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AVLRRAQRECEPFLRNIIGSLAEPLATMAGYHFGWWDANGRDAAETSGKSLRAALAFGAARACGDAREAA PAAAAVELIHNFTLLHDDVMDGDSTRRGRATVWRVWGVNNAILLGDALHALAIRTLTDSLGQGVAVNAIT RLEQTCLDLCVGQHQDCSFERCTTVTVPDYLRMAAGKTAVLMACACALGAVSARADAATVAAVERFGYEL GLAFQIVDDLIGIWGDPARTGKPVGSDLASRKATLPIVVALSSDCEAALELARLYRSDHAMTHREVVHAA ELVETAGGRQAAQHFADERMRAAIAALPESMRCSELVALAQLVIDRDK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0282 | idsB_3 | - | 100% (329) | polyprenyl synthetase IdsB_3 |
| M. marinum M | MMAR_3219 | idsB_1 | e-117 | 63.61% (327) | polyprenyl synthetase IdsB_1 |
| M. marinum M | MMAR_3212 | idsB_2 | e-110 | 61.96% (326) | polyprenyl synthetase IdsB_2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3415c | idsB | 1e-115 | 63.72% (328) | polyprenyl synthetase IdsB |
| M. gilvum PYR-GCK | Mflv_1848 | - | 6e-25 | 30.60% (281) | polyprenyl synthetase |
| M. tuberculosis H37Rv | Rv3383c | idsB | 1e-115 | 63.72% (328) | polyprenyl synthetase IdsB |
| M. leprae Br4923 | MLBr_02277 | - | 9e-26 | 33.46% (266) | polyprenyl diphosphate synthase component |
| M. abscessus ATCC 19977 | MAB_3928c | - | 1e-22 | 33.70% (273) | polyprenyl-diphosphate synthase GrcC1 |
| M. avium 104 | MAV_4581 | - | 4e-26 | 39.50% (200) | polyprenyl synthetase |
| M. smegmatis MC2 155 | MSMEG_1133 | - | 2e-25 | 33.08% (266) | bifunctional short chain isoprenyl diphosphate synthase |
| M. thermoresistible (build 8) | TH_1767 | - | 1e-24 | 32.08% (265) | bifunctional short chain isoprenyl diphosphate synthase |
| M. ulcerans Agy99 | MUL_3197 | idsB | 1e-86 | 51.68% (327) | polyprenyl synthetase IdsB |
| M. vanbaalenii PYR-1 | Mvan_0992 | - | 3e-24 | 33.21% (265) | trans-hexaprenyltranstransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1133|M.smegmatis_MC2_155 -------------------MVAGVDFGDPAFAADVRDGVARIEDLMSDEL
Mvan_0992|M.vanbaalenii_PYR-1 -------------------MVAGVDFGDAEFAQDVRDGVARIEALMSEEL
TH_1767|M.thermoresistible__bu -------------------VVAGVDLGDPDFAAGVRDGVARIEDLMSSEL
MLBr_02277|M.leprae_Br4923 ------------------MVVAGINFGDAAFAATVQDRVVRIEQLMDAEL
MAV_4581|M.avium_104 -----------------------MDFGDPAFAATVRDGVGRIEQLMDTEL
MAB_3928c|M.abscessus_ATCC_199 --------------------MAGVDLGDPVFAAKVRDHLAAIETLIVSEL
Mb3415c|M.bovis_AF2122/97 MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLATMA
Rv3383c|M.tuberculosis_H37Rv MGGVLTLDAAFLGSVPADLGKALLERARADCGPVLHRAIESMREPLATMA
MUL_3197|M.ulcerans_Agy99 ----MTADGTCESDVPAAVVQLFLSSARAACDPVLRRAVESMPEPLATMA
MMAR_0282|M.marinum_M --------------------MAVLRRAQRECEPFLRNIIGSLAEPLATMA
Mflv_1848|M.gilvum_PYR-GCK -MRTVNGYATSTFTATGIASRHDLKWHSRLRDRVLAAITEFVDARCADAL
: : :
MSMEG_1133|M.smegmatis_MC2_155 GKADELMAEAVQHLFQAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVIE
Mvan_0992|M.vanbaalenii_PYR-1 GKADVLMAEAVQHLFQAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVIE
TH_1767|M.thermoresistible__bu GKADDLMAEAVQHLFRAGGKRFRPLFTVLSAQLGPEPDAWQVTVAGAVIE
MLBr_02277|M.leprae_Br4923 RDTDEVMTESVLHLFAAGGKRFRPLFTVLSAQIGPRPDAPEVIIAGAVIE
MAV_4581|M.avium_104 RSADDIMTELLTHLFKAGGKRFRPLFTVLSAQIGPDPDAAEVTIAGAVIE
MAB_3928c|M.abscessus_ATCC_199 GQSDPLLTESVLHLFHAGGKRFRPLFTVLAAQTGPDPDNDEVILAGAVCE
Mb3415c|M.bovis_AF2122/97 GYHLGWWNADRSTAAGSSGKYFR-AALVYAAAAACGGDVGDATPVSAAVE
Rv3383c|M.tuberculosis_H37Rv GYHLGWWNADRSTAAGSSGKYFR-AALVYAAAAACGGDVGDATPVSAAVE
MUL_3197|M.ulcerans_Agy99 GYYLGWWDIDRSALAGSSGTFVR-AALVWAAAAACGGDAGNAAPIAAAVE
MMAR_0282|M.marinum_M GYHFGWWDANGRDAAETSGKSLR-AALAFGAARACG-DAREAAPAAAAVE
Mflv_1848|M.gilvum_PYR-GCK AGGPVDVAEDVLRGLLADGKCLRSTFLYVGWRCGADGTDAAIR-AAASLE
:.*. .* . . .* *
MSMEG_1133|M.smegmatis_MC2_155 LVHLATLYHDDVMDEAQMRRGAQSAN----------------ARWGNNIA
Mvan_0992|M.vanbaalenii_PYR-1 LVHLATLYHDDVMDEAQVRRGAPSAN----------------ARWSNNIA
TH_1767|M.thermoresistible__bu LVHLATLYHDDVMDDAEMRRGAPSAN----------------AKWGNSIA
MLBr_02277|M.leprae_Br4923 LVHLASLYHDDVMDEAEVRRGAPSAN----------------LRWSNSVA
MAV_4581|M.avium_104 LVHLATLYHDDVMDEAEVRRGTPTAN----------------VRWGNNVA
MAB_3928c|M.abscessus_ATCC_199 LIHLATLYHDDVMDEAQKRRGVPSAN----------------ARWGNNVA
Mb3415c|M.bovis_AF2122/97 LVHNFTLLHDDVMDGDATRRGRPTVW----------------SVWGVGGA
Rv3383c|M.tuberculosis_H37Rv LVHNFTLLHDDVMDGDATRRGRPTVW----------------SVWGVGVA
MUL_3197|M.ulcerans_Agy99 LVHSGTLLHDDVMAGEVTRGGRRAVW----------------SIWGIDNA
MMAR_0282|M.marinum_M LIHNFTLLHDDVMDGDSTRRGRATVW----------------RVWGVNNA
Mflv_1848|M.gilvum_PYR-GCK FLHAFALMQDDVMDESPMRRGRPTAHRAFANWHHANGLSGSSTRFGESAA
::* :* :**** * * :. :. . *
MSMEG_1133|M.smegmatis_MC2_155 ILAGDYLFATASRLVS-----RLGPD-AVRVIADTFAQLVTGQMRETRGA
Mvan_0992|M.vanbaalenii_PYR-1 ILAGDYLFATASRLVS-----RLGPD-AVRIIADTFALLVTGQMRETRGA
TH_1767|M.thermoresistible__bu ILAGDYLFATASRLVS-----RLGPE-AVRVIADTFAQLVTGQMRETRGA
MLBr_02277|M.leprae_Br4923 ILAGDYLFATASRLVS-----QLGLD-AVRIIADTFAQLVTGQMRETRGV
MAV_4581|M.avium_104 ILAGDYLFATASRLVS-----RLGPE-AVQLIAETFAQLVTGQMRETRGR
MAB_3928c|M.abscessus_ATCC_199 ILAGDYLLATASRLVS-----RLGPT-AVRIVAETFAELVTGQMRETVGV
Mb3415c|M.bovis_AF2122/97 ILLGDALHATAVRILTGLTDECVAVR-AIRRLQMSCLDLCIGQFEDCLLE
Rv3383c|M.tuberculosis_H37Rv ILLGDALHATAVRILTGLTDECVAVR-AIRRLQMSCLDLCIGQFEDCLLE
MUL_3197|M.ulcerans_Agy99 ILLGDALQTAAIRTLTDLPDPGVAVR-AVMRLETSCLDLCIGRFEDCAFE
MMAR_0282|M.marinum_M ILLGDALHALAIRTLTDSLGQGVAVN-AITRLEQTCLDLCVGQHQDCSFE
Mflv_1848|M.gilvum_PYR-GCK VLLADLCLVWAEQMLRESGVDAAALDRAWPRYDTMRTELAVGQFADLVND
:* .* . * : : . * * *: :
MSMEG_1133|M.smegmatis_MC2_155 ADHVDSVDHYLKVVYEKTA-CLIAASGRFGATFSGANDEQIERLSRLGGI
Mvan_0992|M.vanbaalenii_PYR-1 ADHVDEVDHYLKVVYEKTA-CLIAASGRFGATFSGADDEQIERLARLGGI
TH_1767|M.thermoresistible__bu ADGADPIEHYLKVVYEKTA-CLISASGRFGATFSGADEEQVERLARLGGI
MLBr_02277|M.leprae_Br4923 PEGADSIEQYLKVVYEKTG-CLIGSAGRLGGLFAGAHAEQVERLSRLGSI
MAV_4581|M.avium_104 KEGSDPIEHYLKVVYEKTA-CLIAAAGRFGAMFSGADADQVERLSRLGGI
MAB_3928c|M.abscessus_ATCC_199 PEGGDETEHYLKVIHEKTG-SLIAAAGRFGAMTSRCDDDQIERLSRLGAI
Mb3415c|M.bovis_AF2122/97 GQPEVTVDDYLRMAAGKTA-ALTGCCCALGALVANADDATIAALERFGHE
Rv3383c|M.tuberculosis_H37Rv GQPEVTVDDYLRMAAGKTA-ALTGCCCALGALVANADDATIAALERFGHE
MUL_3197|M.ulcerans_Agy99 CGQAGPVDSYERMAAGKTA-ALIGCCCGLGALAADAGDATITALERFGRE
MMAR_0282|M.marinum_M RCTTVTVPDYLRMAAGKTA-VLMACACALGAVSARADAATVAAVERFGYE
Mflv_1848|M.gilvum_PYR-GCK TATFPSLDAVLDVARRKSGNYTVRRPLEIGATLAGCDERQLSALAGYGSA
: *:. :*. : . : : *
MSMEG_1133|M.smegmatis_MC2_155 VGTAFQIADDIIDIDSDPDESGKTPGTDLREGVHTLPVLYALRETGPDAD
Mvan_0992|M.vanbaalenii_PYR-1 VGTAFQISDDIIDIDSDPDESGKVPGTDLREGVHTLPVLYALRETGPDAD
TH_1767|M.thermoresistible__bu VGTAFQISDDIIDIESESTESGKTPGTDLREGVHTLPVLYALRETGPEAE
MLBr_02277|M.leprae_Br4923 VGTAFQISDDIIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPDSE
MAV_4581|M.avium_104 VGTAFQISDDIIDIDSDSHESGKLPGTDVREGVHTLPMVYALREPGPDAA
MAB_3928c|M.abscessus_ATCC_199 VGTAFQISDDIIDIESLTDESGKTPGTDLREGVHTLPMLYALRDTGPDAD
Mb3415c|M.bovis_AF2122/97 LGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAAT
Rv3383c|M.tuberculosis_H37Rv LGLAFQCVDDLIGIWGDPGVTGKPVGNDLARRKATLPVVAALNSRSEAAT
MUL_3197|M.ulcerans_Agy99 LGLAFQCVN------------------DLGRRNATLTVAAALNSRSEAAI
MMAR_0282|M.marinum_M LGLAFQIVDDLIGIWGDPARTGKPVGSDLASRKATLPIVVALSSDCEAAL
Mflv_1848|M.gilvum_PYR-GCK VGEAFQMRDDLLGVFGSPETTGKPAGDDLAARKATSVVAASYQLANDTQR
:* *** : *: * : :
MSMEG_1133|M.smegmatis_MC2_155 R-LRELLAGPIERDEDVAEALALLRRSPGLTKAKETVASYAAQAREELSH
Mvan_0992|M.vanbaalenii_PYR-1 R-LRELLATPVTDDGDLAEALRLLRASDGITKAKETVAAYAREAEQELGQ
TH_1767|M.thermoresistible__bu R-LRELVSRPVEDDADLAEALDLLRRSPGMAQATETVREYATEARSVLAQ
MLBr_02277|M.leprae_Br4923 R-LRALLAGPVDNDAEVVEALALLRASPGMARARQVLAHYADQASGELAQ
MAV_4581|M.avium_104 R-LRELLVGPIDDDEVVAEALTLLRASPGMAKAKQSLREYAAQAHRELDQ
MAB_3928c|M.abscessus_ATCC_199 R-LRVLLAAPITDDAEVEEALALLRASEGLAQAKSVVIDYADRAKAELVE
Mb3415c|M.bovis_AF2122/97 E-LAALYQAPAAMTASDVERATALVKVAGGGHVAQRCAD--ERIQAAIAA
Rv3383c|M.tuberculosis_H37Rv E-LAALYQAPAAMTASDVERATALVKVAGGGHVAQRCAD--ERIQAAIAA
MUL_3197|M.ulcerans_Agy99 E-PAALCHSGSFMATGDIDRAATLVDVAAGRHAVQRCAD--QRIQATVAA
MMAR_0282|M.marinum_M E-LARLYRSDHAMTHREVVHAAELVETAGGRQAAQHFAD--ERMRAAIAA
Mflv_1848|M.gilvum_PYR-GCK RRLGALMTGGHLTPADITHWQNLIAETGAVEWIEELIERRLTWALDSLDT
. * : . . :
MSMEG_1133|M.smegmatis_MC2_155 LP-ECPGRQALAVLVDYTISREG
Mvan_0992|M.vanbaalenii_PYR-1 LP-AGPGRQALATLVQYTINRHG
TH_1767|M.thermoresistible__bu LP-AGPGRDALATLIDFTVNRHG
MLBr_02277|M.leprae_Br4923 LP-DGPSRDALATLVDYTTNRHG
MAV_4581|M.avium_104 LP-DVPGRRALQTLVDFTISRHG
MAB_3928c|M.abscessus_ATCC_199 LP-PGDARDALGVLIEYTVRRHG
Mb3415c|M.bovis_AF2122/97 LP-DAVRSPDLIALSQLICRREC
Rv3383c|M.tuberculosis_H37Rv LP-DAVRSPDLIALSQLICRREC
MUL_3197|M.ulcerans_Agy99 LP-DAVRSRDLIALSQLICCRER
MMAR_0282|M.marinum_M LP-ESMRCSELVALAQLVIDRDK
Mflv_1848|M.gilvum_PYR-GCK ADFDGEARDALATMAAACTERVA
* .: *