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AMSQMARPVRASTTPARITLLLNDIRLLIEPKQRAVIDNLSPELRLCAGFHIGWWEPDGRDSSVRHGKAV RPALSITCARAAGGAMDAAIPAAVAVELVHDCSLLHDDIMDGDVTRRHRPAAWVVYGVPMAILTGDALLV LALDLVHEGASGSALRKAALELCAGQSADLAFEQRTKVWLPECLQMAQQKTGALFGVACQLGALAAGADS LVADQYAQFGRHLGLSFQLVDDILGIWGSESVTGKPVFSDLQSRKKSLPVVAALSSGTAAGAKLETLLGG TEALSDHELSYAADLIEDAGGRAWAEGEALRHRGLALDALAAAEPEPTAAEDLLALAELMTVRAA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5095 | idsA1 | - | 100% (346) | multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 |
M. marinum M | MMAR_0282 | idsB_3 | 1e-69 | 46.11% (321) | polyprenyl synthetase IdsB_3 |
M. marinum M | MMAR_3219 | idsB_1 | 3e-69 | 44.71% (340) | polyprenyl synthetase IdsB_1 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3431c | idsA1 | 1e-76 | 47.09% (327) | multifunctional dimethylallyltransferase/farnesyl |
M. gilvum PYR-GCK | Mflv_1848 | - | 9e-27 | 31.15% (305) | polyprenyl synthetase |
M. tuberculosis H37Rv | Rv3398c | idsA1 | 1e-76 | 47.09% (327) | multifunctional dimethylallyltransferase/farnesyl |
M. leprae Br4923 | MLBr_02277 | - | 2e-22 | 29.89% (281) | polyprenyl diphosphate synthase component |
M. abscessus ATCC 19977 | MAB_1992c | - | 2e-27 | 32.18% (317) | polyprenyl synthetase |
M. avium 104 | MAV_2321 | - | 7e-29 | 34.41% (311) | polyprenyl synthetase |
M. smegmatis MC2 155 | MSMEG_4240 | - | 1e-26 | 33.75% (317) | polyprenyl synthetase |
M. thermoresistible (build 8) | TH_0708 | idsA2 | 1e-23 | 31.75% (315) | PROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2 |
M. ulcerans Agy99 | MUL_3197 | idsB | 4e-43 | 35.29% (340) | polyprenyl synthetase IdsB |
M. vanbaalenii PYR-1 | Mvan_1577 | - | 1e-26 | 35.74% (291) | polyprenyl synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 MPSGTTLSSEPALRPAVMEKRRRLLHRIALCAIAAPRRIVAIAALVMVGA MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 AIFGVPVAGSLAAGGFQDPGSESARATRVLTETFGRGDMQLVFAVTDPAG MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VDSASARAAGLAIATLVGEDPAVADVVSTWTVAPEAAAALISADGRSGLV MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VAELTGDENTAPRIAQALVDEVATTVQPRHETVAVLAGGSSIVYSQINSQ MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 TLRDVLLMEAIAIPLTFLVLVWVFKGLLAAALPVAVGGLAIVASMSVLRL MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VAMWTDVSIFALNLTTALGLALAVDYTLLIVSRFRDEVAAGAPRDRALVT MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 TMVTAGRTVLFSALTVALSMAAMLLFPMYFLKSFAYAGLATVALCAVAAI MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VVTPAVIALFGDRLDAFDIRRMLRRTPAAEPRGEQMFWYRSTKFVMRRAL MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 PVGLAGTALLVSLGLPFLGVSWGLPDDRVLPSSATAHRVGDMLRTEFSDN MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 SEAAVTVLVPDAEGLTPQDFERYAAEASTIEDVSMVSAPTGTFADGRRVG MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 PPAGGAGVQGGIAYLTVGSTTASFSPESERQLDRLRALPGPGGRPVQMTG MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 IAQINRDSVESIMARLPIVLGIIAVITFVLLFLLTGSLVLPVKALVLNAL MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 SLTAAFGALVWIFQDGNLGALGTTPTGTLVVNMPVLLFCIAFGLSMDYEV MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 FLLARIREFWLAGGRRDNDESVALGLAHTGRVVTAAALIMSISFGALIAA MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 QVSFMRMFGLGLMLAVLIDATLVRMVLLPAFMHLMGRWNWWAPAPLARWH MSMEG_4240|M.smegmatis_MC2_155 -------------------------------------------------- TH_0708|M.thermoresistible__bu -------------------------------------------------- MAV_2321|M.avium_104 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -----------------------------------------MRGTDEKYG Rv3398c|M.tuberculosis_H37Rv -----------------------------------------MRGTDEKYG MMAR_5095|M.marinum_M -----------------------------------------MAMSQMARP MUL_3197|M.ulcerans_Agy99 ------------------------------------------------MT MLBr_02277|M.leprae_Br4923 -------------------------------------------------- Mflv_1848|M.gilvum_PYR-GCK ---MRTVNGYATSTFTATGIAS--------------------RHD----- Mvan_1577|M.vanbaalenii_PYR-1 ARRTGTAEQNANPTKSGAAIASNGRRRPRHGWVERGGGPQLSRGDGAGAQ MSMEG_4240|M.smegmatis_MC2_155 ---------MDTAAPSAVELAG---------------------------- TH_0708|M.thermoresistible__bu -----------------VELAN---------------------------- MAV_2321|M.avium_104 -------------------MTG---------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 LPPQPDSDRMTRRTLPVLGLAH---------------------------- Rv3398c|M.tuberculosis_H37Rv LPPQPDSDRMTRRTLPVLGLAH---------------------------- MMAR_5095|M.marinum_M VRASTTPARIT----LLLNDIR---------------------------- MUL_3197|M.ulcerans_Agy99 ADGTCESDVPAAVVQLFLSSAR---------------------------- MLBr_02277|M.leprae_Br4923 ------------MVVAGINFGD---------------------------- Mflv_1848|M.gilvum_PYR-GCK ------LKWHSRLRDRVLAAITEFVDARCADALAGGP--VDVAEDVLRGL Mvan_1577|M.vanbaalenii_PYR-1 LAEPGLMAWRDTVRTAVREHLEDFVRGECARRLDGGG--VDVAAELLCGF MSMEG_4240|M.smegmatis_MC2_155 ---------------AVTEQLREYLRERRSDCAYIGPVYAELTAGVEEFV TH_0708|M.thermoresistible__bu ---------------AVTDELRDYLRQRREDSAYIGSDYTHMTAALEEFV MAV_2321|M.avium_104 ---------------AITEQLRRYLHDRRAETAYIGDDYSGLIAALEEFV MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------M Mb3431c|M.bovis_AF2122/97 --------------ELITPTLRQMADRLDPHMRPVVSYHLGWSDERGRPV Rv3398c|M.tuberculosis_H37Rv --------------ELITPTLRQMADRLDPHMRPVVSYHLGWSDERGRPV MMAR_5095|M.marinum_M --------------LLIEPKQRAVIDNLSPELRLCAGFHIGWWEPDGRDS MUL_3197|M.ulcerans_Agy99 --------------AACDPVLRRAVESMPEPLATMAGYYLGWWDIDRSAL MLBr_02277|M.leprae_Br4923 --------------AAFAATVQDRVVRIEQLMDAELRDTDEVMTESVLHL Mflv_1848|M.gilvum_PYR-GCK LAD-GKCLRSTFLYVGWRCGADGT-----DAAIRAAASLEFLHAFALMQD Mvan_1577|M.vanbaalenii_PYR-1 LDG-GKYVRSTYMYLGWLCGERED-----TAALRASASLELLHTFALIQD MSMEG_4240|M.smegmatis_MC2_155 LRG-GKRVRPAFAYWGWRSVIEPADAVAGPDVLRLFSALELLQACALIHD TH_0708|M.thermoresistible__bu LRG-GKRIRPAFAYWGWRAVADEPAPVP-PEIMRLFAALELLHACALVHD MAV_2321|M.avium_104 LNG-GKRLRPAFAYWGWRAVATEAPDDQ---ALLLFSALELLHACALVHD MAB_1992c|M.abscessus_ATCC_199 LRG-GKRLRPAFAYWGWRAITDDPDPWN-PEVLRVCAALELLHTCALIHD Mb3431c|M.bovis_AF2122/97 NNNCGKAIRPALVFVAAEAAGADPH-----SAIPGAVSVELVHNFSLVHD Rv3398c|M.tuberculosis_H37Rv NNNCGKAIRPALVFVAAEAAGADPH-----SAIPGAVSVELVHNFSLVHD MMAR_5095|M.marinum_M SVRHGKAVRPALSITCARAAGGAMD-----AAIPAAVAVELVHDCSLLHD MUL_3197|M.ulcerans_Agy99 AGSSGTFVRAALVWAAAAACGGDAG-----NAAPIAAAVELVHSGTLLHD MLBr_02277|M.leprae_Br4923 FAAGGKRFRPLFTVLSAQIGPRPDAP----EVIIAGAVIELVHLASLYHD *. .*. :*::: :* :* Mflv_1848|M.gilvum_PYR-GCK DVMDESPMRRGRPTAHRAFANWHHANGLSGSSTRFGESAAVLLADLCLVW Mvan_1577|M.vanbaalenii_PYR-1 DVMDSSPMRRARPSAHVALGRWHRDRALSGSASRFGESAAILLGDLCLVW MSMEG_4240|M.smegmatis_MC2_155 DVIDDSATRRGLPTVHRLFTEQHHERGWLGSERQFGLSAAILAGDLALSW TH_0708|M.thermoresistible__bu DVIDASATRRGLPTVHRLFADTHRSRGWRGSAEQFGLSAAILLGDLALVW MAV_2321|M.avium_104 DVIDDSATRRGRPTTHVRFASLHRDRQWQGSPERFGMSAAILLGDLALAW MAB_1992c|M.abscessus_ATCC_199 DVIDSSATRRGEPTIHVEFAALHRENGWSGSPEQFGISAAILLGDLALTW Mb3431c|M.bovis_AF2122/97 DLMDRDEHRRHRPTVWALWG----------------DAMALLAGDAMLSL Rv3398c|M.tuberculosis_H37Rv DLMDRDEHRRHRPTVWALWG----------------DAMALLAGDAMLSL MMAR_5095|M.marinum_M DIMDGDVTRRHRPAAWVVYG----------------VPMAILTGDALLVL MUL_3197|M.ulcerans_Agy99 DVMAGEVTRGGRRAVWSIWG----------------IDNAILLGDALQTA MLBr_02277|M.leprae_Br4923 DVMDEAEVRRGAPSANLRWS----------------NSVAILAGDYLFAT *:: * : *:* .* Mflv_1848|M.gilvum_PYR-GCK AEQMLRESGVDAAALDRAWPRYDTMRTELAVGQFADLVNDTATFPSLDAV Mvan_1577|M.vanbaalenii_PYR-1 AEEMLRRSGVDADALARVWPRYDAMRTELAIGQLSDLLNSCQTFPTLPEV MSMEG_4240|M.smegmatis_MC2_155 ADDIVAGADLPVDAHRRVQTVWRHIRTEVLGGQYLDIVTESSGDESVASA TH_0708|M.thermoresistible__bu ADDAVGSAGLSVDAHRRVRRVWADIRTEVLGGQYLDIVNESSGADSVASA MAV_2321|M.avium_104 ADDIVLGVDLTPQAARRVRRVWANIRTEVLGGQYLDIVAEASAAASIASA MAB_1992c|M.abscessus_ATCC_199 ADDMVVGAQLSPEAHVRARGVWSILRSEVLGGQYLDILSESSGDESVETA Mb3431c|M.bovis_AF2122/97 AHEVLLDCDSP--HVGAALRAISEATRELIRGQAADTAFESRTDVALDEC Rv3398c|M.tuberculosis_H37Rv AHEVLLDCDSP--HVGAALRAISEATRELIRGQAADTAFESRTDVALDEC MMAR_5095|M.marinum_M ALDLVHEGAS-----GSALR---KAALELCAGQSADLAFEQRTKVWLPEC MUL_3197|M.ulcerans_Agy99 AIRTLTDLPDPG-VAVRAVMRLETSCLDLCIGRFEDCAFECGQAGPVDSY MLBr_02277|M.leprae_Br4923 ASRLVSQLGLD------AVRIIADTFAQLVTGQMRETRGVPEGADSIEQY * : . :: *: : : Mflv_1848|M.gilvum_PYR-GCK LDVARRKSGNYTVRRPLEIGATLAGCDERQLSALAGYGSAVGEAFQMRDD Mvan_1577|M.vanbaalenii_PYR-1 LDVLRRKSGNYTVRRPLELGAAMAGCSADVADALSGYGAAIGEAFQLRDD MSMEG_4240|M.smegmatis_MC2_155 LNVNTFKTASYTVARPLQLGAAAAADRPDVQELFHRIGNDLGVAFQLRDD TH_0708|M.thermoresistible__bu MTVNTYKTASYTVTRPLQLGAAAAADRPDVLATFHEVGNDLGVAFQLRDD MAV_2321|M.avium_104 MNVDTFKTACYTVSRPLQLGAAAAADRPDVHDLFSQFGTDLGVAFQLRDD MAB_1992c|M.abscessus_ATCC_199 LRVIRFKTAGYTVQRPLQLGVAIAGENAEISRLLGDVGLDIGIAFQLRDD Mb3431c|M.bovis_AF2122/97 LKMAEGKTAALMAAS-AEVGALLAGAPRSVREALVAYGRHIGLAFQLVDD Rv3398c|M.tuberculosis_H37Rv LKMAEGKTAALMAAS-AEVGALLAGAPRSVREALVAYGRHIGLAFQLVDD MMAR_5095|M.marinum_M LQMAQQKTGALFGVA-CQLGALAAGADSLVADQYAQFGRHLGLSFQLVDD MUL_3197|M.ulcerans_Agy99 ERMAAGKTAALIGCC-CGLGALAADAGDATITALERFGRELGLAFQCVN- MLBr_02277|M.leprae_Br4923 LKVVYEKTGCLIGSA-GRLGGLFAGAHAEQVERLSRLGSIVGTAFQISDD : *:. :* * * :* :** : Mflv_1848|M.gilvum_PYR-GCK LLGVFGSPETTGKPAGDDLAARKATSVVAASYQLAN--DTQRRRLGALMT Mvan_1577|M.vanbaalenii_PYR-1 ILGVFGSPSLTGKSVRSDLEDGKATSIVVAAYELAG--PRLRRQLAELMQ MSMEG_4240|M.smegmatis_MC2_155 VLGVFGDPAVTGKPSGDDLRSGKRTVLLAEALELADASDPAAAALLRRSV TH_0708|M.thermoresistible__bu VLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEQRDPAAAELLRTAI MAV_2321|M.avium_104 VLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKSDPLAAKLLRDSI MAB_1992c|M.abscessus_ATCC_199 VLGVFGDPKVTGKPAGDDLRSGKRTVLLAEALRLARQRDSAAEDLLHSWI Mb3431c|M.bovis_AF2122/97 LLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRRLAAWLVDET Rv3398c|M.tuberculosis_H37Rv LLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRRLAAWLVDET MMAR_5095|M.marinum_M ILGIWGSESVTGKPVFSDLQSRKKSLPVVAALSSGTAAGAKLETLLG--- MUL_3197|M.ulcerans_Agy99 -----------------DLGRRNATLTVAAALNSRSEAAIEPAALCH--- MLBr_02277|M.leprae_Br4923 IIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPDSERLRALLAG-- *: : : : Mflv_1848|M.gilvum_PYR-GCK GGHLT-PADITHWQNLIAETGAVEWIEELIERRLTWALDSLDTADFDGEA Mvan_1577|M.vanbaalenii_PYR-1 SPEIG-AADVDRWRTLIRASGAVQWIEEQIARRHDAALRFLDGAAIPAAP MSMEG_4240|M.smegmatis_MC2_155 GTELS-DTQVRELCDAIESVGALAAVEQRIETLTRDALDVLAAANVHPQA TH_0708|M.thermoresistible__bu GTELS-DEQVTEVCGAIEKVGALRAVEDRIETLTTRALRRLDAAPIHEAA MAV_2321|M.avium_104 GAQLS-DAEVDRLRDVIESVGALAAAEQRIATLTQRALATLAAAPINTAA MAB_1992c|M.abscessus_ATCC_199 GTPLT-DQQVAEMCSLIVDLGALGAVESRIEEHTHRALDQLAGADIADDA Mb3431c|M.bovis_AF2122/97 GSQTASDDELAAVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRP Rv3398c|M.tuberculosis_H37Rv GSQTASDDELAAVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRP MMAR_5095|M.marinum_M GTEALSDHELSYAADLIEDAGGRAWAEGEALRHRGLALDALAAAEPEPTA MUL_3197|M.ulcerans_Agy99 SGSFMATGDIDRAATLVDVAAGR----HAVQRCADQRIQATVAALPDAVR MLBr_02277|M.leprae_Br4923 --PVDNDAEVVEALALLRASPGMARARQVLAHYADQASGELAQLP-DGPS :: : . Mflv_1848|M.gilvum_PYR-GCK RDALATMAAACTERVA Mvan_1577|M.vanbaalenii_PYR-1 RAALAEMAVACTQRAA MSMEG_4240|M.smegmatis_MC2_155 KAGLSELARSAANRTA TH_0708|M.thermoresistible__bu KVGLSELARSAANRSA MAV_2321|M.avium_104 KAGLSELAKLATNRSA MAB_1992c|M.abscessus_ATCC_199 RAALSDLVRLVSNRSA Mb3431c|M.bovis_AF2122/97 AAELQDLAHYIVDRQA Rv3398c|M.tuberculosis_H37Rv AAELQDLAHYIVDRQA MMAR_5095|M.marinum_M AEDLLALAELMTVRAA MUL_3197|M.ulcerans_Agy99 SRDLIALSQLICCRER MLBr_02277|M.leprae_Br4923 RDALATLVDYTTNRHG * : *