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VSQLIGQLGADGFADAVEVGRGGFGVVYRARQVELDRVVAVKVLTADLEQNRPRFEREQRAMARLTGHPN IVSVLQVGHTPGGYPYLVMPFCSRGSVQEVITECGGLAVSEVLRLGVAVAAGLESAHRLGIVHRDVKPAN VLLTELGDPAVTDFGIAHMVGGFHTASGVFSATPDFTAPEVLSGKEPDQASDVYGLGATLFCALTGQPPF ARRDGEVLMAQLLRIATKSAPDLRAYGVDDDLAVVIGAALAPEPTARPAMVEFGEALQELQATRGLAIDA MALQGAKHTGKTAAARPVPPPRVRGNLPAPLSEFVGRAAELAALAELFSTARLVTLVGVGGVGKTTLALR AARTRAADYPAGVWVIDIGELRDGALLPGLAAGALGIHDQGSRALPEVMVDAIGEREMLLVFDNCEHVID EAAALIDTLLRGCPRLQIVATSRELLSLDGEAVFAVSPLRYPDTTTGTSRAALADYDAVALFVERAQAAR PGFTLTEHNAGAIALICSRLDGVPLAVELAAARVRAMSVQQIAARLSESFALLSRGYRGSPTHQQTLRCC IDWSYQRCSTAEQQLWARLSVFAGSFDLDLAHHVCAPDTCPDDLLDQLCELVDKSILSRIDNNDDAEVRF RLLATPREYGASCLTAADHQLLRQRHLDGYRQLVAKAHAEWFSEHQVNWIRRMRRELPNVQEALQFGLTH APDTALEMVADLRMLFIVSGKLKEGRRWLDRALSATPESSTKNRIRGLTTGVGFAYFQMDWPAVTQWLAE ARNLLELEPYPEMDGLLCGYDGFSTLLRGEIDQARVSAERGLAITGDYDDYQVRIGCMWVMSFHSALVGD ADQALHWAERAYALAESRHEVQMRTFTVSALVVGWLTRGGVEHADSALRKALELCRASDYPFAGAQCLEG MAWTSAANNNLRRAVVLMTAAATISQITTGSSTTFFAAMGPFHADCERRARAELSETEFESARIQGESLT FDEAVAFALGHEW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4754 | pknK_2 | - | 100% (994) | serine/threonine-protein kinase transcriptional regulatory protein PknK_2 |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | 0.0 | 59.27% (982) | serine/threonine-protein kinase transcriptional regulatory |
| M. ulcerans Agy99 | MUL_2743 | - | 2e-65 | 32.82% (655) | LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 3e-86 | 38.53% (571) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_1389 | - | 6e-32 | 36.39% (294) | protein kinase |
| M. tuberculosis H37Rv | Rv3080c | pknK | 9e-87 | 38.70% (571) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_01753 | - | 4e-66 | 31.65% (613) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4435 | - | 4e-31 | 33.93% (333) | serine/threonine-protein kinase PknJ |
| M. marinum M | MMAR_0365 | pknK_2 | 0.0 | 99.40% (994) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_0017 | - | 5e-31 | 36.69% (248) | serine/threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 6e-79 | 39.82% (545) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2631 | - | 8e-30 | 35.63% (247) | PUTATIVE serine/threonine protein kinase |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 3e-79 | 33.33% (651) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4754|M.ulcerans_Agy99 -----------------------------------------MVSQLIGQL
MMAR_0365|M.marinum_M -----------------------------------------MVSQLIGQL
MAV_0017|M.avium_104 --------------------------------------------MTTPQH
TH_2631|M.thermoresistible__bu --------------------------------------------MTTPQH
Mflv_1389|M.gilvum_PYR-GCK ---------------------------------------------MTAEM
Mb3107c|M.bovis_AF2122/97 -----------------------------MTDVDPHATRRDLVPNIPAEL
Rv3080c|M.tuberculosis_H37Rv -----------------------------MTDVDPHATRRDLVPNIPAEL
MSMEG_0529|M.smegmatis_MC2_155 -----------------------------MVRNDPLPTQRDLPAGIPAEL
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
Mvan_5928|M.vanbaalenii_PYR-1 ------MSELVPTG-------------------------TVTLLLADVQG
MAB_4435|M.abscessus_ATCC_1997 ---------------------------MTSSDRSSPGPGGQQPGDLPPGT
MUL_4754|M.ulcerans_Agy99 GADGFADAVEVGRGGFGVVYRARQVELDRVVAVKVLTADLEQNR---PRF
MMAR_0365|M.marinum_M GADGFADAVEVGRGGFGVVYRARQVELDRVVAVKVLTADLEQNR---PRF
MAV_0017|M.avium_104 LSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRF
TH_2631|M.thermoresistible__bu LSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRF
Mflv_1389|M.gilvum_PYR-GCK LAGRYELRGLLGRGGMAEVRDGWDTRLDRSVAVKLLYPSQSSDDSVRRRF
Mb3107c|M.bovis_AF2122/97 LEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN--LERF
Rv3080c|M.tuberculosis_H37Rv LEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN--LERF
MSMEG_0529|M.smegmatis_MC2_155 VAAGFEDPDEIGRGGFGVVYRCVQRALDRTVAVKVLTTDLEPDN--LERF
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
Mvan_5928|M.vanbaalenii_PYR-1 STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR
MAB_4435|M.abscessus_ATCC_1997 VVSGYQIERVLGRGGMGTVYLAANPNLQRSEALKILSAQSSRDPEFRARF
... : : .:: : .
MUL_4754|M.ulcerans_Agy99 EREQRAMARLTGHPNIVSV-----LQVGHTPGG---YPYLVMPFCSRGSV
MMAR_0365|M.marinum_M EREQRAMARLTGHPNIVSV-----LQVGHTPGG---YPYLVMPFCSRGSV
MAV_0017|M.avium_104 RREAQNAAALN-HPSIVAV-----YDTGEAETPSGPLPYIVMEYVDGVTL
TH_2631|M.thermoresistible__bu RREAQNAAALN-HPAIVAV-----YDTGEAETPTGPLPYIVMEYVDGVTL
Mflv_1389|M.gilvum_PYR-GCK EDEARSAARLS-HPNIVAI-----HDFGEHDS----APFIVMERLPGRTL
Mb3107c|M.bovis_AF2122/97 LREQRAMGRLSGHPHIVTV-----LQVGVLAGG---RPFIVMPYHAKNSL
Rv3080c|M.tuberculosis_H37Rv LREQRAMGRLSGHPHIVTV-----LQVGVLAGG---RPFIVMPYHAKNSL
MSMEG_0529|M.smegmatis_MC2_155 MREQVAMGKLSGHPNIVNI-----FQVGTIASG---RPYIVMQYHPHGSL
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
Mvan_5928|M.vanbaalenii_PYR-1 ASDAVACALALQRAPLAPIRLRIGVHTGEVRLR-DEGNYVGPTINRTARL
MAB_4435|M.abscessus_ATCC_1997 MREASLAASLD-HPNIVTV-----HNRGETPEG---DLWIAMQYVQG-SD
: . . :. : . * :
MUL_4754|M.ulcerans_Agy99 QEVITECGGLAVSEVLRLGVAVAAGLESAHRLG-IVHRDVKPAN--VLLT
MMAR_0365|M.marinum_M QEVITECGGLAVSEVLRLGVAVAAGLESAHRLG-IVHRDVKPAN--VLLT
MAV_0017|M.avium_104 RDIVHTDGPLPPRRAIEIIADACQALNFSHQNG-IIHRDVKPAN--IMIS
TH_2631|M.thermoresistible__bu RDIVHTDGPMEPKRAIEVIADACQALNFSHQHG-IIHRDVKPAN--IMIS
Mflv_1389|M.gilvum_PYR-GCK ADVIE-QGPMPAPQVRRVLDEVLAALSVAHAAG-VLHRDIKPAN--ILLT
Mb3107c|M.bovis_AF2122/97 ETLIRRHGPLDWRETLSIGVKLAGALEAAHRVG-TLHRDVKPGN--ILLT
Rv3080c|M.tuberculosis_H37Rv ETLIRRHGPLDWRETLSIGVKLAGALEAAHRVG-TLHRDVKPGN--ILLT
MSMEG_0529|M.smegmatis_MC2_155 SAKIQAAGPLGWRGALRIGVKMAGALETAHQRD-TLHRDVKPAN--ILLT
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
Mvan_5928|M.vanbaalenii_PYR-1 RELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQLC
MAB_4435|M.abscessus_ATCC_1997 AHSESASGRMSLTRAVHIISEVAKALDYLHARG-LVHRDVKPAN--ILLS
: . : . **: : :
MUL_4754|M.ulcerans_Agy99 ELG-DPAVTDFGIAHMVGGF---HTASGVFSATPDFTAPEVLSGKE-PDQ
MMAR_0365|M.marinum_M EFG-DPALTDFGIAHMVGGF---HTASGVFSATPDFTAPEVLSGKE-PDQ
MAV_0017|M.avium_104 TTN-AVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDA-VDA
TH_2631|M.thermoresistible__bu KTG-AVKVMDFGIARAIADS-NSVTQTAAVIGTAQYLSPEQARGET-VDA
Mflv_1389|M.gilvum_PYR-GCK TAGDSVKVADFGIAKSAGAA---HTATGQIVGTLCYLSPERVMGAP-ASV
Mb3107c|M.bovis_AF2122/97 DYG-EPQLTDFGIARIAGGF---ETATGVIAGSPAFTAPEVLEGAS-PTP
Rv3080c|M.tuberculosis_H37Rv DYG-EPQLTDFGIARIAGGF---ETATGVIAGSPAFTAPEVLEGAS-PTP
MSMEG_0529|M.smegmatis_MC2_155 EYG-EPQLTDFGIARIAGGF---ETAEGAIMGSPAYTAPEVLLGES-PTV
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
Mvan_5928|M.vanbaalenii_PYR-1 HADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANRLVT
MAB_4435|M.abscessus_ATCC_1997 AGDRRIMLGDFGLTRALDDS-NSVTSAGNVTATIAYAAPEILSGTA-VDG
. . : . .
MUL_4754|M.ulcerans_Agy99 ASDVYGLGATLFCALTGQPPFARRDGEVLMAQLLRIATKSAPDLRAY---
MMAR_0365|M.marinum_M ASDVYGLGATLFCALTGQPPFARRDGEVLMAQLLRIATESAPDLRAY---
MAV_0017|M.avium_104 RSDVYSLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPVPP-SQRHE---
TH_2631|M.thermoresistible__bu RSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPP-SRRNP---
Mflv_1389|M.gilvum_PYR-GCK ADDLYAVGVMGYEALLGRRAFPQDNPAALARAIIDVPPPPL-RALSV---
Mb3107c|M.bovis_AF2122/97 ASDVYSLGATLFCVLTGHAAYERRSGERVIAQFLRITSQPIPDLRKQ---
Rv3080c|M.tuberculosis_H37Rv ASDVYSLGATLFCALTGHAAYERRSGERVIAQFLRITSQPIPDLRKQ---
MSMEG_0529|M.smegmatis_MC2_155 ASDVYSLASTVFTASTGHAVFERGKGEQMVAQFLRITRHPAPNLRDA---
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVL---
Mvan_5928|M.vanbaalenii_PYR-1 LTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAITVARAL
MAB_4435|M.abscessus_ATCC_1997 RADVYALGCTLFRMLTGQPPFGSGNSLPAIINAHLSAPPPRISQLAP---
. .:.
MUL_4754|M.ulcerans_Agy99 ------------GVDDDLAVVIGAALAPEPTARP-AMVEFGEALQELQAT
MMAR_0365|M.marinum_M ------------GVDDDLAVVIGAALAPEPTARP-AMVEFGEALQELQAT
MAV_0017|M.avium_104 ------------GISADLDAVVLKALAKNPDNRYQTAAEMRADLVRVHN-
TH_2631|M.thermoresistible__bu ------------AVSPELDAVVLKALAKNPDNRYQTAAEMRADLVRVHS-
Mflv_1389|M.gilvum_PYR-GCK ------------TADPALVAVIDRAMSRDPRLRFGSAPQMRAALAGDPL-
Mb3107c|M.bovis_AF2122/97 ------------GLPADVAAAIERAMARHPADRPATAADVGEELRDVQRR
Rv3080c|M.tuberculosis_H37Rv ------------GLPADVAAAIERAMARHPADRPATAADVGEELRDVQRR
MSMEG_0529|M.smegmatis_MC2_155 ------------DLPADLSAAIEQAMSRTISDRPESAQAFGEQLRELQRR
MLBr_01753|M.leprae_Br4923 -----------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPS
Mvan_5928|M.vanbaalenii_PYR-1 GLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATLIDALLGACPA
MAB_4435|M.abscessus_ATCC_1997 -------------VPESWDALIAKAMAKTPADRYQSAGELAMAAQQILTD
: .
MUL_4754|M.ulcerans_Agy99 RGLAIDAMALQG----------------AKHTGKTAAARPVPPPRVRGNL
MMAR_0365|M.marinum_M RGLAIDAMALQG----------------AKHTGKTAAARPVPPPRVRGNL
MAV_0017|M.avium_104 --------------------------------GEKPEAPKVLTDAE----
TH_2631|M.thermoresistible__bu --------------------------------GEQPEAPKVLTDAE----
Mflv_1389|M.gilvum_PYR-GCK --------------------------------ALNNAPPPAPPPRA----
Mb3107c|M.bovis_AF2122/97 NGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRP
Rv3080c|M.tuberculosis_H37Rv NGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRP
MSMEG_0529|M.smegmatis_MC2_155 HGLPVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLTPPAPATRFQM
MLBr_01753|M.leprae_Br4923 LTILATSREPIGVAGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDG
Mvan_5928|M.vanbaalenii_PYR-1 LAMLATSREPIAVAGEQTWRVPPLALDDDAIELFTDRARRARPDFIISAD
MAB_4435|M.abscessus_ATCC_1997 P-------------------------------AQHRQTVTQP--------
MUL_4754|M.ulcerans_Agy99 PAPLSEFVGR-----------------AAELAALAELFSTARLVTLVGVG
MMAR_0365|M.marinum_M PAPLSEFVGR-----------------AAELAALAELFSTARLVTLVGVG
MAV_0017|M.avium_104 ----------------------------------RSSLLSSGAGAAGPSR
TH_2631|M.thermoresistible__bu ----------------------------------RTSLLASGPAHDRTQP
Mflv_1389|M.gilvum_PYR-GCK ----------------------------------GTRVLAQPLPPSAGFT
Mb3107c|M.bovis_AF2122/97 SVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRD
Rv3080c|M.tuberculosis_H37Rv SVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRD
MSMEG_0529|M.smegmatis_MC2_155 PSSAKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLAVQWAKQLAAD
MLBr_01753|M.leprae_Br4923 NRQIVTEICQRLDG--------------MPLAIELAAARIRTLSLTEIAD
Mvan_5928|M.vanbaalenii_PYR-1 DAAAVSEICHRLDG--------------MPLAIELAAARVRALSLTEIVD
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------VPATTPAPIAAP
MUL_4754|M.ulcerans_Agy99 GVGKTTLALRAARTRAADYPAGVWVIDIGELRDGALLPGLAAGALGIHDQ
MMAR_0365|M.marinum_M GVGKTTLALRAARTRAADYPAGVWVIDIGELRDGALLPGLAAGALGIHDQ
MAV_0017|M.avium_104 TDPLPRQVLADSGEDRTVGSVGRWIVAVAALAVLTIIVVIAFNTFGGGAR
TH_2631|M.thermoresistible__bu TDAVIDPVIPRYTGSDRGGSVGRWVAAVAVLAVLTVVVTVAINMIGGNPR
Mflv_1389|M.gilvum_PYR-GCK SAPVGYPTAAPPPPTR---ARMYLMAVAAVLAFTVAALALALDPFSSPP-
Mb3107c|M.bovis_AF2122/97 GAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAG
Rv3080c|M.tuberculosis_H37Rv GAAVAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAG
MSMEG_0529|M.smegmatis_MC2_155 GVAVAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGDVLEEHGDDAE
MLBr_01753|M.leprae_Br4923 GLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISG
Mvan_5928|M.vanbaalenii_PYR-1 GLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAVFAG
MAB_4435|M.abscessus_ATCC_1997 EPVHAMAPLAMADTGQSMLKHKRIAAIIGVMVLVVASSVVAVLIWPRADE
.
MUL_4754|M.ulcerans_Agy99 GSRALPEVMVDAIGEREMLLVFDNCEHVIDEAAALIDTLLRGCPRLQIVA
MMAR_0365|M.marinum_M GSRALPEVMVDAIGEREMLLVFDNCEHVIDEAAALIDTLLRGCPRLQIVA
MAV_0017|M.avium_104 DVQVPDVRGQVSADAIAALQNRGFKTRTLQKPDSAIPPDHVIGTDPGANA
TH_2631|M.thermoresistible__bu NVQVPDVSGQASADAIAALQNRGFKTRTQQQPDNSVPPDRVISTDPPADT
Mflv_1389|M.gilvum_PYR-GCK -----------------PMQTVGTSTTAPPPPTSVPPP------------
Mb3107c|M.bovis_AF2122/97 RYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQL
Rv3080c|M.tuberculosis_H37Rv RYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQL
MSMEG_0529|M.smegmatis_MC2_155 RYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDNVASGLTV
MLBr_01753|M.leprae_Br4923 TFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKS-LVIVEGRQGGSRYRLLE
Mvan_5928|M.vanbaalenii_PYR-1 GFDLDGAQAITVDGEVHRYEVVDLLTLLVDKS-LLIAENTAGRTRYRLLE
MAB_4435|M.abscessus_ATCC_1997 GTDPRTKASPSAAQVAPGASLAGQPNTVLDTLLPGQFDYPEGWEKNPSPT
.
MUL_4754|M.ulcerans_Agy99 TSRELLSLDGEAVFAVSPLRYPDTTTGTSRAALADYDAVALFVERAQAAR
MMAR_0365|M.marinum_M TSRELLSLDGEAVFAVSPLRYPDTTTGTSRAALADYDAVALFVERAQAAR
MAV_0017|M.avium_104 SVSAGDEITINVSTGPEQREVPDVSSLSY----SDAVTKLKAAGFSKFKQ
TH_2631|M.thermoresistible__bu SVSAGDEITVNVSTGPQQREIPDVSSLTY----AEAVRRLSAAGFEKFRQ
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 IVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPR
Rv3080c|M.tuberculosis_H37Rv IVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPR
MSMEG_0529|M.smegmatis_MC2_155 VVTSRTQSGLPMSRMRMQGEIVEIDATALRFDVSESGSFLVDLAGLDLDQ
MLBr_01753|M.leprae_Br4923 TVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQVE
Mvan_5928|M.vanbaalenii_PYR-1 TVRQYAQEKLGESGEADTLRARHRDHYTARAAELDAPSVAGHERRLNQTD
MAB_4435|M.abscessus_ATCC_1997 FRSGEFNPAVPPG-----------------------------------SA
MUL_4754|M.ulcerans_Agy99 PGFTLTEHNAG---------------------------AIALICSRLDGV
MMAR_0365|M.marinum_M PGFTLTEHNAG---------------------------AIALICSRLDGV
MAV_0017|M.avium_104 ANSPSTPELLG---------------------------------------
TH_2631|M.thermoresistible__bu SESPSTPELRG---------------------------------------
Mflv_1389|M.gilvum_PYR-GCK TSAAPLPPPIV---------------------------------------
Mb3107c|M.bovis_AF2122/97 ADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSE
Rv3080c|M.tuberculosis_H37Rv ADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSE
MSMEG_0529|M.smegmatis_MC2_155 TDVEELTEKTDGWVAALQLASLTLRDRDDPVQLIETMTGRHHVISEFLAE
MLBr_01753|M.leprae_Br4923 TELDNLRSAFAWS---------------------------RETGDIAGAL
Mvan_5928|M.vanbaalenii_PYR-1 IEMDNLRAAFAWS---------------------------RENANTDHSL
MAB_4435|M.abscessus_ATCC_1997 TNIGGTPVG-----------------------------------------
MUL_4754|M.ulcerans_Agy99 PLAVELAAARVRAMSVQQIAARLSESFALLSRGYRGS-------------
MMAR_0365|M.marinum_M PLAVELAAARVRAMSVQQIAARLSESFALLSRGYRGS-------------
MAV_0017|M.avium_104 KVIGTNPPANQTSAITNVITLIVGSGPETKQVPDIAG-------------
TH_2631|M.thermoresistible__bu KVVATNPPANQTAAITNEITVVVGTGPATREVPDITG-------------
Mflv_1389|M.gilvum_PYR-GCK PVTQAPPPDNGPKKGPDKKGEKGNNGRGNGNKPD----------------
Mb3107c|M.bovis_AF2122/97 NVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHRGLF
Rv3080c|M.tuberculosis_H37Rv NVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHRGLF
MSMEG_0529|M.smegmatis_MC2_155 NVLETLEPSTLDFLLATSIPERICGGLASALTDVPDGQAILEKIEERDLF
MLBr_01753|M.leprae_Br4923 QLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPK-----------
Mvan_5928|M.vanbaalenii_PYR-1 LLASSLHPLWRARGRLQEGQAWFDAALTDYEARPGEADP-----------
MAB_4435|M.abscessus_ATCC_1997 --CNTIDPAWALRAKGRETSTLYLRDRKKPEREILIR-------------
.
MUL_4754|M.ulcerans_Agy99 -------------------------------PTHQQTLRCCIDWSYQRCS
MMAR_0365|M.marinum_M -------------------------------PTHQQTLRCCIDWSYQRCS
MAV_0017|M.avium_104 -------------------------------QTVDIAQKNLTVYGFTKIT
TH_2631|M.thermoresistible__bu -------------------------------QTVELAERNLSVYGFTKFT
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAENGYL
Rv3080c|M.tuberculosis_H37Rv LQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAENGYL
MSMEG_0529|M.smegmatis_MC2_155 LRRIDD--QWFRYHQLFRDFLRHRLSR---ERVCDLHRRACRWYAGQRLV
MLBr_01753|M.leprae_Br4923 -----------------------------EVLARAVANKVMLHAILASSP
Mvan_5928|M.vanbaalenii_PYR-1 -----------------------------AVYARALADRAFMDGHVG---
MAB_4435|M.abscessus_ATCC_1997 --------------------------------VVPAADALSTDGASDALK
MUL_4754|M.ulcerans_Agy99 TAEQQLWARLSVFAGSFDLDLAHHVCAPDTCPDDLLDQLCELVDKSILSR
MMAR_0365|M.marinum_M TAEQQLWARLSVFAGSFDLDLAHHVCAPDTCPDDLLDQLCELVDKSILSR
MAV_0017|M.avium_104 QVQVDSPRPAGEVIGTNPPKGQT---------------VPVDSVIELQVS
TH_2631|M.thermoresistible__bu QSAVDSTAPAGQVVGTNPPAGTT---------------VSLDSVIELEVS
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 HEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVS
Rv3080c|M.tuberculosis_H37Rv HEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVS
MSMEG_0529|M.smegmatis_MC2_155 REAVDHALAAGDETEAVRLVENDGLYLVSGGQMATLIGLTAKLPQDIVRS
MLBr_01753|M.leprae_Br4923 PDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAE
Mvan_5928|M.vanbaalenii_PYR-1 --ITDRLDQAQKALAMARDIDDPALLVRALTACGGLAAYNADVARPLLAE
MAB_4435|M.abscessus_ATCC_1997 RCDAVAYIIPGSSTTWR---------------------CSFEFDEPNPVQ
MUL_4754|M.ulcerans_Agy99 IDNNDDAEVRFRLLATPREYGAS--CLTAADHQLLRQRHLDG--YRQLVA
MMAR_0365|M.marinum_M IDNNDDAEVRFRLLATLREYGAS--CLTAADHQLLRQRHLDG--YRQLVA
MAV_0017|M.avium_104 KGNQFIMPDLSGMFWTDAEPRLR--ALGWTGILDKGPDVDAGGAQSHRVV
TH_2631|M.thermoresistible__bu KGNQFVMPDLIGMFWTDAEPRLR--ALGWTGVLDKGADIPNSGQRANAVV
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RARLQLAIAWANILLQRPAPATG--ALNRFETALGRAELPEATQADLRAE
Rv3080c|M.tuberculosis_H37Rv RARLQLAIAWANILLQRPAPATG--ALNRFETALGRAELPEATQADLRAE
MSMEG_0529|M.smegmatis_MC2_155 NPRLQLALAWANIVLHRVPAARD--ALARVEATMADAGLSEDEIADMRAE
MLBr_01753|M.leprae_Br4923 AVELARTQGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAADDLAQEIG
Mvan_5928|M.vanbaalenii_PYR-1 AVDLARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADEMG
MAB_4435|M.abscessus_ATCC_1997 NGQKELTTTESCYMFPSGANSIR-QHVSFNVVRGLLVYILASGASNRNDA
MUL_4754|M.ulcerans_Agy99 KAHAEWFSEHQVNWIRRMRRELPNVQEALQFGLTHAPDTALEMVADLRML
MMAR_0365|M.marinum_M KAHAEWFSEHQVNWIRRMRRELPNVQEALQFGLTHAPDTALEMVADLRML
MAV_0017|M.avium_104 YQNPPAGAGVNRDGIITLKFGQ----------------------------
TH_2631|M.thermoresistible__bu RQNPSPGAGVNYDARITLNFAS----------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAIC
Rv3080c|M.tuberculosis_H37Rv ADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAIC
MSMEG_0529|M.smegmatis_MC2_155 ADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFAAAY
MLBr_01753|M.leprae_Br4923 DRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLY
Mvan_5928|M.vanbaalenii_PYR-1 DGFVSRICGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCGEL
MAB_4435|M.abscessus_ATCC_1997 AGSLSATALSFATTMKILRYGR----------------------------
MUL_4754|M.ulcerans_Agy99 FIVSGKLKEGRRWLDRALSATPESSTKNRIRGLTTGVGFAYFQMDWPAVT
MMAR_0365|M.marinum_M FIVSGKLKEGRRWLDRALSATPESSTKNRIRGLTTGVGFAYFQMDWPAVT
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQN
Rv3080c|M.tuberculosis_H37Rv RFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQN
MSMEG_0529|M.smegmatis_MC2_155 RYDLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVAEQT
MLBr_01753|M.leprae_Br4923 VQTRALVHR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGD
Mvan_5928|M.vanbaalenii_PYR-1 VLAHSLAQRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGD
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 QWLAEARNLLELEPYPEMDGLLCG---YDGFSTLLRGEIDQARVSAERGL
MMAR_0365|M.marinum_M QWLAEARNLLELEPYPEMDGLLCG---YDGFSTLLRGEIDQARVSAERGL
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 FRTAFEVGTAVG-AHSHAARLAGS---LLAELLYETGDLAGAGRLMDESY
Rv3080c|M.tuberculosis_H37Rv FRTAFEVGTAVG-AHSHAARLAGS---LLAELLYETGDLAGAGRLMDESY
MSMEG_0529|M.smegmatis_MC2_155 LRRALRIAKRSGGIHSYAGRLASS---LLGEILYEKGDLAEAERLLDEGY
MLBr_01753|M.leprae_Br4923 VAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADNSV
Mvan_5928|M.vanbaalenii_PYR-1 VTAAEAASDSATRSFGPSEVAGIQDPNVAAQIACTRGDLDTARSLVDGAV
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 AITGDYDDYQVRIGCMWVMSFHSALVGDADQALHWAERAYALAESRHEVQ
MMAR_0365|M.marinum_M AITGDYDDYQVRIGCMWVMSFHSALVGDADQALHWAERAYALAESRHEVQ
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPR
Rv3080c|M.tuberculosis_H37Rv LLGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPR
MSMEG_0529|M.smegmatis_MC2_155 KLGPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNR
MLBr_01753|M.leprae_Br4923 SATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISD
Mvan_5928|M.vanbaalenii_PYR-1 SITRGVHRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPD
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 ---------MRTFTVSALVVGWLTRGGVEHADSALR--------KALELC
MMAR_0365|M.marinum_M ---------MRTFTVSALVVGWLTRGDVEHADSALR--------KALELC
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ---------LAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATM
Rv3080c|M.tuberculosis_H37Rv ---------LAARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATM
MSMEG_0529|M.smegmatis_MC2_155 ---------LQALAEHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAI
MLBr_01753|M.leprae_Br4923 SMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAV
Mvan_5928|M.vanbaalenii_PYR-1 TLECLARVVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTT
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 RASDYPFAGAQCLEGMAWTSAANNNLRRAVVLMTAAATISQITTGSSTTF
MMAR_0365|M.marinum_M RASDYPFAGAQCLEGMAWTSAANNNLRRAVVLMTAAATISQITTGSSTTF
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TAELDEDSAVR-LLSAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQI
Rv3080c|M.tuberculosis_H37Rv TAELDEDSAVR-LLSAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQI
MSMEG_0529|M.smegmatis_MC2_155 ALQFEEASAIRRLMASDDPAARDLACRWAREWVDRLSALNRPQALLRARR
MLBr_01753|M.leprae_Br4923 LRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAE
Mvan_5928|M.vanbaalenii_PYR-1 LRDALGDKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTE
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 FAAMGPFHADCERRARAELSETEFESARIQGESLTFDEAVAFALGHEW--
MMAR_0365|M.marinum_M FAVMGPFHADCERRARAELSETEFESARIQGESLTFDEAVAFALGHEW--
MAV_0017|M.avium_104 --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA---------
Rv3080c|M.tuberculosis_H37Rv LHIETLAATGRESDARNELAPVATKCAELGLSRLLVDAGLA---------
MSMEG_0529|M.smegmatis_MC2_155 LLGACLAADGRTAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELR
MLBr_01753|M.leprae_Br4923 HNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEA
Mvan_5928|M.vanbaalenii_PYR-1 LDVVGLVSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEA
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4754|M.ulcerans_Agy99 --------------------------------
MMAR_0365|M.marinum_M --------------------------------
MAV_0017|M.avium_104 --------------------------------
TH_2631|M.thermoresistible__bu --------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------
Mb3107c|M.bovis_AF2122/97 --------------------------------
Rv3080c|M.tuberculosis_H37Rv --------------------------------
MSMEG_0529|M.smegmatis_MC2_155 ADQEAGRWSPEWPEVPADFLQDAINSVAPQRY
MLBr_01753|M.leprae_Br4923 ARHN----------------------------
Mvan_5928|M.vanbaalenii_PYR-1 ARHT----------------------------
MAB_4435|M.abscessus_ATCC_1997 --------------------------------