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VARQATAEKRQRRERGSINPDDIIKGAFELAEQVGIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMT DRALRQYAFATPYVEARDWRETLANHARTMRKTFNGNPILCDLILIRSALSPRAAKVGVQQVEKAIGSLV EAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGDDGHGDIDDTMAIDPETAPLLAAVTQKGHHLSAS DDRNFEFGLDCILENAARLIEKAKTTRKAPARKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4355 | - | - | 100% (244) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1322 | - | 2e-06 | 23.12% (160) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3625 | - | 6e-06 | 38.89% (54) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 8e-93 | 68.46% (241) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1353c | - | 8e-93 | 68.46% (241) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1508c | - | 2e-54 | 45.26% (232) | putative HTH-type transcriptional regulator |
| M. marinum M | MMAR_4019 | - | 1e-103 | 74.29% (245) | transcriptional regulatory protein |
| M. avium 104 | MAV_1586 | - | 1e-105 | 75.82% (244) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2225 | - | 1e-105 | 78.33% (240) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1116 | - | 8e-91 | 69.17% (240) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_3884 | - | 1e-101 | 73.06% (245) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1989 | - | 1e-126 | 91.39% (244) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4355|M.gilvum_PYR-GCK --------MARQATAE------KRQRRERGSINPDDIIKGAFELAEQVGI
Mvan_1989|M.vanbaalenii_PYR-1 --------MAKQATAE------KRQRRERGSINPDDIIKGAFELAEQVGI
MSMEG_2225|M.smegmatis_MC2_155 --------MAKQPAAE------KRQRRERGSINPEDIIKGAFELAEKVSI
MMAR_4019|M.marinum_M ---MEVPVVAKRAAAD------KRQRRERGSINPDDIISGAFELAEQVSI
MUL_3884|M.ulcerans_Agy99 ---MEVPVVAKRAAAD------KRQRRERGSINPDDIISGAFELAEQVSI
MAV_1586|M.avium_104 --------MAKQATAD------KRQRRERGSINPDDIITGAFELAEQVSI
Mb1388c|M.bovis_AF2122/97 ----------MQTTPG------KRQRRQRGSINPEDIISGAFELAQQVSI
Rv1353c|M.tuberculosis_H37Rv ----------MQTTPG------KRQRRQRGSINPEDIISGAFELAQQVSI
TH_1116|M.thermoresistible__bu --------VAKQATAD------KRRRRERGSINPDDIVAGAFELAEEVGI
MAB_1508c|M.abscessus_ATCC_199 MRHAGVGHEARTTSTQGPSHSPKRERRRRGSITAEDIIAGAFELAEEIGI
.:. **.**.****..:**: ******:::.*
Mflv_4355|M.gilvum_PYR-GCK DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALRQYAFATPYVEA
Mvan_1989|M.vanbaalenii_PYR-1 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALRQYAFATPYVEA
MSMEG_2225|M.smegmatis_MC2_155 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALREFVVATPYVEA
MMAR_4019|M.marinum_M DNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEA
MUL_3884|M.ulcerans_Agy99 DNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEG
MAV_1586|M.avium_104 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEA
Mb1388c|M.bovis_AF2122/97 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEA
Rv1353c|M.tuberculosis_H37Rv DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEA
TH_1116|M.thermoresistible__bu DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNEMTNRALRQYVFETPYVEA
MAB_1508c|M.abscessus_ATCC_199 SGLSMPLLAKHLDVGVTSIYWYFRKKGELLDAMTDRATKQYHFAAPFVGD
..****:*.***.*************.:**: **:** :: . :*::
Mflv_4355|M.gilvum_PYR-GCK RDWRETLANHARTMRKTFNGNPILCDLILIR-SALSPRAAKVGVQQVEKA
Mvan_1989|M.vanbaalenii_PYR-1 KDWRETLANHARSMRQTFNGNPILCDLILIR-SALSPRAAKLGVQEVERA
MSMEG_2225|M.smegmatis_MC2_155 KDWRESLANHARTMRKAFMGNPILCDLILIR-SALSPRAARVGVQEVESA
MMAR_4019|M.marinum_M SDWRETLRNHARLMRKTFMGNPILCDLILIR-SALSPKAARLGAQEMERA
MUL_3884|M.ulcerans_Agy99 SDWRETLRNHARLMRKTFMSNPILCDLILIR-SALSPKTARLGAQKMERA
MAV_1586|M.avium_104 SDWRETLRNHARLMRKTFMGNPILCDLILIR-AALSPKAARLGAQEMEKA
Mb1388c|M.bovis_AF2122/97 GDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLGAQEMEKA
Rv1353c|M.tuberculosis_H37Rv GDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLGAQEMEKA
TH_1116|M.thermoresistible__bu GNWRESLRNHARNMRKTFLSSPILTDLVLIR-GALNTKIRKLGLQQMEAA
MAB_1508c|M.abscessus_ATCC_199 ETWQDALRSHTHRMREAFRERPVLVELILMRTSELSSEALQASIQNLESL
*:::* .*:: **::* *:* :*:*:* . *... : . *::*
Mflv_4355|M.gilvum_PYR-GCK IGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGDDGHGDIDD
Mvan_1989|M.vanbaalenii_PYR-1 IGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGEDGHGDIDD
MSMEG_2225|M.smegmatis_MC2_155 IAGLVEAGLSVEDAFDTYSAVSVHVRGSVVLHRLYEKNRANDNAPGDFEE
MMAR_4019|M.marinum_M IANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIED
MUL_3884|M.ulcerans_Agy99 IANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIED
MAV_1586|M.avium_104 VANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAIED
Mb1388c|M.bovis_AF2122/97 IANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH
Rv1353c|M.tuberculosis_H37Rv IANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH
TH_1116|M.thermoresistible__bu IDSLVQAGLSPEDAFDTYSAVSVHVRGSVVLERLHEKTQDLFNGG---DE
MAB_1508c|M.abscessus_ATCC_199 VRTLIGVGFSPDNALDVYFALSLHIRGVVVLEHMDTVMPASGEAR-----
: *: .*:* ::*:* * *:*:*:** ***.:: .
Mflv_4355|M.gilvum_PYR-GCK TMAIDPETAPLLAAVTQKGHHLSASDDRNFEFGLDCILENAARLIEK-AK
Mvan_1989|M.vanbaalenii_PYR-1 TMTIDPESAPLLAAVTQKGHHLSASDDRNFEYGLECILDHAARLIEQNAK
MSMEG_2225|M.smegmatis_MC2_155 AMVIDPETTPLLAQVTSEGHRIGAADEQNFEYGLKCILDHAARLIEE--K
MMAR_4019|M.marinum_M AMNIDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAK
MUL_3884|M.ulcerans_Agy99 AMNIDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAK
MAV_1586|M.avium_104 AVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEE-GK
Mb1388c|M.bovis_AF2122/97 PVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSK
Rv1353c|M.tuberculosis_H37Rv PVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSK
TH_1116|M.thermoresistible__bu PSAVDPASTPIIAELLAKGHRLAEADERNFEYTLECILDHAERLIEERAA
MAB_1508c|M.abscessus_ATCC_199 SLVPSATLAPTLHELASRGHSIATISDANFDFTVEAIIERAENLLAQDIA
. .. :* : ** :. .: **:: : .*::.* .*: :
Mflv_4355|M.gilvum_PYR-GCK TTRKAP--------------ARKR-----
Mvan_1989|M.vanbaalenii_PYR-1 PARKATPA---------KSTARKR-----
MSMEG_2225|M.smegmatis_MC2_155 PAKKTR---------------RKVTAG--
MMAR_4019|M.marinum_M AAKSAPSR-PRKAAKPPAPRTRAKATTR-
MUL_3884|M.ulcerans_Agy99 AAKSAPSR-PRKAAKPPAPRTRAKATTR-
MAV_1586|M.avium_104 GAKAGPSR-QRKPAKSSAARGRTKAPANR
Mb1388c|M.bovis_AF2122/97 AAGEVAVRRPTATADAPTPGARAKAVAR-
Rv1353c|M.tuberculosis_H37Rv AAGEVAVRRPTATADAPTPGARAKAVAR-
TH_1116|M.thermoresistible__bu GGTRK------------------------
MAB_1508c|M.abscessus_ATCC_199 AREAS------------------------