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MPRTENDTWDLASSVGATATMVAAARAVATRAEDPVIDDPYAEPLVRAVGIDFFAKLASGELTPEDLDVS GDESPVGMSRFADGMAARTRFFDDFFTDACAAGVRQAVILASGLDARGYRLTWPEGMTLFEIDQPEVIEF KRTTLAGLGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIAEGLLGYLPPDAQDRLLDTIGELSA SGSRLAVESVPSQQSADQDEMREKMKDSTDRWRSHGFDLDFSELVFLGERANVPDYLRERGWAVTATPTN DLLTRYGLAPLDTDEGFAEVVYVNAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5023 | - | - | 100% (307) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_5025 | - | 7e-87 | 55.52% (308) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_5024 | - | 5e-79 | 53.38% (296) | putative methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0752c | - | 6e-97 | 57.24% (304) | hypothetical protein Mb0752c |
| M. tuberculosis H37Rv | Rv0731c | - | 6e-97 | 57.24% (304) | hypothetical protein Rv0731c |
| M. leprae Br4923 | MLBr_02640 | - | 2e-64 | 45.28% (307) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 7e-86 | 55.05% (307) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_3534 | - | 1e-102 | 60.06% (308) | O-methyltransferase |
| M. avium 104 | MAV_4441 | - | 1e-100 | 59.46% (296) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1482 | - | 1e-112 | 64.82% (307) | methyltransferase |
| M. thermoresistible (build 8) | TH_0301 | - | 7e-92 | 59.14% (279) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2766 | - | 1e-101 | 61.86% (291) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1346 | - | 1e-140 | 78.71% (310) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5023|M.gilvum_PYR-GCK MPRT-----ENDTWDLASSVGATATMVAAARAVATRAEDPVIDDPYAEPL
Mvan_1346|M.vanbaalenii_PYR-1 MART-----DNDTWDLASSVGATATMVAAARAVATRAPRPVIDDPFAAPL
MSMEG_1482|M.smegmatis_MC2_155 MART-----ENDTWDLASSVGATATMVAAARALATNADEPAIDDPFAAPL
MMAR_3534|M.marinum_M MPRT-----DNDSWDLATSVGATATMVAAARAIATNADNPLIADRFAEPL
MUL_2766|M.ulcerans_Agy99 MPRT-----DNDSWDLATSVGATATMVAAARAIATNADNPLIADRFAEPL
Mb0752c|M.bovis_AF2122/97 MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPL
Rv0731c|M.tuberculosis_H37Rv MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPL
MAV_4441|M.avium_104 MTST---RYEGDTWDLASSVGVTATMVAAARAMATRADNPLINDPFAEPL
TH_0301|M.thermoresistible__bu -------------------------MXGG----ASRDPKELINDPFAAPL
MAB_3787|M.abscessus_ATCC_1997 MART-----DDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPL
MLBr_02640|M.leprae_Br4923 -MRT-----HDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLL
* .. : * :* *
Mflv_5023|M.gilvum_PYR-GCK VRAVGIDFFAKLASGELTPEDLDVSG---DESPVGMSRFADGMAARTRFF
Mvan_1346|M.vanbaalenii_PYR-1 VQAVGVDFFTRLATGELTTEELDTND---AESPVGMSRFADAMAARTRFF
MSMEG_1482|M.smegmatis_MC2_155 VRAVGVDFFTKLVDDNFDLTALDP------EAAEGLTRFANGMAARTRFF
MMAR_3534|M.marinum_M VRAVGVDFFTRWVTGDLVVADVDDT-----ESGWQLAQMPDAMAVRTRFF
MUL_2766|M.ulcerans_Agy99 VRAVGVDFFTRWVTGDLVVADVDDT-----ESGWQLAQMPDAMAVRARFF
Mb0752c|M.bovis_AF2122/97 VRAVGVDFFVRMASGELDPDEL------AEDEANGLRRFADAMAIRTHYF
Rv0731c|M.tuberculosis_H37Rv VRAVGVDFFVRMASGELDPDEL------AEDEANGLRRFADAMAIRTHYF
MAV_4441|M.avium_104 VKAVGVDLLSRLAGGELDPAELNDVHDGAAGSAGAMSRMADNMAVRTKFF
TH_0301|M.thermoresistible__bu VRAVGIDFFTRIADGELTVADLDP------QSAPRVQANIDEVAVRTRFF
MAB_3787|M.abscessus_ATCC_1997 VRAVGIEYFTKLASGAFDPEQMAG----LVQLGITADGMANGMASRTWYY
MLBr_02640|M.leprae_Br4923 VTNTGAGALWEAMLDPSMVAKVEAID---AEAAAMVEHMRSYQAVRTNFF
* .* : . . : . * *: ::
Mflv_5023|M.gilvum_PYR-GCK DDFFTDACAAG---VRQAVILASGLDARGYRLTWPEGMTLFEIDQPEVIE
Mvan_1346|M.vanbaalenii_PYR-1 DDFFAEAMRAGPPPIRQGVILASGLDARAYRLSWPQDMVLFEIDQPEVLT
MSMEG_1482|M.smegmatis_MC2_155 DDFFLDAARAG---VRQFVILASGLDARAYRLPWPAGSVVFEIDQPDVIE
MMAR_3534|M.marinum_M DAFFQDATRAG---VRQAVILASGLDARAYRLDWPAGMTVFEIDQPEVIA
MUL_2766|M.ulcerans_Agy99 DAFFQDATRAG---VRQAVILASGLDARAYRLDWPAGMTVFEIDQPEVIA
Mb0752c|M.bovis_AF2122/97 DNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVID
Rv0731c|M.tuberculosis_H37Rv DNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVID
MAV_4441|M.avium_104 DEFFLNATKAG---IAQVVILASGLDARAYRLAWPAGTVVYEVDQPQVID
TH_0301|M.thermoresistible__bu DDHFAAATARG---IRQAVILAAGLDARAYRLRWPDGTVVYEIDQPRVIE
MAB_3787|M.abscessus_ATCC_1997 DTAFESSTAAG---VRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVIT
MLBr_02640|M.leprae_Br4923 DTYFNNAVIDG---IRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLA
* * : * : * ****:***:*.*** ** . ::*:*** *:
Mflv_5023|M.gilvum_PYR-GCK FKRTTLAGLGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIAEGL
Mvan_1346|M.vanbaalenii_PYR-1 FKAATLADLGVRPSTKLATVAVDLRNDWPAALAEAGFDASAPTAWIAEGL
MSMEG_1482|M.smegmatis_MC2_155 FKTKALADLGALPTTDRRAVAVDLRFDWPAALTEAGFDPAEPTAWIAEGL
MMAR_3534|M.marinum_M FKTTTLAGLGAVPRADLRTVAVDLRQDWPKALTDAGFDAGSPTAWIAEGL
MUL_2766|M.ulcerans_Agy99 FKTTTLAGLGAVPRADLRTVAVDLRQDWPKALTEAGFDAGRPTAWIAEGL
Mb0752c|M.bovis_AF2122/97 FKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGL
Rv0731c|M.tuberculosis_H37Rv FKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGL
MAV_4441|M.avium_104 FKTTALAQLGAAPTAERRVVAVDLRDDWPAALRAAGFDPTRPTAWSAEGL
TH_0301|M.thermoresistible__bu FKTRTLARLGAEPTAERRTVAADLRHDWPAALTAAGFDPAAPTVWIAEGL
MAB_3787|M.abscessus_ATCC_1997 FKTDTLAELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEGL
MLBr_02640|M.leprae_Br4923 YKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGL
:* :** *. * :. *. *** *** ** **** *.* ****
Mflv_5023|M.gilvum_PYR-GCK LGYLPPDAQDRLLDTIGELSASGSRLAVESVPSQQSADQDEMREKMKDST
Mvan_1346|M.vanbaalenii_PYR-1 LGYLPPDAQDRLLDTIGELSAPGSRLAVESVPTHHEADQEELREKMKESS
MSMEG_1482|M.smegmatis_MC2_155 LGYLPPEAQDRLLDQIAELSAPGSRVAVEEIPAIEEEDHEEIAARMKDFS
MMAR_3534|M.marinum_M FGYLPPEAQDRLLDNITALSAAGSRLACEAIPNRPQQDAEKARELMRKAT
MUL_2766|M.ulcerans_Agy99 FGYLPPEAQDRLLDNITALSATGSRLACEAIPNRPQQDAEKARELMRKAT
Mb0752c|M.bovis_AF2122/97 LGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLA
Rv0731c|M.tuberculosis_H37Rv LGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLA
MAV_4441|M.avium_104 LGYLPPEAQDRLLDTITELSAPGSRLATESAPNPAPGEEEKLKERMQAIS
TH_0301|M.thermoresistible__bu FGYLPPDAQDRLLDQITDLSAVGSRLGVEGVPAHADADEDEVRQRMRILA
MAB_3787|M.abscessus_ATCC_1997 LIYLPPEAQDRLFASITELSAPGSRLVCEQVPGLETADFSKARELTRQFA
MLBr_02640|M.leprae_Br4923 LMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVS
: **.. *** *: * *. **:. * .: : :
Mflv_5023|M.gilvum_PYR-GCK DRWRSHGFDLDFSELVFLGE-RANVPDYLRERGWAVTATPTNDLLTRYG-
Mvan_1346|M.vanbaalenii_PYR-1 DRWRSHGFDVDFSELVFLGE-RADVTDYLRDRGWTVDATPTNQLLTRYG-
MSMEG_1482|M.smegmatis_MC2_155 DRWRAHGFDLDFTELVFLGD-RADVSSYLQGHGWKTTSMTSDELLVHNG-
MMAR_3534|M.marinum_M ARWREHGFELEFGDLGYEGD-RADVALYLQDLGWQSVGTQMGQLLADNG-
MUL_2766|M.ulcerans_Agy99 ARWREHGFELEFGDLGYEGD-RADVELYLQNLGWQSVGTQMSQLLADNG-
Mb0752c|M.bovis_AF2122/97 ERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHG-
Rv0731c|M.tuberculosis_H37Rv ERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHG-
MAV_4441|M.avium_104 QRWRAHGFDLDMAGLVYFGE-RNEAAPYLAGHGWRLNSVTIRDLFAANG-
TH_0301|M.thermoresistible__bu ERWRAHGLDLDFSELIYLGD-RADVAGYLADRGWRCTALTANELLVRTG-
MAB_3787|M.abscessus_ATCC_1997 G----ETLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLN-
MLBr_02640|M.leprae_Br4923 DALG-FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGR
::. * : : * . :* ** : .
Mflv_5023|M.gilvum_PYR-GCK ---LAPLDTDEG---FAEVVYVNAAR--------
Mvan_1346|M.vanbaalenii_PYR-1 ---LAPLDSDEG---FAEVVYVSATR--------
MSMEG_1482|M.smegmatis_MC2_155 ---LPRVDDDAQ---IGSVVYVTATR--------
MMAR_3534|M.marinum_M ---AAPIPHNDDSVTMADTIYYSSVLTA------
MUL_2766|M.ulcerans_Agy99 ---AAPIPHNNDSVTMADTIYYSSVLTA------
Mb0752c|M.bovis_AF2122/97 ---LPPIDGDDAP--FGEVIYVSAELKQKHQDTR
Rv0731c|M.tuberculosis_H37Rv ---LPPIDGDDAP--FGEVIYVSAELKQKHQDTR
MAV_4441|M.avium_104 ---LDPLDDDDTR--MGEMLYTWGIYE-------
TH_0301|M.thermoresistible__bu ---LPPAENDGR---VTEVVYLSSEKSPGKRAG-
MAB_3787|M.abscessus_ATCC_1997 ---LDPPNPLLRS-IFPNIVYVDATLG-------
MLBr_02640|M.leprae_Br4923 WGDGVPMADDKDA--FAEFVTAHRL---------
. . :