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VSTLPPPGYPVEPNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPPGYAPPPPGYG PPPGYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLTAIVVVVMQV ITLLAAIGPLEAASRFDTHPSELSWGVVGAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSPITISE AWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGATAALLGFPLVLLVGLLVAYLYTVLMF APVLIVLERLPLVDAITRSFALVTGGFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGATASEGSTG MFLVGMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQTGAAGGPAAVESTDTLWLTRPL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4272 | - | - | 100% (419) | hypothetical protein MUL_4272 |
| M. ulcerans Agy99 | MUL_1750 | - | 6e-26 | 30.27% (337) | proline and glycine rich transmembrane protein |
| M. ulcerans Agy99 | MUL_0202 | pra | 2e-14 | 47.87% (94) | proline-rich antigen Pra-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3714 | - | 1e-166 | 72.49% (418) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1340 | - | 9e-96 | 53.05% (377) | putative transmembrane protein |
| M. tuberculosis H37Rv | Rv3689 | - | 1e-166 | 72.25% (418) | transmembrane protein |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 4e-11 | 44.94% (89) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_0392c | - | 3e-74 | 43.90% (385) | hypothetical protein MAB_0392c |
| M. marinum M | MMAR_5199 | - | 0.0 | 98.33% (420) | hypothetical protein MMAR_5199 |
| M. avium 104 | MAV_0415 | - | 1e-128 | 61.50% (400) | hypothetical protein MAV_0415 |
| M. smegmatis MC2 155 | MSMEG_6216 | - | 2e-96 | 54.50% (367) | integral membrane protein |
| M. thermoresistible (build 8) | TH_3239 | - | 7e-86 | 53.73% (335) | PUTATIVE putative putative conserved transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5452 | - | 1e-101 | 51.35% (407) | putative transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1340|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5452|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4272|M.ulcerans_Agy99 --------------------------------------MSTLPPPGYPVE
MMAR_5199|M.marinum_M --------------------------------------MSTLPPPGYPVE
Mb3714|M.bovis_AF2122/97 MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
Rv3689|M.tuberculosis_H37Rv MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
MAV_0415|M.avium_104 -------------------MCATLRAG----ARVNVVKWSGRRQDGAHDE
MSMEG_6216|M.smegmatis_MC2_155 --------------------------------------------------
TH_3239|M.thermoresistible__bu --------------------------------------------------
MAB_0392c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_1340|M.gilvum_PYR-GCK MTYDAGGYGPAGFPPPRYP--------------------PPPGYGPPPG-
Mvan_5452|M.vanbaalenii_PYR-1 MTYNAGGYGPAGPPPPGYPAPGYP-------------GYPPAGYGAPPQY
MUL_4272|M.ulcerans_Agy99 PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPP-G
MMAR_5199|M.marinum_M PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPPPG
Mb3714|M.bovis_AF2122/97 PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
Rv3689|M.tuberculosis_H37Rv PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
MAV_0415|M.avium_104 PPVHEPRGSVSAPPPGYPVGPPPAYGSQSHYG--TQYGAQYPGQYGVH--
MSMEG_6216|M.smegmatis_MC2_155 ------------------------------------------MRPGPDGG
TH_3239|M.thermoresistible__bu --------------------------------------------------
MAB_0392c|M.abscessus_ATCC_199 MSNDEGGVTPSPLPPGPSPAYPPP---------------APGYPPAGTAG
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_1340|M.gilvum_PYR-GCK WQPP----GYGAPGYPPPYGGP------------PVLKPGVVPLRPLTLS
Mvan_5452|M.vanbaalenii_PYR-1 WQPPGYAPGYGAPGYPPQFGLP------------PVIKPGVVPLRPLTLS
MUL_4272|M.ulcerans_Agy99 YAPPPPGYGPPP-GYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MMAR_5199|M.marinum_M YGPPP-GYGPPPPGYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
Mb3714|M.bovis_AF2122/97 YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPLAPGAVKPGIIPLRPLTLS
Rv3689|M.tuberculosis_H37Rv YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPVAPGAVKPGIIPLRPLTLS
MAV_0415|M.avium_104 YGPPP---TYPPPGYPPAPAFG-PPPGYG------VLKPGIIPLRPLTLG
MSMEG_6216|M.smegmatis_MC2_155 FAPYP-----PPQAYPVHPGYA-SAPGFG------APVPGIVALRPLSLS
TH_3239|M.thermoresistible__bu VNPMA-----PMRQTALKP--------------------GVIPLRPLTLS
MAB_0392c|M.abscessus_ATCC_199 YPPPGFAYQPPPPGYQNPSAVP-----YWVTPEPPALKPGVIPLRPLDLS
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_1340|M.gilvum_PYR-GCK DIFNGAVAYVRANPKATLGLTTIVVVAAQILSLVLSLVPFTFTDMVADGL
Mvan_5452|M.vanbaalenii_PYR-1 DIFNGAVAYIRTNPKATLGLTAIVVIASQIVALLLSLWPFAFTGQVASTL
MUL_4272|M.ulcerans_Agy99 DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLAAIGPLEAASRFDT--
MMAR_5199|M.marinum_M DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLATIGPLEAASRFDT--
Mb3714|M.bovis_AF2122/97 DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTAFGDIVTG-
Rv3689|M.tuberculosis_H37Rv DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTAFGDIVTG-
MAV_0415|M.avium_104 DIFNGAVGYIRANPKATLGLTAIVVIAMQIITKAAVLGPLAAYGRFTGD-
MSMEG_6216|M.smegmatis_MC2_155 DIFNGAVAYIRRNPKATLGLTTIVVVLAQLVTLLLQVGPLAAMGGLGSEV
TH_3239|M.thermoresistible__bu DIFNGAVAYIRTNPKATLGLTAIVVVVAQLLALVLQIGSLAATGDLVSSV
MAB_0392c|M.abscessus_ATCC_199 SLYNGAIAAIRANPKTTLGLTAIVVIVSQLLIFGIQAAPATAVLTGAASF
MLBr_02395|M.leprae_Br4923 --MTDQPPPSGSNPTPAP--------------------------------
.. **..:
Mflv_1340|M.gilvum_PYR-GCK ---GEDEASVQVIVGWVASSLAGGIATALAATVLAGMLTVVIGRSVFGAG
Mvan_5452|M.vanbaalenii_PYR-1 ---DGDEASTEVLVSWMASSLATAITTGLSTTLLSGLLTVVIGRSVFGAD
MUL_4272|M.ulcerans_Agy99 ---HPSELSWGVVGAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MMAR_5199|M.marinum_M ---HPSELSWGVVGAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
Mb3714|M.bovis_AF2122/97 ---EPDELTGAVVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
Rv3689|M.tuberculosis_H37Rv ---EPDELTGAVVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
MAV_0415|M.avium_104 ---RSDELTAGVLGAWSVSVGAGVLVGWLGGMLLSGMLTVIVGRAVFGSS
MSMEG_6216|M.smegmatis_MC2_155 ---QGEAPSTGAVAMFSGATLAGVLVTQLASVLLTGMLTVIIGRSIFGGT
TH_3239|M.thermoresistible__bu ---RGDDVSTVGLSWADLASVTTAVANTLALLVLSGMLTVVIGRAVFGAG
MAB_0392c|M.abscessus_ATCC_199 DKNTEDSFGAAFGLGYIGGQLIGAVVTSLVTIILSGMLTVTIGRSVFGER
MLBr_02395|M.leprae_Br4923 ---PPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSYPPP
. : . . . :
Mflv_1340|M.gilvum_PYR-GCK ITVGEAWKRLRPRFWPLIGFTVLKMLVFLVGLVLVVGIIGATGALTTGVV
Mvan_5452|M.vanbaalenii_PYR-1 ITIGEAWRRLRPRLWALIGFTVLKTLALIVWFGVVLLIVVLAVAVIDGPA
MUL_4272|M.ulcerans_Agy99 ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MMAR_5199|M.marinum_M ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
Mb3714|M.bovis_AF2122/97 ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
Rv3689|M.tuberculosis_H37Rv ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
MAV_0415|M.avium_104 ITVGETWTKIRGRLPALLGLALLEAVVVAAIAGLVVVVIAILAAIGNAAA
MSMEG_6216|M.smegmatis_MC2_155 VTIGQAWERLRGRLLALIGLTLLEAVVLLAVVLVVIGLIAAAGAVGGAVA
TH_3239|M.thermoresistible__bu ITISEAWERLRGRLWALIGFSVLELLAVVVIVVLAVVMGAALAAAGGAGA
MAB_0392c|M.abscessus_ATCC_199 TTIKEAWQRAKPRIWALLGVAVVELVLFAVVLGFGVAVVVGLALTVGPAG
MLBr_02395|M.leprae_Br4923 PPPGGSYPPPPP------------------STGAYAPPPPGPAIRSLPKE
. ::
Mflv_1340|M.gilvum_PYR-GCK AFAVAIPLVLAAVLAAVWLSVMLTFAPVIIVLERRDIVTAVKRSFTLIKA
Mvan_5452|M.vanbaalenii_PYR-1 AFLIAAPLVLASILAAVWVSVMLTFAPAVIVLERRDIVTSVKRSFALIKS
MUL_4272|M.ulcerans_Agy99 AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MMAR_5199|M.marinum_M AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
Mb3714|M.bovis_AF2122/97 AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
Rv3689|M.tuberculosis_H37Rv AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
MAV_0415|M.avium_104 AVVLGIPLVLTVIAVLVYLYTVVLFAPVLIVLERLPVLDAITRSFRLVRR
MSMEG_6216|M.smegmatis_MC2_155 AFVMGVPLVLAAVLGALFGLTVLLFAPVLIVLERLDVFAAIARSFALVKT
TH_3239|M.thermoresistible__bu GALI-VLLFLGTVALLAYLATVLSFGPPVIVLERLGVFAAIARSFGLVRN
MAB_0392c|M.abscessus_ATCC_199 AIPAGLLLALAYFLFYLYLIPVFSLVPSVLILEQQSVFGAIGRSVSLVRK
MLBr_02395|M.leprae_Br4923 AYTFWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNVNQY
. * :. : : * : : . :
Mflv_1340|M.gilvum_PYR-GCK DFWRVFGIWLLAAIVAQFIAGAVSIPFTLGGQIAFSA-SAT---TASAML
Mvan_5452|M.vanbaalenii_PYR-1 DFWRVFGIWLLAAIVAQFIAGAVSIPFSIGGQAVLTA-SAT---TTAAMI
MUL_4272|M.ulcerans_Agy99 GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MMAR_5199|M.marinum_M GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
Mb3714|M.bovis_AF2122/97 GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
Rv3689|M.tuberculosis_H37Rv GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
MAV_0415|M.avium_104 GFWRVLGIRALAFLVTAVVANAVAVPFSIVGQVFQIS-SSG----TAFLI
MSMEG_6216|M.smegmatis_MC2_155 GFWRVLGIWLLASLVASVIASAVGAPFSIVGQLLTMS-PDG---VGMSIV
TH_3239|M.thermoresistible__bu SFWRVFGIRLLAWLVAGVISVAVAVPFSVAGGLFGLS-ADS---SALAII
MAB_0392c|M.abscessus_ATCC_199 GFWRLLGILVLTGFIVGFVSMIIGMPFILVGEVAAFAGSDPNNLGPKMLL
MLBr_02395|M.leprae_Br4923 CATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGATGS--------SIGKT
: ** *: .. .:.
Mflv_1340|M.gilvum_PYR-GCK AFALFAIGGAIGQIITGPFTAGVSVLQYADRRIRAEAFDLVLQTG---AT
Mvan_5452|M.vanbaalenii_PYR-1 SMVLFSVGGAVGQIITGPFSAGVTVLQYTDRRIRAEAFDLVLQTG---AA
MUL_4272|M.ulcerans_Agy99 GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MMAR_5199|M.marinum_M GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
Mb3714|M.bovis_AF2122/97 GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
Rv3689|M.tuberculosis_H37Rv GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
MAV_0415|M.avium_104 STAILSVGAAIGEIITAPFNAGVIVLLYTDRRMRAEAFDLLQS-----GA
MSMEG_6216|M.smegmatis_MC2_155 GLVLVAVGGTIGQIVTAPFAAGVDVLLYTDRRIRAEAFDLVLRTGAY-TP
TH_3239|M.thermoresistible__bu SLTLIAIGGAVGQIITTPFNAGVIVLLYADRRIRAEAFDLVLQTGA--TA
MAB_0392c|M.abscessus_ATCC_199 IFALAAVGAVIAQIISLPFKAAVNVLLYTDQRMRTEALDLVLQTEAR-TR
MLBr_02395|M.leprae_Br4923 VMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWD-----S
: :. . .: : : . : :.* : .: :
Mflv_1340|M.gilvum_PYR-GCK AGPYAPADSTDDLWLTR-----------
Mvan_5452|M.vanbaalenii_PYR-1 AGPQAPADSTDDLWLTGPR---------
MUL_4272|M.ulcerans_Agy99 AGGPAAVESTDTLWLTRPL---------
MMAR_5199|M.marinum_M AGGPAAVESTDNLWLTRPL---------
Mb3714|M.bovis_AF2122/97 AGGPAPVESTDNLWLTRPF---------
Rv3689|M.tuberculosis_H37Rv AGGPAPVESTDNLWLTRPF---------
MAV_0415|M.avium_104 AQGSYAAASTDNLWLTRPR---------
MSMEG_6216|M.smegmatis_MC2_155 APPAAPAESTDQLWLVR-------HF--
TH_3239|M.thermoresistible__bu GP--AHAESTDQLWLPRPTTPWAAHHPR
MAB_0392c|M.abscessus_ATCC_199 ERLGQPGIDPDSLWLPMRPPVQV-----
MLBr_02395|M.leprae_Br4923 KRQTLADKIMTTVCLPI-----------
: *