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MRAHELVLERIERDLVAGAITVGDRLPPERALAESLSVSRASVREAIRVLEAMGVIRTAAGSGPDAGAIV TADAATSIGSALRLHTATRALPIEDLVSTRILLEASALRDAAALSPRPDLAGINARLDAMDDPDLGPEEF HRLDAEFHVALTALAGNVVVEAMMAALRGAIQGYILAGVPRLADWGGVAANLRCEHRRIVTALSRGQGNK AAELARAHIEGYVDLIKS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0596 | - | - | 100% (228) | GntR family transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_0895 | - | 9e-39 | 40.00% (225) | GntR family transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_3822 | - | 2e-18 | 31.60% (231) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3086c | - | 1e-12 | 27.60% (221) | GntR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_4061 | - | 6e-15 | 29.96% (227) | regulatory protein GntR, HTH |
M. tuberculosis H37Rv | Rv3060c | - | 1e-12 | 27.60% (221) | GntR family transcriptional regulator |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4644c | - | 9e-13 | 30.73% (205) | GntR family transcriptional regulator |
M. marinum M | MMAR_3975 | - | 7e-13 | 29.65% (172) | FadR family transcriptional regulator |
M. avium 104 | MAV_2560 | - | 2e-13 | 26.07% (211) | regulatory protein GntR, HTH |
M. thermoresistible (build 8) | TH_4115 | - | 7e-14 | 31.31% (214) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3832 | - | 2e-12 | 29.07% (172) | FadR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_0606 | - | 3e-17 | 33.33% (231) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3086c|M.bovis_AF2122/97 ------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGS Rv3060c|M.tuberculosis_H37Rv ------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGS MMAR_3975|M.marinum_M ------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLLPR MUL_3832|M.ulcerans_Agy99 ------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLLPR MAV_2560|M.avium_104 --------------MEVTSLREPKMADRVATVLRRMFIRGEITEGTMLPP Mflv_4061|M.gilvum_PYR-GCK MAAPDPADSSDASEALLRPVRPLNAFEDTVERLLQTIRLGVLTPGESLPP Mvan_0606|M.vanbaalenii_PYR-1 MTAERPS--------ALSPVRQIPAHELVVDQMRRALELGQFRPGDRLPT MSMEG_0596|M.smegmatis_MC2_155 ----------------------MRAHELVLERIERDLVAGAITVGDRLPP TH_4115|M.thermoresistible__bu ---------------------VQSSYIQVADQLRDLILRGDLAVGQKLPS MAB_4644c|M.abscessus_ATCC_199 ---------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKLPG : : * * Mb3086c|M.bovis_AF2122/97 ESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPN--GGLFICEPNAGPA Rv3060c|M.tuberculosis_H37Rv ESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPN--GGLFICEPNAGPA MMAR_3975|M.marinum_M QEVLVEQFNVSLVSLREALRILETEGLVSVRRGNR--GGAVVHAPAKTSA MUL_3832|M.ulcerans_Agy99 QEVLVEQFNVSLVSLREALRILETEGLVSVRRGNR--GGAVVHAPAKASA MAV_2560|M.avium_104 ESELMERFGVSRPTLREAFRVLESESLIQVQRGVR--GGARVTRPRRETL Mflv_4061|M.gilvum_PYR-GCK ERELAARLGVSRDTVREAIKSLADAGYLVSRRGRY--GGTFLADALPAPR Mvan_0606|M.vanbaalenii_PYR-1 ERELSEMLDVSRTTVRTAVAVLERDGLIAVRRGRG--GGFTVQAPPVDPA MSMEG_0596|M.smegmatis_MC2_155 ERALAESLSVSRASVREAIRVLEAMGVIRTAAGSGPDAGAIVTADAATSI TH_4115|M.thermoresistible__bu EAEMAPLLGVSRSTIREALRILTTEHLIETRRGIQ--GGAFVAVP--DSE MAB_4644c|M.abscessus_ATCC_199 EVALCEEFGVSRATVREAIRDLKTKGLVSTRQGAG---------VFVTSD : : : ** :* *. : * . Mb3086c|M.bovis_AF2122/97 TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR Rv3060c|M.tuberculosis_H37Rv TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR MMAR_3975|M.marinum_M AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRP-DRADTLVPELKR MUL_3832|M.ulcerans_Agy99 AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRP-DRADTLVPELKR MAV_2560|M.avium_104 ARYAGLILEYEGVTVKDVYDARVTLEVPMVEQLAK---DRNPKVIAELEQ Mflv_4061|M.gilvum_PYR-GCK ADGTEMHRDD----IDDAVRLREILEVGAARMAAVR-------------T Mvan_0606|M.vanbaalenii_PYR-1 EMRRELRRNKR--AIRDAFDYRIIVETGATRLAAERR---RAIELADLRK MSMEG_0596|M.smegmatis_MC2_155 GSALRLHTATRALPIEDLVSTRILLEASALRDAAALS------PRPDLAG TH_4115|M.thermoresistible__bu RLEGMFNTSFSMLALTNQVDARSFLQAMRALEGPAAA-------LAAAAR MAB_4644c|M.abscessus_ATCC_199 RPLGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERR----------NRS : :: . Mb3086c|M.bovis_AF2122/97 AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ Rv3060c|M.tuberculosis_H37Rv AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ MMAR_3975|M.marinum_M VNEAMSEHLDDGAM-----------------FTEIGRQFHDLIVRGCGNH MUL_3832|M.ulcerans_Agy99 VNEAMSEHLDDGAM-----------------FTEIGRQFHDLIVRGCGNH MAV_2560|M.avium_104 IVERESQ-LNPGSE-----------------AVDQLTDFHAAIARLSGNS Mflv_4061|M.gilvum_PYR-GCK LAAVEREALRSRLT-----------------DVRGADPADYRRLDSRLHL Mvan_0606|M.vanbaalenii_PYR-1 LLVGMEAALDAALK-----------------DQSAQRTTEFQTLDTAFHM MSMEG_0596|M.smegmatis_MC2_155 INARLDAMDDPDLG-------------------PEEFHRLDAEFHVALTA TH_4115|M.thermoresistible__bu GGDQVEELKRTAAM------------------VDPADQEAAMQQSADFHS MAB_4644c|M.abscessus_ATCC_199 DVAAIRRALVARAK-----------------AESAGDDIEYVDADLEFHR Mb3086c|M.bovis_AF2122/97 SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ Rv3060c|M.tuberculosis_H37Rv SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ MMAR_3975|M.marinum_M TIIAVVGSLETLWTSHEQQWADESAARGTYPSLTKRRAVLNTHIKLTETI MUL_3832|M.ulcerans_Agy99 TIIAVVGSLETLWTSHEQQWADESAARGTYPSLAKRRAVLNAHIKLTETI MAV_2560|M.avium_104 TLQIVS---DMLHHIIEKANRSLQPTKGTRAEQAVRRSAK-THRMVLDMI Mflv_4061|M.gilvum_PYR-GCK AIAEAAGVPSLVPLVAQNRMRLNELLDRIPLMTRNIAHSDEQHEAIVSAI Mvan_0606|M.vanbaalenii_PYR-1 GIAQAAQNDRLLDAVADARRRMWLPVG--AIFGRLEPNANDYHESILEAI MSMEG_0596|M.smegmatis_MC2_155 LAGNVVVEAMMAALRGAIQGYILAGVPRLADWGGVAANLRCEHRRIVTAL TH_4115|M.thermoresistible__bu AILRASGNKLLEAMGRPVSAVARSKFRRTVPGLEFWERNQRAHQELLKAI MAB_4644c|M.abscessus_ATCC_199 AVVAAVHNPLLDELFDSFSVRMREAMLALLAGSAERPHDQEHHQWLFDAI . : Mb3086c|M.bovis_AF2122/97 RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV Rv3060c|M.tuberculosis_H37Rv RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV MMAR_3975|M.marinum_M AEGDVDRARRIAGRHLADTQTYVL---------------------SGRAE MUL_3832|M.ulcerans_Agy99 AEGDVDRARRIAGRHLADTQTYVL---------------------SGRAE MAV_2560|M.avium_104 KEGDAEKAGELWKRHLQKAEEFVL---------------------TGAEL Mflv_4061|M.gilvum_PYR-GCK LAGDADTAAQTMAAHVWGSAALLH----------------------GFLD Mvan_0606|M.vanbaalenii_PYR-1 ENRDPELAGSRMEAHINDTRNTLE----------------------SWLK MSMEG_0596|M.smegmatis_MC2_155 SRGQGNKAAELARAHIEGYVDLIKS------------------------- TH_4115|M.thermoresistible__bu LAGDENLAYELATRHIDEDLSPYYLP-------------------PEEAD MAB_4644c|M.abscessus_ATCC_199 VDGSTRRAVELATDQLQHVRMR---------------------------- . . Mb3086c|M.bovis_AF2122/97 GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ Rv3060c|M.tuberculosis_H37Rv GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ MMAR_3975|M.marinum_M QRIYALSPQALSRPRDMRRP------------------------------ MUL_3832|M.ulcerans_Agy99 QRIYALSPQALSRPRDMRRP------------------------------ MAV_2560|M.avium_104 STVVDLLE------------------------------------------ Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 R------------------------------------------------- MSMEG_0596|M.smegmatis_MC2_155 -------------------------------------------------- TH_4115|M.thermoresistible__bu RDGAGA-------------------------------------------- MAB_4644c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL Rv3060c|M.tuberculosis_H37Rv PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL MMAR_3975|M.marinum_M -------------------------------------------------- MUL_3832|M.ulcerans_Agy99 -------------------------------------------------- MAV_2560|M.avium_104 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0596|M.smegmatis_MC2_155 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MAB_4644c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR Rv3060c|M.tuberculosis_H37Rv DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR MMAR_3975|M.marinum_M -------------------------------------------------- MUL_3832|M.ulcerans_Agy99 -------------------------------------------------- MAV_2560|M.avium_104 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0596|M.smegmatis_MC2_155 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MAB_4644c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA Rv3060c|M.tuberculosis_H37Rv RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA MMAR_3975|M.marinum_M -------------------------------------------------- MUL_3832|M.ulcerans_Agy99 -------------------------------------------------- MAV_2560|M.avium_104 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0596|M.smegmatis_MC2_155 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MAB_4644c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 SWWL Rv3060c|M.tuberculosis_H37Rv SWWL MMAR_3975|M.marinum_M ---- MUL_3832|M.ulcerans_Agy99 ---- MAV_2560|M.avium_104 ---- Mflv_4061|M.gilvum_PYR-GCK ---- Mvan_0606|M.vanbaalenii_PYR-1 ---- MSMEG_0596|M.smegmatis_MC2_155 ---- TH_4115|M.thermoresistible__bu ---- MAB_4644c|M.abscessus_ATCC_199 ----