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M. smegmatis MC2 155 MSMEG_0389 (-)

annotation: glycosyl transferase
coordinates: 438130 - 439398
length: 422

MKFVLASYGTRGDIEPSVVVGRELQSRGHTVLMAVPPDLIEFTEAANLRTVAYGLDTKTWLDIYRNFWTF
ALHRFWKAREIRSLWREMWDLSDECWAQMNATLRSVAADADVLFAGQSYQEPAANVAEFYDVPLVTLHHI
PMRPNGRLVTFLPPVLARASMTAFDWFAWRLNKKVEDAQRRDLGLPKATGPSTQRIADRMSLEVQAYDEV
CFPGLAEEWAKWGELRPYVGTLTMELTTPADEEVSSWICGGTPPICFGFGSMPVESPADTVAMISSVCAE
LGERALICAGWSDFSDVALADHVKVVGAVNYATVFPGCRAVVHHGGSGTTAASLRAGLPTLVLSMDANQA
LWGAQIKRLKVGTTRRFSKTNRRTLIADLRTILDPAYAARAQALARGMTRPAESVVRAADVIEAFARSRC
SA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0389--100% (422)glycosyl transferase
M. smegmatis MC2 155MSMEG_0385-e-14559.17% (409) glycosyl transferase
M. smegmatis MC2 155MSMEG_0392-e-12855.61% (419) glycosyl transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1551-1e-12857.86% (420) glycosyltransferase
M. gilvum PYR-GCKMflv_0466-3e-0523.75% (240) glycosyl transferase family protein
M. tuberculosis H37RvRv1524-1e-12857.86% (420) glycosyltransferase
M. leprae Br4923MLBr_02348-1e-12454.03% (422) putative glycosyl transferase
M. abscessus ATCC 19977MAB_4107c-0.076.30% (422) glycosyltransferase GtfA
M. marinum MMMAR_2353-1e-12352.78% (413) UDP-glycosyltransferase
M. avium 104MAV_3265-0.075.18% (419) glycosyl transferase
M. thermoresistible (build 8)TH_1989-3e-4867.38% (141) Glycosyltransferase family protein 28
M. ulcerans Agy99MUL_1529-1e-10150.97% (361) UDP-glycosyltransferase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1551|M.bovis_AF2122/97            MKFVVASYG-TRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLS
Rv1524|M.tuberculosis_H37Rv         MKFVVASYG-TRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLS
MMAR_2353|M.marinum_M               MKFALAING-TRGDVEPCAALGRELSRRGHEVRVAVPPNLTGLAAAAGLE
MUL_1529|M.ulcerans_Agy99           ----MSNRA-LHSGGNYRAEATKDAS--------QYPPNLTGVAAAAGLE
MLBr_02348|M.leprae_Br4923          MKFTLAASG-SRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLA
MSMEG_0389|M.smegmatis_MC2_155      MKFVLASYG-TRGDIEPSVVVGRELQSRGHTVLMAVPPDLIEFTEAANLR
MAB_4107c|M.abscessus_ATCC_199      MKFVLASYG-TRGDIEPSVVVARELQRRGHDVVMAVPPDLISFTESAGLE
MAV_3265|M.avium_104                MKCVLASYG-TRGDIEPSVVVARELQRRGHDMIMAVPPDSVSFTEAAGLT
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK          MAVILAYTAPALGHLFPFCAVLQELARRGHDIHVRTLAAGLQICRDEGFT
                                                                                      

Mb1551|M.bovis_AF2122/97            AVAYGSRDSQEQLDEQ------FLHNAWKLQNPIKLLREAMAPVTEGWAE
Rv1524|M.tuberculosis_H37Rv         AVAYGSRDSQEQLDEQ------FLHNAWKLQNPIKLLREAMAPVTEGWAE
MMAR_2353|M.marinum_M               AVPYGP-DTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSD
MUL_1529|M.ulcerans_Agy99           AVPYCP-DTDELLNDE-----DNLQEFWKPQTSIKLVREGISDLRQAWSD
MLBr_02348|M.leprae_Br4923          AVAYGP-DTQEFLARDT---YSQWRQWWKILPPIKALQQ----LRQAWAD
MSMEG_0389|M.smegmatis_MC2_155      TVAYGL-DTKTWLDIYRNFWTFALHRFWKAREIRSLWREMWDLSDECWAQ
MAB_4107c|M.abscessus_ATCC_199      TVSYGL-DTKTWLDVYRNFWTFFFHTFWKVREIRTMWRQMWELSDECWAQ
MAV_3265|M.avium_104                AVPYGL-DSQAWLDVYRNFWTSFFRGFWKMGEMRGMWREMWDLSDQCWAQ
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK          AAAVDPRIEAIQADDT------------LTGTVRAAADTVEVLTARAPLE
                                                                                      

Mb1551|M.bovis_AF2122/97            LSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGE
Rv1524|M.tuberculosis_H37Rv         LSAMLTPVAAGADLLLTGQIYQEVVANVAEHHGIPLAALH-FYPVRANGE
MMAR_2353|M.marinum_M               MAGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMH-FLPSRVNSR
MUL_1529|M.ulcerans_Agy99           MAGTLKTLADGADLVLTGMIHQGIALNAAEYYGIPLATMH-FLPSRVNSR
MLBr_02348|M.leprae_Br4923          MATDLKSLADGADLVMTGVVYQGVVANVAEYYGIPFGVLH-FVPARVNGK
MSMEG_0389|M.smegmatis_MC2_155      MNATLRSVAADADVLFAGQSYQEPAANVAEFYDVPLVTLH-HIPMRPNGR
MAB_4107c|M.abscessus_ATCC_199      MNTTLMSAAQGADVLFAGQSYQEPAANVAEYHDIPLVTLH-HIPMRPNGQ
MAV_3265|M.avium_104                MNTTLLSLADGADLLFAGQSYQEPAANVAEYYDLPLATLH-HVPMRPNGQ
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK          VADLLSAVESVQPDVVIVDANCWGAMSVAETLGRPWVVLSPFTPYLRSPG
                                                                                      

Mb1551|M.bovis_AF2122/97            IAFPARLPAPLVRSTITAIDWLYWRMTKGVED--AQRRELGLPKASTPAP
Rv1524|M.tuberculosis_H37Rv         IAFPARLPAPLVRSTITAIDWLYWRMTKGVED--AQRRELGLPKASTPAP
MMAR_2353|M.marinum_M               VIP--ILSPRLNRSVISALWWVHWRVTKNPEE--AQRRELGMAKASSSST
MUL_1529|M.ulcerans_Agy99           VIP--ILSPRLNRSVISALWWVHWRVTKNPEE--AQRRELGMAKASSSST
MLBr_02348|M.leprae_Br4923          IIP--SLPSPLNRAILATVWRAHWLLAKKPED--AQRRELGLPKATSLST
MSMEG_0389|M.smegmatis_MC2_155      LVT--FLPPVLARASMTAFDWFAWRLNKKVED--AQRRDLGLPKATGPST
MAB_4107c|M.abscessus_ATCC_199      LVT--ILPSRLGRAAMRAFDWVSWRLNKKVED--AQRRELRLPKASSPSP
MAV_3265|M.avium_104                VVS--VLPAPLARSAMTAFDWFCWRLNKKVED--AQRRELGLPKATGPSP
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK          APPFGPGATPWPGPLGRIRDWGIGLVTTAVFDRPFARQIAPLRRALGLTP
                                                                                      

Mb1551|M.bovis_AF2122/97            RRMAVRGSLEIQAYDALCFPGLAAEW---GGRRPFVGALTMESATDADDE
Rv1524|M.tuberculosis_H37Rv         RRMAVRGSLEIQAYDALCFPGLAAEW---GGRRPFVGALTMESATDADDE
MMAR_2353|M.marinum_M               SRILKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNE
MUL_1529|M.ulcerans_Agy99           SRILKGRSLEIQAYDELCFPGLAAEWAEWGDRRPFVGALTLEMPTESDNE
MLBr_02348|M.leprae_Br4923          RRIVKRGALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTLELPTAADNE
MSMEG_0389|M.smegmatis_MC2_155      QRIADRMSLEVQAYDEVCFPGLAEEWAKWGELRPYVGTLTMELTTPADEE
MAB_4107c|M.abscessus_ATCC_199      QRIAERRSLEIQGYDSVCFPGLATEWAKWNGLRPFVGSLTMAMTQEADEE
MAV_3265|M.avium_104                RRIAERGSLEIQAYDEVCFPGLAEEWAKWDGQRPFVGTLTMELTTEADDE
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_0466|M.gilvum_PYR-GCK          VRTAGDLLLRAPAVLVATGKPLEYPHTDWGETVTMIGPAVFEPRAAQRP-
                                                                                      

Mb1551|M.bovis_AF2122/97            VASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSD
Rv1524|M.tuberculosis_H37Rv         VASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERALICSGPSD
MMAR_2353|M.marinum_M               VLSWIASGTPPIYFGFGSMPVESPAATIAMISAACAELGERALICTGSND
MUL_1529|M.ulcerans_Agy99           VLSWIASGTPPIYFGFGSMPVESPAATIAIISAACAELGERALICTGSND
MLBr_02348|M.leprae_Br4923          VLSWIAAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGERALISVKPKD
MSMEG_0389|M.smegmatis_MC2_155      VSSWICGGTPPICFGFGSMPVESPADTVAMISSVCAELGERALICAGWSD
MAB_4107c|M.abscessus_ATCC_199      VASWIAGGTPPIFFGFGSMPVESPSAALEMIGSACAELGERALIGAGWSD
MAV_3265|M.avium_104                VMSWIRGGTPPICFGFGSMPVESPADTVDMIGTACAQLGERALLCAGRSD
TH_1989|M.thermoresistible__bu      -----------------------------MFASVCSRLGERALICAGGTD
Mflv_0466|M.gilvum_PYR-GCK          --SWLDHIDDPIVLVTTSSVGQSDAALVETAVEALRDEPVHLVVTAPTGD
                                                                     .      : ::     *

Mb1551|M.bovis_AF2122/97            ATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLIL
Rv1524|M.tuberculosis_H37Rv         ATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLIL
MMAR_2353|M.marinum_M               LGGLQAPENVKLVSGVSHAAVFPACRAVVHHGGAGTTAAGMRAGIPTLIL
MUL_1529|M.ulcerans_Agy99           LGGLQAPENVKLVSGVSHAAVFPACCAVVHHGGAGTTAAGMRAGIPTLIL
MLBr_02348|M.leprae_Br4923          LTQVPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLIL
MSMEG_0389|M.smegmatis_MC2_155      FSDVALADHVKVVGAVNYATVFPGCRAVVHHGGSGTTAASLRAGLPTLVL
MAB_4107c|M.abscessus_ATCC_199      FGGAQLPEHVKVVGAVNYATVFPACRAVVHHGGSGTTAASLRAGVPTLIL
MAV_3265|M.avium_104                FSGVPAPDHVKVVGPVNYATIFPACRAVVHHGGSGTTAASLRAGVPTLIL
TH_1989|M.thermoresistible__bu      IDGVPEYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLRAGVPSLVT
Mflv_0466|M.gilvum_PYR-GCK          VDVMTRPG-VTQVRFAPHSMLLEHAVCVITHGGMGVTQKALARGVPVCVV
                                             *. *  . :: ::  . .:: *** *.*   :  *:*  : 

Mb1551|M.bovis_AF2122/97            WVTSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRARE
Rv1524|M.tuberculosis_H37Rv         WVTSDQPIWAAQIKQLKVGRGRRFSSATKESLIADLRTILAPDYVTRARE
MMAR_2353|M.marinum_M               WIWIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILGPDYVARART
MUL_1529|M.ulcerans_Agy99           WIWIEQPIWLAQIKRLKIGSGRRLASTTKETLVSDLRCILGPDYVARP--
MLBr_02348|M.leprae_Br4923          WIFIEQPVWAAQIKRLKVGAGRRFSATTQRSLAADLRTILAPQYATRARE
MSMEG_0389|M.smegmatis_MC2_155      SMDANQALWGAQIKRLKVGTTRRFSKTNRRTLIADLRTILDPAYAARAQA
MAB_4107c|M.abscessus_ATCC_199      SMDANQTLWGGQVKKLKVGTTRRFSTTTRESLVADLRRILASDYADRARE
MAV_3265|M.avium_104                SMDANQTIWGAQLKRLKVGATRRFSATDRDSLVQDLRKILAPDYARRARE
TH_1989|M.thermoresistible__bu      WSSADQPYWGNQVKRLKVGTSRRFSHTTPDTLVADLRRILTPDYAVRARA
Mflv_0466|M.gilvum_PYR-GCK          PFGRDQFEVARRVELAGCGTRLPAGKLSVGRLRTAVKTAAT--MTGGAAR
                                        :*     :::    *     .      *   ::       .  .  

Mb1551|M.bovis_AF2122/97            IASRMTKPAASVTATADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv         IASRMTKPAASVTATADLLEDAARRAR--------
MMAR_2353|M.marinum_M               IANEMSKPGESATRAADLLENEVSVS---------
MUL_1529|M.ulcerans_Agy99           -------PG--LRRC--------------------
MLBr_02348|M.leprae_Br4923          VANRMSKPDESVNAAADLLEDKASRNKSRTRYQDC
MSMEG_0389|M.smegmatis_MC2_155      LARGMTRPAESVVRAADVIEAFARSRCSA------
MAB_4107c|M.abscessus_ATCC_199      LAAGMTKPGESAVAAADAMERFAQARCSA------
MAV_3265|M.avium_104                IAARMTKPADSVMKAADVVEDFVQSRSRTGRS---
TH_1989|M.thermoresistible__bu      VAARMTDPADSVVRAADLFETAVECAPGVAHRE--
Mflv_0466|M.gilvum_PYR-GCK          VAAGFAATG-GVARGADVVESRLVARCALPEEQ--
                                           .