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AGEIAYELAAAGFVDAVEVGRGGGGVVYRCHQQSLGRTVAIKVLASSLDEDDRERFLREGYAMGGLSGHP NIVNILQVGMTEQDRPFIVMPYHARGSLADQVRREGRIPWPDALRIGVKLCGALETAHRTGTLHRDIKPA NVLVNDYGDPQLSDFGTARIVGGYKTVTGFFTGTLSYTAPEVLTGKPPTVEADVYSLGATLYAMIAGKAA HERNTDEELIAHYLRITSQPVPDLRHLGIPSDVCSAIEKAMSLESAARFDSAAEFGRALQEAQRHNGLTA DTMAIGEPTPAAAPPEGTQALPLSVPSDSVVLPPIPAAAPPASPPAPPPPPPPDMFARSPSNSPPITPWP VAPPPYPASVAPAKNRKKTLIALAAAAAAVLLVIGTVVIVASRDNRSGEAGGVTTAARPTAEAQPGWRPI ADSRIPLAAAAATEADGTIWIFGGMGADNRVSGAHEGYDPAIDSWKGGEALPVPVQRAMSVTWQDTPVVL GGWRSEGADTKVATDQVWRVVNSRWVQLPPLLQPRAAAAAAVVGDRIVVTGGVDAAGKVLDTTEVYDGSG WTQAAPMPTPRQLLAAASDGELVYAIGGTNGTADLATVEAYDPAADTWTAMPALPEPRSDFGVAVTDARL VAVGGTAAGRPLKTVTALDLTTSTWSDLPDLGTARRGAAVAAVGKSVYVIGGSTGAGDGQATSSAEALKL APRTPQPAAQWRSLPDAPTARLMMAYTVLDDQIWIAGGIREGETLDTVETYDTRTQQWQSQPSLPIPLNH AVAATYRGEVVVIGGATDTITQASDKVFAFRDGTWVELASLQHARAAPAAAVVDDKLVVVGGQNDKQVVP QTEVFDGQSWTQAADMPTPREHLAAVSDGVYVYTVGGRLLSADENLAAFERFDPESGNWEKLPDMPTPRG SYGAAYLDGRIVVVGGEEPTRVLPTVEIYDIANRKWSTQAPVNTPVHGQAVAAVGSTVYCIGGADRPTHE GPVATVEALDFT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1076 | - | - | 100% (993) | protein kinase |
| M. vanbaalenii PYR-1 | Mvan_4693 | - | 8e-37 | 29.95% (414) | protein kinase |
| M. vanbaalenii PYR-1 | Mvan_0024 | - | 2e-32 | 29.17% (408) | protein kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 1e-92 | 52.87% (331) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_1389 | - | 2e-40 | 35.13% (390) | protein kinase |
| M. tuberculosis H37Rv | Rv3080c | pknK | 2e-92 | 52.87% (331) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_00016 | pknB | 3e-30 | 31.72% (290) | putative serine/threonine protein kinase |
| M. abscessus ATCC 19977 | MAB_4435 | - | 2e-33 | 33.86% (316) | serine/threonine-protein kinase PknJ |
| M. marinum M | MMAR_2576 | pknK | 1e-94 | 54.21% (321) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_0017 | - | 5e-32 | 32.69% (309) | serine/threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 3e-88 | 51.72% (319) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2631 | - | 7e-28 | 29.74% (306) | PUTATIVE serine/threonine protein kinase |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | 6e-71 | 49.27% (274) | serine/threonine-protein kinase transcriptional regulatory |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3107c|M.bovis_AF2122/97 MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQ
Rv3080c|M.tuberculosis_H37Rv MTDVDP-----HATRRDLVPNIPAELLEAGFDNVEEIGRGGFGVVYRCVQ
MMAR_2576|M.marinum_M MAEDAPYTTQAHPAQRGGISGIPGELIDAGFENVAEVGRGGFGIVYRAFQ
MSMEG_0529|M.smegmatis_MC2_155 MVRNDP-----LPTQRDLPAGIPAELVAAGFEDPDEIGRGGFGVVYRCVQ
MLBr_00016|M.leprae_Br4923 --------------------MTTPPHLSDRYELGDILGFGGMSEVHLARD
MAV_0017|M.avium_104 --------------------MTTPQHLSDRYELGEILGFGGMSEVHLARD
TH_2631|M.thermoresistible__bu --------------------MTTPQHLSDRYELGEILGFGGMSEVHLARD
Mflv_1389|M.gilvum_PYR-GCK ---------------------MTAEMLAGRYELRGLLGRGGMAEVRDGWD
Mvan_1076|M.vanbaalenii_PYR-1 -----------------MAGEIAYELAAAGFVDAVEVGRGGGGVVYRCHQ
MAB_4435|M.abscessus_ATCC_1997 ---MTSSDRSSPGPGGQQPGDLPPGTVVSGYQIERVLGRGGMGTVYLAAN
MUL_4753|M.ulcerans_Agy99 ---------------------------MDGFADAAEVGRGGFGVVYRCRQ
: :* ** . * :
Mb3107c|M.bovis_AF2122/97 PSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIVTVLQVGV
Rv3080c|M.tuberculosis_H37Rv PSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLSGHPHIVTVLQVGV
MMAR_2576|M.marinum_M PSLDRTVAVKVLTADLDPDN--LDRFLREQRAMGRLSGHPHIVTILEVGT
MSMEG_0529|M.smegmatis_MC2_155 RALDRTVAVKVLTTDLEPDN--LERFMREQVAMGKLSGHPNIVNIFQVGT
MLBr_00016|M.leprae_Br4923 IRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALN-HPSIVAVYDTGE
MAV_0017|M.avium_104 VRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALN-HPSIVAVYDTGE
TH_2631|M.thermoresistible__bu LRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALN-HPAIVAVYDTGE
Mflv_1389|M.gilvum_PYR-GCK TRLDRSVAVKLLYPSQSSDDSVRRRFEDEARSAARLS-HPNIVAIHDFGE
Mvan_1076|M.vanbaalenii_PYR-1 QSLGRTVAIKVLASSLDEDD--RERFLREGYAMGGLSGHPNIVNILQVGM
MAB_4435|M.abscessus_ATCC_1997 PNLQRSEALKILSAQSSRDPEFRARFMREASLAASLD-HPNIVTVHNRGE
MUL_4753|M.ulcerans_Agy99 VDLDRVVAIKVLTIDLDENR---PRFEREQRAMAKLTGHPNIVSVLQIGE
* * *:*:* . : ** * . * ** ** : : *
Mb3107c|M.bovis_AF2122/97 LAGG---RPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAA
Rv3080c|M.tuberculosis_H37Rv LAGG---RPFIVMPYHAKNSLETLIRRHGPLDWRETLSIGVKLAGALEAA
MMAR_2576|M.marinum_M TATG---RPFLVMPYHQNDSLEALVRRNGPLDWGEVVRLGVKVAGALEAA
MSMEG_0529|M.smegmatis_MC2_155 IASG---RPYIVMQYHPHGSLSAKIQAAGPLGWRGALRIGVKMAGALETA
MLBr_00016|M.leprae_Br4923 AETSAGPLPYIVMEYVDGATLRDIVHTDGPMPPQQAIEIVADACQALNFS
MAV_0017|M.avium_104 AETPSGPLPYIVMEYVDGVTLRDIVHTDGPLPPRRAIEIIADACQALNFS
TH_2631|M.thermoresistible__bu AETPTGPLPYIVMEYVDGVTLRDIVHTDGPMEPKRAIEVIADACQALNFS
Mflv_1389|M.gilvum_PYR-GCK HDS----APFIVMERLPGRTLADVIE-QGPMPAPQVRRVLDEVLAALSVA
Mvan_1076|M.vanbaalenii_PYR-1 TEQD---RPFIVMPYHARGSLADQVRREGRIPWPDALRIGVKLCGALETA
MAB_4435|M.abscessus_ATCC_1997 TPEG---DLWIAMQYVQG-SDAHSESASGRMSLTRAVHIISEVAKALDYL
MUL_4753|M.ulcerans_Agy99 TRDG---HPYLVMPYCRRGSVQTEISRLGRLSLADILQLGVALAAGLESA
::.* : * : : .*.
Mb3107c|M.bovis_AF2122/97 HRVGTLHRDVKPGNILLTDY-GEPQLTDFGIARIAGGF---ETATGVIAG
Rv3080c|M.tuberculosis_H37Rv HRVGTLHRDVKPGNILLTDY-GEPQLTDFGIARIAGGF---ETATGVIAG
MMAR_2576|M.marinum_M HRVGTLHRDVKPGNILISDY-GEPQLTDFGIARIAGGF---QTSTGVITG
MSMEG_0529|M.smegmatis_MC2_155 HQRDTLHRDVKPANILLTEY-GEPQLTDFGIARIAGGF---ETAEGAIMG
MLBr_00016|M.leprae_Br4923 HQNGIIHRDVKPANIMISAT-NAVKVMDFGIARAIADS-TSVTQTAAVIG
MAV_0017|M.avium_104 HQNGIIHRDVKPANIMISTT-NAVKVMDFGIARAIADSGNSVTQTAAVIG
TH_2631|M.thermoresistible__bu HQHGIIHRDVKPANIMISKT-GAVKVMDFGIARAIADS-NSVTQTAAVIG
Mflv_1389|M.gilvum_PYR-GCK HAAGVLHRDIKPANILLTTAGDSVKVADFGIAKSAGAA---HTATGQIVG
Mvan_1076|M.vanbaalenii_PYR-1 HRTGTLHRDIKPANVLVNDY-GDPQLSDFGTARIVGGY---KTVTGFFTG
MAB_4435|M.abscessus_ATCC_1997 HARGLVHRDVKPANILLSAGDRRIMLGDFGLTRALDDS-NSVTSAGNVTA
MUL_4753|M.ulcerans_Agy99 HRLDILHRDIKPANVLLTDF-GEPALTDFGLAHMAGGF---RTATGLFTA
* . :***:**.*:::. : *** :: * . . .
Mb3107c|M.bovis_AF2122/97 SPAFTAPEVLEGASPTPASDVYSLGATLFCVLTGHAAYERRSGERVIAQF
Rv3080c|M.tuberculosis_H37Rv SPAFTAPEVLEGASPTPASDVYSLGATLFCALTGHAAYERRSGERVIAQF
MMAR_2576|M.marinum_M SPAFTAPEVLEGAPPTPQSDVYSLGATLFSAITGHAAFERRRGEKVVAQF
MSMEG_0529|M.smegmatis_MC2_155 SPAYTAPEVLLGESPTVASDVYSLASTVFTASTGHAVFERGKGEQMVAQF
MLBr_00016|M.leprae_Br4923 TAQYLSPEQARGDSVDARSDVYSLGCVLYEILTGEPPFIGDSPVSVAYQH
MAV_0017|M.avium_104 TAQYLSPEQARGDAVDARSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQH
TH_2631|M.thermoresistible__bu TAQYLSPEQARGETVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQH
Mflv_1389|M.gilvum_PYR-GCK TLCYLSPERVMGAPASVADDLYAVGVMGYEALLGRRAFPQDNPAALARAI
Mvan_1076|M.vanbaalenii_PYR-1 TLSYTAPEVLTGKPPTVEADVYSLGATLYAMIAGKAAHERNTDEELIAHY
MAB_4435|M.abscessus_ATCC_1997 TIAYAAPEILSGTAVDGRADVYALGCTLFRMLTGQPPFGSGNSLPAIINA
MUL_4753|M.ulcerans_Agy99 SPAFTASELARGGEPDRASDVYGVGATLFCALTGHPPFERRKGESVIAQI
: : :.* * *:*.:. : *. .
Mb3107c|M.bovis_AF2122/97 LRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQ
Rv3080c|M.tuberculosis_H37Rv LRITSQPIPDLRKQGLPADVAAAIERAMARHPADRPATAADVGEELRDVQ
MMAR_2576|M.marinum_M LRITSQPIPNLREEGLPADVASVIEKAMARDPADRPDSAAAFGEQLRQVQ
MSMEG_0529|M.smegmatis_MC2_155 LRITRHPAPNLRDADLPADLSAAIEQAMSRTISDRPESAQAFGEQLRELQ
MLBr_00016|M.leprae_Br4923 VREDPIPP-SQRHEGISVDLDAVVLKALAKNPENRYQTAAEMRADLIRVH
MAV_0017|M.avium_104 VREDPVPP-SQRHEGISADLDAVVLKALAKNPDNRYQTAAEMRADLVRVH
TH_2631|M.thermoresistible__bu VREDPVPP-SRRNPAVSPELDAVVLKALAKNPDNRYQTAAEMRADLVRVH
Mflv_1389|M.gilvum_PYR-GCK IDVPPPPL-RALSVTADPALVAVIDRAMSRDPRLRFGSAPQMRAALAGDP
Mvan_1076|M.vanbaalenii_PYR-1 LRITSQPVPDLRHLGIPSDVCSAIEKAMSLESAARFDSAAEFGRALQEAQ
MAB_4435|M.abscessus_ATCC_1997 HLSAPPPRISQLAP-VPESWDALIAKAMAKTPADRYQSAGELAMAAQQIL
MUL_4753|M.ulcerans_Agy99 LRVANDPVPDLAEYDVAEDVASVVNRALSRDPAARP-TMVELGEAIQSLQ
* : : :*:: * : .
Mb3107c|M.bovis_AF2122/97 RRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKY
Rv3080c|M.tuberculosis_H37Rv RRNGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKY
MMAR_2576|M.marinum_M REHGVAVDEMAHPVELGAPRSDLATARSTYGHD---THATPAPPTPATKY
MSMEG_0529|M.smegmatis_MC2_155 RRHGLPVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLTPPAPATRF
MLBr_00016|M.leprae_Br4923 SGQPPEAPKVLTDADR----------SCLLSSGAGNFGVPRTDALSRQSL
MAV_0017|M.avium_104 NGEKPEAPKVLTDAER----------SSLLSSGAGAAGPSRTDPLPRQVL
TH_2631|M.thermoresistible__bu SGEQPEAPKVLTDAER----------TSLLASGPAHDRTQPTDAVIDPVI
Mflv_1389|M.gilvum_PYR-GCK LALNNAPPPAPPPRAG----------TRVLAQPLPPSAGFTSAPVGYPTA
Mvan_1076|M.vanbaalenii_PYR-1 RHNGLTADTMAIGEPTPAAAP---PEGTQALPLSVPSDSVVLPPIPAAAP
MAB_4435|M.abscessus_ATCC_1997 TDPAQHRQTVTQPVPA-----------TTPAPIAAPEPVHAMAPLAMADT
MUL_4753|M.ulcerans_Agy99 AAHGQAVDAMALEGGK-------------RSTSVSSESAWHVSARQTRGN
.
Mb3107c|M.bovis_AF2122/97 RPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELS
Rv3080c|M.tuberculosis_H37Rv RPSVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELS
MMAR_2576|M.marinum_M RPQVPARSRVSRRRLTDALSAAGRRRLILIYAPSGYGKSTLAAQWREELV
MSMEG_0529|M.smegmatis_MC2_155 QMPSSAKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLAVQWAKQLA
MLBr_00016|M.leprae_Br4923 DETESD---GSIGRWVAVVAVLAVLTIAIVAAFNTFGGNTRDVQVPDVRG
MAV_0017|M.avium_104 ADSGEDRTVGSVGRWIVAVAALAVLTIIVVIAFNTFGGGARDVQVPDVRG
TH_2631|M.thermoresistible__bu PRYTGSDRGGSVGRWVAAVAVLAVLTVVVTVAINMIGGNPRNVQVPDVSG
Mflv_1389|M.gilvum_PYR-GCK APPPPTR---ARMYLMAVAAVLAFTVAALALALDPFSSPP----------
Mvan_1076|M.vanbaalenii_PYR-1 PASPPAPPPPPPPDMFARSPSNSPPITPWPVAPPPYPASVAPAKNRKKTL
MAB_4435|M.abscessus_ATCC_1997 GQSMLKHKRIAAIIGVMVLVVASSVVAVLIWPRADEGTDP----------
MUL_4753|M.ulcerans_Agy99 LPAKLAGFVGRQAELAELGALISTSRPVTLTGVGGVGKTSLAVQAAGEHV
Mb3107c|M.bovis_AF2122/97 RDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDD
Rv3080c|M.tuberculosis_H37Rv RDGAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDD
MMAR_2576|M.marinum_M RAGVAVAWLTIDDDDNNPVWFLAHLLESIRRVHPGVAESLDHVLEEHGDD
MSMEG_0529|M.smegmatis_MC2_155 ADGVAVAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGDVLEEHGDD
MLBr_00016|M.leprae_Br4923 QVSADAISALQNRG-----------FKTRTLQKPDSTIPPDHVISTEPGA
MAV_0017|M.avium_104 QVSADAIAALQNRG-----------FKTRTLQKPDSAIPPDHVIGTDPGA
TH_2631|M.thermoresistible__bu QASADAIAALQNRG-----------FKTRTQQQPDNSVPPDRVISTDPPA
Mflv_1389|M.gilvum_PYR-GCK --------PMQTVG-----------TST-TAPPPPTSVPPPTSAAPLPPP
Mvan_1076|M.vanbaalenii_PYR-1 IALAAAAAAVLLVIG---------TVVIVASRDNRSGEAGGVTTAARPTA
MAB_4435|M.abscessus_ATCC_1997 ---------------------------RTKASPSAAQVAPGASLAGQPNT
MUL_4753|M.ulcerans_Agy99 SHFHDGVWLVDIGELSDG-ALLAGLAARMLGIRDQGARPLTEVLTDALAE
Mb3107c|M.bovis_AF2122/97 AGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHL
Rv3080c|M.tuberculosis_H37Rv AGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHL
MMAR_2576|M.marinum_M GSRYLLTSIIDALHDADEPTTLIVDDWQRVSDSQTIAALSFLLEHGCHHL
MSMEG_0529|M.smegmatis_MC2_155 AERYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDNVASGL
MLBr_00016|M.leprae_Br4923 NASVGAGDEITINVSTG---------------------------------
MAV_0017|M.avium_104 NASVSAGDEITINVSTG---------------------------------
TH_2631|M.thermoresistible__bu DTSVSAGDEITVNVSTG---------------------------------
Mflv_1389|M.gilvum_PYR-GCK IVPVTQAPPPDNGPKKG---------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 EAQPGWRPIADSRIPLA---------------------------------
MAB_4435|M.abscessus_ATCC_1997 VLDTLLPGQFDYPEGWE---------------------------------
MUL_4753|M.ulcerans_Agy99 RDALVIFDGCEHVIDHA---------------------------------
Mb3107c|M.bovis_AF2122/97 QLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRL
Rv3080c|M.tuberculosis_H37Rv QLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRL
MMAR_2576|M.marinum_M QIIVTSWSRTGLPLSRLRLADELVEIDSAALRFDSGEATSFFDSLGGLSL
MSMEG_0529|M.smegmatis_MC2_155 TVVVTSRTQSGLPMSRMRMQGEIVEIDATALRFDVSESGSFLVDLAGLDL
MLBr_00016|M.leprae_Br4923 -----PEQREVPDVSSLNYTDAVKKLTSSGFKSFKQANSPSTPELLGKVI
MAV_0017|M.avium_104 -----PEQREVPDVSSLSYSDAVTKLKAAGFSKFKQANSPSTPELLGKVI
TH_2631|M.thermoresistible__bu -----PQQREIPDVSSLTYAEAVRRLSAAGFEKFRQSESPSTPELRGKVV
Mflv_1389|M.gilvum_PYR-GCK -----PDKK-----------------GEKGNNGRGNGNKPD---------
Mvan_1076|M.vanbaalenii_PYR-1 -------AAAATEADGTIWIFGGMGADNRVSGAHEGYDPAIDSWKGGEAL
MAB_4435|M.abscessus_ATCC_1997 --------------------------KNPSPTFRSGEFNPAVPPGSATNI
MUL_4753|M.ulcerans_Agy99 --------AQLIDTLLQGCPQLHILATSRELLGIGGEAVLALSPLPYPDA
Mb3107c|M.bovis_AF2122/97 PRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFL
Rv3080c|M.tuberculosis_H37Rv PRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFL
MMAR_2576|M.marinum_M TGNDVAALTESTDGWAAGLQLAGLSVRGGADASTLVGKLCGTSEVIGEFL
MSMEG_0529|M.smegmatis_MC2_155 DQTDVEELTEKTDGWVAALQLASLTLRDRDDPVQLIETMTGRHHVISEFL
MLBr_00016|M.leprae_Br4923 GTNPSANQTSAITNVITIIVGSGPETKQIPDVTGQIVEIAQKNLNVYGFT
MAV_0017|M.avium_104 GTNPPANQTSAITNVITLIVGSGPETKQVPDIAGQTVDIAQKNLTVYGFT
TH_2631|M.thermoresistible__bu ATNPPANQTAAITNEITVVVGTGPATREVPDITGQTVELAERNLSVYGFT
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 PVPVQRAMSVTWQDTPVVLGGWRSEGADTKVATDQVWRVVNSRWVQLPPL
MAB_4435|M.abscessus_ATCC_1997 GGTPVGCNTIDPAWALRAKGRETSTLYLRDRKKPEREILIRVVPAADALS
MUL_4753|M.ulcerans_Agy99 ASVSSRSSVARYDAVALFVERARTARPGFTLTQRNAAAVARICERLDGLP
Mb3107c|M.bovis_AF2122/97 SENVLDTLE-PELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHR
Rv3080c|M.tuberculosis_H37Rv SENVLDTLE-PELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHR
MMAR_2576|M.marinum_M AENVLASLE-PEIVDFVLATSIPERICADLASALAQVPRGQALLEQVAQR
MSMEG_0529|M.smegmatis_MC2_155 AENVLETLE-PSTLDFLLATSIPERICGGLASALTDVPDGQAILEKIEER
MLBr_00016|M.leprae_Br4923 KFSQASVDS-PRPTGEVIGTNPPKDATVPVDSVIELQVSKGNQFVMPDLS
MAV_0017|M.avium_104 KITQVQVDS-PRPAGEVIGTNPPKGQTVPVDSVIELQVSKGNQFIMPDLS
TH_2631|M.thermoresistible__bu KFTQSAVDS-TAPAGQVVGTNPPAGTTVSLDSVIELEVSKGNQFVMPDLI
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 LQPRAAAAA-AVVGDRIVVTGGVDAAGKVLDTTEVYDGSGWTQAAPMPTP
MAB_4435|M.abscessus_ATCC_1997 TDGASDALKRCDAVAYIIPGSSTTWRCSFEFDEPNPVQNGQKELTTTESC
MUL_4753|M.ulcerans_Agy99 LAIELAAAR-LRAVSVEQIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDW
Mb3107c|M.bovis_AF2122/97 GLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAEN
Rv3080c|M.tuberculosis_H37Rv GLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAEN
MMAR_2576|M.marinum_M GLFLQPVDGEPGWFHYHQMFAEFLRRRLERDDPQRVAQLHRTAALWLKEH
MSMEG_0529|M.smegmatis_MC2_155 DLFLRRIDDQ--WFRYHQLFRDFLRHRLSR---ERVCDLHRRACRWYAGQ
MLBr_00016|M.leprae_Br4923 GMFWADAEPRLRALGWTGVLDKGPDVDAGGSQHNRVAYQNPPAGAGVNRD
MAV_0017|M.avium_104 GMFWTDAEPRLRALGWTGILDKGPDVDAGGAQSHRVVYQNPPAGAGVNRD
TH_2631|M.thermoresistible__bu GMFWTDAEPRLRALGWTGVLDKGADIPNSGQRANAVVRQNPSPGAGVNYD
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 RQLLAAASDGELVYAIGGTNGTADLATVEAYDPAADTWTAMPALPEPRSD
MAB_4435|M.abscessus_ATCC_1997 YMFPSGANSIRQHVSFNVVRGLLVYILASGASNRNDAAGSLSATALSFAT
MUL_4753|M.ulcerans_Agy99 SYDHCTPIQQQLWARLSVFAGSFDLDAAQYVAPQDMDADDLLDELCALVD
Mb3107c|M.bovis_AF2122/97 GYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSM
Rv3080c|M.tuberculosis_H37Rv GYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSM
MMAR_2576|M.marinum_M DRLHDAVKHALAAGDPALAVDFVEDDETNLLEQSKMTTLLEIVKKLPPRL
MSMEG_0529|M.smegmatis_MC2_155 RLVREAVDHALAAGDETEAVRLVENDGLYLVSGGQMATLIGLTAKLPQDI
MLBr_00016|M.leprae_Br4923 GIITLKFGQ-----------------------------------------
MAV_0017|M.avium_104 GIITLKFGQ-----------------------------------------
TH_2631|M.thermoresistible__bu ARITLNFAS-----------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 FGVAVTDARLVAVGGTAAGRPLKTVTALDLTTSTWS--------------
MAB_4435|M.abscessus_ATCC_1997 TMKILRYGR-----------------------------------------
MUL_4753|M.ulcerans_Agy99 KSILIRTEDDGAVR--FRLLSTMREYGNSRIDAEQYQGLQQSHFDWCERL
Mb3107c|M.bovis_AF2122/97 VVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRA
Rv3080c|M.tuberculosis_H37Rv VVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRA
MMAR_2576|M.marinum_M IVSRERLQLAIAWANILLQRKVPADAALNLFTKALDHADP--ATQADLRV
MSMEG_0529|M.smegmatis_MC2_155 VRSNPRLQLALAWANIVLHRVPAARDALARVEATMADAGLSEDEIADMRA
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 -----------DLPDLGTARRGAAVAAVGKSVYVIGGSTGAGDGQATSSA
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 VTQAHLEWFSRKQVDWIHRLRSELPNIEEALQFGLEKAPESVLLMAAKLR
Mb3107c|M.bovis_AF2122/97 EADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAI
Rv3080c|M.tuberculosis_H37Rv EADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAI
MMAR_2576|M.marinum_M EADVLQAVADTFADRIDRVDTLVAEALSRPQTFHPRVPAVAGNVSAFAAL
MSMEG_0529|M.smegmatis_MC2_155 EADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFAAA
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 EALKLAPRTPQPAAQWRSLPDAPTARLMMAYTVLDDQIWIAGGIREGETL
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 NLFVVSGKLQVGRLWVERALSTTTSAQPSGARIAALAALAMFAVLQTDWP
Mb3107c|M.bovis_AF2122/97 CRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQ
Rv3080c|M.tuberculosis_H37Rv CRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQ
MMAR_2576|M.marinum_M YRFQFDQVRRLLAWATPYREMMG-PFVSVYARCYLGLAAKFALDIATALA
MSMEG_0529|M.smegmatis_MC2_155 YRYDLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVAEQ
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 DTVETYDTRTQQWQSQPS----------------LPIPLNHAVAATYRGE
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 TAQSCVAQAHEHGAAVPDPIAES------------LLGVARGLGALLQGQ
Mb3107c|M.bovis_AF2122/97 NFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLL
Rv3080c|M.tuberculosis_H37Rv NFRTAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLL
MMAR_2576|M.marinum_M EFRRAVEIAQSCG-TNSNATRIAGAFLGEMLHDVGELTEAKLLLDESYRL
MSMEG_0529|M.smegmatis_MC2_155 TLRRALRIAKRSGGIHSYAGRLASSLLGEILYEKGDLAEAERLLDEGYKL
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 VVVIGGATDTITQASDKVFAFRDGTWVELASLQHARAAPAAAVVDDKLVV
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 VEQVQTDAEQGLAAGDFELQVLGMWLMPLRHLAVGDPEPALRWAEKAHSV
Mb3107c|M.bovis_AF2122/97 GSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLA
Rv3080c|M.tuberculosis_H37Rv GSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLA
MMAR_2576|M.marinum_M GPEGGGVDYLVARFVAGARVNAAHGDCAAAAERLEAGMAVADQLHLPRLS
MSMEG_0529|M.smegmatis_MC2_155 GPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNRLQ
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 VGGQNDKQVVPQTEVFDGQSWTQAADMPTPREHLAAVSDGVYVYTVG---
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 SESRVEVQMRTYSLSALAVSHLMLGDTGSAERSLREG-------------
Mb3107c|M.bovis_AF2122/97 ARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAVR
Rv3080c|M.tuberculosis_H37Rv ARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAVR
MMAR_2576|M.marinum_M AAINHERVRLGIGLSPSVSARLRDTRHNSSD--DGIVTLTYELDEASAIR
MSMEG_0529|M.smegmatis_MC2_155 ALAEHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAIALQFEEASAIR
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 ----------GRLLSADENLAAFERFDPESGNWEKLPDMPTPRGSYGAAY
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 -------------------LKLCQVIDDPWSGASYLEGLAWTAGANGNLR
Mb3107c|M.bovis_AF2122/97 LLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGR
Rv3080c|M.tuberculosis_H37Rv LLSAGDS-ADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGR
MMAR_2576|M.marinum_M LLSAGGSEQDRADAHRRARDLLTGIDATLRPWAALRAQLLLAETLRAAGL
MSMEG_0529|M.smegmatis_MC2_155 RLMASDDPAARDLACRWAREWVDRLSALNRPQALLRARRLLGACLAADGR
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 LDGRIVVVGGEEPTRVLPTVEIYDIANRKWSTQAPVNTPVHGQAVAAVGS
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 RAVVLMAAAAALSRSSGAGSTVIALVGSMHQQCERAAREELSDAVFETAR
Mb3107c|M.bovis_AF2122/97 ESDARNELAPVATKCAELGLSRLLVDAGLA--------------------
Rv3080c|M.tuberculosis_H37Rv ESDARNELAPVATKCAELGLSRLLVDAGLA--------------------
MMAR_2576|M.marinum_M QPDP--ESAGLAQRCNELGLVRLAVDAGLT--------------------
MSMEG_0529|M.smegmatis_MC2_155 TAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELRADQEAGRWSPE
MLBr_00016|M.leprae_Br4923 --------------------------------------------------
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1076|M.vanbaalenii_PYR-1 TVYCIGGADRPTHEGPVATVEALDFT------------------------
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 VEGESLSFDDAADVALTEP-------------------------------
Mb3107c|M.bovis_AF2122/97 ---------------------
Rv3080c|M.tuberculosis_H37Rv ---------------------
MMAR_2576|M.marinum_M ---------------------
MSMEG_0529|M.smegmatis_MC2_155 WPEVPADFLQDAINSVAPQRY
MLBr_00016|M.leprae_Br4923 ---------------------
MAV_0017|M.avium_104 ---------------------
TH_2631|M.thermoresistible__bu ---------------------
Mflv_1389|M.gilvum_PYR-GCK ---------------------
Mvan_1076|M.vanbaalenii_PYR-1 ---------------------
MAB_4435|M.abscessus_ATCC_1997 ---------------------
MUL_4753|M.ulcerans_Agy99 ---------------------