For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PVPPSEGIAARSLLRDNAYKALRTAIVDGTLAPGERLRDDELSRWLGVSRTPIREALARLEQAGLVQTQP GRHTIVSPIDVREARAAQSVAAAMHELAVREAITNISPGDLAAMRHANTRFAAALDAHDPDAALAADDEF HAVAVEASANPYIAAVLEQVTPVLRRLERIRFASRDGRHSVALHEQIIARCEAGDSEGAGRAARDNWHTL IAAPEGAAHEERGAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1705c | - | - | 100% (226) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0068 | - | 1e-14 | 31.96% (194) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4571 | - | 4e-14 | 34.03% (191) | GntR family transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 7e-13 | 29.08% (196) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4366 | - | 3e-18 | 31.90% (210) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 5e-12 | 26.96% (204) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0408 | - | 3e-17 | 35.60% (191) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1576 | - | 2e-16 | 33.12% (154) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_6738 | - | 2e-64 | 57.21% (222) | transcriptional regulator YdhC |
| M. thermoresistible (build 8) | TH_3342 | - | 3e-18 | 33.33% (201) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3894 | - | 2e-17 | 35.71% (154) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1978 | - | 9e-20 | 31.50% (200) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1576|M.avium_104 -----------------------------------------MSVPDFA--
MUL_3894|M.ulcerans_Agy99 -----------------------------------------MTDPEFA--
TH_3342|M.thermoresistible__bu -----------------------------------------VAVPEFA--
Mflv_4366|M.gilvum_PYR-GCK -----------------------------------------MTTPEFA--
Mvan_1978|M.vanbaalenii_PYR-1 -----------------------------------------MSIPEFA--
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR
MAB_1705c|M.abscessus_ATCC_199 -----------------------------------------MPVPPSEGI
MSMEG_6738|M.smegmatis_MC2_155 -----------------------------------------MPVPIERGK
: *
MAV_1576|M.avium_104 ------ARPQLSDDVAHLIRGRIFDGSYAAGSYVRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99 ------ARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
TH_3342|M.thermoresistible__bu ------ARPQLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVTPV
Mflv_4366|M.gilvum_PYR-GCK ------ARPQLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
Mvan_1978|M.vanbaalenii_PYR-1 ------ARPQLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVTPV
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MMAR_0408|M.marinum_M KSRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
MAB_1705c|M.abscessus_ATCC_199 -----AARSLLRDNAYKALRTAIVDGTLAPGERLRDDELSRWLGVSRTPI
MSMEG_6738|M.smegmatis_MC2_155 -----HRRSLLRDQAYVSIRDAIVNGTLAPGEKLRDPELEEWLGISRTPI
*. * ::. :* * .* .* :* : **:* **:
MAV_1576|M.avium_104 REALFALRAEGLISQQPRRGFVVLPVTRRDVTDVANVQAHVGGELAARAA
MUL_3894|M.ulcerans_Agy99 REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
TH_3342|M.thermoresistible__bu REALFQLRAEGLLVQQPRRGFMVLPVTERDLTDIANVQAHVGGELAARAA
Mflv_4366|M.gilvum_PYR-GCK REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
Mvan_1978|M.vanbaalenii_PYR-1 REALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASRAA
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MMAR_0408|M.marinum_M REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
MAB_1705c|M.abscessus_ATCC_199 REALARLEQAGLVQTQPGRHTIVSPIDVREARAAQSVAAAMHELAVREAI
MSMEG_6738|M.smegmatis_MC2_155 REALARLETAGLVHTTPGRSTVVAAIEPQAVLNAQSVAAAMHALAVRTAV
**** *. *:: * * :* .: : : * : . *
MAV_1576|M.avium_104 VNITDDQLRELKQIQAQLEDAYAGDEHERTVRLNHEFHRAINIAADSPKL
MUL_3894|M.ulcerans_Agy99 INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
TH_3342|M.thermoresistible__bu QNITDEQLRVLTAIQDELEEAYTRDDEDRAVRLNHEFHRAINVAADSPKL
Mflv_4366|M.gilvum_PYR-GCK ELITDEQLAELERIQDELEAAYDAVDHEAAVRLNHAFHRGVNIAAGSPKL
Mvan_1978|M.vanbaalenii_PYR-1 ERITDEQLQALDHVQDQLEVAYHADDHEAAVRLNHEFHRGVNVAAGSPKL
Mb0170c|M.bovis_AF2122/97 AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
Rv0165c|M.tuberculosis_H37Rv AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
MMAR_0408|M.marinum_M ERISEIDIGELEHINDALTAAVGAGDTEAIAALEFAFHRVLNQSSGRIKL
MAB_1705c|M.abscessus_ATCC_199 TNISPGDLAAMRHANTRFAAALDAHDPDAALAADDEFHAVAVEASANPYI
MSMEG_6738|M.smegmatis_MC2_155 PLMDKSDFDAMTAANHAFAQAISRGDPEAAMRSDDHFHGVAVQASGNEVI
: :: : : : * : . : ** :: :
MAV_1576|M.avium_104 AQLMSQITRYAPESVFPAIQGW-PEQSMKDHRRILSALKKRDDKLARAAM
MUL_3894|M.ulcerans_Agy99 SQLMSQITRYQPESVFPGIEHW-PARAVKDHGQVLVALKKHDDKAARTAM
TH_3342|M.thermoresistible__bu AQVMSQITRYAPESVFPTISGW-PARSTEHHRRVLAALADRDPDGARAAM
Mflv_4366|M.gilvum_PYR-GCK AQLMGQITRFALESVYPTVEGW-PAHSMNDHRVLLAALRKRDGTAARDAM
Mvan_1978|M.vanbaalenii_PYR-1 AQLMGQITKFALESVYPTVEGW-PAHSTRDHRELLAALKARDSEAARAAM
Mb0170c|M.bovis_AF2122/97 AWFLLNAARYMPAQVFAADPRW-GADAVNSHRQLIAALRRRDTAAVIEHT
Rv0165c|M.tuberculosis_H37Rv AWFLLNAARYMGAGVRGRP-----AMGRGRGEQSSAADRR---AAPPRHS
MMAR_0408|M.marinum_M AWFLLNAARYMPAQLYASDPQW-GAAAVDNHRQLIAALRRRDTAAVIEHS
MAB_1705c|M.abscessus_ATCC_199 AAVLEQVTPVLRRLERIRFASRDGRHSVALHEQIIARCEAGDSEGAGRAA
MSMEG_6738|M.smegmatis_MC2_155 EQVLEQVTPVLRRLEYLRFSALSGRESIEQHRRIVSLCRKRDAEGAAAAT
.: : : .
MAV_1576|M.avium_104 SEHLAAGAVPLIDHLVARGVVVD----GGGPDPG---
MUL_3894|M.ulcerans_Agy99 SEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
TH_3342|M.thermoresistible__bu SEHLAAGAGPLIEHLKEHGVIAQ--------------
Mflv_4366|M.gilvum_PYR-GCK SEHLCAAAGPLIDHLTTRGVIG---------------
Mvan_1978|M.vanbaalenii_PYR-1 SEHLCAASGPLIEHLTRRGVIQ---------------
Mb0170c|M.bovis_AF2122/97 VWQFTDGARRLTEALAETEVFG---------------
Rv0165c|M.tuberculosis_H37Rv RR---NRAHRLAVHRWGTQADGGPG------------
MMAR_0408|M.marinum_M VWQFTDAAHRLTQMLETNGIFN---------------
MAB_1705c|M.abscessus_ATCC_199 RDNWHTLIAAPEGAAHEERGAG---------------
MSMEG_6738|M.smegmatis_MC2_155 EQNWQTLSQVVEKLAAEETDTDG--------------