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VRNDPLPTQRDLPAGIPAELVAAGFEDPDEIGRGGFGVVYRCVQRALDRTVAVKVLTTDLEPDNLERFMR EQVAMGKLSGHPNIVNIFQVGTIASGRPYIVMQYHPHGSLSAKIQAAGPLGWRGALRIGVKMAGALETAH QRDTLHRDVKPANILLTEYGEPQLTDFGIARIAGGFETAEGAIMGSPAYTAPEVLLGESPTVASDVYSLA STVFTASTGHAVFERGKGEQMVAQFLRITRHPAPNLRDADLPADLSAAIEQAMSRTISDRPESAQAFGEQ LRELQRRHGLPVDDMPIPIAPPTDRPSSIASPTPSSGYPVRTLTPPAPATRFQMPSSAKRLVERARLIDV LRAQRDKKLTVIHGPTGFGKSTLAVQWAKQLAADGVAVAWLTVDDDDNNVVWFLSHVIEAIRSVMPALAS DLGDVLEEHGDDAERYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDNVASGLTVVVTSRT QSGLPMSRMRMQGEIVEIDATALRFDVSESGSFLVDLAGLDLDQTDVEELTEKTDGWVAALQLASLTLRD RDDPVQLIETMTGRHHVISEFLAENVLETLEPSTLDFLLATSIPERICGGLASALTDVPDGQAILEKIEE RDLFLRRIDDQWFRYHQLFRDFLRHRLSRERVCDLHRRACRWYAGQRLVREAVDHALAAGDETEAVRLVE NDGLYLVSGGQMATLIGLTAKLPQDIVRSNPRLQLALAWANIVLHRVPAARDALARVEATMADAGLSEDE IADMRAEADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFAAAYRYDLDEVERIQTW AAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVAEQTLRRALRIAKRSGGIHSYAGRLASSLLGEILYEK GDLAEAERLLDEGYKLGPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNRLQALAE HERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAIALQFEEASAIRRLMASDDPAARDLACRWAREWVDR LSALNRPQALLRARRLLGACLAADGRTAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELRADQEA GRWSPEWPEVPADFLQDAINSVAPQRY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0529 | - | - | 100% (1148) | serine/threonine-protein kinase PknK |
| M. smegmatis MC2 155 | MSMEG_4430 | - | 1e-81 | 31.81% (657) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5288 | - | 3e-41 | 28.12% (441) | putative serine/threonine protein kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 0.0 | 52.84% (1109) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_4809 | - | 3e-36 | 27.54% (483) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv3080c | pknK | 0.0 | 52.93% (1109) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_00017 | pknA | 6e-31 | 33.02% (315) | putative serine/threonine protein kinase |
| M. abscessus ATCC 19977 | MAB_4435 | - | 2e-33 | 33.43% (347) | serine/threonine-protein kinase PknJ |
| M. marinum M | MMAR_2576 | pknK | 0.0 | 50.63% (1108) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_0019 | - | 2e-30 | 34.67% (323) | serine/threonine protein kinases Drp72 |
| M. thermoresistible (build 8) | TH_2931 | - | 1e-29 | 37.17% (226) | PUTATIVE methylmalonyl-CoA mutase large subunit |
| M. ulcerans Agy99 | MUL_4754 | pknK_2 | 5e-79 | 39.82% (545) | serine/threonine-protein kinase transcriptional regulatory |
| M. vanbaalenii PYR-1 | Mvan_1076 | - | 3e-88 | 51.72% (319) | protein kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3107c|M.bovis_AF2122/97 -----MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVV
Rv3080c|M.tuberculosis_H37Rv -----MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVV
MMAR_2576|M.marinum_M -----MAEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGGFGIV
MSMEG_0529|M.smegmatis_MC2_155 -----MVRNDP-----LPTQRDLPAGIPAELVAAGFEDPDEIGRGGFGVV
MAB_4435|M.abscessus_ATCC_1997 -------MTSSDRSSPGPGG-QQPGDLPPGTVVSGYQIERVLGRGGMGTV
TH_2931|M.thermoresistible__bu VRTDTLCIDFQTRAAHDDGVRDALTMLPVGSMVAGYRIEGILGTGGMGTV
MLBr_00017|M.leprae_Br4923 -----------------------MSPRIGVMLSGRYRLHRLIATGGMGQV
MAV_0019|M.avium_104 -----------------------------MTLSGRYRLQRLIATGGMGQV
Mvan_1076|M.vanbaalenii_PYR-1 ----------------------MAGEIAYELAAAGFVDAVEVGRGGGGVV
MUL_4754|M.ulcerans_Agy99 ----------------------MVSQLIGQLGADGFADAVEVGRGGFGVV
Mflv_4809|M.gilvum_PYR-GCK ----------------------MGRPRIADRVVPRPDLLKRLESSAGGDL
: .. * :
Mb3107c|M.bovis_AF2122/97 YRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIVTV
Rv3080c|M.tuberculosis_H37Rv YRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIVTV
MMAR_2576|M.marinum_M YRAFQPSLDRTVAVKVLTADLDPDN--LDRFLREQRAMGRLSGHPHIVTI
MSMEG_0529|M.smegmatis_MC2_155 YRCVQRALDRTVAVKVLTTDLEPDN--LERFMREQVAMGKLSGHPNIVNI
MAB_4435|M.abscessus_ATCC_1997 YLAANPNLQRSEALKILSAQSSRDPEFRARFMREASLAASLD-HPNIVTV
TH_2931|M.thermoresistible__bu YLAKNPTLPRHDALKVLSTELSQDPGFRERFIKEADVASVLD-HPNIVSI
MLBr_00017|M.leprae_Br4923 WEAVDSRLGRRVAVKVLKGEFSSDPEFIERFRAEARTTAMLN-HPGIASV
MAV_0019|M.avium_104 WEAVDNRLGRRVAVKVLKQEFSQDPEFIERFRAEARTTAMLN-HPGIAAV
Mvan_1076|M.vanbaalenii_PYR-1 YRCHQQSLGRTVAIKVLASSLDEDD--RERFLREGYAMGGLSGHPNIVNI
MUL_4754|M.ulcerans_Agy99 YRARQVELDRVVAVKVLTADLEQNR---PRFEREQRAMARLTGHPNIVSV
Mflv_4809|M.gilvum_PYR-GCK VVLTAPAGYGKTTVTAMWDAEDRRQFAWARIDHLDDDPGHLLLHIATAVV
::. : . *: . * * . :
Mb3107c|M.bovis_AF2122/97 LQVGVL----AGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLA
Rv3080c|M.tuberculosis_H37Rv LQVGVL----AGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLA
MMAR_2576|M.marinum_M LEVGTT----ATGRPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVKVA
MSMEG_0529|M.smegmatis_MC2_155 FQVGTI----ASGRPYIVMQYHPHGSLSAKIQAAGPLGWRGALRIGVKMA
MAB_4435|M.abscessus_ATCC_1997 HNRGET----PEGDLWIAMQYVQGSDAHSESA-SGRMSLTRAVHIISEVA
TH_2931|M.thermoresistible__bu YARGET----EEGQLWIAMQYVPGTDAEAALR-AETMTPWRATHIVSEVA
MLBr_00017|M.leprae_Br4923 HDYGESHMDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTG
MAV_0019|M.avium_104 HDYGESQLDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTG
Mvan_1076|M.vanbaalenii_PYR-1 LQVGMT----EQDRPFIVMPYHARGSLADQVRREGRIPWPDALRIGVKLC
MUL_4754|M.ulcerans_Agy99 LQVGHT----PGGYPYLVMPFCSRGSVQEVITECGGLAVSEVLRLGVAVA
Mflv_4809|M.gilvum_PYR-GCK RLGAG------DDHLLNYLRGPGREPEHLLPAVVRLLEEFGPIVVILDDV
. : : :
Mb3107c|M.bovis_AF2122/97 GALEAAHRVGTLHRDVKPGNILLT----DYGEPQLTDFGIARIAGGFE--
Rv3080c|M.tuberculosis_H37Rv GALEAAHRVGTLHRDVKPGNILLT----DYGEPQLTDFGIARIAGGFE--
MMAR_2576|M.marinum_M GALEAAHRVGTLHRDVKPGNILIS----DYGEPQLTDFGIARIAGGFQ--
MSMEG_0529|M.smegmatis_MC2_155 GALETAHQRDTLHRDVKPANILLT----EYGEPQLTDFGIARIAGGFE--
MAB_4435|M.abscessus_ATCC_1997 KALDYLHARGLVHRDVKPANILLS---AGDRRIMLGDFGLTRALDDSNSV
TH_2931|M.thermoresistible__bu KALDYAHQRNVVHHDVKPANFLLSDDPGDDEKVLLSDFGVARALDDGNAA
MLBr_00017|M.leprae_Br4923 RALQIAHAAGLVHRDVKPGNILIT----PTGQVKITDFGIAKAVDAAP-V
MAV_0019|M.avium_104 RALQVAHAAGLVHRDVKPGNILIT----PTGQVKITDFGIAKAVDAAP-V
Mvan_1076|M.vanbaalenii_PYR-1 GALETAHRTGTLHRDIKPANVLVN----DYGDPQLSDFGTARIVGGYK--
MUL_4754|M.ulcerans_Agy99 AGLESAHRLGIVHRDVKPANVLLT----ELGDPAVTDFGIAHMVGGFH--
Mflv_4809|M.gilvum_PYR-GCK HKLSTPQSISALHAFVDAAPLTTT---VALLGRFLLPLDIARRRLAGN--
*. : . :* :... . . : :. ::
Mb3107c|M.bovis_AF2122/97 TATGVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCVLTGHAAYERRS
Rv3080c|M.tuberculosis_H37Rv TATGVIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRS
MMAR_2576|M.marinum_M TSTGVITGSPAFTAPEVLEGAPPTPQSDVYSLGATLFSAITGHAAFERRR
MSMEG_0529|M.smegmatis_MC2_155 TAEGAIMGSPAYTAPEVLLGESPTVASDVYSLASTVFTASTGHAVFERGK
MAB_4435|M.abscessus_ATCC_1997 TSAGNVTATIAYAAPEILSGTAVDGRADVYALGCTLFRMLTGQPPFGSGN
TH_2931|M.thermoresistible__bu MDN-SLIATLAYAAPEVIAGGAIDGRADLYSLGCTLFRMLSGRKPFHDAE
MLBr_00017|M.leprae_Br4923 TQTGMVMGTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKRPFTGDG
MAV_0019|M.avium_104 TQTGMVMGTAQYIAPEQALGHDATPASDVYSLGVVGYEVVSGKRPFSGDG
Mvan_1076|M.vanbaalenii_PYR-1 TVTGFFTGTLSYTAPEVLTGKPPTVEADVYSLGATLYAMIAGKAAHERNT
MUL_4754|M.ulcerans_Agy99 TASGVFSATPDFTAPEVLSGKEPDQASDVYGLGATLFCALTGQPPFARRD
Mflv_4809|M.gilvum_PYR-GCK -LVEVDQDALRLTAEETVAALESVRGPSDDATVATVIDLCEGWAAGVILT
: * * . .. . *
Mb3107c|M.bovis_AF2122/97 GERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADV
Rv3080c|M.tuberculosis_H37Rv GERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADV
MMAR_2576|M.marinum_M GEKVVAQFLRITSQPIPNLREEGLPADVASVIEKAMARDPADRPDSAAAF
MSMEG_0529|M.smegmatis_MC2_155 GEQMVAQFLRITRHPAPNLRDADLPADLSAAIEQAMSRTISDRPESAQAF
MAB_4435|M.abscessus_ATCC_1997 SLPAIINAHLSAPPPRISQLAP-VPESWDALIAKAMAKTPADRYQSAGEL
TH_2931|M.thermoresistible__bu GPAAIMLAHLHQEPPKLSEFVP-WSS------------------------
MLBr_00017|M.leprae_Br4923 ALTVAMKHIKEPPPPLPADLPP-NVR------------------------
MAV_0019|M.avium_104 ALTVAMKHIKEPPPPLPAELPP-NVR------------------------
Mvan_1076|M.vanbaalenii_PYR-1 DEELIAHYLRITSQPVPDLRHLGIPSDVCSAIEKAMSLESAARFDSAAEF
MUL_4754|M.ulcerans_Agy99 GEVLMAQLLRIATKSAPDLRAYGVDDDLAVVIGAALAPEPTARP-AMVEF
Mflv_4809|M.gilvum_PYR-GCK AMALRDGTAPEALAGRNNLVVEYVVEEVIDR------------------V
Mb3107c|M.bovis_AF2122/97 GEELRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPT
Rv3080c|M.tuberculosis_H37Rv GEELRDVQRRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPT
MMAR_2576|M.marinum_M GEQLRQVQREHGVAVDEMAHPVELGAPRSDLATARSTYGHD---THATPA
MSMEG_0529|M.smegmatis_MC2_155 GEQLRELQRRHGLPVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLT
MAB_4435|M.abscessus_ATCC_1997 AMAAQQILTDPAQHRQTVTQPVPATTPAPIAAPEPVHAMAPLAMADTGQS
TH_2931|M.thermoresistible__bu --PQLDXXXRPSRRRHRRTAGCAPRCPA-------------------GRR
MLBr_00017|M.leprae_Br4923 ELIEITLVKNPGMRYPSGGLFAEAVAAVR-----------------AGHR
MAV_0019|M.avium_104 ELIEITLVKNPAMRYRSGGPFADAVAAVR-----------------AGRR
Mvan_1076|M.vanbaalenii_PYR-1 GRALQEAQRHNGLTADTMAIGEPTPAAAPPEGTQALPLSVP---SDSVVL
MUL_4754|M.ulcerans_Agy99 GEALQELQATRGLAIDAMALQGAKHTGKT---------------AAARPV
Mflv_4809|M.gilvum_PYR-GCK DDDTRSFLLESAMLDRFTAEHLDAVLGR----------------VDAAWM
.
Mb3107c|M.bovis_AF2122/97 PPTPATKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLA
Rv3080c|M.tuberculosis_H37Rv PPTPATKYRPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLA
MMAR_2576|M.marinum_M PPTPATKYRPQVPARSRVSRRRLTDALSAAGRRRLILIYAPSGYGKSTLA
MSMEG_0529|M.smegmatis_MC2_155 PPAPATRFQMPSSAKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLA
MAB_4435|M.abscessus_ATCC_1997 MLKHKRIAAIIGVMVLVVASSVVAVLIWPRADEGTDPRTKASPSAAQVAP
TH_2931|M.thermoresistible__bu SARWRRR---------------------PTRSAGAPP--AGTGAASAAAP
MLBr_00017|M.leprae_Br4923 PPRPNQT---------------------PSSGRASPTTIPSSTQARAAVA
MAV_0019|M.avium_104 PPRPSQS---------------------PPPGRASPAAIPSSPTTRAAAV
Mvan_1076|M.vanbaalenii_PYR-1 PPIPAAAPPASPPAPPPPPPPDMFARSPSNSPPITPWPVAPPPYPASVAP
MUL_4754|M.ulcerans_Agy99 PPPRVRGNLPAPLSEFVGRAAELAALAELFSTARLVTLVGVGGVGKTTLA
Mflv_4809|M.gilvum_PYR-GCK LEQLATS-------------GNPFLISLDSQGDSFRYHHLFGDVLRARLR
Mb3107c|M.bovis_AF2122/97 AQWREELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGH
Rv3080c|M.tuberculosis_H37Rv AQWREELSRDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGH
MMAR_2576|M.marinum_M AQWREELVRAGVAVAWLTIDDDDNNPVWFLAHLLESIRRVHPGVAESLDH
MSMEG_0529|M.smegmatis_MC2_155 VQWAKQLAADGVAVAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGD
MAB_4435|M.abscessus_ATCC_1997 GASLAGQPNTVLDTLLPGQFDYPEG---WEKNPSPTFRSGEFNPAVPPGS
TH_2931|M.thermoresistible__bu GARHAG-----------------------------SARSG----------
MLBr_00017|M.leprae_Br4923 CGTKTPAPRR-----------------------SRPSTSG----------
MAV_0019|M.avium_104 SSGRTAAPRR-----------------------TRPATGG----------
Mvan_1076|M.vanbaalenii_PYR-1 AKNRKKTLIALAAAAAAVLLVIG-TVVIVASRDNRSGEAGGVTTAARPTA
MUL_4754|M.ulcerans_Agy99 LRAARTRAADYPAGVWVIDIGELRDGALLPGLAAGALGIHDQGSRALPEV
Mflv_4809|M.gilvum_PYR-GCK AS------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFL
Rv3080c|M.tuberculosis_H37Rv VLEEHGDDAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFL
MMAR_2576|M.marinum_M VLEEHGDDGSRYLLTSIIDALHDADEPTTLIVDDWQRVSDSQTIAALSFL
MSMEG_0529|M.smegmatis_MC2_155 VLEEHGDDAERYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYL
MAB_4435|M.abscessus_ATCC_1997 ATNIGGTPVGCNTIDPAWALRAKGRETSTLYLRDRKKPEREILIRVV---
TH_2931|M.thermoresistible__bu -----------------------------------RTPRRR---------
MLBr_00017|M.leprae_Br4923 -----------------------------------NRPPPARNTFSS---
MAV_0019|M.avium_104 -----------------------------------HRPPPARRTFSS---
Mvan_1076|M.vanbaalenii_PYR-1 EAQPGWRPIADSRIPLAAAAATEADGTIWIFGGMGADNRVSGAHEGYDPA
MUL_4754|M.ulcerans_Agy99 MVDAIGEREMLLVFDNCEHVIDEAAALIDTLLRGCPRLQIVATSRELLSL
Mflv_4809|M.gilvum_PYR-GCK -----------------------------------EPARFRELASRAADL
Mb3107c|M.bovis_AF2122/97 LDNGCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALL
Rv3080c|M.tuberculosis_H37Rv LDNGCHHLQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALL
MMAR_2576|M.marinum_M LEHGCHHLQIIVTSWSRTGLPLSRLRLADELVEIDSAALRFDSGEATSFF
MSMEG_0529|M.smegmatis_MC2_155 LDNVASGLTVVVTSRTQSGLPMSRMRMQGEIVEIDATALRFDVSESGSFL
MAB_4435|M.abscessus_ATCC_1997 ---------PAADALSTDGASDALKRCDAVAYIIPGSSTTWRCSFEFDEP
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 ---------GQRALLWAAGMLGALAIIIAVLIVINSYAGN-------EQH
MAV_0019|M.avium_104 ---------GQRALLWAAGVLGALAIIIAVLIVINSRAD--------QQQ
Mvan_1076|M.vanbaalenii_PYR-1 IDSWKGGEALPVPVQRAMSVTWQDTPVVLGGWRSEGADTKVATDQVWRVV
MUL_4754|M.ulcerans_Agy99 DGEAVFAVSPLRYPDTTTGTSRAALADYDAVALFVERAQAARPGFTLTEH
Mflv_4809|M.gilvum_PYR-GCK LEREGDIDGALVHALEAGDRARAAALVGREAVRLGFDGRAGVLARRLGML
Mb3107c|M.bovis_AF2122/97 NDAGGLRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGA
Rv3080c|M.tuberculosis_H37Rv NDAGGLRLPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGA
MMAR_2576|M.marinum_M DSLGGLSLTGNDVAALTESTDGWAAGLQLAGLSVRGGADASTLVGKLCGT
MSMEG_0529|M.smegmatis_MC2_155 VDLAGLDLDQTDVEELTEKTDGWVAALQLASLTLRDRDDPVQLIETMTGR
MAB_4435|M.abscessus_ATCC_1997 NPVQNGQKELTTTESCYMFPSGANSIRQHVSFNVVRGLLVYILASGASNR
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 QPPTPTVTDTGTPPA-----TKTLSGFPAAYCEYRVNWTNHKEISNSGLP
MAV_0019|M.avium_104 QP--PTVTDTGTPPASAPPPTKTPSGS-GAHPGLRLDWPDDGTIGASGFR
Mvan_1076|M.vanbaalenii_PYR-1 NSRWVQLPPLLQPRAAAAAAVVGDRIVVTGGVDAAGKVLDTTEVYDGSGW
MUL_4754|M.ulcerans_Agy99 NAGAIALICSRLDGVPLAVELAAARVRAMSVQQIAARLSESFALLSRGYR
Mflv_4809|M.gilvum_PYR-GCK DARTFAEQPDAAVARAWLGVTTADAELIQRSLMLALHSDHGGPLADGTPS
Mb3107c|M.bovis_AF2122/97 SDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAM
Rv3080c|M.tuberculosis_H37Rv SDVIHEFLSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAM
MMAR_2576|M.marinum_M SEVIGEFLAENVLASLEPEIVDFVLATSIPERICADLASALAQVPRGQAL
MSMEG_0529|M.smegmatis_MC2_155 HHVISEFLAENVLETLEPSTLDFLLATSIPERICGGLASALTDVPDGQAI
MAB_4435|M.abscessus_ATCC_1997 NDAAGSLSATALSFATTMKILRYGR-------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 KQAARAQLAGAIDISPVAGQT-----------------------------
MAV_0019|M.avium_104 DGPARHWTSQ----------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 TQAAPMPTPRQLLAAASDGELVYAIGGTNGTADLATVEAYDPAADTWTAM
MUL_4754|M.ulcerans_Agy99 GSPTHQQTLRCCIDWSYQRCSTAEQQLWARLSVFAGSFDLDLAHHVCAPD
Mflv_4809|M.gilvum_PYR-GCK VSVAVALISSLVGVGGVAEVIRHADTVRAAG-------------------
Mb3107c|M.bovis_AF2122/97 LEEAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRA
Rv3080c|M.tuberculosis_H37Rv LEEAEHRGLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRA
MMAR_2576|M.marinum_M LEQVAQRGLFLQPVDGEPGWFHYHQMFAEFLRRRLERDDPQRVAQLHRTA
MSMEG_0529|M.smegmatis_MC2_155 LEKIEERDLFLRRIDDQ--WFRYHQLFRDFLRHRLSR---ERVCDLHRRA
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 PALPEPRSDFGVAVTDARLVAVG--------------------GTAAGRP
MUL_4754|M.ulcerans_Agy99 TCPDDLLDQLCELVDKSILSRIDNNDDAEVRFRLLATPREYGASCLTAAD
Mflv_4809|M.gilvum_PYR-GCK ----------------------------------------------DNLV
Mb3107c|M.bovis_AF2122/97 SAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIV
Rv3080c|M.tuberculosis_H37Rv SAWFAENGYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIV
MMAR_2576|M.marinum_M ALWLKEHDRLHDAVKHALAAGDPALAVDFVEDDETNLLEQSKMTTLLEIV
MSMEG_0529|M.smegmatis_MC2_155 CRWYAGQRLVREAVDHALAAGDETEAVRLVENDGLYLVSGGQMATLIGLT
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 LKTVTALDLTTSTWSDLPDLGTARRGAAVAAVGKSVYVIGGSTGAGDGQA
MUL_4754|M.ulcerans_Agy99 HQLLRQRHLDGYRQLVAKAHAEWFSEHQVNWIRRMRRELPNVQEALQFGL
Mflv_4809|M.gilvum_PYR-GCK NPWWGAATVMKGAAEAMRGQGGRAR---------------LLLESALPVI
Mb3107c|M.bovis_AF2122/97 QKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEA
Rv3080c|M.tuberculosis_H37Rv QKLPTSMVVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEA
MMAR_2576|M.marinum_M KKLPPRLIVSRERLQLAIAWANILLQRKVPADAALNLFTKALDHADP--A
MSMEG_0529|M.smegmatis_MC2_155 AKLPQDIVRSNPRLQLALAWANIVLHRVPAARDALARVEATMADAGLSED
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 TSSAEALKLAPRTPQPAAQWR-----SLPDAPTARLMMAYTVLDDQIWIA
MUL_4754|M.ulcerans_Agy99 THAPDTALEMVADLRMLFIVSGKLKEGRRWLDRALSATPESSTKNRIRGL
Mflv_4809|M.gilvum_PYR-GCK EDLPG---------------------------------------------
Mb3107c|M.bovis_AF2122/97 TQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGN
Rv3080c|M.tuberculosis_H37Rv TQADLRAEADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGN
MMAR_2576|M.marinum_M TQADLRVEADVLQAVADTFADRIDRVDTLVAEALSRPQTFHPRVPAVAGN
MSMEG_0529|M.smegmatis_MC2_155 EIADMRAEADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAAT
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 GGIREGETLDTVETYDTRTQQWQSQPSLPIPLNHAVAATYRGEVVVIGGA
MUL_4754|M.ulcerans_Agy99 TTG---------VGFAYFQMDWPAVTQWLAEARNLLELEPYPEMDGLLCG
Mflv_4809|M.gilvum_PYR-GCK ---------------------------------------FHAAALAHLAL
Mb3107c|M.bovis_AF2122/97 TAALAAICRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRL
Rv3080c|M.tuberculosis_H37Rv TAALAAICRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRL
MMAR_2576|M.marinum_M VSAFAALYRFQFDQVRRLLAWATPYREMMG-PFVSVYARCYLGLAAKFAL
MSMEG_0529|M.smegmatis_MC2_155 VATFAAAYRYDLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAHHLML
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 TDTITQASDKVFAFRDGTWVELASLQHARAAPAAAVVDDKLVVVGGQNDK
MUL_4754|M.ulcerans_Agy99 YDGFSTLLRGEIDQARVSAERGLAITGDYDDYQVRIGCMWVMSFHSALVG
Mflv_4809|M.gilvum_PYR-GCK LDLAAGDDEAAVERCDAARTLADKYDLSDVVPMIVVYSTS--AVMSARVG
Mb3107c|M.bovis_AF2122/97 DIVAALQNFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRL
Rv3080c|M.tuberculosis_H37Rv DIVAALQNFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRL
MMAR_2576|M.marinum_M DIATALAEFRRAVEIAQSCG-TNSNATRIAGAFLGEMLHDVGELTEAKLL
MSMEG_0529|M.smegmatis_MC2_155 NNAVAEQTLRRALRIAKRSGGIHSYAGRLASSLLGEILYEKGDLAEAERL
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 QVVPQTEVFD-GQSWTQAADMPTPREHLAAVSDGVYVYTVGGRLLSADEN
MUL_4754|M.ulcerans_Agy99 DADQALHWAERAYALAESRHEVQMRTFTVSALVVGWLTRGGVEHADSALR
Mflv_4809|M.gilvum_PYR-GCK DVPAALHAVQITQTLLERLGNLSARTALLGHGLLAWTAAALQDRALLSRH
Mb3107c|M.bovis_AF2122/97 MDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQ
Rv3080c|M.tuberculosis_H37Rv MDESYLLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQ
MMAR_2576|M.marinum_M LDESYRLGPEGGGVDYLVARFVAGARVNAAHGDCAAAAERLEAGMAVADQ
MSMEG_0529|M.smegmatis_MC2_155 LDEGYKLGPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARS
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 LAAFERFDPESGNWEKLPDMPTPRGSYGAAYLDGRIVVVGGEEPTRVLPT
MUL_4754|M.ulcerans_Agy99 KALELCRASDYPFAGAQCLEGMAWTSAANNNLRRAVVLMTAAATISQITT
Mflv_4809|M.gilvum_PYR-GCK LTAAERVRHREPDAVALVQR-VERVKAMAVGGTRPLTAAELRLLPHLATH
Mb3107c|M.bovis_AF2122/97 LGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAEL
Rv3080c|M.tuberculosis_H37Rv LGLPRLAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAEL
MMAR_2576|M.marinum_M LHLPRLSAAINHERVRLGIGLSPSVSARLRDTRHNSSD--DGIVTLTYEL
MSMEG_0529|M.smegmatis_MC2_155 LSLNRLQALAEHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAIALQF
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 VEIYDIANRKWSTQAPVNTPVHGQAVAAVGSTVYCIGGADRPTHEGPVAT
MUL_4754|M.ulcerans_Agy99 GSSTTFFAAMGPFHADCERRARAELSETEFESARIQGESLTFDEAVAFAL
Mflv_4809|M.gilvum_PYR-GCK LSLQRIAEELVIGRETAKSQATSIYRKLGVSSRGQAVSEAIRIGLLAD--
Mb3107c|M.bovis_AF2122/97 DEDSAVRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIE
Rv3080c|M.tuberculosis_H37Rv DEDSAVRLLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIE
MMAR_2576|M.marinum_M DEASAIRLLSAGGSEQDRADAHRRARDLLTGIDATLRPWAALRAQLLLAE
MSMEG_0529|M.smegmatis_MC2_155 EEASAIRRLMASDDPAARDLACRWAREWVDRLSALNRPQALLRARRLLGA
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 VEALDFT-------------------------------------------
MUL_4754|M.ulcerans_Agy99 GHEW----------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA-------------
Rv3080c|M.tuberculosis_H37Rv TLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA-------------
MMAR_2576|M.marinum_M TLRAAGLQPDP--ESAGLAQRCNELGLVRLAVDAGLT-------------
MSMEG_0529|M.smegmatis_MC2_155 CLAADGRTAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELRADQE
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2931|M.thermoresistible__bu --------------------------------------------------
MLBr_00017|M.leprae_Br4923 --------------------------------------------------
MAV_0019|M.avium_104 --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4809|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ----------------------------
Rv3080c|M.tuberculosis_H37Rv ----------------------------
MMAR_2576|M.marinum_M ----------------------------
MSMEG_0529|M.smegmatis_MC2_155 AGRWSPEWPEVPADFLQDAINSVAPQRY
MAB_4435|M.abscessus_ATCC_1997 ----------------------------
TH_2931|M.thermoresistible__bu ----------------------------
MLBr_00017|M.leprae_Br4923 ----------------------------
MAV_0019|M.avium_104 ----------------------------
Mvan_1076|M.vanbaalenii_PYR-1 ----------------------------
MUL_4754|M.ulcerans_Agy99 ----------------------------
Mflv_4809|M.gilvum_PYR-GCK ----------------------------