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M. thermoresistible (build 8) TH_3647 (-)

annotation: putative transcriptional regulator, IclR family protein
coordinates: 1638499 - 1639278
length: 260

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3647--100% (260)putative transcriptional regulator, IclR family protein
M. thermoresistible (build 8)TH_2042-5e-1329.13% (230) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. thermoresistible (build 8)TH_3251-5e-0927.03% (222) PUTATIVE putative transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1802c-5e-1429.21% (202) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_0596-9e-3238.94% (226) regulatory protein, IclR
M. tuberculosis H37RvRv1773c-5e-1429.21% (202) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3295-1e-1128.02% (232) IclR family transcriptional regulator
M. marinum MMMAR_4423-2e-2031.15% (244) transcriptional regulatory protein
M. avium 104MAV_3513-2e-3640.56% (249) transcriptional regulator, IclR family protein
M. smegmatis MC2 155MSMEG_4174-1e-2129.60% (250) transcriptional regulator, IclR family protein
M. ulcerans Agy99MUL_1967-2e-1230.08% (236) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_0462-9e-3341.95% (205) regulatory proteins, IclR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0596|M.gilvum_PYR-GCK          MKASFRRRWLSVAILRAAFGFHRGKVSVMQKPP---VAG---MEHDSTGK
Mvan_0462|M.vanbaalenii_PYR-1       ----------------------------MQKPP---VAG---MEHDSTGK
MAV_3513|M.avium_104                --------------------------MPAKRAR---VAGPAAAAPAADAL
TH_3647|M.thermoresistible__bu      -----------------------------VRKR---ARG--------AIE
Mb1802c|M.bovis_AF2122/97           ------------------------------MPPTEG----------KSTT
Rv1773c|M.tuberculosis_H37Rv        ------------------------------MPPTEG----------KSTT
MAB_3295|M.abscessus_ATCC_1997      -------------------------------------------------M
MUL_1967|M.ulcerans_Agy99           -------------------------------------------------M
MMAR_4423|M.marinum_M               -----------------------------MSSGISSMIMGTGNDGGASES
MSMEG_4174|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mflv_0596|M.gilvum_PYR-GCK          LPQYPIESVDNALRLILLLGDRS-EIRLTDASEYLHVASSTAHRLLSMLQ
Mvan_0462|M.vanbaalenii_PYR-1       LPQYPIESVDNALRLILLLGDRS-EIRLTDASEYLHVASSTAHRLLSMLQ
MAV_3513|M.avium_104                APQYPIESVDNALKLLLLLGEQP-EIRLSEATRYLGVASSTAHRLLAMLA
TH_3647|M.thermoresistible__bu      RPTYLLESVDNALRLLQMLRDGG-AVRLTEAAEELGVAPSTAHRLLAMLV
Mb1802c|M.bovis_AF2122/97           NRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLV
Rv1773c|M.tuberculosis_H37Rv        NRDEGIQVLRRAVAALDEIAAEPGHLRLVDLCERLGLAKSTTRRLLVGLV
MAB_3295|M.abscessus_ATCC_1997      RQHSGIGVLDKAVQVLTAIGDSP--CGLAELCERTGLPRATAHRLAAGLE
MUL_1967|M.ulcerans_Agy99           RQDSGIGVIDKAVGLLRATAKSP--CGLAELCERTGLPRATAYRLAAALE
MMAR_4423|M.marinum_M               DPAPTVQSVDRALLVLELLADLG-KAGVTEVADELGVHKSTASRLITALE
MSMEG_4174|M.smegmatis_MC2_155      MEIAGAQSAYRVLDVLTEVSLNP-GATAGEVAKATNLTAPTAHRLLRVLC
                                              ..:  :             :      :  .*: **   * 

Mflv_0596|M.gilvum_PYR-GCK          YRGFVRQDPISRAYQPGPSLTNVAFAVHSRMDIPRTAAPILRQLVDTLQ-
Mvan_0462|M.vanbaalenii_PYR-1       YRGFVRQDPISRAYQPGPSLTNVAFAVHSRMDIPRTAAPILRRLADTLQ-
MAV_3513|M.avium_104                YRGFVRQDPVSKAYLPGPSLTGVAFAIFGRLDIARSAAPIMRALSEQLR-
TH_3647|M.thermoresistible__bu      YRGFAVQD-EKRTYLPGPALRAGPAERGWTREFTDVCLPHLEALSTVCG-
Mb1802c|M.bovis_AF2122/97           EVGLVSVDSHGRFALG---ERLLGFGSVTGAHIAAAFRPTVERVARATDG
Rv1773c|M.tuberculosis_H37Rv        EVGLVSVDSHGRFALG---ERLLGFGSVTGAHIAAAFRPTVERVARATDG
MAB_3295|M.abscessus_ATCC_1997      VHRLLSRDGDGQWQLG---AGLTELAAHVNDPLLSASAQVLPKLREITG-
MUL_1967|M.ulcerans_Agy99           VHRLLGRDEDGRWGLG---PAITELAAHVDDPLLTAGATVLPRLCETTG-
MMAR_4423|M.marinum_M               ARGYVEQLSDRGKYQLGIGVSRLARARSGHSDLVKLSQDACDKLAADLG-
MSMEG_4174|M.smegmatis_MC2_155      DRGFAIQN-DAGKYVPGPQMRVLAGDRVDRAILEELGRPLLARLRDEST-
                                                                    :          :      

Mflv_0596|M.gilvum_PYR-GCK          ETVHVGTLDGRLVRFIAALESPSAVRVISRLGSTRPAHCTSTGKVLLAGL
Mvan_0462|M.vanbaalenii_PYR-1       ETVHVGTLDGRLVRFIAALESPSAVRVISRLGGTRPAHCTSTGKVLLAGL
MAV_3513|M.avium_104                ETVHVGMLDGASVRFVAAVEGPAAVRVASRLGRALPAHCTSTGKVMLAQL
TH_3647|M.thermoresistible__bu      ETVNLVIRVGTGVRFLTSVESTAMLRVGDRRGQVLPAERTAGGRALLAEL
Mb1802c|M.bovis_AF2122/97           ETVDLSVLRGQRMWFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAAL
Rv1773c|M.tuberculosis_H37Rv        ETVDLSVLRGQRMWFVDQIESSYRLRAVSAVGLRFPLNGTANGKAALAAL
MAB_3295|M.abscessus_ATCC_1997      ESVQLYRREGTVRICVAALEPPAGLRDTVPVGSRLPMSAGSGAKVLLAHS
MUL_1967|M.ulcerans_Agy99           ESVQLYRREGTSRVCVAALEPPAGLRDTVPVGARLPMTAGSGAKVLLAHS
MMAR_4423|M.marinum_M               ETANLAILDENRAVNIVEAVSTAEIALQTWVGQSCPVHATSSGKVLLAGL
MSMEG_4174|M.smegmatis_MC2_155      ETVFLAVREGLQLTYLVVMTSSHSVQMYGEVGQQIPLHATSQGKVVLAFL
                                    *:. :          :     .  :      *   *    : .:. **  

Mflv_0596|M.gilvum_PYR-GCK          SVDELDQLYPDPHLEPLTEHSVRTLTELRTQLAEVRKSGFAISRQESEEG
Mvan_0462|M.vanbaalenii_PYR-1       SDDELDQLYPDPHLEPLTEHSVRTLTELRTQLAEVRKSGFAISNQESEEG
MAV_3513|M.avium_104                SAAELRALLPRERLKRITAHSIGSRAALETELAAIRERGYATNREESEEG
TH_3647|M.thermoresistible__bu      DDEVVERLYADR--------SAGQRAELLTELAAVREVGFGLNVEHTEEG
Mb1802c|M.bovis_AF2122/97           DDADAEAALCRL--------DPMVAEGLRREIVEIRRTGIAFDRNEHTPG
Rv1773c|M.tuberculosis_H37Rv        DDADAEAALCRL--------DPMVAEGLRREIVEIRRTGIAFDRNEHTPG
MAB_3295|M.abscessus_ATCC_1997      DPGTQAAVLP-------------GATFTERALADVRKRGWAQSAAEREAG
MUL_1967|M.ulcerans_Agy99           DPATQQAVLP-------------TAKFTDRVLAEVRRRGWAQSVAEREPG
MMAR_4423|M.marinum_M               DADEVRQRVGATLDS-FTENTIVTIDALEAQLAATRAAGWASAREELEIG
MSMEG_4174|M.smegmatis_MC2_155      PPGVGERIIDQLELARYTPSTITTAKELHEAMYEIRRDGYALNLEERELG
                                                                   :   *  * .    .   *

Mflv_0596|M.gilvum_PYR-GCK          VASVAVAVPQG-GSGIR--LALNASAPSYRFRPSDV-RKACSALKDAAAE
Mvan_0462|M.vanbaalenii_PYR-1       VASVAVAVPQG-GSGIRLALALNASAPSYRFRPSDV-RKACSALKDAAAE
MAV_3513|M.avium_104                VASVAVPIPTR-APGLR--LALNAAAPQNRLDAARY-PAVAAALVAAAKE
TH_3647|M.thermoresistible__bu      VAAFGAVVRNRLGRAVG---AVTVAVPIVRYQRHAR-GDLVRQLFRTADE
Mb1802c|M.bovis_AF2122/97           IS-AAAIARRALGDNVI---AISVPAPTARFLEKE--QRIIAALRAAADS
Rv1773c|M.tuberculosis_H37Rv        IS-AAAIARRALGDNVI---AISVPAPTARFLEKE--QRIIAALRAAADS
MAB_3295|M.abscessus_ATCC_1997      VASVSAPVRDRHGNVIA---AISVSGPIDRMGRRPG-ARWAADLVAASEA
MUL_1967|M.ulcerans_Agy99           VASVSAPVRDGRGVVVA---AISVSGPIDRIGRRPG-ARWAADLLAAADE
MMAR_4423|M.marinum_M               LNAVAAPVYDSTGRVAA---ALSVSGPAYRLPAADF-EEVAQQTIAAADA
MSMEG_4174|M.smegmatis_MC2_155      VRSVAAPVLDPSGNVVA---SVCVGGPIFRFSEDDLRGKFARMVCGTAEA
                                    :   ..      .       :: .  *  *                ::  

Mflv_0596|M.gilvum_PYR-GCK          LAVLT----------------
Mvan_0462|M.vanbaalenii_PYR-1       LARNLG---------------
MAV_3513|M.avium_104                IGDQLG---------------
TH_3647|M.thermoresistible__bu      ISVDLDGRFDSLEP-------
Mb1802c|M.bovis_AF2122/97           PDWTR----------------
Rv1773c|M.tuberculosis_H37Rv        PDWTR----------------
MAB_3295|M.abscessus_ATCC_1997      ITARL----------------
MUL_1967|M.ulcerans_Agy99           LARRL----------------
MMAR_4423|M.marinum_M               VSRGLGWTDRIS---------
MSMEG_4174|M.smegmatis_MC2_155      ITAELRRRVKPVDVLDERPAQ