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MARTEGDSWDLANSVGATATMVAAARAAATRRSRPIIADPFAEPLVRAVGLDLFTRAASGEVDLDEVAAG LGFARMVDTFAARALFFDKFFADAIAAGLRQVVIVASGLDARPYRLPWPTGMRVYEIDQPEVIEFKTTTL ARLGASPTADHHPVGIDLRDDWPSALRAAGFDAARPTAWLAEGVLIGFLPPEAETRLLDNVIELSAVGSR LAADYGTINGSSAESQQLAQQMTEGWRAHGLDMDIAGLTYPGEHTDVAAYLRSHGWETATADHGDVVLAA GLAELTAADRQSPASTIGFVTAVRSTD
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_4570 | - | - | 100% (307) | hypothetical protein MMAR_4570 |
M. marinum M | MMAR_3534 | - | 3e-85 | 55.10% (294) | O-methyltransferase |
M. marinum M | MMAR_1059 | - | 4e-84 | 54.02% (311) | O-methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3816c | - | 6e-83 | 54.36% (287) | hypothetical protein Mb3816c |
M. gilvum PYR-GCK | Mflv_5023 | - | 3e-86 | 53.85% (312) | putative methyltransferase |
M. tuberculosis H37Rv | Rv3787c | - | 6e-83 | 54.36% (287) | hypothetical protein Rv3787c |
M. leprae Br4923 | MLBr_02640 | - | 4e-56 | 43.71% (286) | hypothetical protein MLBr_02640 |
M. abscessus ATCC 19977 | MAB_3787 | - | 3e-74 | 51.07% (280) | hypothetical protein MAB_3787 |
M. avium 104 | MAV_1058 | - | 1e-118 | 68.52% (305) | methyltransferase, putative, family protein |
M. smegmatis MC2 155 | MSMEG_1482 | - | 2e-84 | 53.23% (310) | methyltransferase |
M. thermoresistible (build 8) | TH_2706 | - | 7e-79 | 51.94% (310) | PUTATIVE putative methyltransferase |
M. ulcerans Agy99 | MUL_4430 | - | 1e-173 | 98.70% (307) | hypothetical protein MUL_4430 |
M. vanbaalenii PYR-1 | Mvan_1346 | - | 6e-82 | 51.43% (315) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_4570|M.marinum_M MARTEGDSWDLANSVGATATMVAAARAAATRRSRPIIADPFAEPLVRAVG MUL_4430|M.ulcerans_Agy99 MARTEGDSWDLANSVGATATMVAAARAAATRRSRPIIADPFAEPLVRAVG MAV_1058|M.avium_104 MTRSEGDTWNLASSVGATATMVAAARAAATRRPRPVLTDEYAEPLVRAVG Mb3816c|M.bovis_AF2122/97 MARTDDDSWDLATGVGATATLVAAGRARAARAAQPLIDDPFAEPLVRAVG Rv3787c|M.tuberculosis_H37Rv MARTDDDSWDLATGVGATATLVAAGRARAARAAQPLIDDPFAEPLVRAVG Mflv_5023|M.gilvum_PYR-GCK MPRTENDTWDLASSVGATATMVAAARAVATRAEDPVIDDPYAEPLVRAVG Mvan_1346|M.vanbaalenii_PYR-1 MARTDNDTWDLASSVGATATMVAAARAVATRAPRPVIDDPFAAPLVQAVG MSMEG_1482|M.smegmatis_MC2_155 MARTENDTWDLASSVGATATMVAAARALATNADEPAIDDPFAAPLVRAVG TH_2706|M.thermoresistible__bu MARSESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPLVRAVG MAB_3787|M.abscessus_ATCC_1997 MARTDDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPLVRAVG MLBr_02640|M.leprae_Br4923 -MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTG *:..*:*:: ..**.**.:*** ** : . : * :* ** .* MMAR_4570|M.marinum_M LDLFTRAASGEVD---LDEV--AAGLGFARMVDTFAARALFFDKFFADAI MUL_4430|M.ulcerans_Agy99 LDLFTRAASGEVD---LDEV--AAGLGFVRMVDTFAARALFFDKFFADAI MAV_1058|M.avium_104 LDVFTKLASGELD---PDDL--ERDVGFARMVDTFAARGRFYDDYFAAAG Mb3816c|M.bovis_AF2122/97 VEFLTRWATGELDAADVDDP--DAAWGLQRMTTELVVRTRYFDQFFLDAA Rv3787c|M.tuberculosis_H37Rv VEFLTRWATGELDAADVDDP--DAAWGLQRMTTELVVRTRYFDQFFLDAA Mflv_5023|M.gilvum_PYR-GCK IDFFAKLASGELTPEDLDVSGDESPVGMSRFADGMAARTRFFDDFFTDAC Mvan_1346|M.vanbaalenii_PYR-1 VDFFTRLATGELTTEELDTNDAESPVGMSRFADAMAARTRFFDDFFAEAM MSMEG_1482|M.smegmatis_MC2_155 VDFFTKLVDDNFDLTALDP---EAAEGLTRFANGMAARTRFFDDFFLDAA TH_2706|M.thermoresistible__bu VEFFTRLVDGDLELP-ADTA--EERAAAQVLTEVMAVRTRFFDDFFTDAT MAB_3787|M.abscessus_ATCC_1997 IEYFTKLASGAFDPEQMAGL-VQLGITADGMANGMASRTWYYDTAFESST MLBr_02640|M.leprae_Br4923 AGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAV : . . : . * ::* * : MMAR_4570|M.marinum_M AAG---LRQVVIVASGLDARPYRLPWPTGMRVYEIDQPEVIEFKTTTLAR MUL_4430|M.ulcerans_Agy99 AAG---LRQVVIVASGLDARPYRLPWPTGMRVYEIDQPEVIEFKTTTLAR MAV_1058|M.avium_104 KAG---LRQVVIVASGLDARPYRLSWPAGTTVYEIDQPEVIAFKTATLSR Mb3816c|M.bovis_AF2122/97 AAG---VRQAVILASGLDARGYRLPWPADTTVFEVDQPRVLEFKAQTLAG Rv3787c|M.tuberculosis_H37Rv AAG---VRQAVILASGLDARGYRLPWPADTTVFEVDQPRVLEFKAQTLAG Mflv_5023|M.gilvum_PYR-GCK AAG---VRQAVILASGLDARGYRLTWPEGMTLFEIDQPEVIEFKRTTLAG Mvan_1346|M.vanbaalenii_PYR-1 RAGPPPIRQGVILASGLDARAYRLSWPQDMVLFEIDQPEVLTFKAATLAD MSMEG_1482|M.smegmatis_MC2_155 RAG---VRQFVILASGLDARAYRLPWPAGSVVFEIDQPDVIEFKTKALAD TH_2706|M.thermoresistible__bu RVG---ARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKTRTLAE MAB_3787|M.abscessus_ATCC_1997 AAG---VRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVITFKTDTLAE MLBr_02640|M.leprae_Br4923 IDG---IRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAE * ** **:*****:* *** ** . ::*:*** *: :* :*: MMAR_4570|M.marinum_M LGASPTADHHPVGIDLRDDWPSALRAAGFDAARPTAWLAEGVLIGFLPPE MUL_4430|M.ulcerans_Agy99 LGASPTADHHPVGIDLRDDWPSALRAAGFDAARPTAWLAEGVRIGFLPPE MAV_1058|M.avium_104 IGAAPTAELRTIGIDLRQDWPAALQDAGFDAAQPTAWLAEGVLIGFLPPE Mb3816c|M.bovis_AF2122/97 LGAQPTADLRMVPADLRHDWPDALRRGGFDAAEPAAWIAEG-LFGYLPPD Rv3787c|M.tuberculosis_H37Rv LGAQPTADLRMVPADLRHDWPDALRRGGFDAAEPAAWIAEG-LFGYLPPD Mflv_5023|M.gilvum_PYR-GCK LGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIAEG-LLGYLPPD Mvan_1346|M.vanbaalenii_PYR-1 LGVRPSTKLATVAVDLRNDWPAALAEAGFDASAPTAWIAEG-LLGYLPPD MSMEG_1482|M.smegmatis_MC2_155 LGALPTTDRRAVAVDLRFDWPAALTEAGFDPAEPTAWIAEG-LLGYLPPE TH_2706|M.thermoresistible__bu LGAPPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEG-LLRYLPPD MAB_3787|M.abscessus_ATCC_1997 LGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEG-LLIYLPPE MLBr_02640|M.leprae_Br4923 HGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEG-LLMYLPAT *. *:: : *** *** ** .***. :.* *** : :**. MMAR_4570|M.marinum_M AETRLLDNVIELSAVGSRLAAD--YGTINGSSAESQQLAQQMTEGWRAHG MUL_4430|M.ulcerans_Agy99 AETRLLDNVIELSAVGSRLAAD--YGTINGSSAESQQLAQQMTEGWRAHG MAV_1058|M.avium_104 AEVRLLDSITPLSAEGSRFAAD--YGSLNDASQASTEQARRTTEGWRRRG Mb3816c|M.bovis_AF2122/97 AQNRLLDHVTDLSAPGSRLALEAFLGSADRDSARVEEMIRTATRGWREHG Rv3787c|M.tuberculosis_H37Rv AQNRLLDHVTDLSAPGSRLALEAFLGSADRDSARVEEMIRTATRGWREHG Mflv_5023|M.gilvum_PYR-GCK AQDRLLDTIGELSASGSRLAVESVPSQQSADQDEMREKMKDSTDRWRSHG Mvan_1346|M.vanbaalenii_PYR-1 AQDRLLDTIGELSAPGSRLAVESVPTHHEADQEELREKMKESSDRWRSHG MSMEG_1482|M.smegmatis_MC2_155 AQDRLLDQIAELSAPGSRVAVEEIPAIEEEDHEEIAARMKDFSDRWRAHG TH_2706|M.thermoresistible__bu AQDRLFDHITDLSAPGSRLATEDHPGPGAG----LGEKADELGRRWREHG MAB_3787|M.abscessus_ATCC_1997 AQDRLFASITELSAPGSRLVCEQVPGLETADFS----KARELTRQFAGET MLBr_02640|M.leprae_Br4923 AQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDALG-FE *: *: : *** ***.. : MMAR_4570|M.marinum_M LDMDIAGLTYPGE-HTDVAAYLRSHGWETATADHGDVVLAAG--LAELTA MUL_4430|M.ulcerans_Agy99 LDMDIAGLTYPGE-HTDVAAYLRSHGWKTATADHGDLVLAAG--LAELTA MAV_1058|M.avium_104 LDMDIAALTYPGK-HTDVAAHLGADGWATTTFGLADLFAAAG--LPELTE Mb3816c|M.bovis_AF2122/97 FHLDIWALNYAGP-RHEVSGYLDNHGWRSVGTTTAQLLAAHD--LPAAPA Rv3787c|M.tuberculosis_H37Rv FHLDIWALNYAGP-RHEVSGYLDNHGWRSVGTTTAQLLAAHD--LPAAPA Mflv_5023|M.gilvum_PYR-GCK FDLDFSELVFLGE-RANVPDYLRERGWAVTATPTNDLLTRYG--LAPLDT Mvan_1346|M.vanbaalenii_PYR-1 FDVDFSELVFLGE-RADVTDYLRDRGWTVDATPTNQLLTRYG--LAPLDS MSMEG_1482|M.smegmatis_MC2_155 FDLDFTELVFLGD-RADVSSYLQGHGWKTTSMTSDELLVHNG--LPRVDD TH_2706|M.thermoresistible__bu FEVQLSELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAGYGREFPDSAA MAB_3787|M.abscessus_ATCC_1997 LDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLN---LDPPN MLBr_02640|M.leprae_Br4923 QAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPM ::. * . : . * ** : . MMAR_4570|M.marinum_M ADRQSPASTIGFVTAVRSTD-- MUL_4430|M.ulcerans_Agy99 ADRQSPASTIGFVTAVRSTD-- MAV_1058|M.avium_104 AE-QGPAATLSFVRAIKS---- Mb3816c|M.bovis_AF2122/97 LP-AGLADRPNYWTCVLG---- Rv3787c|M.tuberculosis_H37Rv LP-AGLADRPNYWTCVLG---- Mflv_5023|M.gilvum_PYR-GCK DE---GFAEVVYVNAAR----- Mvan_1346|M.vanbaalenii_PYR-1 DE---GFAEVVYVSATR----- MSMEG_1482|M.smegmatis_MC2_155 DA---QIGSVVYVTATR----- TH_2706|M.thermoresistible__bu LAAMRDSSAVTAVRPVVRAGMR MAB_3787|M.abscessus_ATCC_1997 PLLRSIFPNIVYVDATLG---- MLBr_02640|M.leprae_Br4923 AD--DKDAFAEFVTAHRL----