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TSVTDHTAEPAAEHTIDIHTTAGKLAELHKRRAESLHPVGEGAIEKVHAKGKLTARERIYALLDEDSFVE LDALAKHRSTNFGLESNRPVGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAVKTGR PLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVVMVDQTSQM FITGPDVIKTVTGEDVTMEELGGAHTHMVKSGTAHYVASGEQDAFEYVRELLSYLPPNNATDAPRYPAPA PEGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRILDEDEFLEIQAGYAQNIVVGFGRIEGRPVGIVA NQPTHFAGCLDIDASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTGQEYNGIIRRGAKLLYAYGEATVPK VTVITRKAYGGAYCVMGSKDMGCDVNLAWPTAQIAVMGASGAVGFVYRQQLKEAAEAGKDVDALRLQLQQ EYEDTLVNPYIAAERGYVDAVIPPSYTRGYIGTALRLLERKIAQQPPKKHGNIPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1256 | accD5 | - | 100% (546) | propionyl-CoA carboxylase beta chain 5 AccD5 |
| M. marinum M | MMAR_5363 | accD4_1 | e-135 | 47.24% (544) | propionyl-CoA carboxylase beta chain 4 AccD4_1 |
| M. marinum M | MMAR_3340 | accD6 | e-102 | 44.08% (456) | acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3308 | accD5 | 0.0 | 92.17% (549) | propionyl-CoA carboxylase beta chain |
| M. gilvum PYR-GCK | Mflv_4774 | - | 0.0 | 88.83% (537) | carboxyl transferase |
| M. tuberculosis H37Rv | Rv3280 | accD5 | 0.0 | 92.35% (549) | propionyl-CoA carboxylase beta chain |
| M. leprae Br4923 | MLBr_00731 | accD5 | 0.0 | 88.16% (549) | acetyl/propionyl CoA carboxylase beta subunit |
| M. abscessus ATCC 19977 | MAB_3631 | - | 0.0 | 84.25% (546) | propionyl-CoA carboxylase beta chain 5 AccD5 |
| M. avium 104 | MAV_4250 | - | 0.0 | 92.31% (546) | propionyl-CoA carboxylase beta chain |
| M. smegmatis MC2 155 | MSMEG_1813 | - | 0.0 | 88.83% (546) | propionyl-CoA carboxylase beta chain |
| M. thermoresistible (build 8) | TH_4304 | - | 0.0 | 88.30% (530) | PUTATIVE propionyl-CoA carboxylase beta chain |
| M. ulcerans Agy99 | MUL_2632 | accD5 | 0.0 | 99.45% (546) | propionyl-CoA carboxylase beta chain 5 AccD5 |
| M. vanbaalenii PYR-1 | Mvan_1677 | - | 0.0 | 87.91% (546) | carboxyl transferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4774|M.gilvum_PYR-GCK ---MTE-------PEASHEIDIHTTAGKLADLRKRAEEALHPVGEAAVEK
Mvan_1677|M.vanbaalenii_PYR-1 MTSVTE-------PSAEHEIDIHTTAGKLADLRKRAAEAQHPVGETAVEK
MSMEG_1813|M.smegmatis_MC2_155 MTSVTE-------PSAEHQVDIHTTAGKLADLKRRTEETLHPVGEAAVDK
MMAR_1256|M.marinum_M MTSVTD---HTAEPAAEHTIDIHTTAGKLAELHKRRAESLHPVGEGAIEK
MUL_2632|M.ulcerans_Agy99 MTSVTD---HTAEPAAEHTIDIHTTAGKLAELHKRRAESLHPVGEGAIEK
Mb3308|M.bovis_AF2122/97 MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEK
Rv3280|M.tuberculosis_H37Rv MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEK
MLBr_00731|M.leprae_Br4923 MTSVTDHSAHSMERAAEHTINIHTTAGKLAELHKRTEEALHPVGAAAFEK
MAV_4250|M.avium_104 MTSVTD---HTAEPAAEHSIDIHTTAGKLAELHKRREESLHPVGEEAVEK
TH_4304|M.thermoresistible__bu ------------------VVDLRTTAGKLADLRRRKAEAQFPVGEAAVEK
MAB_3631|M.abscessus_ATCC_1997 -MTTTESDSHTAADAAAPQPDIHTTAGKLADLRRRNEEALHPVGEAAVDK
:::*******:*::* *: .*** *.:*
Mflv_4774|M.gilvum_PYR-GCK VHAKGKLTARERILALLDEGSFVELDALAKHRSKNFGLEKNRPTGDGVVT
Mvan_1677|M.vanbaalenii_PYR-1 VHAKGKLTARERILALLDEGSFVELDALAKHRSKNFGLEHNRPTGDGVVT
MSMEG_1813|M.smegmatis_MC2_155 VHAKGKLTARERILALLDEGSFVELDALAKHRSTNFGLEKNRPLGDGVIT
MMAR_1256|M.marinum_M VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFGLESNRPVGDGVVT
MUL_2632|M.ulcerans_Agy99 VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFGLESNRPVGDGVVT
Mb3308|M.bovis_AF2122/97 VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVT
Rv3280|M.tuberculosis_H37Rv VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVT
MLBr_00731|M.leprae_Br4923 VHAKGKFTARERIYALLDDDSFVELDALARHRSTNFGLGENRPVGDGVVT
MAV_4250|M.avium_104 VHAKGKLTARERILALLDEDSFVELDALARHRSKNFGLENNRPLGDGVIT
TH_4304|M.thermoresistible__bu VHAKGKLTARERVLALLDEGSFVELDQLARHRSTNFGLADKRPLGDGVVT
MAB_3631|M.abscessus_ATCC_1997 IHAKGKLTARERIFALLDEGSFVELDALARHRSTNFGLESKRPLGDGVVT
:*****:*****: ****:.****** **:***.**.* :** ****:*
Mflv_4774|M.gilvum_PYR-GCK GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
Mvan_1677|M.vanbaalenii_PYR-1 GYGTIDGRDVCVFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MSMEG_1813|M.smegmatis_MC2_155 GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MMAR_1256|M.marinum_M GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAVKTGRPLIGIN
MUL_2632|M.ulcerans_Agy99 GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAVKTGRPLIGIN
Mb3308|M.bovis_AF2122/97 GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
Rv3280|M.tuberculosis_H37Rv GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MLBr_00731|M.leprae_Br4923 GYGTIDGRDVCIFSQDVTVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MAV_4250|M.avium_104 GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
TH_4304|M.thermoresistible__bu GYGTIDGREVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MAB_3631|M.abscessus_ATCC_1997 GFGTIDGRDVCIFSQDVSVFGGSLGEVYGEKIVKVMDLAIKTGRPLIGIN
*:******:**:****.:***************** :**:**********
Mflv_4774|M.gilvum_PYR-GCK DGAGARIQEGVVSLGLYSKIFHNNIKASGVIPQISLIMGAAAGGHVYSPA
Mvan_1677|M.vanbaalenii_PYR-1 DGAGARIQEGVVSLGLYSRIFHNNIKASGVIPQISLIMGAAAGGHVYSPA
MSMEG_1813|M.smegmatis_MC2_155 DGAGARIQEGVVSLGLYSRIFHNNIKASGVIPQISLIMGAAAGGHVYSPA
MMAR_1256|M.marinum_M DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MUL_2632|M.ulcerans_Agy99 DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
Mb3308|M.bovis_AF2122/97 DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
Rv3280|M.tuberculosis_H37Rv DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MLBr_00731|M.leprae_Br4923 DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MAV_4250|M.avium_104 DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
TH_4304|M.thermoresistible__bu DGAGARIQEGVVSLSLYSRIFHNNIRASGVIPQISLIMGAAAGGHVYSPA
MAB_3631|M.abscessus_ATCC_1997 EGAGARIQEGVVSLGLYGQIFHRNVIASGVIPQISLIMGPAAGGHVYSPA
:*************.**.:**:.*: *************.**********
Mflv_4774|M.gilvum_PYR-GCK LTDFVIMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTVHY
Mvan_1677|M.vanbaalenii_PYR-1 LTDFVIMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTVHY
MSMEG_1813|M.smegmatis_MC2_155 LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
MMAR_1256|M.marinum_M LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMVKSGTAHY
MUL_2632|M.ulcerans_Agy99 LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEEIGGAHTHMVKSGTAHY
Mb3308|M.bovis_AF2122/97 LTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHY
Rv3280|M.tuberculosis_H37Rv LTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHY
MLBr_00731|M.leprae_Br4923 LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
MAV_4250|M.avium_104 LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTLHY
TH_4304|M.thermoresistible__bu LTDFVIMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
MAB_3631|M.abscessus_ATCC_1997 LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
*****:**********************:*****:*******.**** **
Mflv_4774|M.gilvum_PYR-GCK VASGEQDALDYVRDLLSYLPPNNYAEPPRYPAPIS--GPIEENLTDEDLE
Mvan_1677|M.vanbaalenii_PYR-1 VASGEQDALDYVRDLLSYLPPNNYAEPPRYPAPHAD-APIEESLTDEDLE
MSMEG_1813|M.smegmatis_MC2_155 VASGEQDAFDYVRDLLSYLPPNNYADPPLYPVAIPE-GSIEETLTDEDLE
MMAR_1256|M.marinum_M VASGEQDAFEYVRELLSYLPPNNATDAPRYPAPAPE-GPIEENLTDEDLE
MUL_2632|M.ulcerans_Agy99 VASGEQDAFEYVRELLSYLPPNNATDAPRYPAPAPE-GPIEENLTDEDLE
Mb3308|M.bovis_AF2122/97 AASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPT-GPIEENLTDEDLE
Rv3280|M.tuberculosis_H37Rv AASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPT-GPIEENLTDEDLE
MLBr_00731|M.leprae_Br4923 VASGEQDAFDWVRDVLSYLPSNNFTDAPRYSKPVPH-GSIEDNLTAKDLE
MAV_4250|M.avium_104 VASGEQDAFDWVRDLLSYLPPNNATDPPRYAEPHPA-GAIEDNLTDEDLE
TH_4304|M.thermoresistible__bu VASGEQDAFDYVRDLLSYLPPNNYADPPRYPAPVQH-GAIEDNLTDTDLE
MAB_3631|M.abscessus_ATCC_1997 VASGEQDAFDYVRDILSYLPSNNASEPPRYPGPEPTDGAIEDHLTEEDLE
.*******:::**::*****.** ::.* * . ..**: ** ***
Mflv_4774|M.gilvum_PYR-GCK LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAGNIVVGFGRVDGRP
Mvan_1677|M.vanbaalenii_PYR-1 LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAGNIVIGFGRVDGRP
MSMEG_1813|M.smegmatis_MC2_155 LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAGNIVVGFGRVEGRP
MMAR_1256|M.marinum_M LDTLIPDSPNQPYDMHEVITRILDEDEFLEIQAGYAQNIVVGFGRIEGRP
MUL_2632|M.ulcerans_Agy99 LDTLIPDSPNQPYDMHEVITRILDEDEFLEIQAGYAQNIVVGFGRIEGRP
Mb3308|M.bovis_AF2122/97 LDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRP
Rv3280|M.tuberculosis_H37Rv LDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRP
MLBr_00731|M.leprae_Br4923 LDTLIPDSPNQPYDMHEVVTRLLDEEEFLEVQAGYATNIVVGLGRIDDRP
MAV_4250|M.avium_104 LDTLIPDSPNQPYDMHEVITRILDDDEFLEIQGGYAQNIVVGFGRIDGRP
TH_4304|M.thermoresistible__bu LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAQNIIVGFGRVDGRP
MAB_3631|M.abscessus_ATCC_1997 LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAQNIIVGFGRIDGRS
******************:**:**: ****:*.*** **::*:**::.*.
Mflv_4774|M.gilvum_PYR-GCK VGIVANQPTQFAGCLDINASEKAARFIRTCDCYNIPIVLLVDVPGFLPGT
Mvan_1677|M.vanbaalenii_PYR-1 VGIVANQPTQFAGCLDINASEKAARFIRTCDCFNIPIVLLVDVPGFLPGT
MSMEG_1813|M.smegmatis_MC2_155 VGIVANQPTQFAGCLDINASEKAARFIRTCDCFNIPIVLLVDVPGFLPGT
MMAR_1256|M.marinum_M VGIVANQPTHFAGCLDIDASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MUL_2632|M.ulcerans_Agy99 VGIVANQPTHFAGCLDIDASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
Mb3308|M.bovis_AF2122/97 VGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
Rv3280|M.tuberculosis_H37Rv VGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MLBr_00731|M.leprae_Br4923 VGIVANQPIQFAGCLDINASEKAARFVRVCDCFNIPIVMLVDVPGFLPGT
MAV_4250|M.avium_104 VGIVANQPTQFAGCLDINASEKAARFVRTCDCFNIPIIMLVDVPGFLPGT
TH_4304|M.thermoresistible__bu VGIVANQPTQFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MAB_3631|M.abscessus_ATCC_1997 VGIVANQPTQFAGCLDINASEKAARFIRTCDCFGIPIITLEDVPGFLPGT
******** :*******:********:*.***:.***: * *********
Mflv_4774|M.gilvum_PYR-GCK DQEYNGIIRRGAKLLYAYGEATVAKVTVITRKSYGGAYCVMGSKDMGADV
Mvan_1677|M.vanbaalenii_PYR-1 DQEYNGIIRRGAKLLYAYGEATVAKVTVITRKSYGGAYCVMGSKDMGADV
MSMEG_1813|M.smegmatis_MC2_155 DQEYNGIIRRGAKLLYAYGEATVAKVTVITRKSYGGAYCVMGSKDMGADV
MMAR_1256|M.marinum_M GQEYNGIIRRGAKLLYAYGEATVPKVTVITRKAYGGAYCVMGSKDMGCDV
MUL_2632|M.ulcerans_Agy99 GQEYNGIIRRGAKLLYAYGEATVPKVTVITRKAYGGAYCVMGSKDMGCDV
Mb3308|M.bovis_AF2122/97 DQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDA
Rv3280|M.tuberculosis_H37Rv DQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDV
MLBr_00731|M.leprae_Br4923 EQEYDGIIRRGAKLLFAYGEATVPKITVITRKAYGGAYCVMGSKNMGCDV
MAV_4250|M.avium_104 GQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDV
TH_4304|M.thermoresistible__bu DQEYNGIIRRGAKLLYAYGEATVAKITVITRKAYGGAYCVMGSKDMGADV
MAB_3631|M.abscessus_ATCC_1997 EQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYDVMGSKHMGADV
***:**********:*******.*:******:***** *****.**.*.
Mflv_4774|M.gilvum_PYR-GCK VVAWPTAQIAVMGASGAVGFVYRGQLKEAAANGEDVDALRLKLQQEYEDT
Mvan_1677|M.vanbaalenii_PYR-1 VVAWPTAQIAVMGASGAVGFVYRQQLREAAANGEDVDALRLKLQQEYEDT
MSMEG_1813|M.smegmatis_MC2_155 VVAWPTAQIAVMGASGAVGFVYRQQLKEAAKNGEDVDALRLELQQTYEDT
MMAR_1256|M.marinum_M NLAWPTAQIAVMGASGAVGFVYRQQLKEAAEAGKDVDALRLQLQQEYEDT
MUL_2632|M.ulcerans_Agy99 NLAWPTAQIAVMGASGAVGFVYRQQLKKAAEAGKDVDALLLQLQQEYEDT
Mb3308|M.bovis_AF2122/97 NLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDT
Rv3280|M.tuberculosis_H37Rv NLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDT
MLBr_00731|M.leprae_Br4923 NLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQLQQEYEDT
MAV_4250|M.avium_104 NIAWPSAQIAVMGASGAVGFVYRKQLAEAAKKGEDVDALRLQLQQEYEDT
TH_4304|M.thermoresistible__bu CVAWPTAQIAVMGASGAVGFVYRPQLAEAAKKGEDVDALRLRLQQEYEDT
MAB_3631|M.abscessus_ATCC_1997 NVAWPTAQIAVMGASGAVGFVYRSQLAEAAKNGDDVDALRLQLQAEYEDT
:***:***************** :* :** * ::* * *.** ****
Mflv_4774|M.gilvum_PYR-GCK LVNPYIAAERGYVDAVIPPSHTRGYVATALKLLERKVVQTPPKKHGNIPL
Mvan_1677|M.vanbaalenii_PYR-1 LVNPYIAAERGYVDAVILPSHTRGYVATALKLLERKVVQTPPKKHGNIPL
MSMEG_1813|M.smegmatis_MC2_155 LVNPYIAAERGYVDAVIPPSHTRGYVANALRLLERKIVQMPPKKHGNIPL
MMAR_1256|M.marinum_M LVNPYIAAERGYVDAVIPPSYTRGYIGTALRLLERKIAQQPPKKHGNIPL
MUL_2632|M.ulcerans_Agy99 LVNPYIAAERGYVDAVIPPSYTRGYIGTALRLLERKIAQQPPKKHGNIPL
Mb3308|M.bovis_AF2122/97 LVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL
Rv3280|M.tuberculosis_H37Rv LVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL
MLBr_00731|M.leprae_Br4923 LVNPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL
MAV_4250|M.avium_104 LVNPYVAAERGYVDAVIPPSHTRGYIATALRLLERKIAHLPPKKHGNIPL
TH_4304|M.thermoresistible__bu LVNPYIAAERGYVDAVIPPSHTRGYIATSLRLLERKIAQVPPKKHGNIPL
MAB_3631|M.abscessus_ATCC_1997 LVNPYIAAERGYVDAVIPPSHTRGYIATSLRLLDRKIVRLPPKKHGNIPL
*****:*********** **:****:..:*:**:**:.: *******:**