPSPVLGGAALTLFATVAVVGIQTLG--
Mb1734|M.bovis_AF2122/97 SAATHSVVLFVFVAGLGAVVQYIPLAVLSG--ILILVAVGMFDWHAMR--
Rv1707|M.tuberculosis_H37Rv SAATHSVVLFVFVAGLGAVVQYIPLAVLSG--ILILVAVGMFDWHAMR--
MAV_1023|M.avium_104 PVQVLDGIGAGMLS---VAVPGLVARILDGTGHINVGQGAVMAAQGLG--
: . . : : :*.* .:. :
Mvan_0717|M.vanbaalenii_PYR-1 HVDFSKPINQMTAAIPLIIG----------------------------IA
Mflv_0188|M.gilvum_PYR-GCK HVDFSKPVNQMTAAIPLIIG----------------------------IA
MSMEG_0810|M.smegmatis_MC2_155 HVDFSKPVNQMTAAIPLIIG----------------------------IA
MAB_2932c|M.abscessus_ATCC_199 KVDFNDHRNLIIASTSLAMGMYVQFSQSSGPATVLDHGRGIAVPALPGID
MMAR_4949|M.marinum_M KVDFTDHRNLIIVTTSLALALWVTS--------------------YPDVA
Mb1734|M.bovis_AF2122/97 KAHVSPRGDVIVMFTTMIIT------------------------------
Rv1707|M.tuberculosis_H37Rv KAHVSPRGDVIVMFTTMIIT------------------------------
MAV_1023|M.avium_104 ----GALSPVLGGAVAQHLG------------------------------
: . :
Mvan_0717|M.vanbaalenii_PYR-1 DFTWSAGGLTFTG-IALGSIAALLIYHGMRLLGFRQRG------------
Mflv_0188|M.gilvum_PYR-GCK DFTWSAGSLTFTG-IALGSIAALLIYHGMRLLGFRPGRERPSTVYADPAG
MSMEG_0810|M.smegmatis_MC2_155 DFTWQAGELTFTG-IALGSIAALAVFHGMRLLETLGGLGRRPAADQAPTP
MAB_2932c|M.abscessus_ATCC_199 QAVPGLLQIPFSTGITMGAITAIVLNLLFFHTGSRGVAVAGGGAIRLAQV
MMAR_4949|M.marinum_M ESMPSGVDLIFGSGISIGAVAAIVLNIVFFHTGSHGPRVAGGGSITLHEV
Mb1734|M.bovis_AF2122/97 ------VVVDLTIAVMVGIALSLLVHRLRSRQRKAKVTQDDTGTYRIDGP
Rv1707|M.tuberculosis_H37Rv ------VVVDLTIAVMVGIALSLLVHRLRSRQRKAKVTQDDTGTYRIDGP
MAV_1023|M.avium_104 ----FRAAFLLLAGLSLGALIIWVTFAPMLRRAARLPAAPSDRAGAPPTA
. : : :*
Mvan_0717|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0188|M.gilvum_PYR-GCK PAPEPR--------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155 PTH-----------------------------------------------
MAB_2932c|M.abscessus_ATCC_199 NEMTLEQFRRTFGGLVQDVHWVVDRAYRQRPFADAHDLRSAFQEAMLTGS
MMAR_4949|M.marinum_M NAMTRERFTEVFGHVVQDVPWVIDRAYEHRPFADTAALREAFQDAVLTGS
Mb1734|M.bovis_AF2122/97 LSFLSVDG------------------------------------------
Rv1707|M.tuberculosis_H37Rv LSFLSVDG------------------------------------------
MAV_1023|M.avium_104 TADNQAK-------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2932c|M.abscessus_ATCC_199 DEEQLELIGSFPDLGAEDEAGEMVAVDHTILQTLDEAELNNVVSLATAYR
MMAR_4949|M.marinum_M SEQQMELLNAFHDLGAEDETGRALAVDHVSLSNLDERDHNVVVELASAYR
Mb1734|M.bovis_AF2122/97 ------------VFGSLRDGREDVSLDLQHVTYLDTSGAQALLYFIDHSE
Rv1707|M.tuberculosis_H37Rv ------------VFGSLRDGREDVSLDLQHVTYLDTSGARALLYFIDHSE
MAV_1023|M.avium_104 --------------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0188|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0810|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2932c|M.abscessus_ATCC_199 EHFGFPLVVCARETERYERLLRSGWSRMENSATSERSFALIEIAKIANYR
MMAR_4949|M.marinum_M EHFGFPLIICARETERFDRVLKNGWSRMDNSPATERAYALIEAAKIANYR
Mb1734|M.bovis_AF2122/97 KDG------VAVSIKRIPPRLESQLTALADNEQRDKLRTVLESA------
Rv1707|M.tuberculosis_H37Rv KDG------VAVSIKRIPPRLESQLTALADNEQRDKLRTVLESA------
MAV_1023|M.avium_104 --------------------------------------------------
Mvan_0717|M.vanbaalenii_PYR-1 --------------------------
Mflv_0188|M.gilvum_PYR-GCK --------------------------
MSMEG_0810|M.smegmatis_MC2_155 --------------------------
MAB_2932c|M.abscessus_ATCC_199 FDDLVADANPITAARFGRFEDFHATR
MMAR_4949|M.marinum_M FSDLVADANPIASARLSRLNELH---
Mb1734|M.bovis_AF2122/97 --------------------------
Rv1707|M.tuberculosis_H37Rv --------------------------
MAV_1023|M.avium_104 --------------------------