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M. smegmatis MC2 155 MSMEG_0179 (-)

annotation: transcriptional regulator, GntR family protein
coordinates: 202876 - 203547
length: 223

LPDLSVNRSTTVERVSDALRAAVLSGELTPGTPLREVDLAERMKVSRGSVREALVRLSDEGLLRRTSFRG
VEVKQLTADEIRDLFVVRKLIELTAVDAAGTAGAAALAELRRAVDEFGQAIRTGAAVDRNRADMFVHITL
VGLLNSPRLSRIHGELMSELQLALVSQYRDSTILPGTELTNRHEEFLRMLLDGDTVGAREQLERRLDLAQ
RLLLGTADPGEN*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_0179 - - 100% (223) transcriptional regulator, GntR family protein
M. smegmatis MC2 155 MSMEG_2489 - 2e-19 34.59% (159) transcriptional regulator, GntR family protein, putative
M. smegmatis MC2 155 MSMEG_4057 - 6e-14 27.72% (202) transcriptional regulator, GntR family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0170c - 3e-09 33.87% (124) GntR family transcriptional regulator
M. gilvum PYR-GCK Mflv_0958 - 1e-10 25.60% (207) GntR family transcriptional regulator
M. tuberculosis H37Rv Rv0165c - 3e-09 33.87% (124) GntR family transcriptional regulator
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_4411c - 4e-21 32.88% (219) GntR family transcriptional regulator
M. marinum M MMAR_2244 - 6e-19 27.70% (213) GntR family transcriptional regulator
M. avium 104 MAV_5020 - 1e-10 35.77% (123) transcriptional regulator, GntR family protein
M. thermoresistible (build 8) TH_0156 - 4e-11 30.37% (214) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99 MUL_1833 - 5e-19 27.70% (213) GntR family transcriptional regulator
M. vanbaalenii PYR-1 Mvan_0931 - 4e-16 34.56% (217) GntR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0170c|M.bovis_AF2122/97           MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv        MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MAV_5020|M.avium_104                ---------------------------------------------MSMQP
TH_0156|M.thermoresistible__bu      -----------------------------------------MNAPITSRL
MSMEG_0179|M.smegmatis_MC2_155      ------------------------------------------MLPDLS--
MAB_4411c|M.abscessus_ATCC_199      --------------------------------------MTTLVPEEFAP-
MMAR_2244|M.marinum_M               ----------------------------------MLEEEAVVIPRADSPD
MUL_1833|M.ulcerans_Agy99           ----------------------------------MLEEEAVVIPRADSPD
Mflv_0958|M.gilvum_PYR-GCK          --------------------------------------------MADAQL
Mvan_0931|M.vanbaalenii_PYR-1       -----------------------------------------MPHRRHSVL
                                                                                      

Mb0170c|M.bovis_AF2122/97           RSQLP-LRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
Rv0165c|M.tuberculosis_H37Rv        RSQLP-LRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTP
MAV_5020|M.avium_104                RSRRP-LRRAQLSDEVAGHLRAAIMSGALRPGTFIRLDETAAELGVSVTP
TH_0156|M.thermoresistible__bu      GPNGGGRRRDQLSDEVAAQLRAEIMSGALRPGTYIRLDETAARLGVSITP
MSMEG_0179|M.smegmatis_MC2_155      ------VNRSTTVERVSDALRAAVLSGELTPGTPLREVDLAERMKVSRGS
MAB_4411c|M.abscessus_ATCC_199      ------LERQSTAELIAERLRIAIMRGVLAPGAQLGEASLAAQFAVSRGP
MMAR_2244|M.marinum_M               QTCGRLPARGTIGEQVADLIQESILSGEAKRGAPLREELIADRYQVSRRT
MUL_1833|M.ulcerans_Agy99           QTCGRLPARGTVGEQVADLIQESILSGEAKRGSPLREELIADRYQVSRRT
Mflv_0958|M.gilvum_PYR-GCK          QLAALPAAEGRRAEQVMAAVRAALDAGVMRPGVKYSVYQLADALQVSRTP
Mvan_0931|M.vanbaalenii_PYR-1       LGSLTVERPGGSQQVILDELRRAILDGAVPPGTPIPLAEVAEHFGVSRIP
                                                 : :   ::  :  *    *        *    **  .

Mb0170c|M.bovis_AF2122/97           VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA
Rv0165c|M.tuberculosis_H37Rv        VREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSA
MAV_5020|M.avium_104                VREALLKLRGEGMVQLEPHRGHVVLPLTRQDIEDIFWLQATIAKELAAAA
TH_0156|M.thermoresistible__bu      IREALRTLRGEGMVQLEPHRGHVVAPLTRGDIEDIFWLQATIARKLTAAA
MSMEG_0179|M.smegmatis_MC2_155      VREALVRLSDEGLLRRTSFRGVEVKQLTADEIRDLFVVRKLIELTAVDAA
MAB_4411c|M.abscessus_ATCC_199      LREAMQRLVSEGLLRSERNRGIFVIELTDDDVLDVYRSRSAIERAALECI
MMAR_2244|M.marinum_M               VRDALRVLESNGLVRHQRHKGSTVVDFSAEDITDMYRSREVLELDAAKRW
MUL_1833|M.ulcerans_Agy99           VRDALRVLESNGLVRHQRHKGSTVVDFSAGDITDMYRSREVLELDAAKRW
Mflv_0958|M.gilvum_PYR-GCK          VRDALLRLEEIGLIRFEARQGFRILLPDPREIADIVAIRFALEPPAAGRA
Mvan_0931|M.vanbaalenii_PYR-1       VRESLKTLIGEGLVAHRANSGYMVAQLTAAELGELYVARESLEAASLAAA
                                    :*:::  *   *::      *  :      :: ::   :  :        

Mb0170c|M.bovis_AF2122/97           TAHITDVEIDELDRINNALA---GAIGSGDAKTIASIEFAFHRVFNKASR
Rv0165c|M.tuberculosis_H37Rv        TAHITDVEIDELDRINNALA---GAIGSGDAKTIASIEFAFHRVFNKASR
MAV_5020|M.avium_104                TDHITDTEIDELDRINDALA---AAVGSGDAETIAGLEFGFHRVFNQASG
TH_0156|M.thermoresistible__bu      VDRITDAELDELTALNEALA---AAVDRGVVGEVAAAMSAFHRVLHRTTG
MSMEG_0179|M.smegmatis_MC2_155      GTAG-AAALAELRRAVDEFG---QAIRTGAAVDRNRADMFVHITLVGLLN
MAB_4411c|M.abscessus_ATCC_199      MTGDTVTAYRRLLVPVAVMT---EAAARGDVVAVTDADQDFHEVLVDCSG
MMAR_2244|M.marinum_M               CRAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLD
MUL_1833|M.ulcerans_Agy99           CRAGEVDSGYRFHRLTEALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLD
Mflv_0958|M.gilvum_PYR-GCK          AAVCGPPLADRLAERMELLR---RAAARGDEPGFAAHDLLLHDHILEAAG
Mvan_0931|M.vanbaalenii_PYR-1       VGNASEADFATAIDMNALLE---HAIREDDAVAYHRQSRRFHAALTGPSR
                                                      :     *               .*  :     

Mb0170c|M.bovis_AF2122/97           RIKLAWFLLNAARYMPAQVFAADP------RWGADAVNSHRQLIAALRRR
Rv0165c|M.tuberculosis_H37Rv        RIKLAWFLLNAARYMGAGVRGRP----------AMGRGRGEQSSAADRR-
MAV_5020|M.avium_104                RIKLAWFLLNAARYMPVLVYAADP------QWGRAAVDNHRQLIAALRRR
TH_0156|M.thermoresistible__bu      RIKLAWFLYHVARYMPPQIYATDQ------QWGTATVARHRELIAALRRR
MSMEG_0179|M.smegmatis_MC2_155      SPRLSRIHGELMSELQLALVSQYR--DSTILPGTELTNRHEEFLRMLLDG
MAB_4411c|M.abscessus_ATCC_199      SPRLRRAMRTLLLETRMLLGELQG--AYPDLS--EQVREHEVLCAAIGAG
MMAR_2244|M.marinum_M               SPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRDR
MUL_1833|M.ulcerans_Agy99           SPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRDR
Mflv_0958|M.gilvum_PYR-GCK          NNRARRIVRSLRESTRLLGGITAD----RSRTMSDIDAEHQPVVDAVIAN
Mvan_0931|M.vanbaalenii_PYR-1       MYRLLRMLETAWNLTEPVQPMVHVT----PDDRIRLHADHGEMLQAFLTR
                                      :                                               

Mb0170c|M.bovis_AF2122/97           DTAAVIEHTVWQFTDGARRLTEALAETEVFG------------------
Rv0165c|M.tuberculosis_H37Rv        --AAPPRHSRR---NRAHRLAVHRWGTQADGGPG---------------
MAV_5020|M.avium_104                DTAAVIEHTVWQFTDAAARLTAMRDRTGTPSNRG---------------
TH_0156|M.thermoresistible__bu      DTETATRVTVDLFTDSAQRLIAQLEKVGIWT------------------
MSMEG_0179|M.smegmatis_MC2_155      DTVGAREQLERRLDLAQRLLLGTADPGEN--------------------
MAB_4411c|M.abscessus_ATCC_199      DAPAAYRLIDEHMHDAVTRLMARRDPGSVE-------------------
MMAR_2244|M.marinum_M               DEQRSTQLISEHLRINRDVLIRIVAS-----------------------
MUL_1833|M.ulcerans_Agy99           DEQRSTQLISEHLRINRDVLIRIVAS-----------------------
Mflv_0958|M.gilvum_PYR-GCK          DPAAAAAAMRTHLTSTGRLLVAQAVRDQDSPLDAAAVWAEAVGANTELP
Mvan_0931|M.vanbaalenii_PYR-1       DVERLLGAAERHARRLNSVIATLSFETGLLAAEKDISSPQ---------
                                                       :

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_0179	-	-	100% (223)	transcriptional regulator, GntR family protein
M. smegmatis MC2 155	MSMEG_2489	-	2e-19	34.59% (159)	transcriptional regulator, GntR family protein, putative
M. smegmatis MC2 155	MSMEG_4057	-	6e-14	27.72% (202)	transcriptional regulator, GntR family protein