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ARTDNDTWDLASSVGATATMVAAARAVATRAPRPVIDDPFAAPLVQAVGVDFFTRLATGELTTEELDTND AESPVGMSRFADAMAARTRFFDDFFAEAMRAGPPPIRQGVILASGLDARAYRLSWPQDMVLFEIDQPEVL TFKAATLADLGVRPSTKLATVAVDLRNDWPAALAEAGFDASAPTAWIAEGLLGYLPPDAQDRLLDTIGEL SAPGSRLAVESVPTHHEADQEELREKMKESSDRWRSHGFDVDFSELVFLGERADVTDYLRDRGWTVDATP TNQLLTRYGLAPLDSDEGFAEVVYVSATR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1346 | - | - | 100% (310) | putative methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1344 | - | 4e-81 | 52.87% (314) | putative methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1345 | - | 3e-80 | 53.02% (298) | putative methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0752c | - | 2e-95 | 57.47% (308) | hypothetical protein Mb0752c |
| M. gilvum PYR-GCK | Mflv_5023 | - | 1e-140 | 78.71% (310) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0731c | - | 2e-95 | 57.47% (308) | hypothetical protein Rv0731c |
| M. leprae Br4923 | MLBr_02640 | - | 2e-62 | 44.84% (310) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 6e-80 | 50.48% (311) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_3534 | - | 1e-100 | 59.81% (311) | O-methyltransferase |
| M. avium 104 | MAV_4441 | - | 1e-96 | 60.20% (299) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1482 | - | 1e-112 | 65.81% (310) | methyltransferase |
| M. thermoresistible (build 8) | TH_0301 | - | 9e-93 | 59.22% (282) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0818 | - | 6e-99 | 59.68% (310) | O-methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1346|M.vanbaalenii_PYR-1 -----MARTDNDTWDLASSVGATATMVAAARAVATRAPRPVIDDPFAAPL
Mflv_5023|M.gilvum_PYR-GCK -----MPRTENDTWDLASSVGATATMVAAARAVATRAEDPVIDDPYAEPL
MSMEG_1482|M.smegmatis_MC2_155 -----MARTENDTWDLASSVGATATMVAAARALATNADEPAIDDPFAAPL
MMAR_3534|M.marinum_M -----MPRTDNDSWDLATSVGATATMVAAARAIATNADNPLIADRFAEPL
Mb0752c|M.bovis_AF2122/97 MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPL
Rv0731c|M.tuberculosis_H37Rv MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRAPGALVNDQFAEPL
MAV_4441|M.avium_104 MTST---RYEGDTWDLASSVGVTATMVAAARAMATRADNPLINDPFAEPL
MUL_0818|M.ulcerans_Agy99 MTSTGSTRYDGDSWDLASSVGVTATMVAAARAMATRAENPLINDPYAEPL
TH_0301|M.thermoresistible__bu -----------------------------MXGGASRDPKELINDPFAAPL
MAB_3787|M.abscessus_ATCC_1997 -----MARTDDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPL
MLBr_02640|M.leprae_Br4923 ------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLL
. : * :* *
Mvan_1346|M.vanbaalenii_PYR-1 VQAVGVDFFTRLATGELTTEELDTND---AESPVGMSRFADAMAARTRFF
Mflv_5023|M.gilvum_PYR-GCK VRAVGIDFFAKLASGELTPEDLDVSG---DESPVGMSRFADGMAARTRFF
MSMEG_1482|M.smegmatis_MC2_155 VRAVGVDFFTKLVDDNFDLTALDP------EAAEGLTRFANGMAARTRFF
MMAR_3534|M.marinum_M VRAVGVDFFTRWVTGDLVVADVDDT-----ESGWQLAQMPDAMAVRTRFF
Mb0752c|M.bovis_AF2122/97 VRAVGVDFFVRMASGELDPDELA------EDEANGLRRFADAMAIRTHYF
Rv0731c|M.tuberculosis_H37Rv VRAVGVDFFVRMASGELDPDELA------EDEANGLRRFADAMAIRTHYF
MAV_4441|M.avium_104 VKAVGVDLLSRLAGGELDPAELNDVHDGAAGSAGAMSRMADNMAVRTKFF
MUL_0818|M.ulcerans_Agy99 VRAVGVDLLTRLATGEFNVADLD---DDPQRPLGPIGDVADNMAVRTRFF
TH_0301|M.thermoresistible__bu VRAVGIDFFTRIADGELTVADLD------PQSAPRVQANIDEVAVRTRFF
MAB_3787|M.abscessus_ATCC_1997 VRAVGIEYFTKLASGAFDPEQMAG----LVQLGITADGMANGMASRTWYY
MLBr_02640|M.leprae_Br4923 VTNTGAGALWEAMLDPSMVAKVEAID---AEAAAMVEHMRSYQAVRTNFF
* .* : . . : . * ** ::
Mvan_1346|M.vanbaalenii_PYR-1 DDFFAEAMRAGPPPIRQGVILASGLDARAYRLSWPQDMVLFEIDQPEVLT
Mflv_5023|M.gilvum_PYR-GCK DDFFTDACAAG---VRQAVILASGLDARGYRLTWPEGMTLFEIDQPEVIE
MSMEG_1482|M.smegmatis_MC2_155 DDFFLDAARAG---VRQFVILASGLDARAYRLPWPAGSVVFEIDQPDVIE
MMAR_3534|M.marinum_M DAFFQDATRAG---VRQAVILASGLDARAYRLDWPAGMTVFEIDQPEVIA
Mb0752c|M.bovis_AF2122/97 DNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVID
Rv0731c|M.tuberculosis_H37Rv DNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVID
MAV_4441|M.avium_104 DEFFLNATKAG---IAQVVILASGLDARAYRLAWPAGTVVYEVDQPQVID
MUL_0818|M.ulcerans_Agy99 DDFFLAATRAG---LEQVVILASGRDARAYRLPWPPQTVVYEIDLPQVID
TH_0301|M.thermoresistible__bu DDHFAAATARG---IRQAVILAAGLDARAYRLRWPDGTVVYEIDQPRVIE
MAB_3787|M.abscessus_ATCC_1997 DTAFESSTAAG---VRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVIT
MLBr_02640|M.leprae_Br4923 DTYFNNAVIDG---IRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLA
* * : * : * ****:* *:*.*** ** ::*:* * *:
Mvan_1346|M.vanbaalenii_PYR-1 FKAATLADLGVRPSTKLATVAVDLRNDWPAALAEAGFDASAPTAWIAEGL
Mflv_5023|M.gilvum_PYR-GCK FKRTTLAGLGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIAEGL
MSMEG_1482|M.smegmatis_MC2_155 FKTKALADLGALPTTDRRAVAVDLRFDWPAALTEAGFDPAEPTAWIAEGL
MMAR_3534|M.marinum_M FKTTTLAGLGAVPRADLRTVAVDLRQDWPKALTDAGFDAGSPTAWIAEGL
Mb0752c|M.bovis_AF2122/97 FKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGL
Rv0731c|M.tuberculosis_H37Rv FKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEGL
MAV_4441|M.avium_104 FKTTALAQLGAAPTAERRVVAVDLRDDWPAALRAAGFDPTRPTAWSAEGL
MUL_0818|M.ulcerans_Agy99 FKSRTLADLGAAPTADRRVVAVDLREDWPAALRAAGFDPNQPTAWSAEGL
TH_0301|M.thermoresistible__bu FKTRTLARLGAEPTAERRTVAADLRHDWPAALTAAGFDPAAPTVWIAEGL
MAB_3787|M.abscessus_ATCC_1997 FKTDTLAELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEGL
MLBr_02640|M.leprae_Br4923 YKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGL
:* :** *. * :. *. *** *** ** **** *.* ****
Mvan_1346|M.vanbaalenii_PYR-1 LGYLPPDAQDRLLDTIGELSAPGSRLAVESVPTHHEADQEELREKMKESS
Mflv_5023|M.gilvum_PYR-GCK LGYLPPDAQDRLLDTIGELSASGSRLAVESVPSQQSADQDEMREKMKDST
MSMEG_1482|M.smegmatis_MC2_155 LGYLPPEAQDRLLDQIAELSAPGSRVAVEEIPAIEEEDHEEIAARMKDFS
MMAR_3534|M.marinum_M FGYLPPEAQDRLLDNITALSAAGSRLACEAIPNRPQQDAEKARELMRKAT
Mb0752c|M.bovis_AF2122/97 LGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLA
Rv0731c|M.tuberculosis_H37Rv LGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRLA
MAV_4441|M.avium_104 LGYLPPEAQDRLLDTITELSAPGSRLATESAPNPAPGEEEKLKERMQAIS
MUL_0818|M.ulcerans_Agy99 LGYLPPEAQDRLLDTVTELSAPGSRLAAECLSGVDPAEEEQIKERMQEVS
TH_0301|M.thermoresistible__bu FGYLPPDAQDRLLDQITDLSAVGSRLGVEGVPAHADADEDEVRQRMRILA
MAB_3787|M.abscessus_ATCC_1997 LIYLPPEAQDRLFASITELSAPGSRLVCEQVPGLETADFSKARELTRQFA
MLBr_02640|M.leprae_Br4923 LMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRVS
: **.. *** *: : *. **:. * .: : :
Mvan_1346|M.vanbaalenii_PYR-1 DRWRSHGFDVDFSELVFLGE-RADVTDYLRDRGWTVDATPTNQLLTRYG-
Mflv_5023|M.gilvum_PYR-GCK DRWRSHGFDLDFSELVFLGE-RANVPDYLRERGWAVTATPTNDLLTRYG-
MSMEG_1482|M.smegmatis_MC2_155 DRWRAHGFDLDFTELVFLGD-RADVSSYLQGHGWKTTSMTSDELLVHNG-
MMAR_3534|M.marinum_M ARWREHGFELEFGDLGYEGD-RADVALYLQDLGWQSVGTQMGQLLADNG-
Mb0752c|M.bovis_AF2122/97 ERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHG-
Rv0731c|M.tuberculosis_H37Rv ERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHG-
MAV_4441|M.avium_104 QRWRAHGFDLDMAGLVYFGE-RNEAAPYLAGHGWRLNSVTIRDLFAANG-
MUL_0818|M.ulcerans_Agy99 ARWRAHGFDVDMVGLVYFGD-RNEAVPYLSDRGWLLTSTPLPELRAANG-
TH_0301|M.thermoresistible__bu ERWRAHGLDLDFSELIYLGD-RADVAGYLADRGWRCTALTANELLVRTG-
MAB_3787|M.abscessus_ATCC_1997 G----ETLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLN-
MLBr_02640|M.leprae_Br4923 DALG-FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGR
::. * : : * . :* ** : .
Mvan_1346|M.vanbaalenii_PYR-1 -LAPLDSDEG---FAEVVYVSATR----------
Mflv_5023|M.gilvum_PYR-GCK -LAPLDTDEG---FAEVVYVNAAR----------
MSMEG_1482|M.smegmatis_MC2_155 -LPRVDDDAQ---IGSVVYVTATR----------
MMAR_3534|M.marinum_M -AAPIPHNDDSVTMADTIYYSSVLTA--------
Mb0752c|M.bovis_AF2122/97 -LPPID-GDDAP-FGEVIYVSAELKQKHQDTR--
Rv0731c|M.tuberculosis_H37Rv -LPPID-GDDAP-FGEVIYVSAELKQKHQDTR--
MAV_4441|M.avium_104 -LDPLD-DDDTR-MGEMLYTWG-IYE--------
MUL_0818|M.ulcerans_Agy99 -LAPAAVDDDGP-SVDMLYVSGTLYTTPRPDPAP
TH_0301|M.thermoresistible__bu -LPPAE--NDGR-VTEVVYLSSEKSPGKRAG---
MAB_3787|M.abscessus_ATCC_1997 -LDPPNPLLRSI-FPNIVYVDATLG---------
MLBr_02640|M.leprae_Br4923 WGDGVPMADDKDAFAEFVTAHRL-----------
. :