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TRSEGDTWNLASSVGATATMVAAARAAATRRPRPVLTDEYAEPLVRAVGLDVFTKLASGELDPDDLERDV GFARMVDTFAARGRFYDDYFAAAGKAGLRQVVIVASGLDARPYRLSWPAGTTVYEIDQPEVIAFKTATLS RIGAAPTAELRTIGIDLRQDWPAALQDAGFDAAQPTAWLAEGVLIGFLPPEAEVRLLDSITPLSAEGSRF AADYGSLNDASQASTEQARRTTEGWRRRGLDMDIAALTYPGKHTDVAAHLGADGWATTTFGLADLFAAAG LPELTEAEQGPAATLSFVRAIKS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1058 | - | - | 100% (304) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_4441 | - | 4e-85 | 54.36% (298) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_2110 | - | 2e-84 | 54.08% (294) | methyltransferase, putative, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0752c | - | 9e-84 | 52.46% (305) | hypothetical protein Mb0752c |
| M. gilvum PYR-GCK | Mflv_5023 | - | 1e-84 | 55.74% (296) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0731c | - | 9e-84 | 52.46% (305) | hypothetical protein Rv0731c |
| M. leprae Br4923 | MLBr_02640 | - | 9e-52 | 43.60% (289) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 1e-74 | 51.75% (286) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_4570 | - | 1e-118 | 68.52% (305) | hypothetical protein MMAR_4570 |
| M. smegmatis MC2 155 | MSMEG_1482 | - | 2e-78 | 51.36% (294) | methyltransferase |
| M. thermoresistible (build 8) | TH_2706 | - | 2e-73 | 50.88% (285) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_4430 | - | 1e-117 | 68.20% (305) | hypothetical protein MUL_4430 |
| M. vanbaalenii PYR-1 | Mvan_1346 | - | 1e-80 | 51.97% (304) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4570|M.marinum_M -----MARTEGDSWDLANSVGATATMVAAARAAATRRSRPIIADPFAEPL
MUL_4430|M.ulcerans_Agy99 -----MARTEGDSWDLANSVGATATMVAAARAAATRRSRPIIADPFAEPL
MAV_1058|M.avium_104 -----MTRSEGDTWNLASSVGATATMVAAARAAATRRPRPVLTDEYAEPL
Mb0752c|M.bovis_AF2122/97 MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPL
Rv0731c|M.tuberculosis_H37Rv MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPL
Mflv_5023|M.gilvum_PYR-GCK -----MPRTENDTWDLASSVGATATMVAAARAVATRAEDPVIDDPYAEPL
Mvan_1346|M.vanbaalenii_PYR-1 -----MARTDNDTWDLASSVGATATMVAAARAVATRAPRPVIDDPFAAPL
MSMEG_1482|M.smegmatis_MC2_155 -----MARTENDTWDLASSVGATATMVAAARALATNADEPAIDDPFAAPL
MAB_3787|M.abscessus_ATCC_1997 -----MARTDDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPL
TH_2706|M.thermoresistible__bu -----MARSESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPL
MLBr_02640|M.leprae_Br4923 ------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLL
* ..*:*:: ..** **.**** ** . : * :* *
MMAR_4570|M.marinum_M VRAVGLDLFTRAASGEVDLDEVAA-----GLGFARMVDTFAARALFFDKF
MUL_4430|M.ulcerans_Agy99 VRAVGLDLFTRAASGEVDLDEVAA-----GLGFVRMVDTFAARALFFDKF
MAV_1058|M.avium_104 VRAVGLDVFTKLASGELDPDDLER-----DVGFARMVDTFAARGRFYDDY
Mb0752c|M.bovis_AF2122/97 VRAVGVDFFVRMASGELDPDELAE---DEANGLRRFADAMAIRTHYFDNF
Rv0731c|M.tuberculosis_H37Rv VRAVGVDFFVRMASGELDPDELAE---DEANGLRRFADAMAIRTHYFDNF
Mflv_5023|M.gilvum_PYR-GCK VRAVGIDFFAKLASGELTPEDLDVSGDESPVGMSRFADGMAARTRFFDDF
Mvan_1346|M.vanbaalenii_PYR-1 VQAVGVDFFTRLATGELTTEELDTNDAESPVGMSRFADAMAARTRFFDDF
MSMEG_1482|M.smegmatis_MC2_155 VRAVGVDFFTKLVDDNFDLTALDP---EAAEGLTRFANGMAARTRFFDDF
MAB_3787|M.abscessus_ATCC_1997 VRAVGIEYFTKLASGAFDPEQMAG-LVQLGITADGMANGMASRTWYYDTA
TH_2706|M.thermoresistible__bu VRAVGVEFFTRLVDGDLELPADTA---EERAAAQVLTEVMAVRTRFFDDF
MLBr_02640|M.leprae_Br4923 VTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTY
* .* : . . : . * * ::*
MMAR_4570|M.marinum_M FADAIAAG---LRQVVIVASGLDARPYRLPWPTGMRVYEIDQPEVIEFKT
MUL_4430|M.ulcerans_Agy99 FADAIAAG---LRQVVIVASGLDARPYRLPWPTGMRVYEIDQPEVIEFKT
MAV_1058|M.avium_104 FAAAGKAG---LRQVVIVASGLDARPYRLSWPAGTTVYEIDQPEVIAFKT
Mb0752c|M.bovis_AF2122/97 FLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVIDFKT
Rv0731c|M.tuberculosis_H37Rv FLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVIDFKT
Mflv_5023|M.gilvum_PYR-GCK FTDACAAG---VRQAVILASGLDARGYRLTWPEGMTLFEIDQPEVIEFKR
Mvan_1346|M.vanbaalenii_PYR-1 FAEAMRAGPPPIRQGVILASGLDARAYRLSWPQDMVLFEIDQPEVLTFKA
MSMEG_1482|M.smegmatis_MC2_155 FLDAARAG---VRQFVILASGLDARAYRLPWPAGSVVFEIDQPDVIEFKT
MAB_3787|M.abscessus_ATCC_1997 FESSTAAG---VRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVITFKT
TH_2706|M.thermoresistible__bu FTDATRVG---ARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKT
MLBr_02640|M.leprae_Br4923 FNNAVIDG---IRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKS
* : * ** **:*****:* *** ** . ::*:***.*: :*
MMAR_4570|M.marinum_M TTLARLGASPTADHHPVGIDLRDDWPSALRAAGFDAARPTAWLAEGVLIG
MUL_4430|M.ulcerans_Agy99 TTLARLGASPTADHHPVGIDLRDDWPSALRAAGFDAARPTAWLAEGVRIG
MAV_1058|M.avium_104 ATLSRIGAAPTAELRTIGIDLRQDWPAALQDAGFDAAQPTAWLAEGVLIG
Mb0752c|M.bovis_AF2122/97 TTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEG-LLG
Rv0731c|M.tuberculosis_H37Rv TTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEG-LLG
Mflv_5023|M.gilvum_PYR-GCK TTLAGLGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIAEG-LLG
Mvan_1346|M.vanbaalenii_PYR-1 ATLADLGVRPSTKLATVAVDLRNDWPAALAEAGFDASAPTAWIAEG-LLG
MSMEG_1482|M.smegmatis_MC2_155 KALADLGALPTTDRRAVAVDLRFDWPAALTEAGFDPAEPTAWIAEG-LLG
MAB_3787|M.abscessus_ATCC_1997 DTLAELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEG-LLI
TH_2706|M.thermoresistible__bu RTLAELGAPPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEG-LLR
MLBr_02640|M.leprae_Br4923 TTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEG-LLM
:*: *. *:: : :*** ***.** **** *.* *** :
MMAR_4570|M.marinum_M FLPPEAETRLLDNVIELSAVGSRLAADYG-TINGSSAE-SQQLAQQMTEG
MUL_4430|M.ulcerans_Agy99 FLPPEAETRLLDNVIELSAVGSRLAADYG-TINGSSAE-SQQLAQQMTEG
MAV_1058|M.avium_104 FLPPEAEVRLLDSITPLSAEGSRFAADYG-SLNDASQA-STEQARRTTEG
Mb0752c|M.bovis_AF2122/97 YLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLAER
Rv0731c|M.tuberculosis_H37Rv YLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLAER
Mflv_5023|M.gilvum_PYR-GCK YLPPDAQDRLLDTIGELSASGSRLAVESVPSQQSADQDEMREKMKDSTDR
Mvan_1346|M.vanbaalenii_PYR-1 YLPPDAQDRLLDTIGELSAPGSRLAVESVPTHHEADQEELREKMKESSDR
MSMEG_1482|M.smegmatis_MC2_155 YLPPEAQDRLLDQIAELSAPGSRVAVEEIPAIEEEDHEEIAARMKDFSDR
MAB_3787|M.abscessus_ATCC_1997 YLPPEAQDRLFASITELSAPGSRLVCEQVPGLETADFS----KARELTRQ
TH_2706|M.thermoresistible__bu YLPPDAQDRLFDHITDLSAPGSRLATEDHPGPGAGLGE----KADELGRR
MLBr_02640|M.leprae_Br4923 YLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVSDA
:*.. *: *: : *. **:.. :
MMAR_4570|M.marinum_M WRAHGLDMDIAGLTYPGE-HTDVAAYLRSHGWETATADHGDVVLAAGLAE
MUL_4430|M.ulcerans_Agy99 WRAHGLDMDIAGLTYPGE-HTDVAAYLRSHGWKTATADHGDLVLAAGLAE
MAV_1058|M.avium_104 WRRRGLDMDIAALTYPGK-HTDVAAHLGADGWATTTFGLADLFAAAGLPE
Mb0752c|M.bovis_AF2122/97 FRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHGLPP
Rv0731c|M.tuberculosis_H37Rv FRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHGLPP
Mflv_5023|M.gilvum_PYR-GCK WRSHGFDLDFSELVFLGE-RANVPDYLRERGWAVTATPTNDLLTRYGLAP
Mvan_1346|M.vanbaalenii_PYR-1 WRSHGFDVDFSELVFLGE-RADVTDYLRDRGWTVDATPTNQLLTRYGLAP
MSMEG_1482|M.smegmatis_MC2_155 WRAHGFDLDFTELVFLGD-RADVSSYLQGHGWKTTSMTSDELLVHNGLPR
MAB_3787|M.abscessus_ATCC_1997 FAGETLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLNLDP
TH_2706|M.thermoresistible__bu WREHGFEVQLSELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAGYGREF
MLBr_02640|M.leprae_Br4923 LG-FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWG
::. * . . : . * ** . : : .
MMAR_4570|M.marinum_M LTAADRQSPASTIGFVTAVRSTD-----
MUL_4430|M.ulcerans_Agy99 LTAADRQSPASTIGFVTAVRSTD-----
MAV_1058|M.avium_104 LTEAE-QGPAATLSFVRAIKS-------
Mb0752c|M.bovis_AF2122/97 IDGDD--APFGEVIYVSAELKQKHQDTR
Rv0731c|M.tuberculosis_H37Rv IDGDD--APFGEVIYVSAELKQKHQDTR
Mflv_5023|M.gilvum_PYR-GCK LD-TD--EGFAEVVYVNAAR--------
Mvan_1346|M.vanbaalenii_PYR-1 LD-SD--EGFAEVVYVSATR--------
MSMEG_1482|M.smegmatis_MC2_155 VD-DD--AQIGSVVYVTATR--------
MAB_3787|M.abscessus_ATCC_1997 PNPLLR-SIFPNIVYVDATLG-------
TH_2706|M.thermoresistible__bu PDSAA-LAAMRDSSAVTAVRPVVRAGMR
MLBr_02640|M.leprae_Br4923 DGVPMADDKDAFAEFVTAHRL-------
* *