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GRPSTPILSTDRIATAALDLVNSTGGFTIPGLARRLKVSPSSLYNHVAGREQIVELLRERAMSEVNLPDL DTDRPWSDVVADIMRSYRRSFARYPRLIPLLTIHAVNSTQAFRMYNALAVTLGRAGFSAADSLRIITLID NYVLGSALDLAAPDEPWESGTEVGPELAAALATGAPKPARADDAFEFGLAVLLRGLTNP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0442 | - | - | 100% (200) | tetracycline repressor domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2583 | - | 4e-11 | 28.57% (203) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0561 | - | 2e-07 | 24.29% (210) | putative TetR family protein receptor protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 5e-07 | 25.00% (208) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4355 | - | 1e-07 | 24.27% (206) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 5e-07 | 25.00% (208) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4687 | - | 1e-16 | 29.33% (208) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 8e-12 | 29.35% (201) | putative regulatory protein |
| M. avium 104 | MAV_1586 | - | 5e-06 | 24.27% (206) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3622 | - | 6e-11 | 28.86% (201) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1315 | - | 8e-09 | 29.21% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRA-----------------RFTVSD
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRA-----------------RFTVSD
Mb1388c|M.bovis_AF2122/97 -------------MQTTPGKRQRRQRG-----------------SINPED
Rv1353c|M.tuberculosis_H37Rv -------------MQTTPGKRQRRQRG-----------------SINPED
MAV_1586|M.avium_104 -----------MAKQATADKRQRRERG-----------------SINPDD
Mflv_4355|M.gilvum_PYR-GCK -----------MARQATAEKRQRRERG-----------------SINPDD
MSMEG_0442|M.smegmatis_MC2_155 --------------------MGRPSTP-----------------ILSTDR
MAB_4687|M.abscessus_ATCC_1997 ----------------MTDERRMRGRP-----------------PLPMET
Mvan_1315|M.vanbaalenii_PYR-1 MSYAHGCTAVRLDRMTNEEERGTPPLPRALEVLWHDRAGGGRARRLSRQR
: .
MMAR_3679|M.marinum_M IASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEALVADA
MUL_3622|M.ulcerans_Agy99 IASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEALVADA
Mb1388c|M.bovis_AF2122/97 IISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDR
Rv1353c|M.tuberculosis_H37Rv IISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDR
MAV_1586|M.avium_104 IITGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDR
Mflv_4355|M.gilvum_PYR-GCK IIKGAFELAEQVGIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDR
MSMEG_0442|M.smegmatis_MC2_155 IATAALDLVN--STGGFTIPGLARRLKVSPSSLYNHVAGREQIVELLRER
MAB_4687|M.abscessus_ATCC_1997 IVDAALQIVDEEGGEALSMRALARRLDSGTATIYRHFANRTEVVAHVVDR
Mvan_1315|M.vanbaalenii_PYR-1 IVEAAIELADRDGLGALSMARLAERLGCGTMSLYRHVANKDELVTFMVSA
* .*: :.: . ::: *. * . ::* :. : :: : .
MMAR_3679|M.marinum_M VVADVKVPAP---TDDWRADVHAIATAMWETMRQHPNAIPLVLTRRTVSA
MUL_3622|M.ulcerans_Agy99 VVADVKVPAP---IDDWRADVHAIATAMWETMRQHPNAIPLVLTRRTVWA
Mb1388c|M.bovis_AF2122/97 ALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP
Rv1353c|M.tuberculosis_H37Rv ALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSP
MAV_1586|M.avium_104 ALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSP
Mflv_4355|M.gilvum_PYR-GCK ALRQYAFATPYVEARDWRETLANHARTMRKTFNGNPILCDLILIRSALSP
MSMEG_0442|M.smegmatis_MC2_155 AMSEVNLPDLDT-DRPWSDVVADIMRSYRRSFARYPRLIPLLTIHAVNST
MAB_4687|M.abscessus_ATCC_1997 VFGEVQLDDPALARMPWQDACIVSSRALFDALRRHPNVAMLLADQIPVGP
Mvan_1315|M.vanbaalenii_PYR-1 APG---HPPGTTDRADWRDALTDWAVGLWDVYHRHPWILHATVIGPPADP
. * * .
MMAR_3679|M.marinum_M SSYMV----ADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQAELAGPL
MUL_3622|M.ulcerans_Agy99 SSYMV----ADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQAELAGPL
Mb1388c|M.bovis_AF2122/97 KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRK
Rv1353c|M.tuberculosis_H37Rv KTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRK
MAV_1586|M.avium_104 KAARLGAQEMEKAVANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEK
Mflv_4355|M.gilvum_PYR-GCK RAAKVGVQQVEKAIGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREK
MSMEG_0442|M.smegmatis_MC2_155 QAFRM----YNALAVTLGRAGFSAADSLRIITLIDNYVLGSALDLAAP--
MAB_4687|M.abscessus_ATCC_1997 NVFMIR----EHTLTLCLQAGFSPAEAIRIYMTLGRYVLGFANQIGAEHR
Mvan_1315|M.vanbaalenii_PYR-1 GQLAW----LDAGLAALSGTGLSERDKLAAVMALLHFVRGASALDIEAAD
: :*.. : : : * *
MMAR_3679|M.marinum_M AGTGREKEQVAVAARIGGLAGAEHPHIAALAQASQRS---TPAADFERAL
MUL_3622|M.ulcerans_Agy99 AGTGREKEQVAVAARIGGLAGAEHPHIAALAQASQRS---TPAADFERAL
Mb1388c|M.bovis_AF2122/97 SQSAGSGP--SAIEHPVAIDPATTPLLAHATGRGHRIG-APDETNFEYGL
Rv1353c|M.tuberculosis_H37Rv SQSAGSGP--SAIEHPVAIDPATTPLLAHATGRGHRIG-APDETNFEYGL
MAV_1586|M.avium_104 NQSSDVGP--RAIEDAVAIDPEKTPLLAQVTRIGHRIG-APDETNFEYGL
Mflv_4355|M.gilvum_PYR-GCK NLAGDDGH--GDIDDTMAIDPETAPLLAAVTQKGHHLS-ASDDRNFEFGL
MSMEG_0442|M.smegmatis_MC2_155 -------------DEPWESGTEVGPELAAALATGAPKP-ARADDAFEFGL
MAB_4687|M.abscessus_ATCC_1997 ASEAD------IAMLTRLVENIDLASYPSTLATAGVTL-VPLDEEFDFGL
Mvan_1315|M.vanbaalenii_PYR-1 HHDTAPDYP---ALLRRLVTGERFPALAAALQAEAFDADGDRLADFRSGL
. . * .*
MMAR_3679|M.marinum_M DILLAGIESFERRRDRR----------------------------
MUL_3622|M.ulcerans_Agy99 DILLAGIESFERRRDRR----------------------------
Mb1388c|M.bovis_AF2122/97 ECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR-
Rv1353c|M.tuberculosis_H37Rv ECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR-
MAV_1586|M.avium_104 TCILDHASRLIEEGKGAKAGPSRQRKPAKSSAAR--GRTKAPANR
Mflv_4355|M.gilvum_PYR-GCK DCILENAARLIEKAKTTRKAPARKR--------------------
MSMEG_0442|M.smegmatis_MC2_155 AVLLRGLTNP-----------------------------------
MAB_4687|M.abscessus_ATCC_1997 GLIVAGLEGLRHGE-------------------------------
Mvan_1315|M.vanbaalenii_PYR-1 DQFLDGIDSRVRRSR------------------------------
::