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M. smegmatis MC2 155 MSMEG_0596 (-)

annotation: GntR family transcriptional regulator
coordinates: 673641 - 674327
length: 228

MRAHELVLERIERDLVAGAITVGDRLPPERALAESLSVSRASVREAIRVLEAMGVIRTAAGSGPDAGAIV
TADAATSIGSALRLHTATRALPIEDLVSTRILLEASALRDAAALSPRPDLAGINARLDAMDDPDLGPEEF
HRLDAEFHVALTALAGNVVVEAMMAALRGAIQGYILAGVPRLADWGGVAANLRCEHRRIVTALSRGQGNK
AAELARAHIEGYVDLIKS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0596--100% (228)GntR family transcriptional regulator
M. smegmatis MC2 155MSMEG_0895-9e-3940.00% (225) GntR family transcriptional regulator
M. smegmatis MC2 155MSMEG_3822-2e-1831.60% (231) regulatory protein GntR, HTH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3086c-1e-1227.60% (221) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_4061-6e-1529.96% (227) regulatory protein GntR, HTH
M. tuberculosis H37RvRv3060c-1e-1227.60% (221) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4644c-9e-1330.73% (205) GntR family transcriptional regulator
M. marinum MMMAR_3975-7e-1329.65% (172) FadR family transcriptional regulator
M. avium 104MAV_2560-2e-1326.07% (211) regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_4115-7e-1431.31% (214) PUTATIVE -
M. ulcerans Agy99MUL_3832-2e-1229.07% (172) FadR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0606-3e-1733.33% (231) GntR domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3086c|M.bovis_AF2122/97           ------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGS
Rv3060c|M.tuberculosis_H37Rv        ------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGS
MMAR_3975|M.marinum_M               ------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLLPR
MUL_3832|M.ulcerans_Agy99           ------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLLPR
MAV_2560|M.avium_104                --------------MEVTSLREPKMADRVATVLRRMFIRGEITEGTMLPP
Mflv_4061|M.gilvum_PYR-GCK          MAAPDPADSSDASEALLRPVRPLNAFEDTVERLLQTIRLGVLTPGESLPP
Mvan_0606|M.vanbaalenii_PYR-1       MTAERPS--------ALSPVRQIPAHELVVDQMRRALELGQFRPGDRLPT
MSMEG_0596|M.smegmatis_MC2_155      ----------------------MRAHELVLERIERDLVAGAITVGDRLPP
TH_4115|M.thermoresistible__bu      ---------------------VQSSYIQVADQLRDLILRGDLAVGQKLPS
MAB_4644c|M.abscessus_ATCC_199      ---------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKLPG
                                                                    :   :       *  *  

Mb3086c|M.bovis_AF2122/97           ESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPN--GGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv        ESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPN--GGLFICEPNAGPA
MMAR_3975|M.marinum_M               QEVLVEQFNVSLVSLREALRILETEGLVSVRRGNR--GGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99           QEVLVEQFNVSLVSLREALRILETEGLVSVRRGNR--GGAVVHAPAKASA
MAV_2560|M.avium_104                ESELMERFGVSRPTLREAFRVLESESLIQVQRGVR--GGARVTRPRRETL
Mflv_4061|M.gilvum_PYR-GCK          ERELAARLGVSRDTVREAIKSLADAGYLVSRRGRY--GGTFLADALPAPR
Mvan_0606|M.vanbaalenii_PYR-1       ERELSEMLDVSRTTVRTAVAVLERDGLIAVRRGRG--GGFTVQAPPVDPA
MSMEG_0596|M.smegmatis_MC2_155      ERALAESLSVSRASVREAIRVLEAMGVIRTAAGSGPDAGAIVTADAATSI
TH_4115|M.thermoresistible__bu      EAEMAPLLGVSRSTIREALRILTTEHLIETRRGIQ--GGAFVAVP--DSE
MAB_4644c|M.abscessus_ATCC_199      EVALCEEFGVSRATVREAIRDLKTKGLVSTRQGAG---------VFVTSD
                                    :  :   : **   :* *.  :          *               . 

Mb3086c|M.bovis_AF2122/97           TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR
Rv3060c|M.tuberculosis_H37Rv        TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR
MMAR_3975|M.marinum_M               AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRP-DRADTLVPELKR
MUL_3832|M.ulcerans_Agy99           AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRP-DRADTLVPELKR
MAV_2560|M.avium_104                ARYAGLILEYEGVTVKDVYDARVTLEVPMVEQLAK---DRNPKVIAELEQ
Mflv_4061|M.gilvum_PYR-GCK          ADGTEMHRDD----IDDAVRLREILEVGAARMAAVR-------------T
Mvan_0606|M.vanbaalenii_PYR-1       EMRRELRRNKR--AIRDAFDYRIIVETGATRLAAERR---RAIELADLRK
MSMEG_0596|M.smegmatis_MC2_155      GSALRLHTATRALPIEDLVSTRILLEASALRDAAALS------PRPDLAG
TH_4115|M.thermoresistible__bu      RLEGMFNTSFSMLALTNQVDARSFLQAMRALEGPAAA-------LAAAAR
MAB_4644c|M.abscessus_ATCC_199      RPLGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERR----------NRS
                                                  :         ::       .                

Mb3086c|M.bovis_AF2122/97           AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ
Rv3060c|M.tuberculosis_H37Rv        AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ
MMAR_3975|M.marinum_M               VNEAMSEHLDDGAM-----------------FTEIGRQFHDLIVRGCGNH
MUL_3832|M.ulcerans_Agy99           VNEAMSEHLDDGAM-----------------FTEIGRQFHDLIVRGCGNH
MAV_2560|M.avium_104                IVERESQ-LNPGSE-----------------AVDQLTDFHAAIARLSGNS
Mflv_4061|M.gilvum_PYR-GCK          LAAVEREALRSRLT-----------------DVRGADPADYRRLDSRLHL
Mvan_0606|M.vanbaalenii_PYR-1       LLVGMEAALDAALK-----------------DQSAQRTTEFQTLDTAFHM
MSMEG_0596|M.smegmatis_MC2_155      INARLDAMDDPDLG-------------------PEEFHRLDAEFHVALTA
TH_4115|M.thermoresistible__bu      GGDQVEELKRTAAM------------------VDPADQEAAMQQSADFHS
MAB_4644c|M.abscessus_ATCC_199      DVAAIRRALVARAK-----------------AESAGDDIEYVDADLEFHR
                                                                                      

Mb3086c|M.bovis_AF2122/97           SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ
Rv3060c|M.tuberculosis_H37Rv        SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ
MMAR_3975|M.marinum_M               TIIAVVGSLETLWTSHEQQWADESAARGTYPSLTKRRAVLNTHIKLTETI
MUL_3832|M.ulcerans_Agy99           TIIAVVGSLETLWTSHEQQWADESAARGTYPSLAKRRAVLNAHIKLTETI
MAV_2560|M.avium_104                TLQIVS---DMLHHIIEKANRSLQPTKGTRAEQAVRRSAK-THRMVLDMI
Mflv_4061|M.gilvum_PYR-GCK          AIAEAAGVPSLVPLVAQNRMRLNELLDRIPLMTRNIAHSDEQHEAIVSAI
Mvan_0606|M.vanbaalenii_PYR-1       GIAQAAQNDRLLDAVADARRRMWLPVG--AIFGRLEPNANDYHESILEAI
MSMEG_0596|M.smegmatis_MC2_155      LAGNVVVEAMMAALRGAIQGYILAGVPRLADWGGVAANLRCEHRRIVTAL
TH_4115|M.thermoresistible__bu      AILRASGNKLLEAMGRPVSAVARSKFRRTVPGLEFWERNQRAHQELLKAI
MAB_4644c|M.abscessus_ATCC_199      AVVAAVHNPLLDELFDSFSVRMREAMLALLAGSAERPHDQEHHQWLFDAI
                                        .                                        :    

Mb3086c|M.bovis_AF2122/97           RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV
Rv3060c|M.tuberculosis_H37Rv        RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV
MMAR_3975|M.marinum_M               AEGDVDRARRIAGRHLADTQTYVL---------------------SGRAE
MUL_3832|M.ulcerans_Agy99           AEGDVDRARRIAGRHLADTQTYVL---------------------SGRAE
MAV_2560|M.avium_104                KEGDAEKAGELWKRHLQKAEEFVL---------------------TGAEL
Mflv_4061|M.gilvum_PYR-GCK          LAGDADTAAQTMAAHVWGSAALLH----------------------GFLD
Mvan_0606|M.vanbaalenii_PYR-1       ENRDPELAGSRMEAHINDTRNTLE----------------------SWLK
MSMEG_0596|M.smegmatis_MC2_155      SRGQGNKAAELARAHIEGYVDLIKS-------------------------
TH_4115|M.thermoresistible__bu      LAGDENLAYELATRHIDEDLSPYYLP-------------------PEEAD
MAB_4644c|M.abscessus_ATCC_199      VDGSTRRAVELATDQLQHVRMR----------------------------
                                       .          .                                   

Mb3086c|M.bovis_AF2122/97           GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ
Rv3060c|M.tuberculosis_H37Rv        GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ
MMAR_3975|M.marinum_M               QRIYALSPQALSRPRDMRRP------------------------------
MUL_3832|M.ulcerans_Agy99           QRIYALSPQALSRPRDMRRP------------------------------
MAV_2560|M.avium_104                STVVDLLE------------------------------------------
Mflv_4061|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0606|M.vanbaalenii_PYR-1       R-------------------------------------------------
MSMEG_0596|M.smegmatis_MC2_155      --------------------------------------------------
TH_4115|M.thermoresistible__bu      RDGAGA--------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3086c|M.bovis_AF2122/97           PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL
Rv3060c|M.tuberculosis_H37Rv        PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
Mflv_4061|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0606|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0596|M.smegmatis_MC2_155      --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3086c|M.bovis_AF2122/97           DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR
Rv3060c|M.tuberculosis_H37Rv        DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
Mflv_4061|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0606|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0596|M.smegmatis_MC2_155      --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3086c|M.bovis_AF2122/97           RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA
Rv3060c|M.tuberculosis_H37Rv        RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
Mflv_4061|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0606|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0596|M.smegmatis_MC2_155      --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3086c|M.bovis_AF2122/97           SWWL
Rv3060c|M.tuberculosis_H37Rv        SWWL
MMAR_3975|M.marinum_M               ----
MUL_3832|M.ulcerans_Agy99           ----
MAV_2560|M.avium_104                ----
Mflv_4061|M.gilvum_PYR-GCK          ----
Mvan_0606|M.vanbaalenii_PYR-1       ----
MSMEG_0596|M.smegmatis_MC2_155      ----
TH_4115|M.thermoresistible__bu      ----
MAB_4644c|M.abscessus_ATCC_199      ----