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RGTDEKYGLPPQPDSDRMTRRTLPVLGLAHELITPTLRQMADRLDPHMRPVVSYHLGWSDERGRPVNNNC GKAIRPALVFVAAEAAGADPHSAIPGAVSVELVHNFSLVHDDLMDRDEHRRHRPTVWALWGDAMALLAGD AMLSLAHEVLLDCDSPHVGAALRAISEATRELIRGQAADTAFESRTDVALDECLKMAEGKTAALMAASAE VGALLAGAPRSVREALVAYGRHIGLAFQLVDDLLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSA GRRLAAWLVDETGSQTASDDELAAVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRPAAELQDLA HYIVDRQA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3398c | idsA1 | - | 100% (359) | PROBABLE MULTIFUNCTIONAL GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA1 (GGPP SYNTHETASE) (GGPPSASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE): DIMETHYLALLYLTRANSFERASE (PRENYLTRANSFERASE) (GERANYL-DIPHOSPHATE SYNTHASE) + GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FARNESYL-PYROPHOSPHATE SYNTHETASE) (FARNESYL DIPHOSPHATE SYNTHETASE) (FPP SYNTHETASE) + FARNESYLTRANSTRANSFERASE (GERANYLGERANYL-DIPHOSPHATE SYNTHASE) |
M. tuberculosis H37Rv | Rv3383c | idsB | 4e-54 | 40.74% (297) | polyprenyl synthetase IdsB |
M. tuberculosis H37Rv | Rv0562 | grcC1 | 8e-27 | 29.69% (293) | polyprenyl-diphosphate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3431c | idsA1 | 0.0 | 100.00% (359) | multifunctional dimethylallyltransferase/farnesyl |
M. gilvum PYR-GCK | Mflv_5253 | - | 5e-26 | 31.21% (298) | trans-hexaprenyltranstransferase |
M. leprae Br4923 | MLBr_02277 | - | 6e-26 | 29.41% (289) | polyprenyl diphosphate synthase component |
M. abscessus ATCC 19977 | MAB_1992c | - | 1e-27 | 28.89% (315) | polyprenyl synthetase |
M. marinum M | MMAR_5095 | idsA1 | 2e-76 | 47.09% (327) | multifunctional geranylgeranyl pyrophosphate synthetase |
M. avium 104 | MAV_4802 | - | 9e-30 | 32.96% (267) | polyprenyl synthetase |
M. smegmatis MC2 155 | MSMEG_1133 | - | 2e-26 | 30.24% (291) | bifunctional short chain isoprenyl diphosphate synthase |
M. thermoresistible (build 8) | TH_1767 | - | 6e-29 | 31.49% (289) | bifunctional short chain isoprenyl diphosphate synthase |
M. ulcerans Agy99 | MUL_3197 | idsB | 1e-33 | 36.58% (257) | polyprenyl synthetase IdsB |
M. vanbaalenii PYR-1 | Mvan_1577 | - | 2e-26 | 29.97% (307) | polyprenyl synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 MPSGTTLSSEPALRPAVMEKRRRLLHRIALCAIAAPRRIVAIAALVMVGA Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 AIFGVPVAGSLAAGGFQDPGSESARATRVLTETFGRGDMQLVFAVTDPAG Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VDSASARAAGLAIATLVGEDPAVADVVSTWTVAPEAAAALISADGRSGLV Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VAELTGDENTAPRIAQALVDEVATTVQPRHETVAVLAGGSSIVYSQINSQ Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 TLRDVLLMEAIAIPLTFLVLVWVFKGLLAAALPVAVGGLAIVASMSVLRL Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VAMWTDVSIFALNLTTALGLALAVDYTLLIVSRFRDEVAAGAPRDRALVT Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 TMVTAGRTVLFSALTVALSMAAMLLFPMYFLKSFAYAGLATVALCAVAAI Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 VVTPAVIALFGDRLDAFDIRRMLRRTPAAEPRGEQMFWYRSTKFVMRRAL Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 PVGLAGTALLVSLGLPFLGVSWGLPDDRVLPSSATAHRVGDMLRTEFSDN Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 SEAAVTVLVPDAEGLTPQDFERYAAEASTIEDVSMVSAPTGTFADGRRVG Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 PPAGGAGVQGGIAYLTVGSTTASFSPESERQLDRLRALPGPGGRPVQMTG Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 IAQINRDSVESIMARLPIVLGIIAVITFVLLFLLTGSLVLPVKALVLNAL Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 SLTAAFGALVWIFQDGNLGALGTTPTGTLVVNMPVLLFCIAFGLSMDYEV Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 FLLARIREFWLAGGRRDNDESVALGLAHTGRVVTAAALIMSISFGALIAA Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_1133|M.smegmatis_MC2_155 -------------------------------------------------- TH_1767|M.thermoresistible__bu -------------------------------------------------- MLBr_02277|M.leprae_Br4923 -------------------------------------------------- MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 QVSFMRMFGLGLMLAVLIDATLVRMVLLPAFMHLMGRWNWWAPAPLARWH Rv3398c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3431c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_5095|M.marinum_M -------------------------------------------------- MUL_3197|M.ulcerans_Agy99 -------------------------------------------------- MAV_4802|M.avium_104 -------------------------------------------------- Mflv_5253|M.gilvum_PYR-GCK --------------------------------------MRTPANVVAGVD MSMEG_1133|M.smegmatis_MC2_155 --------------------------------------------MVAGVD TH_1767|M.thermoresistible__bu --------------------------------------------VVAGVD MLBr_02277|M.leprae_Br4923 -------------------------------------------MVVAGIN MAB_1992c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_1577|M.vanbaalenii_PYR-1 ARRTGTAEQNANPTKSGAAIASNGRRRPRHGWVERGGGPQLSRGDGAGAQ Rv3398c|M.tuberculosis_H37Rv ----------------------MRGTDEKYGLPPQPDSDRMTRRTLPVLG Mb3431c|M.bovis_AF2122/97 ----------------------MRGTDEKYGLPPQPDSDRMTRRTLPVLG MMAR_5095|M.marinum_M ----------------------MAMSQMARPVRASTTPARIT----LLLN MUL_3197|M.ulcerans_Agy99 -----------------------------MTADGTCESDVPAAVVQLFLS MAV_4802|M.avium_104 ---------------------------------MMTSTLPDARPAVAALN Mflv_5253|M.gilvum_PYR-GCK FGDAQFAQDVRDGVARIEALMSEELG--------RADALMSEAVNHLFQA MSMEG_1133|M.smegmatis_MC2_155 FGDPAFAADVRDGVARIEDLMSDELG--------KADELMAEAVQHLFQA TH_1767|M.thermoresistible__bu LGDPDFAAGVRDGVARIEDLMSSELG--------KADDLMAEAVQHLFRA MLBr_02277|M.leprae_Br4923 FGDAAFAATVQDRVVRIEQLMDAELR--------DTDEVMTESVLHLFAA MAB_1992c|M.abscessus_ATCC_199 -----------------------------------------------MLR Mvan_1577|M.vanbaalenii_PYR-1 LAEPGLMAWRDTVRTAVREHLEDFVRGECARRLDGGGVDVAAELLCGFLD Rv3398c|M.tuberculosis_H37Rv LAHELITPTLRQMADRLDPHMRPVVS--------YHLGWSDERGRPVNNN Mb3431c|M.bovis_AF2122/97 LAHELITPTLRQMADRLDPHMRPVVS--------YHLGWSDERGRPVNNN MMAR_5095|M.marinum_M DIRLLIEPKQRAVIDNLSPELRLCAG--------FHIGWWEPDGRDSSVR MUL_3197|M.ulcerans_Agy99 SARAACDPVLRRAVESMPEPLATMAG--------YYLGWWDIDRSALAGS MAV_4802|M.avium_104 PLEDYLAACKQACDREIVRLYGSGER---------GSNGLYQLILDYPLR Mflv_5253|M.gilvum_PYR-GCK GGKRFRPLFTVLSAQLGPEPD---AWQVTVAGAVIELVHLATLYHDDVMD MSMEG_1133|M.smegmatis_MC2_155 GGKRFRPLFTVLSAQLGPEPD---AWQVTVAGAVIELVHLATLYHDDVMD TH_1767|M.thermoresistible__bu GGKRFRPLFTVLSAQLGPEPD---AWQVTVAGAVIELVHLATLYHDDVMD MLBr_02277|M.leprae_Br4923 GGKRFRPLFTVLSAQIGPRPD---APEVIIAGAVIELVHLASLYHDDVMD MAB_1992c|M.abscessus_ATCC_199 GGKRLRPAFAYWGWRAITDDPDPWNPEVLRVCAALELLHTCALIHDDVID Mvan_1577|M.vanbaalenii_PYR-1 GGKYVRSTYMYLGWLCGERE----DTAALRASASLELLHTFALIQDDVMD Rv3398c|M.tuberculosis_H37Rv CGKAIRPALVFVAAEAAGADP----HSAIPGAVSVELVHNFSLVHDDLMD Mb3431c|M.bovis_AF2122/97 CGKAIRPALVFVAAEAAGADP----HSAIPGAVSVELVHNFSLVHDDLMD MMAR_5095|M.marinum_M HGKAVRPALSITCARAAGGAM----DAAIPAAVAVELVHDCSLLHDDIMD MUL_3197|M.ulcerans_Agy99 SGTFVRAALVWAAAAACGGDA----GNAAPIAAAVELVHSGTLLHDDVMA MAV_4802|M.avium_104 GGKALRPALSIATCLGLGGHL----EAILPTAATLELYHNAFLIHDDIED *. .*. . :** * * :**: Mflv_5253|M.gilvum_PYR-GCK EAQVRRGAPSAN----------------ARWGNNIAILAGDYLFATASRL MSMEG_1133|M.smegmatis_MC2_155 EAQMRRGAQSAN----------------ARWGNNIAILAGDYLFATASRL TH_1767|M.thermoresistible__bu DAEMRRGAPSAN----------------AKWGNSIAILAGDYLFATASRL MLBr_02277|M.leprae_Br4923 EAEVRRGAPSAN----------------LRWSNSVAILAGDYLFATASRL MAB_1992c|M.abscessus_ATCC_199 SSATRRGEPTIHVEFAALHRENGWSGSPEQFGISAAILLGDLALTWADDM Mvan_1577|M.vanbaalenii_PYR-1 SSPMRRARPSAHVALGRWHRDRALSGSASRFGESAAILLGDLCLVWAEEM Rv3398c|M.tuberculosis_H37Rv RDEHRRHRPTVW----------------ALWGDAMALLAGDAMLSLAHEV Mb3431c|M.bovis_AF2122/97 RDEHRRHRPTVW----------------ALWGDAMALLAGDAMLSLAHEV MMAR_5095|M.marinum_M GDVTRRHRPAAW----------------VVYGVPMAILTGDALLVLALDL MUL_3197|M.ulcerans_Agy99 GEVTRGGRRAVW----------------SIWGIDNAILLGDALQTAAIRT MAV_4802|M.avium_104 ESWWRRGKPTLH----------------IDHGVPVAVNVGDAMLSLSLQP * : . *: ** : Mflv_5253|M.gilvum_PYR-GCK TSR--LGPEAVRIIADT------FALLVTGQMRETRGAADQVDSVD--HY MSMEG_1133|M.smegmatis_MC2_155 VSR--LGPDAVRVIADT------FAQLVTGQMRETRGAADHVDSVD--HY TH_1767|M.thermoresistible__bu VSR--LGPEAVRVIADT------FAQLVTGQMRETRGAADGADPIE--HY MLBr_02277|M.leprae_Br4923 VSQ--LGLDAVRIIADT------FAQLVTGQMRETRGVPEGADSIE--QY MAB_1992c|M.abscessus_ATCC_199 VVG--AQLSPEAHVRARGVWSILRSEVLGGQYLDILSESSGDESVE--TA Mvan_1577|M.vanbaalenii_PYR-1 LRR--SGVDADALARVWPRYDAMRTELAIGQLSDLLNSCQTFPTLP--EV Rv3398c|M.tuberculosis_H37Rv LLD--CDSP-HVGAALRAI-SEATRELIRGQAADTAFESRTDVALD--EC Mb3431c|M.bovis_AF2122/97 LLD--CDSP-HVGAALRAI-SEATRELIRGQAADTAFESRTDVALD--EC MMAR_5095|M.marinum_M VHE--GAS----GSALR----KAALELCAGQSADLAFEQRTKVWLP--EC MUL_3197|M.ulcerans_Agy99 LTD--LPDPGVAVRAVMRL-ETSCLDLCIGRFEDCAFECGQAGPVD--SY MAV_4802|M.avium_104 LLDNVERVGLGPALRILRAVATMTRKTVDGQALELDWVHSNTWRLDDADY *: : : Mflv_5253|M.gilvum_PYR-GCK LKVVYEKTA-CLISASGRFGATFSGSDEAQIERLAKLGGIVGTAFQISDD MSMEG_1133|M.smegmatis_MC2_155 LKVVYEKTA-CLIAASGRFGATFSGANDEQIERLSRLGGIVGTAFQIADD TH_1767|M.thermoresistible__bu LKVVYEKTA-CLISASGRFGATFSGADEEQVERLARLGGIVGTAFQISDD MLBr_02277|M.leprae_Br4923 LKVVYEKTG-CLIGSAGRLGGLFAGAHAEQVERLSRLGSIVGTAFQISDD MAB_1992c|M.abscessus_ATCC_199 LRVIRFKTAGYTVQRPLQLGVAIAGENAEISRLLGDVGLDIGIAFQLRDD Mvan_1577|M.vanbaalenii_PYR-1 LDVLRRKSGNYTVRRPLELGAAMAGCSADVADALSGYGAAIGEAFQLRDD Rv3398c|M.tuberculosis_H37Rv LKMAEGKTA-ALMAASAEVGALLAGAPRSVREALVAYGRHIGLAFQLVDD Mb3431c|M.bovis_AF2122/97 LKMAEGKTA-ALMAASAEVGALLAGAPRSVREALVAYGRHIGLAFQLVDD MMAR_5095|M.marinum_M LQMAQQKTG-ALFGVACQLGALAAGADSLVADQYAQFGRHLGLSFQLVDD MUL_3197|M.ulcerans_Agy99 ERMAAGKTA-ALIGCCCGLGALAADAGDATITALERFGRELGLAFQCVN- MAV_4802|M.avium_104 LEMVELKTSWYSFITPLQAGAVAAGSTPDRMAPLESLGRHLGAAFQITDD : *:. . * :. * :* :** : Mflv_5253|M.gilvum_PYR-GCK IIDIDSDADESGKVPGTDLREGVHTLPVLYALRETGPD------------ MSMEG_1133|M.smegmatis_MC2_155 IIDIDSDPDESGKTPGTDLREGVHTLPVLYALRETGPD------------ TH_1767|M.thermoresistible__bu IIDIESESTESGKTPGTDLREGVHTLPVLYALRETGPE------------ MLBr_02277|M.leprae_Br4923 IIDIDSDYTKSGKLPGTDVREGVRTLPILYALRETGPD------------ MAB_1992c|M.abscessus_ATCC_199 VLGVFGDPKVTGKPAGDDLRSGKRTVLLAEALRLARQRDS---------- Mvan_1577|M.vanbaalenii_PYR-1 ILGVFGSPSLTGKSVRSDLEDGKATSIVVAAYELAGPR------------ Rv3398c|M.tuberculosis_H37Rv LLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRR--------- Mb3431c|M.bovis_AF2122/97 LLGIWGRPEITGKPVYSDLRSRKKTLPVTWTVAHGGSAGRR--------- MMAR_5095|M.marinum_M ILGIWGSESVTGKPVFSDLQSRKKSLPVVAALSSGTAAGAK--------- MUL_3197|M.ulcerans_Agy99 -----------------DLGRRNATLTVAAALNSRSEAAIE--------- MAV_4802|M.avium_104 LLNLRADPQEYGKEIGGDLWEGKRTLMLLHTLRHAEPGDQQRAVQILSRR *: : : : Mflv_5253|M.gilvum_PYR-GCK -------------------------------ADRLRELLAGPVTDDADVA MSMEG_1133|M.smegmatis_MC2_155 -------------------------------ADRLRELLAGPIERDEDVA TH_1767|M.thermoresistible__bu -------------------------------AERLRELVSRPVEDDADLA MLBr_02277|M.leprae_Br4923 -------------------------------SERLRALLAGPVDNDAEVV MAB_1992c|M.abscessus_ATCC_199 ------------------------------AAEDLLHSWIGTPLTDQQVA Mvan_1577|M.vanbaalenii_PYR-1 ------------------------------LRRQLAELMQSPEIGAADVD Rv3398c|M.tuberculosis_H37Rv ------------------------------LAAWLVDETGSQTASDDELA Mb3431c|M.bovis_AF2122/97 ------------------------------LAAWLVDETGSQTASDDELA MMAR_5095|M.marinum_M ------------------------------LETLLG---GTEALSDHELS MUL_3197|M.ulcerans_Agy99 ------------------------------PAALCH---SGSFMATGDID MAV_4802|M.avium_104 RPSPDAEFDLTELLDRLTAGGQLSVSGRTEIEARLRRHHHSEVKSLNDIR :: Mflv_5253|M.gilvum_PYR-GCK EALRLLRGSQGIRKAKETVIGYAQEAQRELDQLPDVPG---RQALASLVD MSMEG_1133|M.smegmatis_MC2_155 EALALLRRSPGLTKAKETVASYAAQAREELSHLPECPG---RQALAVLVD TH_1767|M.thermoresistible__bu EALDLLRRSPGMAQATETVREYATEARSVLAQLPAGPG---RDALATLID MLBr_02277|M.leprae_Br4923 EALALLRASPGMARARQVLAHYADQASGELAQLPDGPS---RDALATLVD MAB_1992c|M.abscessus_ATCC_199 EMCSLIVDLGALGAVESRIEEHTHRALDQLAGADIADDA--RAALSDLVR Mvan_1577|M.vanbaalenii_PYR-1 RWRTLIRASGAVQWIEEQIARRHDAALRFLDGAAIPAAP--RAALAEMAV Rv3398c|M.tuberculosis_H37Rv AVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRP--AAELQDLAH Mb3431c|M.bovis_AF2122/97 AVAELIECGGGRRWASAEARRHVTQGIDMVARIGIPDRP--AAELQDLAH MMAR_5095|M.marinum_M YAADLIEDAGGRAWAEGEALRHRGLALDALAAAEPEPTA--AEDLLALAE MUL_3197|M.ulcerans_Agy99 RAATLVDVAAGR----HAVQRCADQRIQATVAALPDAVR--SRDLIALSQ MAV_4802|M.avium_104 WLYELMHRVGSLNHARDVAVRQARQAAAVLAGLDWFPRSRHRDMLAALVD *: . * : Mflv_5253|M.gilvum_PYR-GCK YTVNRHG MSMEG_1133|M.smegmatis_MC2_155 YTISREG TH_1767|M.thermoresistible__bu FTVNRHG MLBr_02277|M.leprae_Br4923 YTTNRHG MAB_1992c|M.abscessus_ATCC_199 LVSNRSA Mvan_1577|M.vanbaalenii_PYR-1 ACTQRAA Rv3398c|M.tuberculosis_H37Rv YIVDRQA Mb3431c|M.bovis_AF2122/97 YIVDRQA MMAR_5095|M.marinum_M LMTVRAA MUL_3197|M.ulcerans_Agy99 LICCRER MAV_4802|M.avium_104 YVHGRAR *