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M. marinum M MMAR_5095 (idsA1)

annotation: multifunctional geranylgeranyl pyrophosphate synthetase IdsA1
coordinates: 6174030 - 6175070
length: 346

AMSQMARPVRASTTPARITLLLNDIRLLIEPKQRAVIDNLSPELRLCAGFHIGWWEPDGRDSSVRHGKAV
RPALSITCARAAGGAMDAAIPAAVAVELVHDCSLLHDDIMDGDVTRRHRPAAWVVYGVPMAILTGDALLV
LALDLVHEGASGSALRKAALELCAGQSADLAFEQRTKVWLPECLQMAQQKTGALFGVACQLGALAAGADS
LVADQYAQFGRHLGLSFQLVDDILGIWGSESVTGKPVFSDLQSRKKSLPVVAALSSGTAAGAKLETLLGG
TEALSDHELSYAADLIEDAGGRAWAEGEALRHRGLALDALAAAEPEPTAAEDLLALAELMTVRAA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_5095idsA1-100% (346)multifunctional geranylgeranyl pyrophosphate synthetase IdsA1
M. marinum MMMAR_0282idsB_31e-6946.11% (321) polyprenyl synthetase IdsB_3
M. marinum MMMAR_3219idsB_13e-6944.71% (340) polyprenyl synthetase IdsB_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3431cidsA11e-7647.09% (327) multifunctional dimethylallyltransferase/farnesyl
M. gilvum PYR-GCKMflv_1848-9e-2731.15% (305) polyprenyl synthetase
M. tuberculosis H37RvRv3398cidsA11e-7647.09% (327) multifunctional dimethylallyltransferase/farnesyl
M. leprae Br4923MLBr_02277-2e-2229.89% (281) polyprenyl diphosphate synthase component
M. abscessus ATCC 19977MAB_1992c-2e-2732.18% (317) polyprenyl synthetase
M. avium 104MAV_2321-7e-2934.41% (311) polyprenyl synthetase
M. smegmatis MC2 155MSMEG_4240-1e-2633.75% (317) polyprenyl synthetase
M. thermoresistible (build 8)TH_0708idsA21e-2331.75% (315) PROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2
M. ulcerans Agy99MUL_3197idsB4e-4335.29% (340) polyprenyl synthetase IdsB
M. vanbaalenii PYR-1Mvan_1577-1e-2635.74% (291) polyprenyl synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       MPSGTTLSSEPALRPAVMEKRRRLLHRIALCAIAAPRRIVAIAALVMVGA
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       AIFGVPVAGSLAAGGFQDPGSESARATRVLTETFGRGDMQLVFAVTDPAG
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       VDSASARAAGLAIATLVGEDPAVADVVSTWTVAPEAAAALISADGRSGLV
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       VAELTGDENTAPRIAQALVDEVATTVQPRHETVAVLAGGSSIVYSQINSQ
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       TLRDVLLMEAIAIPLTFLVLVWVFKGLLAAALPVAVGGLAIVASMSVLRL
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       VAMWTDVSIFALNLTTALGLALAVDYTLLIVSRFRDEVAAGAPRDRALVT
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       TMVTAGRTVLFSALTVALSMAAMLLFPMYFLKSFAYAGLATVALCAVAAI
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       VVTPAVIALFGDRLDAFDIRRMLRRTPAAEPRGEQMFWYRSTKFVMRRAL
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       PVGLAGTALLVSLGLPFLGVSWGLPDDRVLPSSATAHRVGDMLRTEFSDN
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       SEAAVTVLVPDAEGLTPQDFERYAAEASTIEDVSMVSAPTGTFADGRRVG
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       PPAGGAGVQGGIAYLTVGSTTASFSPESERQLDRLRALPGPGGRPVQMTG
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       IAQINRDSVESIMARLPIVLGIIAVITFVLLFLLTGSLVLPVKALVLNAL
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       SLTAAFGALVWIFQDGNLGALGTTPTGTLVVNMPVLLFCIAFGLSMDYEV
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       FLLARIREFWLAGGRRDNDESVALGLAHTGRVVTAAALIMSISFGALIAA
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           --------------------------------------------------
Rv3398c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5095|M.marinum_M               --------------------------------------------------
MUL_3197|M.ulcerans_Agy99           --------------------------------------------------
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1577|M.vanbaalenii_PYR-1       QVSFMRMFGLGLMLAVLIDATLVRMVLLPAFMHLMGRWNWWAPAPLARWH
MSMEG_4240|M.smegmatis_MC2_155      --------------------------------------------------
TH_0708|M.thermoresistible__bu      --------------------------------------------------
MAV_2321|M.avium_104                --------------------------------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           -----------------------------------------MRGTDEKYG
Rv3398c|M.tuberculosis_H37Rv        -----------------------------------------MRGTDEKYG
MMAR_5095|M.marinum_M               -----------------------------------------MAMSQMARP
MUL_3197|M.ulcerans_Agy99           ------------------------------------------------MT
MLBr_02277|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          ---MRTVNGYATSTFTATGIAS--------------------RHD-----
Mvan_1577|M.vanbaalenii_PYR-1       ARRTGTAEQNANPTKSGAAIASNGRRRPRHGWVERGGGPQLSRGDGAGAQ
MSMEG_4240|M.smegmatis_MC2_155      ---------MDTAAPSAVELAG----------------------------
TH_0708|M.thermoresistible__bu      -----------------VELAN----------------------------
MAV_2321|M.avium_104                -------------------MTG----------------------------
MAB_1992c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3431c|M.bovis_AF2122/97           LPPQPDSDRMTRRTLPVLGLAH----------------------------
Rv3398c|M.tuberculosis_H37Rv        LPPQPDSDRMTRRTLPVLGLAH----------------------------
MMAR_5095|M.marinum_M               VRASTTPARIT----LLLNDIR----------------------------
MUL_3197|M.ulcerans_Agy99           ADGTCESDVPAAVVQLFLSSAR----------------------------
MLBr_02277|M.leprae_Br4923          ------------MVVAGINFGD----------------------------
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          ------LKWHSRLRDRVLAAITEFVDARCADALAGGP--VDVAEDVLRGL
Mvan_1577|M.vanbaalenii_PYR-1       LAEPGLMAWRDTVRTAVREHLEDFVRGECARRLDGGG--VDVAAELLCGF
MSMEG_4240|M.smegmatis_MC2_155      ---------------AVTEQLREYLRERRSDCAYIGPVYAELTAGVEEFV
TH_0708|M.thermoresistible__bu      ---------------AVTDELRDYLRQRREDSAYIGSDYTHMTAALEEFV
MAV_2321|M.avium_104                ---------------AITEQLRRYLHDRRAETAYIGDDYSGLIAALEEFV
MAB_1992c|M.abscessus_ATCC_199      -------------------------------------------------M
Mb3431c|M.bovis_AF2122/97           --------------ELITPTLRQMADRLDPHMRPVVSYHLGWSDERGRPV
Rv3398c|M.tuberculosis_H37Rv        --------------ELITPTLRQMADRLDPHMRPVVSYHLGWSDERGRPV
MMAR_5095|M.marinum_M               --------------LLIEPKQRAVIDNLSPELRLCAGFHIGWWEPDGRDS
MUL_3197|M.ulcerans_Agy99           --------------AACDPVLRRAVESMPEPLATMAGYYLGWWDIDRSAL
MLBr_02277|M.leprae_Br4923          --------------AAFAATVQDRVVRIEQLMDAELRDTDEVMTESVLHL
                                                                                      

Mflv_1848|M.gilvum_PYR-GCK          LAD-GKCLRSTFLYVGWRCGADGT-----DAAIRAAASLEFLHAFALMQD
Mvan_1577|M.vanbaalenii_PYR-1       LDG-GKYVRSTYMYLGWLCGERED-----TAALRASASLELLHTFALIQD
MSMEG_4240|M.smegmatis_MC2_155      LRG-GKRVRPAFAYWGWRSVIEPADAVAGPDVLRLFSALELLQACALIHD
TH_0708|M.thermoresistible__bu      LRG-GKRIRPAFAYWGWRAVADEPAPVP-PEIMRLFAALELLHACALVHD
MAV_2321|M.avium_104                LNG-GKRLRPAFAYWGWRAVATEAPDDQ---ALLLFSALELLHACALVHD
MAB_1992c|M.abscessus_ATCC_199      LRG-GKRLRPAFAYWGWRAITDDPDPWN-PEVLRVCAALELLHTCALIHD
Mb3431c|M.bovis_AF2122/97           NNNCGKAIRPALVFVAAEAAGADPH-----SAIPGAVSVELVHNFSLVHD
Rv3398c|M.tuberculosis_H37Rv        NNNCGKAIRPALVFVAAEAAGADPH-----SAIPGAVSVELVHNFSLVHD
MMAR_5095|M.marinum_M               SVRHGKAVRPALSITCARAAGGAMD-----AAIPAAVAVELVHDCSLLHD
MUL_3197|M.ulcerans_Agy99           AGSSGTFVRAALVWAAAAACGGDAG-----NAAPIAAAVELVHSGTLLHD
MLBr_02277|M.leprae_Br4923          FAAGGKRFRPLFTVLSAQIGPRPDAP----EVIIAGAVIELVHLASLYHD
                                        *. .*.                            :*:::  :* :*

Mflv_1848|M.gilvum_PYR-GCK          DVMDESPMRRGRPTAHRAFANWHHANGLSGSSTRFGESAAVLLADLCLVW
Mvan_1577|M.vanbaalenii_PYR-1       DVMDSSPMRRARPSAHVALGRWHRDRALSGSASRFGESAAILLGDLCLVW
MSMEG_4240|M.smegmatis_MC2_155      DVIDDSATRRGLPTVHRLFTEQHHERGWLGSERQFGLSAAILAGDLALSW
TH_0708|M.thermoresistible__bu      DVIDASATRRGLPTVHRLFADTHRSRGWRGSAEQFGLSAAILLGDLALVW
MAV_2321|M.avium_104                DVIDDSATRRGRPTTHVRFASLHRDRQWQGSPERFGMSAAILLGDLALAW
MAB_1992c|M.abscessus_ATCC_199      DVIDSSATRRGEPTIHVEFAALHRENGWSGSPEQFGISAAILLGDLALTW
Mb3431c|M.bovis_AF2122/97           DLMDRDEHRRHRPTVWALWG----------------DAMALLAGDAMLSL
Rv3398c|M.tuberculosis_H37Rv        DLMDRDEHRRHRPTVWALWG----------------DAMALLAGDAMLSL
MMAR_5095|M.marinum_M               DIMDGDVTRRHRPAAWVVYG----------------VPMAILTGDALLVL
MUL_3197|M.ulcerans_Agy99           DVMAGEVTRGGRRAVWSIWG----------------IDNAILLGDALQTA
MLBr_02277|M.leprae_Br4923          DVMDEAEVRRGAPSANLRWS----------------NSVAILAGDYLFAT
                                    *::     *    :                         *:* .*     

Mflv_1848|M.gilvum_PYR-GCK          AEQMLRESGVDAAALDRAWPRYDTMRTELAVGQFADLVNDTATFPSLDAV
Mvan_1577|M.vanbaalenii_PYR-1       AEEMLRRSGVDADALARVWPRYDAMRTELAIGQLSDLLNSCQTFPTLPEV
MSMEG_4240|M.smegmatis_MC2_155      ADDIVAGADLPVDAHRRVQTVWRHIRTEVLGGQYLDIVTESSGDESVASA
TH_0708|M.thermoresistible__bu      ADDAVGSAGLSVDAHRRVRRVWADIRTEVLGGQYLDIVNESSGADSVASA
MAV_2321|M.avium_104                ADDIVLGVDLTPQAARRVRRVWANIRTEVLGGQYLDIVAEASAAASIASA
MAB_1992c|M.abscessus_ATCC_199      ADDMVVGAQLSPEAHVRARGVWSILRSEVLGGQYLDILSESSGDESVETA
Mb3431c|M.bovis_AF2122/97           AHEVLLDCDSP--HVGAALRAISEATRELIRGQAADTAFESRTDVALDEC
Rv3398c|M.tuberculosis_H37Rv        AHEVLLDCDSP--HVGAALRAISEATRELIRGQAADTAFESRTDVALDEC
MMAR_5095|M.marinum_M               ALDLVHEGAS-----GSALR---KAALELCAGQSADLAFEQRTKVWLPEC
MUL_3197|M.ulcerans_Agy99           AIRTLTDLPDPG-VAVRAVMRLETSCLDLCIGRFEDCAFECGQAGPVDSY
MLBr_02277|M.leprae_Br4923          ASRLVSQLGLD------AVRIIADTFAQLVTGQMRETRGVPEGADSIEQY
                                    *   :            .         ::  *:  :          :   

Mflv_1848|M.gilvum_PYR-GCK          LDVARRKSGNYTVRRPLEIGATLAGCDERQLSALAGYGSAVGEAFQMRDD
Mvan_1577|M.vanbaalenii_PYR-1       LDVLRRKSGNYTVRRPLELGAAMAGCSADVADALSGYGAAIGEAFQLRDD
MSMEG_4240|M.smegmatis_MC2_155      LNVNTFKTASYTVARPLQLGAAAAADRPDVQELFHRIGNDLGVAFQLRDD
TH_0708|M.thermoresistible__bu      MTVNTYKTASYTVTRPLQLGAAAAADRPDVLATFHEVGNDLGVAFQLRDD
MAV_2321|M.avium_104                MNVDTFKTACYTVSRPLQLGAAAAADRPDVHDLFSQFGTDLGVAFQLRDD
MAB_1992c|M.abscessus_ATCC_199      LRVIRFKTAGYTVQRPLQLGVAIAGENAEISRLLGDVGLDIGIAFQLRDD
Mb3431c|M.bovis_AF2122/97           LKMAEGKTAALMAAS-AEVGALLAGAPRSVREALVAYGRHIGLAFQLVDD
Rv3398c|M.tuberculosis_H37Rv        LKMAEGKTAALMAAS-AEVGALLAGAPRSVREALVAYGRHIGLAFQLVDD
MMAR_5095|M.marinum_M               LQMAQQKTGALFGVA-CQLGALAAGADSLVADQYAQFGRHLGLSFQLVDD
MUL_3197|M.ulcerans_Agy99           ERMAAGKTAALIGCC-CGLGALAADAGDATITALERFGRELGLAFQCVN-
MLBr_02277|M.leprae_Br4923          LKVVYEKTGCLIGSA-GRLGGLFAGAHAEQVERLSRLGSIVGTAFQISDD
                                      :   *:.         :*   *             *  :* :**  : 

Mflv_1848|M.gilvum_PYR-GCK          LLGVFGSPETTGKPAGDDLAARKATSVVAASYQLAN--DTQRRRLGALMT
Mvan_1577|M.vanbaalenii_PYR-1       ILGVFGSPSLTGKSVRSDLEDGKATSIVVAAYELAG--PRLRRQLAELMQ
MSMEG_4240|M.smegmatis_MC2_155      VLGVFGDPAVTGKPSGDDLRSGKRTVLLAEALELADASDPAAAALLRRSV
TH_0708|M.thermoresistible__bu      VLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEQRDPAAAELLRTAI
MAV_2321|M.avium_104                VLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKSDPLAAKLLRDSI
MAB_1992c|M.abscessus_ATCC_199      VLGVFGDPKVTGKPAGDDLRSGKRTVLLAEALRLARQRDSAAEDLLHSWI
Mb3431c|M.bovis_AF2122/97           LLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRRLAAWLVDET
Rv3398c|M.tuberculosis_H37Rv        LLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRRLAAWLVDET
MMAR_5095|M.marinum_M               ILGIWGSESVTGKPVFSDLQSRKKSLPVVAALSSGTAAGAKLETLLG---
MUL_3197|M.ulcerans_Agy99           -----------------DLGRRNATLTVAAALNSRSEAAIEPAALCH---
MLBr_02277|M.leprae_Br4923          IIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPDSERLRALLAG--
                                                     *:     :  :  :                   

Mflv_1848|M.gilvum_PYR-GCK          GGHLT-PADITHWQNLIAETGAVEWIEELIERRLTWALDSLDTADFDGEA
Mvan_1577|M.vanbaalenii_PYR-1       SPEIG-AADVDRWRTLIRASGAVQWIEEQIARRHDAALRFLDGAAIPAAP
MSMEG_4240|M.smegmatis_MC2_155      GTELS-DTQVRELCDAIESVGALAAVEQRIETLTRDALDVLAAANVHPQA
TH_0708|M.thermoresistible__bu      GTELS-DEQVTEVCGAIEKVGALRAVEDRIETLTTRALRRLDAAPIHEAA
MAV_2321|M.avium_104                GAQLS-DAEVDRLRDVIESVGALAAAEQRIATLTQRALATLAAAPINTAA
MAB_1992c|M.abscessus_ATCC_199      GTPLT-DQQVAEMCSLIVDLGALGAVESRIEEHTHRALDQLAGADIADDA
Mb3431c|M.bovis_AF2122/97           GSQTASDDELAAVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRP
Rv3398c|M.tuberculosis_H37Rv        GSQTASDDELAAVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRP
MMAR_5095|M.marinum_M               GTEALSDHELSYAADLIEDAGGRAWAEGEALRHRGLALDALAAAEPEPTA
MUL_3197|M.ulcerans_Agy99           SGSFMATGDIDRAATLVDVAAGR----HAVQRCADQRIQATVAALPDAVR
MLBr_02277|M.leprae_Br4923          --PVDNDAEVVEALALLRASPGMARARQVLAHYADQASGELAQLP-DGPS
                                            ::      :    .                            

Mflv_1848|M.gilvum_PYR-GCK          RDALATMAAACTERVA
Mvan_1577|M.vanbaalenii_PYR-1       RAALAEMAVACTQRAA
MSMEG_4240|M.smegmatis_MC2_155      KAGLSELARSAANRTA
TH_0708|M.thermoresistible__bu      KVGLSELARSAANRSA
MAV_2321|M.avium_104                KAGLSELAKLATNRSA
MAB_1992c|M.abscessus_ATCC_199      RAALSDLVRLVSNRSA
Mb3431c|M.bovis_AF2122/97           AAELQDLAHYIVDRQA
Rv3398c|M.tuberculosis_H37Rv        AAELQDLAHYIVDRQA
MMAR_5095|M.marinum_M               AEDLLALAELMTVRAA
MUL_3197|M.ulcerans_Agy99           SRDLIALSQLICCRER
MLBr_02277|M.leprae_Br4923          RDALATLVDYTTNRHG
                                       *  :      *