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AKQATADKRQRRERGSINPDDIITGAFELAEQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTD RALSKYVFATPYVEASDWRETLRNHARLMRKTFMGNPILCDLILIRAALSPKAARLGAQEMEKAVANLVQ AGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAIEDAVAIDPEKTPLLAQVTRIGHRIGAPD ETNFEYGLTCILDHASRLIEEGKGAKAGPSRQRKPAKSSAARGRTKAPANR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1586 | - | - | 100% (262) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 1e-108 | 79.12% (249) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4355 | - | 1e-105 | 75.82% (244) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 1e-108 | 79.12% (249) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1508c | - | 3e-51 | 44.83% (232) | putative HTH-type transcriptional regulator |
| M. marinum M | MMAR_4019 | - | 1e-122 | 84.56% (259) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2225 | - | 1e-106 | 79.32% (237) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1116 | - | 3e-93 | 71.98% (232) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_3884 | - | 1e-121 | 83.01% (259) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1989 | - | 1e-106 | 75.49% (253) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4355|M.gilvum_PYR-GCK --------MARQATAE------KRQRRERGSINPDDIIKGAFELAEQVGI
Mvan_1989|M.vanbaalenii_PYR-1 --------MAKQATAE------KRQRRERGSINPDDIIKGAFELAEQVGI
MSMEG_2225|M.smegmatis_MC2_155 --------MAKQPAAE------KRQRRERGSINPEDIIKGAFELAEKVSI
Mb1388c|M.bovis_AF2122/97 ----------MQTTPG------KRQRRQRGSINPEDIISGAFELAQQVSI
Rv1353c|M.tuberculosis_H37Rv ----------MQTTPG------KRQRRQRGSINPEDIISGAFELAQQVSI
MMAR_4019|M.marinum_M ---MEVPVVAKRAAAD------KRQRRERGSINPDDIISGAFELAEQVSI
MUL_3884|M.ulcerans_Agy99 ---MEVPVVAKRAAAD------KRQRRERGSINPDDIISGAFELAEQVSI
MAV_1586|M.avium_104 --------MAKQATAD------KRQRRERGSINPDDIITGAFELAEQVSI
TH_1116|M.thermoresistible__bu --------VAKQATAD------KRRRRERGSINPDDIVAGAFELAEEVGI
MAB_1508c|M.abscessus_ATCC_199 MRHAGVGHEARTTSTQGPSHSPKRERRRRGSITAEDIIAGAFELAEEIGI
.:. **.**.****..:**: ******:::.*
Mflv_4355|M.gilvum_PYR-GCK DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALRQYAFATPYVEA
Mvan_1989|M.vanbaalenii_PYR-1 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALRQYAFATPYVEA
MSMEG_2225|M.smegmatis_MC2_155 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALREFVVATPYVEA
Mb1388c|M.bovis_AF2122/97 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEA
Rv1353c|M.tuberculosis_H37Rv DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEA
MMAR_4019|M.marinum_M DNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEA
MUL_3884|M.ulcerans_Agy99 DNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEG
MAV_1586|M.avium_104 DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEA
TH_1116|M.thermoresistible__bu DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNEMTNRALRQYVFETPYVEA
MAB_1508c|M.abscessus_ATCC_199 SGLSMPLLAKHLDVGVTSIYWYFRKKGELLDAMTDRATKQYHFAAPFVGD
..****:*.***.*************.:**: **:** :: . :*::
Mflv_4355|M.gilvum_PYR-GCK RDWRETLANHARTMRKTFNGNPILCDLILIR-SALSPRAAKVGVQQVEKA
Mvan_1989|M.vanbaalenii_PYR-1 KDWRETLANHARSMRQTFNGNPILCDLILIR-SALSPRAAKLGVQEVERA
MSMEG_2225|M.smegmatis_MC2_155 KDWRESLANHARTMRKAFMGNPILCDLILIR-SALSPRAARVGVQEVESA
Mb1388c|M.bovis_AF2122/97 GDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLGAQEMEKA
Rv1353c|M.tuberculosis_H37Rv GDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLGAQEMEKA
MMAR_4019|M.marinum_M SDWRETLRNHARLMRKTFMGNPILCDLILIR-SALSPKAARLGAQEMERA
MUL_3884|M.ulcerans_Agy99 SDWRETLRNHARLMRKTFMSNPILCDLILIR-SALSPKTARLGAQKMERA
MAV_1586|M.avium_104 SDWRETLRNHARLMRKTFMGNPILCDLILIR-AALSPKAARLGAQEMEKA
TH_1116|M.thermoresistible__bu GNWRESLRNHARNMRKTFLSSPILTDLVLIR-GALNTKIRKLGLQQMEAA
MAB_1508c|M.abscessus_ATCC_199 ETWQDALRSHTHRMREAFRERPVLVELILMRTSELSSEALQASIQNLESL
*:::* .*:: **::* *:* :*:*:* . *... : . *::*
Mflv_4355|M.gilvum_PYR-GCK IGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGDDGHGDIDD
Mvan_1989|M.vanbaalenii_PYR-1 IGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGEDGHGDIDD
MSMEG_2225|M.smegmatis_MC2_155 IAGLVEAGLSVEDAFDTYSAVSVHVRGSVVLHRLYEKNRANDNAPGDFEE
Mb1388c|M.bovis_AF2122/97 IANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH
Rv1353c|M.tuberculosis_H37Rv IANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH
MMAR_4019|M.marinum_M IANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIED
MUL_3884|M.ulcerans_Agy99 IANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIED
MAV_1586|M.avium_104 VANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAIED
TH_1116|M.thermoresistible__bu IDSLVQAGLSPEDAFDTYSAVSVHVRGSVVLERLHEKTQDLFNGG---DE
MAB_1508c|M.abscessus_ATCC_199 VRTLIGVGFSPDNALDVYFALSLHIRGVVVLEHMDTVMPASGEAR-----
: *: .*:* ::*:* * *:*:*:** ***.:: .
Mflv_4355|M.gilvum_PYR-GCK TMAIDPETAPLLAAVTQKGHHLSASDDRNFEFGLDCILENAARLIEK-AK
Mvan_1989|M.vanbaalenii_PYR-1 TMTIDPESAPLLAAVTQKGHHLSASDDRNFEYGLECILDHAARLIEQNAK
MSMEG_2225|M.smegmatis_MC2_155 AMVIDPETTPLLAQVTSEGHRIGAADEQNFEYGLKCILDHAARLIEE--K
Mb1388c|M.bovis_AF2122/97 PVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSK
Rv1353c|M.tuberculosis_H37Rv PVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSK
MMAR_4019|M.marinum_M AMNIDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAK
MUL_3884|M.ulcerans_Agy99 AMNIDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAK
MAV_1586|M.avium_104 AVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEE-GK
TH_1116|M.thermoresistible__bu PSAVDPASTPIIAELLAKGHRLAEADERNFEYTLECILDHAERLIEERAA
MAB_1508c|M.abscessus_ATCC_199 SLVPSATLAPTLHELASRGHSIATISDANFDFTVEAIIERAENLLAQDIA
. .. :* : ** :. .: **:: : .*::.* .*: :
Mflv_4355|M.gilvum_PYR-GCK TTRKAP--------------ARKR-----
Mvan_1989|M.vanbaalenii_PYR-1 PARKATPA---------KSTARKR-----
MSMEG_2225|M.smegmatis_MC2_155 PAKKTR---------------RKVTAG--
Mb1388c|M.bovis_AF2122/97 AAGEVAVRRPTATADAPTPGARAKAVAR-
Rv1353c|M.tuberculosis_H37Rv AAGEVAVRRPTATADAPTPGARAKAVAR-
MMAR_4019|M.marinum_M AAKSAPSR-PRKAAKPPAPRTRAKATTR-
MUL_3884|M.ulcerans_Agy99 AAKSAPSR-PRKAAKPPAPRTRAKATTR-
MAV_1586|M.avium_104 GAKAGPSR-QRKPAKSSAARGRTKAPANR
TH_1116|M.thermoresistible__bu GGTRK------------------------
MAB_1508c|M.abscessus_ATCC_199 AREAS------------------------